Viferon suppositories (rectal suppositories). Viferon candles: instructions for use and reviews from people

Childhood – anxious time for the mother, since it is at this time that the baby encounters many infections around him. Not always children's body can cope with them on their own, and with reduced immunity, diseases are guaranteed.

As a rule, all infectious diseases in children occur with fever; children tolerate it very poorly. viral infections, especially seasonal ones. Viruses mutate rapidly, therefore, having had the flu at the beginning of winter, a child may get sick several more times during these cold months. To increase the body's defenses, protect the baby from diseases and help cure existing diseases, you can use effective means Viferon.

Basic information about the drug and composition

The drug Viferon contains human recombinant alpha2b-interferon, which significantly increases the body's defenses. Available in several dosage forms, but Viferon in suppositories, which is available with different content alpha2b-interferon, measured in international units (IU).

To distinguish the dosage, just look at the color stripe on the package of candles:

• 150000 IU - blue;
• 500000 IU - green;
• 1,000,000 IU - purple;
• 5000000 IU - red.

The drug is prescribed both independently and as a combination therapy.

Important! The active ingredient of Viferon suppositories for children is recombinant alpha2b-interferon.

The drug is sold in packs of ten suppositories, each of which has its own plastic container. Externally, the candles are oblong in shape with a thickening on one side. The color of the candles is white with a slight yellowish tint. The shelf life of Viferon candles is two years. It is recommended to store them in a cool place.

What are Viferon baby suppositories used for?

Viferon suppositories are prescribed to children when diagnosing the following diseases.

1. Acute respiratory viral infections. Most often they manifest themselves in the form of enterovirus infection and influenza. Children tolerate the disease quite hard, but still more harm apply fragile body complications. The diseases are accompanied by fever, muscle pain, headaches, and photophobia.
2. Pneumonia. Occurs when hitting the upper respiratory tract an infection that, without proper treatment, quickly descends, reaching the lungs. Pneumonia is not always easy to recognize; the disease is disguised as various pathologies. Common in preschool and younger children school age. Often the disease causes complications in the heart.
3. Meningitis. Defeat meninges virus, bacteria, fungi or protozoa. The disease is especially severe in children - vomiting begins, the temperature rises, photophobia, fever, and sometimes swelling of the extremities appear. Meningitis threatens with its consequences - mental retardation, toxic shock, and when untimely treatment Possible death.
4. Sepsis. Blood poisoning, in which the pathogen enters the blood and spreads throughout the body. The pathology is very difficult, with an increase in temperature and disruption of the circulatory, respiratory and nervous systems. Septic damage to the body is one of the leading causes of death in children.
5. Herpes. A viral infection of the body, in which the child’s body becomes covered with a herpetic rash. The disease indicates weak immunity. Herpes cannot be cured because the child is a carrier of the virus.
6. Chlamydia. Appears in a child from a sick mother and is transmitted during childbirth. Children with strong immunity cope with the disease, but for sick children, chlamydia develops into pneumonia, purulent conjunctivitis, rhinitis. Children become irritable, suffer from insomnia and seizures.
7. Cytomegalovirus. A disease similar to chlamydia. The main manifestations are muscle pain, lethargy, and increased body temperature.

It is also possible to use Viferon in children with liver cirrhosis due to hepatitis, however, the prognosis for the incidence of congenital cirrhosis in children is unfavorable, therefore in this case Viferon provides only symptomatic treatment.

In addition to the treatment of infectious diseases, Viferon suppositories can be used for prevention. This is especially true for influenza and colds, which children so often suffer from in the winter and spring, when the body’s defenses begin to weaken.

Mechanism of action of the drug

Viferon candles are rectal suppositories. They are placed in the baby's rectum, where under the influence of body temperature they become soft and are well absorbed by the rectal mucosa.

When the drug enters the child’s body, it begins to trigger several important processes for the baby:

• response intensifies immune system the child's body;
• cells (natural killer T-cells) are activated, producing antiviral protection for the body;
• the intensity of the inflammatory reaction decreases, as a result of which the child begins to feel much better;
• the recovery process starts cellular level.

Instructions for use of Viferon suppositories for children

Viferon suppositories can be used in children of all ages, starting from birth. The dosage of the drug is determined by the patient’s age and type of disease. You cannot use Viferon suppositories on your own, since each disease has its own application regimen. Only a doctor should prescribe the drug and formulate a dosage regimen.

Dosage of children's suppositories Viferon

Type of disease	Child's age	Dosage	Frequency of reception	Duration of treatment
Flu, ARVI, pneumonia.	Over 7 years old.	1 candle (500 thousand IU)	2 rubles/day. every 12 hours.	5 days
	Newborns, including premature babies (34-40 weeks) and children under 7 years of age.	1 candle (150 thousand IU)
Infectious diseases newborns and premature babies.	Newborns, including premature babies (more than 34 weeks).	1 candle (150 thousand IU)	2 times a day every 12 hours.	5 days courses from 1 to 3 depending on the type of infectious disease
	Newborns, including premature babies (less than 34 weeks).		3 r/day. every 8 hours.
Viral hepatitis B, C, D of a chronic nature.	Up to 6 months.	300 thousand - 500 thousand IU/day.	2 rubles/day. every 12 hours, for 10 days. Then the frequency of administration is reduced to 3 times a week, for a course of 6-12 months.	The duration of treatment and the number of courses are determined by the doctor individually
	From 6 months to a year.	500 thousand IU/day.
	From one year, but not older than 7 years.	3 million IU/day. per 1 m2 of body surface. The resulting daily dose is divided into 2 injections.
	Over 7 years old.	5 million IU/day. per 1 m2 of body surface The resulting daily dose is divided into 2 injections.

