Otitis

The drug Miramistin is an effective remedy for the treatment of ENT diseases. Miramistin® - official instructions for use

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Miramistin throat spray is a domestic antiseptic with an extremely wide range of applications. Gynecology, urology, traumatology, venereology, surgical practice- here is an incomplete list of areas in which this drug is considered indispensable.

In otorhinolaryngology, the medicine is used to irrigate the throat, to rinse the sinuses, and to treat otitis media.

The product has obvious advantages for consumers, who recommend using Miramistin for the throat for both children and adults.

Composition and form of Miramistin in the form of a spray

Miramistin was created at the end Soviet era as an antiseptic for use in space conditions. The resulting medicine turned out to be very simple in composition:

Benzyldimethyl ammonium chloride monohydrate - as the active ingredient;
water – as an auxiliary substance.

Externally, the solution is transparent colorless liquid, odorless and tasteless.

In the form of a throat spray, the drug is produced in 150 ml plastic bottles.

Instructions for use for adults

When purchasing a spray at a pharmacy, the consumer receives a box with a bottle of the product (closed with a sealed cap) and a separately packaged spray nozzle. Before irrigating your throat with Miramistin, you should prepare the bottle for use:

Open the bottle.
Unpack the spray system.
Insert the sprayer with a long transparent tube into the bottle.
Screw the spray nozzle clockwise.
Move the spray tube from vertical position to horizontal.
Press the nozzle several times until the medicine begins to splatter.

Instructions for using Miramistin for the throat for adults (in the form of a spray):

Take a few 2-3 sips of water before spraying.
Insert the spray tube into your mouth, pointing towards the left tonsil.
Press once.
Adjust the position of the spray wand by pointing towards back wall throat.
Press once.
Direct the spray tube to the area of the right tonsil.
Press once.

Thus, during one procedure the patient must spray 3 times on different areas of the throat mucosa. Depending on intensity inflammatory process the dosage can be adjusted - from 2 to 4 sprays at a time.

Pour the medicine into a tablespoon.
Gargle with measured volume traditional way within 30 s.
Do not swallow the solution.
At the end of the procedure, spit out the liquid.

Miramistin for gargling does not need to be diluted!

How many times can Miramistin be sprayed into a child’s throat:

Up to 6 years – one-time spraying;
up to 14 years – double spraying;
over 14 years old - in an adult dosage.

At what age can children

The instructions for use of Miramistin throat spray indicate the dosage for children starting from 3 years of age. Meanwhile, there are no contraindications for use in children over younger age not noted. This allows us to consider the 3-year age limit as conditional. It is generally accepted that from the age of 3, children begin to understand the meaning of the procedure and react more calmly to the introduction of a nebulizing tube and to the spraying of the medicine.

Pediatricians prescribe Miramistin for sore throat in a child at any age.

The main problem is how to get the product into the throat. There are 2 restrictions here:

You can’t explain to a baby that you need to open your mouth to take medicine;
It is better not to spray Miramistin into the throat of a newborn.

It is known that in babies under one year old the substance is sprayed upon contact with the mucous membrane respiratory tract can cause spasms and cause difficulty breathing.

In the case of a baby, mothers need to be guided simple rule: the main thing is that the medicine ends up in the mouth. Mixing with saliva, sooner or later the drug will spread throughout the mucous membrane of the throat, where it will have its direct effect.

How to spray Miramistin into a child’s throat? The most obvious and simple option is to spray it on the pacifier and give it to the baby. However, today not everyone uses pacifiers.

Reviews of mothers who gave Miramistin to their infants in the throat contain, for example, the following recommendation: a spray tube may well be of interest to a child who at this age likes to put everything in his mouth. Once the tube is in your baby's mouth, spray onto the tongue or the inside of the cheek. The medicine does not cause irritation and has no taste. As a rule, if spraying occurs “by accident,” the baby tolerates the procedure well.

Application for children 1, 2, 3 years old

Spasm of the larynx or trachea as a result of the drug getting into their mucous membranes can also occur at a later age. If, for example, it is necessary to spray Miramistin into the throat of a 2-year-old child, and he does not know how to hold his breath, then proceed by analogy with infants. You can spray it on your tongue or on the inside of your cheek.

Is Miramistin possible during pregnancy in the 1st, 2nd, 3rd trimester?

Instructions for use of Miramistin for the throat do not contain any special recommendations for use in pregnant women. It is known that the drug is not absorbed from the mucous membranes. Some part of it is swallowed with saliva. Information that the drug is absorbed into digestive system, absent.