Contraindications

Viferon suppositories are well accepted by children, so there are practically no contraindications to their use. The only thing doctors always warn about is allergic reaction for the drug. Allergic manifestation – individual feature the child’s body, it does not appear in all children. Usually causes allergies coconut oil, which is part of the candles. Much less often, allergies occur to ascorbic acid, interferon and tocopherol. A negative reaction to the drug is manifested by a rash, most often localized on the face. Therefore, if the baby is allergic, then when using Viferon for the first time you need to monitor the condition of the skin of the cheeks, chin, and forehead. This is the most sensitive place where you can quickly notice rash spots. The percentage of such children is extremely small, but even in this case, Viferon is not discontinued, but continues to be used against the background of antihistamine therapy. In most cases, the rash from the drug disappeared on the third day, and positive effect for a child it was noted to be significantly higher.

Video on how to light a candle for a baby

Analogs of candles for children

If a child is allergic to Viferon, the doctor may recommend a replacement from the following list.

List of Viferon analogues

Most often, among analogues, they choose the drug Genferon, since it is in one price category with Viferon. The use of Genferon does not give this quick effect compared to Viferon. Kipferon is much more expensive, however chemical composition The drugs are somewhat different. In addition to alpha2b-interferon, Kipferon contains antibodies to many pathogens.

The domestic drug Viferon is one of the proteins of the human immune system - recombinant interferon alpha-2b. The drug has an immunomodulatory, antiproliferative (preventing cell proliferation) and antiviral effect. The scope of its application is quite extensive: these include viral and bacterial infections of a wide variety of etiologies and localizations. Infectious diseases most often plague a person throughout his life. life path. The fight against them is being carried out on all fronts using a wide variety of pharmacological “weapons”, the most serious of which are rightly considered to be antibiotics and chemotherapy. However, often antiviral and antibacterial therapy turns into attempts to kill a fly with a jackhammer: it is no secret that the same antibiotics, in addition to their deadly effect on microorganisms, undermine the body’s defenses and deplete its immune resources. In this regard, it was proposed to use interferon preparations as part of the complex treatment of viral and bacterial infections. These proteins from the family of cytokine mediators are an important link in the formation of immunity. A prominent representative of this group of drugs is Russian drug Viferon, produced in three dosage forms: ointment, gel and suppositories. The combination of ingredients included in Viferon brings a number of additional and by no means superfluous ingredients to its collection. pharmacological effects. Thus, antioxidants acting as auxiliary substances - tocopherol acetate and ascorbic acid (the latter is present only in suppositories) - increase the antiviral potential of interferon alpha-2b. With their active participation, the immunomodulatory effect of Viferon on T- and B-lymphocytes is enhanced, the concentration of secretory immunoglobulins (antibodies) of class A increases, the concentration of immunoglobulin E is normalized, and work is restored internal system interferon alpha-2b.

Alpha tocopherol and ascorbic acid themselves are capable of suppressing inflammation, stabilizing cell membranes and restoring damaged tissue. Thus, Viferon allows you to get by with smaller doses of antibacterial and hormonal drugs, and therefore reduce the likelihood of developing adverse reactions as part of antiviral and antibacterial therapy.

This is what is called the official program. Now - about the urgent matter, namely: Viferon, and this is no secret, is the subject of heated discussions in the medical and paramedical world. The fact is that a number of respected experts express objective doubts about its effectiveness, considering it almost a placebo. One of the arguments here is its instability in gastrointestinal tract, where it ends up when administered rectally. And the only way to keep the drug intact is subcutaneous or intramuscular injection, and, as is known, the manufacturer does not provide such dosage forms of Viferon. On the other hand, in MEDLINE databases (the world's largest database medical information, which unites about 75% of medical publications published on the globe) there are more than 40 mentions of Viferon. Yes, the main subject of research was not the domestic Viferon, but its pharmacologically active substance - interferon alpha-2. However, even with such an assumption, Viferon certainly cannot be called a dummy that does not have the slightest evidence of its effectiveness. In any case, while all these heated debates are going on, the drug itself feels very comfortable on pharmacy shelves and absolutely does not complain about the lack of attention from doctors and patients.

Pharmacology

Human preparation recombinant interferon alpha-2b. It has immunomodulatory, antiviral and antiproliferative properties. Suppresses the replication of RNA and DNA viruses. The immunomodulatory properties of interferon, such as increased phagocytic activity of macrophages and increased specific cytotoxicity of lymphocytes to target cells, determine its indirect antibacterial activity.

In the presence of antioxidants alpha-tocopherol acetate, citric and benzoic acids, the specific antiviral activity of interferon increases, its immunomodulatory effect increases, which makes it possible to increase the effectiveness of the body's own immune response to infectious agents.

The drug has a pronounced local immunomodulatory effect and helps to increase locally formed antibodies of the secretory IgA class, which prevent the fixation and proliferation of pathogenic microorganisms on the mucous membranes, which provides a preventive effect of the drug for the prevention of viral and other diseases.

The gel base ensures a prolonged effect of the drug. The antioxidants included in the dosage form (alpha-tocopherol acetate, citric and benzoic acids) have anti-inflammatory, membrane-stabilizing, regenerating properties, and also help preserve the biological activity of human recombinant interferon alpha-2b.

Pharmacokinetics

When applied externally and locally, systemic absorption of interferon is low.

Release form

Gel for external and local application in the form of a homogeneous, opaque, gel-like mass white with a grayish tint.

Excipients: α-tocopherol acetate - 55 mg, benzoic acid - 1.28 mg, sodium tetraborate decahydrate - 1.8 mg, methionine - 1.2 mg, citric acid monohydrate - 1 mg, sodium chloride - 4 mg, human serum albumin solution 10% - 20 mg, glycerol (distilled glycerol) - 20 mg, carmellose sodium - 20 mg, ethanol 95% - 55 mg, purified water - up to 1 g.

12 g - aluminum tubes (1) - cardboard packs.

Dosage

The drug is used externally and locally.

Included complex therapy ARVI, including influenza, long-term and frequent ARVI, incl. complicated bacterial infection: a strip of gel no more than 0.5 cm long is applied to the pre-dried surface of the nasal mucosa and/or to the surface of the tonsils 3-5 times a day using a spatula or a cotton swab/cotton swab. The course of treatment is 5 days; if necessary, the course can be extended.

Prevention of ARVI, including influenza: during the period of rising incidence, a strip of gel no more than 0.5 cm long is applied to the previously dried surface of the nasal mucosa and/or to the surface of the tonsils 2 times a day for 2-4 weeks.

As part of complex therapy for recurrent stenosing laryngotracheobronchitis: a strip of gel no more than 0.5 cm long is applied to the surface of the palatine tonsils using a spatula or a cotton swab/cotton swab in acute period diseases 5 times a day for 5-7 days, then 3 times a day for the next 3 weeks.

Prevention of recurrent stenosing laryngotracheobronchitis: a strip of gel no more than 0.5 cm long is applied to the surface of the tonsils using a spatula or a cotton swab/cotton swab 2 times a day for 3-4 weeks, courses are repeated 2 times a year.

As part of complex therapy for acute and chronic recurrent herpetic infections (at the first signs of the disease or during the period of warning signs): a strip of gel no more than 0.5 cm long is applied with a spatula or a cotton swab/cotton swab to a previously dried affected surface 3-5 times a day for 5-6 days, if necessary, the duration of the course is increased until clinical manifestations disappear.

As part of complex therapy for herpetic cervicitis: 1 ml of gel is applied with a cotton swab to the surface of the cervix, previously cleared of mucus, 2 times a day for 7 days; if necessary, the duration of the course can be increased to 14 days.

Rules for using the gel

The gel is applied to the mucous membrane of the nasal cavity after cleansing the nasal passages, and to the surface of the tonsils - 30 minutes after eating.

When applying the gel to tonsils Do not touch the tonsils with a cotton swab, but only with the gel; the gel flows down on its own along the surface of the tonsil.

When applying the gel to the cervix, you should first remove mucus and discharge from the vaginal vaults and cervix with a cotton or gauze swab.

When applying the gel to the affected areas of the skin and mucous membranes, after 30-40 minutes a thin film is formed, onto which the drug is again applied. If desired, the film can be peeled off or washed off with water before reapplying the drug.

The opened tube is stored in the refrigerator for no more than 2 months. Do not use the drug after the expiration date. The product is not suitable for use if the integrity of the packaging is damaged and the color has changed.

Overdose

Data on overdose of the drug Viferon ® are not provided.

Interaction

The drug goes well with all medicines, which are used in the treatment of the above diseases (antibiotics, chemotherapy, corticosteroids).

Side effects

Allergic reactions: very rare - skin rashes, itching.

Indications

• as part of complex therapy for ARVI, incl. influenza, frequent and prolonged acute respiratory viral infections, incl. complicated by bacterial infection;
• prevention of acute respiratory viral infections, including influenza;
• as part of complex therapy for recurrent stenotic laryngotracheobronchitis;
• prevention of recurrent stenosing laryngotracheobronchitis;
• as part of complex therapy for acute and exacerbations of chronic recurrent herpetic infections of the skin and mucous membranes, incl. urogenital form of herpetic infection;
• as part of complex therapy of herpetic cervicitis.

Contraindications

Hypersensitivity to the components of the drug.

Features of application

Use during pregnancy and breastfeeding

Pregnancy and lactation (breastfeeding) are not a contraindication for the use of the drug due to the very low absorption of the components.

During lactation, do not apply to the area of ​​the nipples and areola.

Use in children

Can be used in children according to indications.

The instructions for use indicate that Viferon suppositories are a means of stimulating the immune system and for the treatment of viral infections. The annotation states that the suppositories are safe for infants and pregnant women, but this does not mean that the medicine can be taken without medical supervision. Like other drugs, Viferon has contraindications and can cause harm to the body. What are the main characteristics of the medication and rules of use?

Blisters of 10 pieces contain slightly yellowish or white suppositories that contain the active substance - human recombinant interferon alpha-2b.