Based on the available data, we can conclude that Miramistin can be used in the throat during pregnancy in any trimester, but with caution and in moderate doses.

When breastfeeding

Miramistin is one of the few antiseptics approved for use during lactation. About whether special studies on lactating women, no information available. However, given the extremely low resorption of the substance when applied topically, the likelihood of its penetration into breast milk zero.

What does Miramistin spray help with?

The drug is effective against:

Bacteria, including those resistant to other antibiotics;
fungi, including resistant species;
viruses.

The high antimicrobial activity of the drug is associated with its relatively short period of use. IN medical practice it began to be used in the 1990s. The medicine has been widely used since the 2000s. That is, Miramistin - by pharmacological standards new drug. That is why even hospital infections are sensitive to it.

The scope of the drug is wide. Included complex therapy it helps with the following diseases:

Inflammation of the mucous membrane of the respiratory tract;
inflammation of the oral mucosa;
inflammatory diseases genitourinary system both women and men;
fungal skin diseases;
disinfection of burns and wounds;
inflammatory processes in the joints.

In addition, the drug is used as a means to prevent the transmission of sexually transmitted infections.

Indications for use for sore throat

The drug does not have an analgesic effect. However, patients give good reviews about Miramistin, including use for diseases such as:

The drug is sprayed 3 times a day. The course of treatment is 4-7 days. You can use Miramistin for the throat not only as a spray, but also as a gargling solution.

The medicine is shown as antiseptic for the throat with acute sore throat. The active substance of the drug increases the permeability of the microorganism shell, thins it, leading to destruction and subsequent death. Sore throat is most often caused, less often -. Miramistin is effective against both types of bacteria.

To date, no cases of bacterial resistance to the drug have been recorded. In accordance with the instructions for use, Miramistin throat spray is effective even against hospital strains of bacteria “hardened” by quartz and antibiotics.

Upon contact with pus or blood, the drug does not reduce its activity.

Gargling with Miramistin is an alternative procedure.

Pour in a full tablespoon of undiluted medicine.
Tilt your head back a little.
Pronounce the long sound “i-i-i.”
Continue for 30 s.
Be sure to spit out all the solution.

For sore throat, the medicine is used up to 4 times a day. Total duration– up to 10 days.

Miramistin for colds and flu

Miramistin is toxic to viruses, including those that cause respiratory diseases. At the same time, the drug is not antiviral. His antiseptic effect applies only to those viruses that have not penetrated the mucosal cells and have not begun replication. For the current viral infection in an already ill person this drug does not work.

Despite this, the drug is indicated for flu and colds as a means of preventing the development bacterial infection. This is especially true in childhood, in which a bacterial complication occurs in almost 100% of cases.

In addition to antimicrobial activity, Miramistin stimulates protective function throat mucosa:

Local immunity increases;
regeneration processes are improved;
The resistance of microorganisms to other antibiotics decreases.

Miramistin can be used not only for the throat, but is also used 3-4 times a day. The course of treatment is up to 7 days.

Miramistin is indicated for otitis externa. For one reason or another (for example, from frequent exposure to water) in the external ear canal there is a violation of the integrity of the skin. Microcracks get into these microcracks and cause minor inflammation. To combat these microbes, represented by bacteria and fungi, Miramistin is used in 2 ways:

Place 1-2 drops in the ear;
moisten a cotton swab with the medicine and place it in the ear canal.

The procedure is repeated twice a day. If the patient does not have an increase in temperature, then treat otitis externa possible without the use of other means.

Instructions for use of Miramistin spray recommend using the product for herpes. However, it should be noted that in terms of the effectiveness of treating “cold” rashes on the mucous membranes, this drug is significantly inferior to special antiherpetic drugs based on acyclovir.

Analogs of Miramistin spray are cheaper

There are no direct analogs to Miramistin in the form of a throat spray.

Benzyldimethyl ammonium chloride is a development of Soviet specialists. Nowhere except Russia is a drug containing this substance produced.

Antiseptic sprays based on others active ingredients widely available in pharmacies. The cheapest of them:

However, if we compare the volume of the drug, the drugs listed above will cost about the same, and sometimes more, than Miramistin. The exception is Chlorhexidine: it is about 10 times cheaper. However, the efficiency of these analogues is significantly lower, and taste qualities some of them, judging by consumer reviews, leave much to be desired.

What is better than Miramistin

Miramistin and Chlorhexidine are similar in indications and method of administration. Chlorhexidine has the following differences:

Not recommended for children, pregnant and lactating women;
has a bitter taste;
often causes irritation.