Pharmacological companies produce several versions of suppositories, differing in the amount of the active ingredient, which is measured in IU:

• 150000;
• 500000;
• 1000000;
• 3000000.

Different dosages allow you to purchase the drug necessary for treatment, taking into account the nature of the disease and the age of the person.

In addition to interferon, the medication contains excipients:

• confectionery fat;
• cocoa butter;
• sodium ascorbate;
• disodium edetate dihydrate;
• ascorbic acid;
• polysorbate;
• a-tocopherol acetate.

Additional components form a solid basis. After administration, the fats soften, interferon and additional components are released, which enhance the effect of the main substance.

Dosage form has a homogeneous structure, it can be divided into parts if a different dose is required.

For example, 1,500,000 IU is prescribed. You can purchase suppositories of 500,000 and 1,000,000 IU or buy suppositories containing 3,000,000 IU of interferon and divide in half. The second option will be more profitable financially.

After introducing the suppository, the hard base softens within 1-2 minutes and the active substance is absorbed through the mucous membrane.

After interferon enters the bloodstream, the following occurs:

• cells of the immune system are activated;
• the ability of viruses to reproduce is suppressed;
• the activity of pathogenic microorganisms is inhibited;
• lymphocyte activity increases;
• the intensity of the inflammatory process decreases;
• regeneration of damaged tissue is accelerated.

Lymphocytes and macrophages (cells responsible for the immune response) more actively recognize and destroy viruses that have entered the body.

The action of interferon is similar to the body's immune response. But the immune system fully activates its response forces only 3-5 days after the virus enters the body. With the help of Viferon suppositories, viruses are eliminated almost immediately, so the drug can be used not only for treatment, but also to strengthen the body’s immune forces during seasonal epidemics of ARVI or influenza.

If we consider what Viferon helps with, then after studying the effect on the body it becomes clear that the medication stimulates the immune system and helps destroy viruses.

Indications for use are:

• frequent colds;
• viral infections;
• severe course diseases caused bacterial microflora(addition to main therapy);
• chronic hepatitis;
• non-infectious inflammatory processes in the liver;
• enteroviral diseases;
• meningitis;
• sepsis;
• intrauterine infection in newborns;
• diseases transmitted through sexual contact (in women, suppositories are inserted deep into the vagina);
• herpetic rashes;
• prevention of viral infections.

The immunomodulator interferon helps reduce doses of antibacterial or anti-inflammatory drugs and speed up the patient’s recovery process.

This reduces the risk of possible complications and reduces negative impact medications taken on the mucous membrane digestive tract.

The prohibition on the use of Viferon suppositories is:

• individual intolerance to components (main and auxiliary);
• kidney pathologies accompanied by functional failure;
• pronounced violation liver functions;
• cardiovascular diseases;
• abnormalities in the functioning of the thyroid gland.

Caution should be exercised when treating with medication if a person has the following pathologies:

• atopic dermatitis or eczema;
• melanoma;
• neutropenia;
• thrombopenia;
• diseases caused autoimmune processes;
• diseases that require the use of tranquilizers.

The only absolute contraindication is individual intolerance to the components.

For the listed diseases, treatment with Viferon under the supervision of a doctor is allowed in order to promptly prevent possible complications.

Features of treatment for pregnant and lactating women

The description of the drug states the following:

• penetrates the hemoplacental barrier;
• excreted in breast milk.

If you go to a forum dedicated to discussing the use and breastfeeding, then you can see different opinions. Some women are sure that the medicine is harmful for the baby, while their opponents insist that the immune system needs to be strengthened in utero. Both sides are wrong.

Indeed, additional effects on the child’s immune system are undesirable, but human recombinant interferon alpha-2b is similar to human and does not harm the child.

During pregnancy and lactation it is allowed to be treated with Viferon under medical supervision. The only exception is the first 2 weeks of gestation (first trimester) - the effect of the drug on the embryo was not carried out during this period.

The dose is selected taking into account the age and nature of the disease.

When treating viral infections:

1. Premature infants born before 34 weeks of gestation - 150,000 IU. Suppositories are administered three times a day every 8 hours.
2. Infants born after 34 weeks of gestation and children under 7 years old are prescribed 250,000 IU/day. The dose is divided into 2 doses and administered at intervals of 12 hours.
3. A child over 7 years old and an adult are prescribed 500 thousand IU twice a day.

Treatment is carried out for 5 days. If necessary, course antiviral therapy repeat after a five-day break.

The dosage when using suppositories with Viferon as an adjuvant in the treatment of bacterial infections is the same as when viral diseases.

The number of treatment courses depends on the nature of the disease:

• sepsis - 2-3;
• meningitis - 1-2;
• sexual infections - 2-3;
• herpes - 2.

If necessary, 4 courses of treatment can be carried out.

Herpetic infection of any form:

• adults - 1 million IU twice a day for 10 days;
• pregnant women - 500,000 IU 2 times a day for 10 days.

Therapy for viral hepatitis:

• from birth to 6 months - 250-500 thousand IU per day;
• from 6 months to a year - 500 thousand IU/day;
• adults - 3,000,000 IU 2 times a day.

For a child older than one year, the dosage is calculated based on the ratio of 3 million IU per m2 of body area. Total area is calculated using a special table, including the ratio of weight, height and age.

Daily dose for children will be:

• 1-7 years - 3,000,000/m2;
• over 7 years - 5,000,000/m2.

The treatment regimen for hepatitis is as follows:

• 10 days daily twice a day;
• after a ten-day period for 6-12 months, suppositories are administered every other day.

The duration of therapy for hepatitis is determined individually, taking into account test data.

Uroginetal infections are treated by administering suppositories of 500,000 IU twice a day. During pregnancy, the same dosage is indicated.

Algorithm for introducing the Viferon candle into anus children the following:

• wash your hands;
• put the child on his side with his knees pulled up to his stomach;
• carefully open the blister and remove the suppository;
• dip the candle in warm water (to facilitate insertion);
• carefully insert the candle into the anus;
• Squeeze your buttocks with your hand and hold for 1-2 minutes.

An adult is given suppositories according to the same scheme.

If a woman is prescribed vaginal use of the drug, then the suppository must be pushed as deep as possible to obtain the necessary therapeutic effect. But because anatomical features organ, a woman is often asked to replace suppositories with inserting tampons into the vagina with ointment containing similar composition.

This form of release, such as candles, reduces the likelihood of developing negative reactions due to the fact that there are no antibodies in the colon.

IN in rare cases patients develop:

• headaches;
• hives;
• itching or burning in the area anus;
• decreased appetite;
• nausea and sometimes vomiting;
• stool disorder;
• abdominal discomfort;
• chills;
• weakness.

Signs of deterioration in health that appear disappear on their own 2-3 days after stopping the medication. But in the future, Viferon suppositories cannot be used for the treatment of diseases.

If an overdose of the drug is accompanied by a deterioration in health, then you need to take a three-day break so that the symptoms that appear disappear and consult a doctor about continuing Viferon therapy.

When prescribing Viferon for adults, doctors warn that during the course of treatment it is necessary to abstain from alcohol. Alcohol consumption reduces the activity of interferon, which means that the therapy will be less effective.

Before prescribing a medication, a blood test is performed to determine:

• creatinine;
• calcium;
• electrolytes;
• leukocyte formula.

These indicators are necessary for selecting the dosage and monitoring the quality of therapy.

If you have the diseases specified in relative contraindications, an adult is prescribed a half dose of 125-250 thousand IU twice a day. If the medication is well tolerated and there is no negative effects the dosage is gradually increased to that recommended in the instructions.

Viferon does not affect neuropsychic reactions, and its use is allowed to drive vehicles and operate moving mechanisms.

With frequent and uncontrolled use of the medicine, addiction to interferon occurs and immunity does not stimulate.

Interaction with other drugs

If the patient is taking antibiotics to treat bacterial infections, the administration of Viferon enhances the antibacterial effect. This is taken into account when prescribing complex therapy.

Taking antidepressants together with the use of suppositories increases the risk of side effects.

There is no data on the interaction of Viferon with other medications. The introduction of suppositories does not affect the well-being of a person taking pills for hypertension, atherosclerosis, etc.

If you watch the video where Dr. Komarovsky talks about Viferon children's suppositories, we can conclude that the drug is safe for the baby's body, but practically useless for prevention and treatment. A well-known pediatrician believes that candles calm parents more than help cure the child.

Some mothers and grandmothers agree with this opinion, others assure high efficiency medicine. Let's get acquainted with the positive and neutral reviews parents:

Our Marinochka was six months old when she was diagnosed with ARVI. My daughter had a high fever and a runny nose. The pediatrician prescribed Viferon and advised me to buy suppositories. Very convenient. Marinka always spits out the medicine, but she tolerated the candle in her butt well. We were treated for 5 days, using Viferon 2 times a day, and the package was enough for the entire course. On the 3rd day the fever went away, and then the snot disappeared.

Svetlana

My mother believes that Viferon helps most with colds, and puts candles on her one-year-old grandson. I watched a program with Dr. Komarovsky, where he talked about the harmlessness of Viferon for children and I don’t argue. But I know that suppositories won’t help, and if I don’t start treating my son right away, he will be sick for a long time.

My wife and daughter went to the pediatrician, and the doctor prescribed Viferon for a cold. Neighbors with small children spoke well of the suppositories, but the medicine did not help our child. On the 3rd day the child still had a fever, a runny nose and cough appeared. I had to call a doctor to prescribe another treatment.

I often hear that Viferon cannot cure a cold, but for my daughter it is first aid. As soon as the temperature appears, I immediately light candles. I know that you can’t bet often, and it’s not necessary. It seems to me that after I started using Viferon, my daughter began to get acute respiratory infections less often.

After reading the opinions of parents, let's see what adults who took the medication say:

We have an ARVI epidemic at work, everyone is sneezing and coughing. I read on the Internet about Viferon tablets, but they were not available in the pharmacy. I had to take candles. For 5 days I lit candles in the morning and evening, until the packaging ran out. I don’t know if Viferon helped or it’s the same for me strong immunity, but I managed not to catch a cold from my colleagues.

She was treated for pneumonia at the pulmonology department. Along with antibiotics, Viferon suppositories were prescribed. Before putting the candles on, I read the instructions and found out that the medicine stimulates the immune system and together with it, antibiotics work better. It's probably true. My roommate and I were admitted to the hospital at the same time and with the same diagnosis, but I recovered faster.