Despite the more than attractive price of Chlorhexidine, it is better to use Miramistin to treat the throat.

Miramistin or Tantum Verde

Miramistin and are drugs that have more differences than similarities. Let's make a comparison in the table.

Table 1. Comparative characteristics Miramistina and Tantum Verde

Miramistin

Tantum Verde

On the one hand, Tantum Verde has a more comprehensive effect. On the other hand, many patients find it inconvenient frequent use drug. In addition, despite the fact that the price of Tantum Verde and Miramistin bottles is almost the same, the first remedy is enough for one course of treatment, while the second can be treated many times.

or Miramistin

Hexoral and Miramistin are drugs comparable in action and effectiveness. They are approved for use by pregnant and lactating women and do not have age restrictions by use.

The differences that are important for the consumer are presented in the table.

Table 2. Comparison of some consumer characteristics of Miromistin and Hexoral

Miramistin

Hexoral

From the patient's point of view, Hexoral has important advantages - less frequent use of the drug and a weak analgesic effect. It should be noted that the cost of Hexoral is 2 times higher than the cost of Miramistin.

Miramistin or

Miramistin for the throat has obvious advantages over Furacilin:

Spray method of applying the medicine;
high antimicrobial activity;
lack of taste;
ease of use.

However, many patients use Furacilin to gargle and speak of it as an effective, inexpensive and familiar remedy.

Date of introduction December 13, 2007 Order of the Federal Service
for supervision in the field of healthcare and social development dated 12/13/2007 No. 4785-Pr/07

Instructions for use of the drug Miramistin

Registration number:	P N001926/01
Trade name:	Miramistin ®
Chemical name:	Benzyldimethyl ammonium chloride monohydrate
Dosage form:	solution for local application.
Compound:	active substance : benzyldimethyl ammonium chloride monohydrate (Miramistin, calculated as an anhydrous substance) - 0.1 g, excipient : purified water - up to 1 liter.
Description:	colorless, clear liquid, foaming when shaken.
Pharmacotherapeutic group:	antiseptic.

ATX code:

PHARMACOLOGICAL PROPERTIES OF THE DRUG MIRAMISTIN

Miramistin has wide range antimicrobial action, including hospital strains resistant to antibiotics.
The drug has a pronounced bactericidal effect regarding gram-positive ( Staphylococcus spp., Streptococcus spp., Streptococcus pneumoniae etc.), gram-negative ( Pseudomonas aeruginosa, Miramistin can be used for children in the treatment of toys and other contact objects.">Escherichia coli, Klebsiella spp., etc.), aerobic and anaerobic bacteria, defined as monocultures and microbial associations, including hospital strains with multidrug resistance to antibiotics.
Has an antifungal effect on ascomycetes of the genus Aspergillus and genus Penicillium, yeast ( Rhodotorula rubra, Torulopsis gabrata etc.) and yeast-like fungi ( Candida albicans, Candida tropicalis, Candida krusei, Pityrosporum orbiculare (Malassezia furfur) etc.), dermatophytes ( Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton verrucosum, Trichophyton schoenleini, Trichophyton violacent, Epidermophyton Kaufman-Wolf, Epidermophyton floccosum, Microsporum gypseum, Microsporum canis etc.), as well as other pathogenic fungi, in the form of monocultures and microbial associations, including fungal microflora with resistance to chemotherapy drugs.
Possesses antiviral effect, is active against complex viruses (medical antiseptics are actively used to prevent influenza."> herpes viruses, prevention after accidental relationships is possible with the use of the antiseptic Miramistin"> human immunodeficiency virus, etc.).
Miramistin acts on pathogens of sexually transmitted diseases ( Chlamydia spp., Treponema spp., Trichomonas vaginalis, Neisseria gonorrhoeae, etc.).

Effectively prevents infection of wounds and burns. Activates regeneration processes. Stimulates defensive reactions at the site of application, due to the activation of the absorption and digestive functions of phagocytes, it potentiates the activity of the monocyte-macrophage system. It has pronounced hyperosmolar activity, as a result of which it stops wound and perifocal inflammation, absorbs purulent exudate, promoting the formation of a dry scab. Does not damage granulations and viable skin cells, does not inhibit marginal epithelialization.
Does not have a local irritant effect or allergenic properties.
Pharmacokinetics. When applied topically, Miramistin does not have the ability to be absorbed through the skin and mucous membranes.