Anonymous (user has hidden his name)

I was treated with Viferon for mycoplasmosis and put suppositories in the vagina. It didn’t help me, control tests showed no improvement, and I was prescribed another therapy.

As can be seen from the reviews, in some cases the drug helps, but in others it does not bring relief from the disease. It is impossible to determine which group the patient will be in, but if not serious illnesses, then the use of the drug is safe for health.

Close analogues

Viferon is almost always available in the pharmacy, but if the medicine is not on sale, then medicines that have similar action on the body.

Genferon

Combined remedy, which includes:

• taurine;
• interferon.

Genferon increases immune strength and suppresses the activity of viruses.

Release form: drops, spray and suppositories for vaginal and rectal administration.

It is not allowed for pregnant women in the 1st trimester, and drops can be given to infants only after 29 days of life.

The drug contains 2 active components:

• interferon;
• purified immunoglobulin identical to human.

In its action, Kipferon is close to Viferon.

You can buy vaginal and rectal suppositories at the pharmacy.

Prohibited for pregnant and lactating women.

Grippferon

Contains only interferon and is considered a substitute for Viferon.

It is available only in the form of a spray, and this is not very convenient for the treatment of certain diseases.

Interferon solution

Used for topical use only:

• nasal drops;
• inhalation through a nebulizer.

Helps the immune system destroy viruses that have entered the body.

It is important to remember that the dosage of analogues is different; if Viferon is replaced with another drug, you need to consult a doctor about a single and daily dose.

The drug is valid for 2 years from the date of manufacture (the date is stamped on the blister or indicated on the packaging box).

But if storage conditions are not met, the medicine loses its activity. To save medicinal properties interferon, the following conditions must be observed:

1. Do not freeze. The temperature should be at least +2°C.
2. Do not overheat. Influence high temperatures not only makes suppositories soft and uncomfortable to use, but can also disrupt the homogeneous structure of the drug.

The optimal mode for storing candles is from +2 to +10°C. This can be achieved by placing the medicine package on the refrigerator door.

Well, you should remember that medications should be inaccessible to children. Despite the fact that Viferon suppositories do not have a pleasant taste, curious children can put suppositories in their mouths and swallow them, and this will cause digestive upset.

A prescription is not required to purchase Viferon. The medicine can be purchased in 2 ways:

• visit a pharmacy;
• order on the manufacturer's website.

Although the medication is available without a prescription, you should not self-medicate by trying to cure a cold on your own.

The main danger is that a person does not always know that he has diseases that are a contraindication for treatment, and this can cause complications.

Cost of suppositories

Price depends on content active substance:

• 1 million IU - 550 rubles;
• 500 thousand IU - 400 rubles;
• 150 thousand IU - 150 rub.

The price is indicated for a blister containing 10 pieces, which can be ordered on the manufacturer’s website.

The price will be higher at the pharmacy.

Its increase will be affected by:

• trade markup;
• location of the pharmacy (on a quiet street or near busy traffic);
• region:
• brand.

Ordering online will be cheaper, but you will need to wait a few days. For those who are undergoing a long course of treatment (for hepatitis) or often take medicine for colds and flu, it is recommended to order the drug in advance and store it in the refrigerator.

Most doctors speak well of Viferon suppositories, noting good tolerability medication and effectiveness during antiviral or complex antibacterial therapy.

Active ingredient

Interferon alfa-2b human recombinant (interferon alfa-2b)

Release form, composition and packaging

◊ Rectal suppositories

Excipients: α-tocopherol acetate - 55 mg, - 5.4 mg, sodium ascorbate - 10.8 mg, disodium edetate dihydrate - 100 mcg, polysorbate 80 - 100 mcg, cocoa butter base and confectionery fat - up to 1 g.

◊ Rectal suppositories white with a yellowish tint, bullet-shaped, uniform consistency; heterogeneity of color in the form of marbling and the presence of a funnel-shaped depression on the longitudinal section are allowed; suppository diameter no more than 10 mm.

Excipients: α-tocopherol acetate - 55 mg, ascorbic acid - 8.1 mg, sodium ascorbate - 16.2 mg, disodium edetate dihydrate - 100 mcg, polysorbate 80 - 100 mcg, base cocoa butter and confectionery fat - up to 1 g.

10 pcs. - contour cellular packaging (1) - cardboard packs.

Pharmacological action

Human recombinant interferon alpha-2b has immunomodulatory, antiproliferative properties, suppresses the replication of RNA and DNA viruses. The immunomodulatory properties of interferon alpha-2b, such as increased phagocytic activity of macrophages, increased specific cytotoxicity of lymphocytes to target cells, determine its indirect antibacterial activity.

In the presence of ascorbic acid, the specific antiviral activity of interferon alpha-2b increases, its immunomodulatory effect is enhanced, which makes it possible to increase the effectiveness of the body’s own immune response to pathogenic microorganisms. When using the drug, the level increases secretory class And, the level of immunoglobulin E is normalized, the functioning of the endogenous interferon alpha-2b system is restored. Ascorbic acid and alpha-tocopherol acetate, being highly active antioxidants, have anti-inflammatory, membrane stabilizing, and regenerating properties. It has been established that when using the drug Viferon there are no side effects, which occur during parenteral administration of interferon alfa-2b preparations, antibodies are not formed that neutralize the antiviral activity of interferon alfa-2b. The use of the drug Viferon as part of complex therapy can reduce therapeutic doses antibacterial and hormonal drugs, as well as reduce the toxic effects of this therapy.

Cocoa butter contains phospholipids, which make it possible not to use synthetic toxic emulsifiers in production, but the presence of polyunsaturated fatty acids facilitates the administration and dissolution of the drug.

Indications

- acute respiratory viral infections, including influenza, incl. complicated by bacterial infection, pneumonia (bacterial, viral, chlamydial) in children and adults as part of complex therapy;

— infectious and inflammatory diseases of newborns, incl. premature babies, such as meningitis (bacterial, viral), sepsis, intrauterine infection(chlamydia, herpes, cytomegalovirus infection, enterovirus infection, candidiasis, incl. visceral, mycoplasmosis), as part of complex therapy;

- infectious and inflammatory diseases of the urogenital tract (chlamydia, cytomegalovirus infection, ureaplasmosis, trichomoniasis, gardnerellosis, papillomavirus infection, bacterial vaginosis, recurrent vaginal candidiasis, mycoplasmosis) in adults as part of complex therapy;

- primary or recurrent herpetic infection of the skin and mucous membranes, localized form, mild and moderate course, incl. urogenital form in adults.

Contraindications

— increased sensitivity to any of the components of the drug.

Dosage

The drug is administered rectally.

1 suppository contains human recombinant interferon alpha-2b as an active substance in the indicated dosages (150,000 IU, 500,000 IU, 1,000,000 IU, 3,000,000 IU).

Acute respiratory viral infections, including influenza, incl. complicated by bacterial infection, pneumonia (bacterial, viral, chlamydial) in children and adults as part of complex therapy

Recommended dose for adults, including pregnant women and children over 7 years old- Viferon 500,000 IU, 1 suppository 2 times a day every 12 hours every day for 5 days. By clinical indications therapy can be continued.

Children under 7 years old, incl. newborns and premature infants with a gestational age of more than 34 weeks, Viferon 150,000 IU is prescribed, 1 suppository 2 times a day every 12 hours every day for 5 days. According to clinical indications, therapy can be continued. The break between courses is 5 days.

Viferon 150,000 IU is prescribed, 1 suppository 3 times a day every 8 hours every day for 5 days. According to clinical indications, therapy can be continued. The break between courses is 5 days.

Infectious and inflammatory diseases of newborns, incl. premature babies, such as meningitis (bacterial, viral), sepsis, intrauterine infection (chlamydia, herpes, cytomegalovirus infection, enterovirus infection, candidiasis, including visceral, mycoplasmosis) as part of complex therapy

Recommended dose for newborn children, incl. premature babies with a gestational age of more than 34 weeks, - Viferon 150,000 IU daily, 1 suppository 2 times a day every 12 hours. The course of treatment is 5 days.

Premature newborns with a gestational age of less than 34 weeks Viferon 150,000 IU is prescribed daily, 1 suppository 3 times a day every 8 hours. The course of treatment is 5 days.

Recommended number of courses for various infectious and inflammatory diseases: sepsis- 2-3 courses, meningitis- 1-2 courses, herpetic infection- 2 courses, enterovirus infection- 1-2 courses, cytomegalovirus infection-2-3 courses, mycoplasmosis, candidiasis, incl. visceral- 2-3 courses. The break between courses is 5 days. According to clinical indications, therapy can be continued.

Chronic viral hepatitis B, C, D in children and adults as part of complex therapy, incl. in combination with the use of plasmapheresis and hemosorption for chronic viral hepatitis pronounced activity, complicated by cirrhosis of the liver

Recommended dose for adults- Viferon 3,000,000 IU, 1 suppository 2 times a day every 12 hours every day for 10 days, then three times a week every other day for 6-12 months. The duration of treatment is determined clinical effectiveness and laboratory indicators.

Children aged 1 to 7 years recommended 3,000,000 IU per 1 m 2 body surface area/day.

The drug is used 2 times a day after 12 hours for the first 10 days daily, then three times a week every other day for 6-12 months. The duration of treatment is determined by clinical effectiveness and laboratory parameters.

The daily dose of the drug for each patient is calculated by multiplying the recommended dose for a given age by the body surface area calculated using the nomogram for calculating body surface area by height and weight according to Garford, Terry and Rourke. The calculation of a single dose is carried out by dividing the calculated daily dose into 2 administrations, the resulting value is rounded up to the dosage of the suppository.

At chronic viral hepatitis of pronounced activity And liver cirrhosis before plasmapheresis and/or hemosorption is prescribed children under 7 years of age Viferon 150,000 ME, children over 7 years old- Viferon 500,000 IU, 1 suppository 2 times a day every 12 hours every day for 14 days.

Infectious and inflammatory diseases of the urogenital tract (chlamydia, cytomegalovirus infection, ureaplasmosis, trichomoniasis, gardnerellosis, human papillomavirus infection, bacterial vaginosis, recurrent vaginal candidiasis, mycoplasmosis) in adults, including pregnant women as part of complex therapy

Pregnant women from the second trimester of pregnancy (starting from the 14th week of gestation) Viferon 500,000 IU is prescribed, 1 suppository 2 times a day every 12 hours every day for 10 days, then 1 suppository 2 times a day every 12 hours every fourth day for 10 days. Then every 4 weeks until delivery - Viferon 150,000 IU, 1 suppository 2 times a day after 12 hours every day for 5 days. If necessary, Viferon 500,000 IU is prescribed before delivery (from the 38th week of gestation), 1 suppository 2 times a day after 12 hours every day for 10 days.