Indications for use

Otorhinolaryngology: complex treatment of acute and chronic otitis, sinusitis, tonsillitis, laryngitis, pharyngitis. In children aged 3 to 14 years, it is used for the complex treatment of acute pharyngitis and/or exacerbation of chronic tonsillitis.

Dentistry: treatment and prevention of infectious diseases inflammatory diseases oral cavity: stomatitis, gingivitis, periodontitis, periodontitis. Hygienic treatment of removable dentures.

Surgery, traumatology: prevention of suppuration and treatment purulent wounds. Treatment of purulent-inflammatory processes of the musculoskeletal system.

Obstetrics-gynecology: prevention and treatment of suppuration of postpartum injuries, wounds of the perineum and vagina, postpartum infections, inflammatory diseases (vulvovaginitis, endometritis).

Combustiology: treatment of superficial and deep burns of II and IIIA degrees, preparation burn wounds to dermatoplasty.

Dermatology, venereology: treatment and prevention of pyoderma and dermatomycosis, candidiasis of the skin and mucous membranes, mycoses of the feet. Individual prevention sexually transmitted diseases (syphilis, Miramistin instructions contain a sequence of actions for emergency prevention gonorrhea.">gonorrhea, chlamydia, trichomoniasis, genital herpes in the intimate area). In most cases, HSV virus carriage is asymptomatic, since simultaneously with infection the human body begins to produce antibodies that do not allow HSV to actively multiply.">herpes, genital candidiasis etc.).

Urology: complex treatment of acute and chronic urethritis and urethroprostatitis of specific (chlamydia, trichomoniasis, gonorrhea) and nonspecific nature.

Contraindications. Individual intolerance to the drug.

METHOD OF APPLICATION AND DOSES OF MIRAMISTIN

The drug is ready for use.

Instructions for using the packaging with spray nozzle:

Remove the cap from the bottle and also remove the urological applicator from the 50 ml bottle.
Remove the supplied spray nozzle from its protective packaging.
Attach the spray nozzle to the bottle.
Activate the spray nozzle by pressing again.

Directions for using the 50 ml or 100 ml pack with gynecological attachment:

Remove the cap from the bottle.
Remove the supplied gynecological attachment from the protective packaging.
Attach the gynecological nozzle to the bottle without removing the urological applicator.

Otorhinolaryngology.

For purulent sinusitis - during puncture maxillary sinus washed with a sufficient amount of the drug.

Tonsillitis, pharyngitis and laryngitis are treated by gargling and/or irrigation using a spray nozzle, pressing 3-4 times, 3-4 times a day. The amount of drug per rinse is 10-15 ml.

In children. At acute pharyngitis and/or exacerbation chronic tonsillitis The pharynx is irrigated using a spray nozzle. Children aged 3-6 years: by pressing the head of the spray nozzle once (3-5 ml per irrigation), 3-4 times a day; for children aged 7-14 years, double pressing (5-7 ml per irrigation), 3-4 times a day; for children over 14 years old, press 3-4 times (10-15 ml per irrigation), 3-4 times a day. The duration of therapy ranges from 4 to 10 days, depending on the timing of remission.

Dentistry.

For stomatitis, gingivitis, periodontitis, it is recommended to rinse the mouth with 10-15 ml of the drug, 3-4 times a day.

Surgery, traumatology, combustiology.

With preventive and therapeutic purpose irrigate the surface of wounds and burns, loosely pack wounds and fistula tracts, fix gauze swabs soaked in the drug. Treatment procedure repeated 2-3 times a day for 3-5 days. A highly effective method of active drainage of wounds and cavities with a daily consumption of up to 1 liter of the drug.

Obstetrics, gynecology.

For the purpose of prevention postpartum infection used in the form of vaginal irrigation before childbirth (5-7 days), during childbirth after each vaginal examination and in postpartum period 50 ml of the drug in the form of a tampon with an exposure of 2 hours, for 5 days. For the convenience of vaginal irrigation, Miramistin is also used in the treatment of many diseases.">Irrigation is recommended for use gynecological attachment. Insert the contents of the bottle into the vagina using a gynecological nozzle and perform irrigation.

When women give birth by caesarean section, immediately before the operation the vagina is treated, during the operation - the uterine cavity and the incision on it, and in postoperative period insert tampons soaked in the drug into the vagina with an exposure of 2 hours for 7 days. Treatment of inflammatory diseases is carried out over a course of 2 weeks by intravaginal administration of tampons with the drug, as well as by the method of medicinal electrophoresis.

Venereology.

For prevention venereal diseases the drug is effective if it is used no later than 2 hours after sexual intercourse. The contents of the bottle must be administered using a urological applicator; for men, Miramistin must be administered. "> urethra for 2-3 minutes: for men (2-3 ml), women (1-2 ml) and in the vagina (5-10 ml). For convenience, the use of a gynecological attachment is recommended. Treat leather internal surfaces thighs, pubis, genitals. After the procedure, it is recommended not to urinate for 2 hours.

Urology.

IN complex treatment for urethritis and urethroprostatitis, 2-3 ml of the drug is injected into the urethra 1-2 times a day, the course is 10 days.

Side effect.

IN in some cases A slight burning sensation may occur at the site of application, which goes away on its own after 15-20 seconds and does not require discontinuation of the drug. Allergic reactions.

Interaction with other drugs.

When used simultaneously with Miramistin, it is not an antibiotic; an increase in their antibacterial and antifungal properties is noted.

Release forms of Miramistin.

Solution for topical use 0.01%.
Polyethylene bottles with a urological applicator with a screw cap, 50 ml, 100 ml.
50 ml polyethylene bottles with a urological applicator with a screw cap, complete with a spray nozzle.
Polyethylene bottles 50 ml, 100 ml with a urological applicator with a screw-on cap, complete with a gynecological nozzle.
Polyethylene bottles 100 ml, 150 ml, 200 ml complete with a spray nozzle or equipped with a spray pump and a protective cap.
500 ml polyethylene bottles with a screw cap with first opening control.

Miramistin solution is one of the domestic antiseptics. The development of this effective tool was carried out back in the 70s of the last century by Professor Krivoshein and a group of researchers from Russia and Ukraine.

Due to various political events in the USSR scientific work often stopped due to lack of funding.

Therefore, the drug was registered as a medicinal product only in 1991.

Composition with description of components

Miramistin in the form of a solution is a clear liquid without a distinct odor. Main

Active ingredient formula

component medication is benzyldimethyl ammonium chloride monohydrate, purified water is also present.

The antiseptic is produced in opaque bottles of 150 ml. There are also bottles equipped with different spray nozzles depending on the area of application of the medicinal composition.

Pharmacological effect

The drug has a powerful antiseptic effect and effectively fights various pathogenic organisms. It is able to neutralize streptococci and staphylococci, and also destroys the following types of pathogenic bacteria:

spore-forming;
gram-positive and gram-negative;
asporogenous;
aerobic;
anaerobic.

This antiseptic also affects a number of microorganisms that provoke sexually transmitted diseases, namely, it destroys the following types of bacteria:

chlamydia;
Treponema;
Trichomonas;
gonococci.

In addition, the composition is widely used for fungal diseases and for wound healing.

Indications for use in dentistry and ENT practice

Miramistin solution is used in many branches of medicine, including dentistry (for topical use and rinsing) and in otorhinolaryngology (for ENT diseases) for gargling.

Indications for use in dental practice are the following diseases:

other infectious origin.

The solution is also widely used for antibacterial treatment.

In otorhinolaryngology, Miramistin solution is used to gargle the throat, nasal cavity and oral mucosa for the following diseases:

sinusitis;
otitis;
laryngitis;
pharyngitis;
tonsillitis;
angina.

The dosage and regimen depends on the nature of the disease and individual characteristics patient.

The drug should not be used if you are hypersensitive active ingredients medicine.

Application in other areas of medicine

Miramistin solution has found application in other areas of medicine:

Venereology and dermatology. The product is effective against dermatomycosis, pyoderma, candidiasis skin and mucous membranes, as well as with thrush of the genital organs.
Obstetrics and gynecology. It is used in the treatment of diseases of the genital organs of an infectious and inflammatory nature, as well as for the treatment of injuries received during childbirth.
Urology. Prescribed for urethritis and urethroprostatitis in acute and chronic form.
Traumatology and surgery. Indicated as a preventive and remedy against the suppuration of wounds, as well as for diseases musculoskeletal system purulent-inflammatory origin.

In addition, the drug is used as a means for the prevention of sexually transmitted diseases and in the treatment of burns.

Application and dosage regimen

Features of the use of Miramistin will depend on the field of medicine and the specific disease.

Dental field

In dental practice, the antiseptic Miramistin in the form of a solution is used in accordance with the following recommendations and instructions:

at And treatment with the composition is advisable only after the enamel has been cleaned of and;
during treatment, the product is used for rinsing in combination with immunomodulatory and antiviral drugs, the procedure is carried out 3 times a day for 1 minute;
after or autopsy“baths” with an antiseptic are shown: you need to take a tablespoon of solution into your mouth and hold for at least 1 minute;
at fungal diseases of the oral cavity Miramistin is used both for rinsing the mouth and throat, and for topical use to treat the mucous membrane with a cotton swab;
in order to disinfect, you need to first clean them and then apply an antiseptic.

For ENT diseases, the drug is used for rinsing and local processing, as well as when rinsing the nose. It is necessary to use an antiseptic 3-4 times a day, 10-15 ml of the product per 1 procedure. Dosages and dosage regimens may vary depending on the nature of the disease and the age of the patient.

In other branches of medicine, the product is used for external treatment or as a liquid for douching (for example, in the treatment gynecological diseases or prevention of sexually transmitted infections).

Use in childhood

Prescribing the drug to children under 3 years of age is prohibited. In other cases, for dental and otorhinolaryngological diseases, the drug is used 3-4 times a day in the following dosages:

age from 3 to 6 years– 4–5 ml of the substance per procedure;
age from 7 to 14 years– 5–7 ml per application;
age from 14 years– 10–15 ml at a time.

The course of treatment is 4–10 days, depending on the nature of the disease and the condition of the child.

Application by women - goals and methods

The drug was found wide application in obstetrics and gynecology. Miramistin solution is used in a number of cases, including:

as a solution for douching for fungal and bacterial infections (in some cases best effect achieved from the use of tampons with a solution);
How prophylactic against the development of infections after childbirth (tampons are placed in the vagina for 1.5–2 hours daily, the course of therapy is 7 days, douching is also possible);
for processing the incision during caesarean section;
for the prevention of sexually transmitted diseases (the solution should be inserted into the vagina no later than 1.5–2 hours after sexual intercourse).

Some patients noted a slight burning sensation in the vagina after using the drug, but in most cases the composition was well tolerated.

Side effects and special instructions

When used in dental, otorhinolaryngological and gynecological practice, the drug may cause a slight short-term burning sensation.

When treating the skin, in some cases redness and itching occurs, but there is no need to discontinue the drug.

If the medication is applied to a large area of skin, it can penetrate into the blood, which increases bleeding. In such situations, it is better to discontinue the drug.

When using an antiseptic, it is important to prevent it from getting into your eyes. If such a problem occurs, the solution is washed off a large number water, and to avoid possible problems, you should visit a doctor.

We asked - we answer

The most popular questions on the topic of using Miramistin in certain cases.

Can Miramistin be used during pregnancy?

This drug is indicated for use during pregnancy and lactation only as prescribed by a doctor. It is most often used as a rinse or for nasal drops.

How to properly gargle with an antiseptic?

Most often, the volume of rinsing product does not exceed 20 ml at a time. You need to keep the solution in your mouth for at least 1 minute and carry out the procedure 3 to 4 times a day. More detailed instructions can be obtained from your doctor in accordance with the characteristics of the disease.

What to do if you accidentally swallowed the composition?

If during the procedure part of the drug was swallowed, it is necessary to monitor the patient’s condition and seek medical help if the condition worsens at the slightest.

How to treat your nose with Miramistin?

Most often the nasal mucosa is treated a small amount drug (you can use a spray nozzle). The frequency of procedures and the permitted dosage are determined by the attending physician.

Is antiseptic dangerous for infants?

The drug is prohibited for use in children under 3 years of age. But in some cases, doctors recommend using Miramistin for external treatment areas of the baby's body that need disinfection. You cannot use the drug without the permission of a specialist.

I have an opinion

Doctor's opinion and patient reviews about the effectiveness and safety of Miramistin in the form of a solution.

I am a pediatrician and recommend Miramistin for treatment oral cavity for sore throats and ARVI. This composition copes well with pathogenic bacteria, does not cause allergies and is practically tasteless and odorless. This is very important for young patients.

Pediatrician, 21 years of practice

I often get a sore throat and in such cases this solution is a first aid remedy for me. In addition to a weak throat, I also have allergies; before I tried Miramistin, I was exhausted with by different means. And this antiseptic suited me perfectly, I am satisfied.

Alina, 34

The dentist prescribed this composition to me, but I didn’t want to use it, I only tried it once. To be honest, I was confused by the low price, only 150 rubles. Can good and safe remedy is it so cheap?

Nina, 41

Purchase and analogues

The price of the solution depends on the volume of packaging and the manufacturing company; on average, Miramistin costs from 140–270 rubles. You can buy it at any pharmacy without a prescription.

The shelf life of the composition is 3 years.

It must be stored out of the reach of children at temperatures up to 25 degrees.

Analogues of the drug include the following antiseptics:

Dekasan;
Octenisept.

Their cost may vary both up and down.

However, what drug can be used to replace Miramistin in a given situation must be decided by the attending physician.

Date of introduction December 13, 2007 Order of the Federal Service
on supervision in the field of healthcare and social development dated December 13, 2007 No. 4785-Pr/07

Instructions for use of the drug Miramistin

Registration number:	P N001926/01
Trade name:	Miramistin ®
Chemical name:	Benzyldimethyl ammonium chloride monohydrate
Dosage form:	solution for topical use.
Compound:	active substance: benzyldimethyl ammonium chloride monohydrate (Miramistin, calculated as an anhydrous substance) - 0.1 g, excipient: purified water - up to 1 liter.
Description:	colorless, transparent liquid, foaming when shaken.
Pharmacotherapeutic group:	antiseptic.

ATX code:

PHARMACOLOGICAL PROPERTIES OF THE DRUG MIRAMISTIN

Miramistin has a wide spectrum of antimicrobial action, including hospital strains resistant to antibiotics.
The drug has a pronounced bactericidal effect against gram-positive ( Staphylococcus spp., Streptococcus spp., Streptococcus pneumoniae, etc.), gram-negative ( Pseudomonas aeruginosa, Miramistin can be used for children in the treatment of toys and other contact objects.">Escherichia coli, Klebsiella spp., etc.), aerobic and anaerobic bacteria, defined as monocultures and microbial associations, including hospital strains with multidrug resistance to antibiotics.
Has an antifungal effect on ascomycetes of the genus Aspergillus and genus Penicillium, yeast ( Rhodotorula rubra, Torulopsis gabrata etc.) and yeast-like fungi ( Candida albicans, Candida tropicalis, Candida krusei, Pityrosporum orbiculare (Malassezia furfur) etc.), dermatophytes ( Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton verrucosum, Trichophyton schoenleini, Trichophyton violacent, Epidermophyton Kaufman-Wolf, Epidermophyton floccosum, Microsporum gypseum, Microsporum canis etc.), as well as other pathogenic fungi, in the form of monocultures and microbial associations, including fungal microflora with resistance to chemotherapeutic drugs.
It has an antiviral effect, is active against complex viruses (medical antiseptics are actively used to prevent influenza.">herpes viruses, prevention after accidental relationships is possible with the use of the antiseptic Miramistin">human immunodeficiency virus, etc.).
Miramistin acts on pathogens of sexually transmitted diseases ( Chlamydia spp., Treponema spp., Trichomonas vaginalis, Neisseria gonorrhoeae, etc.).

Effectively prevents infection of wounds and burns. Activates regeneration processes. Stimulates protective reactions at the site of application, due to the activation of the absorption and digestive functions of phagocytes, potentiates the activity of the monocyte-macrophage system. It has pronounced hyperosmolar activity, as a result of which it stops wound and perifocal inflammation, absorbs purulent exudate, promoting the formation of a dry scab. Does not damage granulations and viable skin cells, does not inhibit marginal epithelialization.
Does not have a local irritant effect or allergenic properties.
Pharmacokinetics. When applied topically, Miramistin does not have the ability to be absorbed through the skin and mucous membranes.

Indications for use

Dentistry: treatment and prevention of infectious and inflammatory diseases of the oral cavity: stomatitis, gingivitis, periodontitis, periodontitis. Hygienic treatment of removable dentures.

Surgery, traumatology: prevention of suppuration and treatment of purulent wounds. Treatment of purulent-inflammatory processes of the musculoskeletal system.

Combustiology: treatment of superficial and deep burns of II and IIIA degrees, preparation of burn wounds for dermatoplasty.

Dermatology, venereology: treatment and prevention of pyoderma and dermatomycosis, candidiasis of the skin and mucous membranes, mycoses of the feet. Individual prevention of sexually transmitted diseases (syphilis, Miramistin's instructions contain a sequence of actions for emergency prevention of gonorrhea.">gonorrhea, chlamydia, trichomoniasis, genital herpes in the intimate area). In most cases, HSV virus carriage is asymptomatic, since simultaneously with infection the body a person begins to produce antibodies that do not allow HSV to actively multiply."> herpes, genital candidiasis, etc.).

Urology: complex treatment of acute and chronic urethritis and urethroprostatitis of specific (chlamydia, trichomoniasis, gonorrhea) and nonspecific nature.

Contraindications. Individual intolerance to the drug.

METHOD OF APPLICATION AND DOSES OF MIRAMISTIN

The drug is ready for use.

Instructions for using the packaging with spray nozzle:

Remove the cap from the bottle and also remove the urological applicator from the 50 ml bottle.
Remove the supplied spray nozzle from its protective packaging.
Attach the spray nozzle to the bottle.
Activate the spray nozzle by pressing again.

Directions for using the 50 ml or 100 ml pack with gynecological attachment:

Remove the cap from the bottle.
Remove the supplied gynecological attachment from the protective packaging.
Attach the gynecological nozzle to the bottle without removing the urological applicator.

Otorhinolaryngology.

For purulent sinusitis, during puncture the maxillary sinus is washed with a sufficient amount of the drug.

Tonsillitis, pharyngitis and laryngitis are treated by gargling and/or irrigation using a spray nozzle, pressing 3-4 times, 3-4 times a day. The amount of drug per rinse is 10-15 ml.

In children. In case of acute pharyngitis and/or exacerbation of chronic tonsillitis, the pharynx is irrigated using a spray nozzle. Children aged 3-6 years: by pressing the head of the spray nozzle once (3-5 ml per irrigation), 3-4 times a day; for children aged 7-14 years, double pressing (5-7 ml per irrigation), 3-4 times a day; for children over 14 years old, press 3-4 times (10-15 ml per irrigation), 3-4 times a day. The duration of therapy ranges from 4 to 10 days, depending on the timing of remission.

Dentistry.

For stomatitis, gingivitis, periodontitis, it is recommended to rinse the mouth with 10-15 ml of the drug, 3-4 times a day.

Surgery, traumatology, combustiology.

For preventive and therapeutic purposes, the surface of wounds and burns is irrigated, wounds and fistula tracts are loosely tamponed, gauze swabs soaked in the drug are fixed. The treatment procedure is repeated 2-3 times a day for 3-5 days. A highly effective method of active drainage of wounds and cavities with a daily consumption of up to 1 liter of the drug.

Obstetrics, gynecology.

In order to prevent postpartum infection, it is used in the form of vaginal irrigation before childbirth (5-7 days), during childbirth after each vaginal examination and in the postpartum period, 50 ml of the drug in the form of a tampon with an exposure of 2 hours, for 5 days. For the convenience of vaginal irrigation, Miramistin is also used in the treatment of many diseases.

When women give birth by cesarean section, immediately before the operation the vagina is treated, during the operation - the uterine cavity and the incision on it, and in the postoperative period, tampons soaked in the drug are inserted into the vagina with an exposure of 2 hours for 7 days. Treatment of inflammatory diseases is carried out over a course of 2 weeks by intravaginal administration of tampons with the drug, as well as by the method of medicinal electrophoresis.

Venereology.

For the prevention of sexually transmitted diseases, the drug is effective if it is used no later than 2 hours after sexual intercourse. The contents of the bottle must be administered using a urological applicator; for men, Miramistin must be administered. ">urethra for 2-3 minutes: for men (2-3 ml), women (1-2 ml) and in the vagina (5-10 ml). For convenience, it is recommended to use a gynecological attachment. Treat the skin of the inner thighs, pubis, genitals. After the procedure, it is recommended not to urinate for 2 hours.

Urology.

In the complex treatment of urethritis and urethroprostatitis, 2-3 ml of the drug is injected into the urethra 1-2 times a day, the course is 10 days.

Side effect.

In some cases, a slight burning sensation may occur at the site of application, which goes away on its own after 15-20 seconds and does not require discontinuation of the drug. Allergic reactions.

Interaction with other drugs.

When used simultaneously with Miramistin, it is not an antibiotic; an increase in their antibacterial and antifungal properties is noted.

Release forms of Miramistin.

Solution for topical use 0.01%.
Polyethylene bottles with a urological applicator with a screw cap, 50 ml, 100 ml.
50 ml polyethylene bottles with a urological applicator with a screw cap, complete with a spray nozzle.
Polyethylene bottles 50 ml, 100 ml with a urological applicator with a screw-on cap, complete with a gynecological nozzle.
Polyethylene bottles 100 ml, 150 ml, 200 ml complete with a spray nozzle or equipped with a spray pump and a protective cap.
500 ml polyethylene bottles with a screw cap with first opening control.