Primary or recurrent herpetic infection of the skin and mucous membranes, localized form, mild to moderate course, incl. urogenital form in adults, including pregnant women

Recommended dose for adults- Viferon 1,000,000 IU, 1 suppository 2 times a day every 12 hours every day for 10 days or more for recurrent infection. According to clinical indications, therapy can be continued. It is recommended to begin treatment immediately when the first signs of damage to the skin and mucous membranes (itching, burning, redness) appear. During treatment recurrent herpes It is advisable to begin treatment in the prodromal period or at the very beginning of signs of relapse.

When colds overwhelm our body, the immune system needs help. This is especially true for children whose protective functions of the body are not yet fully formed.

In this case, pediatricians prescribe antiviral drugs, which can not only put the baby on his feet, eliminating symptoms and relieving fever, but also strengthen the immune system.

Composition, active substance, description, release form

The active ingredient is interferon. The product is available in the form of rectal suppositories oblong shape of a white-gray hue. On the cut of the suppositories you can see a small depression. The diameter of the candles is 10 mm.

Main components of Viferon 150000:

• polysorbate;
• confectionery fat;
• sodium ascorbate;
• α-tocopherol acetate;
• cocoa butter;
• ascorbic acid;
• benzocaine;
• edetate disodium.

These substances are safe for children and toddlers infancy, newborns and premature babies.

In pharmacies you can find the drug in the form of ointments and gels., there are also suppositories in dosages from 150,000 to 3,000,000 IU. For children it is better to take suppositories with minimum dose interferon.

Find out on our website everything about the well-known absorbent drug -!

About the antibiotic broad action Augmentin 125 mg and suspension dosage for children in at different ages find out at .

Indications

Candles Viferon 150000 – a drug that has an immunostimulating and antiviral effect . The drug, in combination with other drugs, fights all diseases of an infectious and inflammatory nature.

Suppositories can be used at any age, starting from the first days of life. Medicine is often prescribed for premature babies to stimulate protective functions body.

Suppositories are used in the treatment of diseases caused by bacteria, and when:

IN complex treatment Viferon 150000 is also prescribed for hepatitis types B, C, D, and hepatitis viral origin with simultaneous liver cirrhosis.

Contraindications

Viferon 150000 is one of the safest drugs for children (including premature babies).

In rare cases, a reaction may develop to the components of the suppository in the form of an allergy. There may be redness and rash on the skin, which can cause unbearable itching.

If such symptoms occur, use of the drug should be stopped.. There is no need to treat allergies, since all accompanying symptoms will leave the baby 3 days after stopping the use of Viferon.

The use of suppositories may cause swelling of the face, lower and upper limbs. This is given close attention due to the likelihood of angioedema.

The mother should monitor her baby for 2 hours after using suppositories.

If the baby has difficulty swallowing and his tongue is swollen, an ambulance is urgently called, since there is a possibility of swelling of the larynx.

How does the drug work, how long does it take to see the effect?

Viferon 150000 – complex medicine, the effect of which is achieved thanks to active ingredients half an hour after use. The drug has antiviral and immunostimulating effects.

Ascorbic acid and alpha-tocopherol acetate increase interferon's ability to resist viruses and microbes, increase its immunostimulating effect, i.e. the ability of the immune system to fight back microbes that have entered the body. These components are antioxidants that can have an anti-inflammatory and restorative effect on the body.

Features of taking cough medicine in.

Dosage by age

Suppositories are administered rectally only. Suppositories are used in the complex treatment of viral and infectious diseases in children. For newborn and premature babies, Viferon is prescribed at a dosage of 150,000.

The drug is administered in the morning and evening. The interval should be 12 hours. The course of therapy lasts no more than a week. If the baby feels better after just a few days of treatment, you can stop using Viferon.

Serious diseases are treated in several courses. With enterovirus, herpetic infections Viferon therapy is 5 days. After this, an equal break is taken, then the treatment is repeated again.

For sepsis, cytomegalovirus infection, mycoplasmosis, candidiasis, such courses should be at least 3.

At chronic hepatitis with the presence of liver cirrhosis, before the plasmaphoresis procedure ( modern technique cleansing the body at the cellular level) Viferon 150000 is also prescribed. Such treatment will quickly put the patient on his feet and strengthen him. immune functions body. The product must be taken every 12 hours or before the procedure.

For viral hepatitis of viral origin, children under 6 months of age are prescribed suppositories in a dosage of 300,000-500,000 IU. From 6 to 12 months – 500,000 IU.

For children from one year to 7 years and above, the dosage is prescribed depending on body weight and can be 3,000,000 IU. Those over 14 years of age should take 5,000,000 IU. The daily dose is designed for 3-4 doses.

How to use

Before using suppositories anal passage It is better to lubricate with baby cream or Vaseline. For ease of insertion, the child should be placed on his side and his knees raised.

In this video you will learn in detail how to properly light a candle for a child: