Hello!

The topic today is serious, necessary and controversial. Tropicamide eye drops cause people to suffer poor eyesight and the wars over the usefulness/necessity of Tropicamide do not subside....and, most likely, will never subside. I will broadcast from my bell tower.

A couple of years ago I had to change my favorite doctor to a bespectacled woman who insisted that with my -0.5 (at that time) I urgently needed glasses. She assured me that right now, instantly, this structure needs to be mounted on the nose, Otherwise I simply won’t survive.

With a kind word, for several years in a row I remember the old doctor, who said at every appointment that once put on glasses - there is no turning back. I honestly believe this. Now I can say that if I had been unlucky to meet the first doctor, I would have easily succumbed to provocation from the second.

The first appointment with the new doctor ended in a semi-scandal and I flew out of the office with the words “I’ll come in a month, you’ll see everything for yourself.” To which the doctor snorted displeasedly.

In order not to bore the reader, I will say:

“Yes, a month later I came and saw everything, even the tiniest letters on the board”

I saw it, and didn’t memorize it. The expression on the evil one's face as she adjusted her glasses on her nose was something you had to see. For our next meeting, which will not take place soon, I’m thinking of selling front row tickets.

So as not to mislead you - Tropicamide eye drops are not the eighth wonder of the world, and not even the ninth. My vision is restored not only thanks to them. There are no magic pills.

Initial data:

The right eye sees perfectly, the left one is acting up. The readings have not dropped below -1 (myopia) for five years. Under certain conditions, visual acuity reaches 100%, however stress and overexertion affect my vision.

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Eye drops Tropicamide 1%

Average cost of 10ml a bottle costs 120 - 130 rubles.
According to the instructions, it is supposed to be used within a month from the moment of opening. I asked the doctor Is it possible longer? The answer to me was this - a short period is set due to bacteria getting into the bottle, which was initially sterile. And one month is optimal safe time use of any eye drops.

I confess honestly - I use it after opening it longer than a month since I usually take drops for two weeks, take a break for a week and use the drops for another two weeks. Over the course of several years, my forgetfulness led me to this particular scheme, it’s more convenient for me. It is usually recommended to use a course per month.

Dispensing Tropicamide eye drops from pharmacies: In an ideal world, drops are sold only with a prescription, although some pharmacists sell them without it. One day I had to return to the Eye Center because I forgot to put another stamp on the prescription. The pharmacist was adamant, we had to go. The recipe was not withdrawn; several “batches” of drops were purchased from one recipe.

The difference between 0.5% and 1% in active substance(tropicamide) per ml. 5mg and 10mg respectively. Children are more often prescribed 0.5%, adults “depending on the situation”. I didn’t notice much difference between the two dosages of Tropicamide. The junkies know the difference better) Speaking of them...

My bad reputation Tropicamide drops were obtained precisely because of the main active ingredient - Tropicamide, which is used with pleasure by drug addicts. Normal people They drop them into the eyes and they are injected into a vein. It makes absolutely no difference to me why some Petya is being bullied.

By taking this drug, neither you nor your child will get hooked on it... I’ve seen so many crazy poems from crazy mothers on various forums.

◢ Separately, it is necessary to highlight contraindications:

hypersensitivity, glaucoma, intraocular hypertension (increased intraocular pressure). Tropicamide eye drops increase intraocular pressure.

◢ And side effects:

local reactions: allergies, increased intraocular pressure, photophobia, decreased visual acuity.

systemic side effects: headache, psychotic reactions, tachycardia, decreased blood pressure, hyperthermia, dry mouth, dysuria (impaired urination), convulsions.

You can’t argue with contraindications, but you can argue about side effects with saliva. One thing is certain - everyone will have photophobia for some time (1-3 hours) due to pupil dilation. We are all different, we all have different health. I did not experience any side effects other than photosensitivity.

◢ How I use it:

I turn off the lights in the room and leave the diffused light of the lamp behind me. I drop Tropicamide, close my eyes, turn off the lamp and go straight to bed. The drops hurt/sting your eyes for the first thirty seconds...it’s impossible to describe the sensations. I noticed that the less tired the eyes are, the less discomfort after instillation. After just a few minutes, the pupils dilate and it becomes uncomfortable to look at objects that are closer than arm's length.

At the end of the application, my eyes noticeably relax, it becomes much more comfortable for me to “look and see”... Maximum results are achieved with minimal eye strain during the course.. I spend less time on the computer, as much as possible, and go out for a walk more often and “look into the distance.”

Conclusion: I can’t give five stars to a prescription drug...it’s very strange to recommend such drops, but you have to choose something, so if your doctor prescribes you Tropicamide, don’t be afraid, there’s nothing wrong with taking it if your myopia is not caused by increased intraocular pressure [I repeat once again that Tropicamide increases it].

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Thank you for spending time with me,

Photo of the drug

Latin name: Tropicamidum

ATX code: S01FA06

Active substance: Tropicamide

Manufacturer: Warsaw Pharmaceutical Works Polfa (Poland), C.O. Rompharm Company S.R.L. (Romania), Promed Exports (India)

Description is valid on: 23.10.17

Tropicamide is an m-cholinergic receptor blocker intended for topical use in ophthalmology. Used for examinations of the fundus and lens of the eye, as well as for treatment inflammatory diseases eye. In addition, drops are used to prepare the eyes for laser and surgical operations.

Active substance

Tropicamide.

Release form and composition

Available in the form of eye drops in 5 ml dropper bottles.

Indications for use

Used when carrying out diagnostic examinations the fundus and lens of the eye, as well as during the study of refraction, when there is a need to develop paralysis of accommodation.

Actively used in the treatment of inflammatory eye diseases, in surgical practice and as prophylactic, preventing the appearance of synechiae in the postoperative period.

Contraindications

Contraindicated in case of angle-closure and mixed glaucoma, as well as in case of hypersensitivity to its components. It is not advisable to use these eye drops during pregnancy and lactation period, but still possible if expected therapeutic effect exceeds potential danger for the development of the child.

Instructions for use Tropicamide (method and dosage)

The drug is intended for conjunctival administration.

Eye drops 0.5%. Used for diagnostic pupil dilation. The drug is instilled in 1-3 drops over 10 minutes. When instilled three times, an ophthalmoscopy is performed after 10 minutes.

To determine refraction, drops are instilled 6 times with a break of 6-12 minutes.

When used in medicinal purposes instilled up to 6 times a day.

Eye drops 1%. For the effect of cycloplegia when studying refraction, the solution is instilled in 1 - 2 drops. The procedure is repeated after 5 minutes. If the patient has not been examined for 20 - 25 minutes, an additional drop of 1 drop is instilled to prolong mydriasis.

Side effects

The use of the drug may cause the following side effects:

• From the central nervous system: headaches, psychotic symptoms, behavioral disorders (especially in adolescents and children).
• From the organ of vision: photophobia, increased intraocular pressure or impaired visual acuity.
• From the outside of cardio-vascular system: tachycardia (in adults), symptoms of respiratory and circulatory failure.

Other consequences may include dry mouth and allergic reactions.

When taking the drug intravenously, side effects such as psychomotor agitation, confusion and hallucinations. Intravenous use can lead to severe drug dependence on the drug.

Overdose

If the drug is used haphazardly or administered intravenously, an overdose may occur. Antidotes in this case are benzodiazepines, beta-blockers and physostigmine salicylate.

Analogs

Analogs by ATX code: Midriaticum Shtuln PU, Midriacil, Midrum.

Do not decide to change the drug on your own; consult your doctor.

pharmachologic effect

Tropicamide eye drops have a pronounced mydriatic and anticholinergic effect. The drug causes paralysis of accommodation, dilates the pupil and blocks m-cholinergic receptors.

The drug leads to less paralysis of accommodation compared to atropine, with virtually no effect on intraocular pressure.

The effect of the drug develops 5 to 10 minutes after instillation. When using a 0.5% solution, pupil dilation persists for an hour, and when instilling a 1% solution - up to two hours. Paralysis of accommodation after using 1% drops persists for half an hour.

special instructions

• Before using Tropicamide, the doctor should warn the patient about possible temporary visual disturbances and photophobia.
• Usage contact lenses during treatment with the drug may lead to undesirable consequences. During treatment with the drug, patients should refrain from driving and engaging in potentially hazardous activities.
• It is strictly prohibited to use the drug for non-medical purposes. The consequences of Tropicamide when administered by injection are extremely dangerous: a sharp drop in hemoglobin levels, yellowing of the skin, epileptic seizures and irreversible vision loss. In addition, the drug used intravenously leads to the following consequences: pain in the muscles and internal organs, memory loss, heart disease, tissue detachment from the skeleton, madness and brain degradation.

During pregnancy and breastfeeding

Use during pregnancy is permissible only in cases where the intended benefit to the mother outweighs the potential risk to the fetus.

Should be used with caution during lactation.

In childhood

U infants and children under 6 years of age are required to use only 0.5% eye drops.

Before using the drug for diagnostic purposes in children, the accompanying person should be warned about temporary photophobia and visual impairment.

In old age

Information is absent.

Drug interactions

• The use of Tropicamide in combination with quinidine, procainamide, anticholinergics, phenothiazines, MAO inhibitors, benzodiazepines, histamine H1 receptor blockers, tricyclic antidepressants and antipsychotics mutually enhances pharmachologic effect each other.
• Paralysis of accommodation caused by Tropicamide increases when it is used in combination with sympathomimetic drugs and decreases when joint reception with parasympathomimetic agents.
• Combined use with nitrates, nitrites, disopyramide, haloperidol, corticosteroids and alkalizing agents for angle-closure glaucoma can lead to an increase in intraocular pressure.

From October 1, 2015 medicinal product tropicamide is included in the list of drugs subject to registration. For what reason do they not give more? buy tropicamide without a prescription, after all, it would seem a harmless medicine to dilate the pupil. What could cause such serious security measures in terms of its implementation? So let's find out.

What is tropicamide: instructions

Reading the instructions for using tropicamide, we stop at an overdose and side effects and contraindications.

• Contraindications: glaucoma, allergic reactions.
• Side effects: burning sensation, fuzzy visual perception, attacks of glaucoma, photophobia, etc.
• Overdose: When local application if prescribed by a doctor, an overdose is unlikely - the answer to most instructions for the use of tropicamide.

Nothing life-threatening, everything is absolutely safe. Yes, it seems safer at first glance activated carbon. But looking into the dark corners of the Internet and surfing websites for drug addicts, I found out some interesting information...

Those who are used to getting pleasure from taking various drugs are tirelessly looking for something new. Often they have to re-read a lot pharmacological reference books, in which they find medications containing drugs. One of the medications that drug addicts misuse is tropicamide.
This medicine is an M-choline blocker. This group Medicines get their name from the function they perform in the human body. These substances prevent the transmission nerve impulses, passing through the CNS receptors called M-cholinergic receptors.

How to use Tropicamide in ophthalmology and why

This medicine is available in the form of drops. And these drops are put into the eyes. Tropicamide blocks nerve receptors that are located in the eyeball, thereby dilating the pupil of the eye. This property of tropicamide is used by ophthalmologists. The fact is that when the patient's pupils are dilated, this allows them to clearly see the fundus of the eye. This medicine is also an anti-inflammatory agent, and it effectively soothes the eyes during various inflammatory processes that may occur in them.
But the properties of tropicamide are not limited to its effect on certain receptors nervous system, located in the human eye.

Tropicamide: use as a drug

Initially, drug addicts used tropicamide to hide the constriction of the pupils of the eyes, which is characteristic symptom when consuming most narcotic substances made from opium.
However, over time, they were able to discover one more property of this drug. When using tropicamide, people under the influence of a narcotic potion felt its effects more strongly. Thus, they realized that this substance enhances the effect that drugs have on the human body. Thanks to this property of tropicamide, patients are already for a long time those suffering from drug addiction, for whom taking the next dose simply meant coming to their senses, were able to feel a real “high” again.

And in addition, drug addicts managed to save money, since taking tropicamide allowed them to reduce the dose of the drug they took by almost half. However, as they say, you have to pay for everything, and along with the intensification of the feelings of drug intoxication, the consequences of drug addiction also became stronger. The pains of drug withdrawal became so terrible and unbearable that most drug addicts could not stand it and committed suicide.
In addition, as it turned out, the use of tropicamide itself caused drug addicts drug intoxication. For this reason, many tend to consider this medical drug drug. But this substance is not a derivative of opium.
Under the influence of tropicamide, drug addicts do not experience exactly the same sensations that they feel while under the influence of morphine, heroin, or something similar. These sensations are more similar to those that drug addicts experience when under the influence of hallucinogens.

These days there are many drug addicts who do not have the money to purchase drugs. A buy tropicamide without prescription For narcotic use it didn’t cost anything, because its sale in pharmacies was not limited by anything a year ago. In addition, this drug was quite cheap. And although this substance is not a derivative of opium, it still represents serious threat for a person. "High" from tropicamide lasts only a short time, no more than half an hour, and therefore drug addicts have to “run” to the pharmacy for the next portion several times a day.

Tropicamide - consequences of taking

Using this medical product to enhance the effect of drug intoxication caused by other drugs, or to hide the symptoms of drug use can lead to very serious consequences:

1. Irreparable damage to the eyes is a sharp decline in vision, leading to blindness. The pupils are artificially dilated all the time, too much light falls on the retina, which over time begins to perceive light poorly, and sooner or later all this leads to the development of blindness;
2. The addict's immune system is weakened. He becomes susceptible to many infectious diseases;
3. The internal organs of a drug addict, as a result of prolonged intoxication with tropicamide, cannot withstand the load and cease to function normally - which leads to numerous metabolic disorders. In addition, taking tropicamide leads to the development of: nephritis, hepatitis, liver cirrhosis, toxic myocardial dystrophy - these are the most frequent consequences the use of tropicamide, which in most cases can be fatal;
4. Development organic damage human central nervous system. Encephalopathy, epilepsy, etc.
   In case of tropicamide overdose to the human body significant damage is also caused. A drug addict can fall into coma, his body may be seized with convulsions, and in the case of a severe overdose of tropicamide, the person may stop breathing. In such situations, the addict needs urgent medical care. He needs to do a cleansing gastrointestinal tract and then give a drug that can adsorb the remaining toxic substances.

Treatment of tropicamide addiction in our center

Tropicamide- eye drops, which are used in ophthalmology as a means for dilating the pupil (mydriatic). Used to dilate the pupil during diagnostic procedures or surgical interventions, to relieve spasm of accommodation, in complex treatment inflammatory diseases anterior section eyes (keratitis, iridocyclitis, uveitis).
The active component of the drug, tropicamide, belongs to the group of m-anticholinergics. The mechanism of action of the drug is associated with blocking receptors of the iris and ciliary body. 5 to 10 minutes after instillation of Tropicamide eye drops, short-term dilation of the pupil (mydriasis) and paralysis of accommodation are observed. This effect lasts for approximately 4 - 6 hours, after which the original pupil size is completely restored.
Attention: the drug may increase intraocular pressure!
After instillation into the conjunctival sac, Tropicamide easily penetrates the conjunctiva; a certain amount of the drug enters the nose through the nasolacrimal duct and is absorbed into the systemic bloodstream, which causes some side effects.

Indications for use

Tropicamide eye drops used to dilate the pupil during the diagnosis and treatment of certain eye diseases, in particular, inflammatory processes with localization in the anterior sections eyeball(keratitis, iridocyclitis, uveitis). Drops are also used when performing certain diagnostic procedures (ophthalmoscopy, determination of refraction) or surgical interventions on the lens, vitreous body or retina.

Mode of application

Tropicamide eye drops can only be used as prescribed by a doctor. Before prescribing the drug, it is recommended to determine the intraocular pressure. The frequency and duration of use of the drug is determined by the ophthalmologist.
To dilate the pupil, instill 1 drop of a 1% solution or 2 drops of a 0.5% solution; if necessary, eye drops can be re-instilled after 10-15 minutes. In children, only 0.5% Tropicamide solution can be used. For decreasing side effects For use in the treatment of spasm of accommodation (false myopia) and inflammation of the eyes, it is advisable to instill drops before bedtime.
To reduce the likelihood of the drug entering the nasal cavity through the nasolacrimal duct, it is recommended to use a pad during instillation index finger press on the skin in the area of ​​the inner corner of the eye.

Side effects

While using ophthalmic dropsTropicamide The following side effects may occur: eye irritation (discomfort, redness, lacrimation), temporary impairment of visual acuity, increased intraocular pressure, photophobia.
Besides local symptoms, systemic reactions may occur, which may manifest themselves in the form of weakness, headache, nausea, dizziness, and palpitations.

Contraindications

:
Usage Tropicamide prohibited in case of increased intraocular pressure (glaucoma), individual intolerance to the components of the drug.
The use of Tropicamide eye drops in infants and elderly patients, as well as during pregnancy and breastfeeding, requires special caution and should only occur under the supervision of a physician.

Pregnancy

:
Application Tropicamide during pregnancy is possible only in cases where the expected benefit to the mother outweighs the potential risk to the fetus.
The drug should be used with caution during lactation (breastfeeding).

Interaction with other drugs

Drugs from the group of histamine receptor blockers (antiallergic drugs), MAO inhibitors, anticholinergic drugs, benzodiazepines enhance the effect Tropicamide.
Adrenergic blockers weaken the effect of this drug.
Simultaneous administration with nitrates, haloperidol, corticosteroids, nitrites increases the risk of increased intraocular pressure.

Overdose

:
Overdose symptoms Tropicamide may develop if the recommended instillation regimen of the drug is not followed (use of more high doses). In severe cases, speech and motor agitation, dry mucous membranes, increased heart rate, and loss of orientation occur.

Storage conditions

After opening the bottle of drops Tropicamide can be used for no longer than 4 weeks.

Release form

Eye drops (0.5%) Tropicamide in a dropper bottle of 10 ml; eye drops (0.5% and 1%) in 10 ml bottles.

Compound

:
Basics active substance drops Tropicamide- tropicamide 0.5% (5 mg in 1 ml) or 1% (10 mg in 1 ml), benzalkonium chloride; sodium chloride; disodium edetate dihydrate; hydrochloric acid; purified water.

Main settings

Name:	TROPICAMIDE
ATX code:	S01FA06 -

Self-medication can be harmful to your health.
You should consult your doctor and read the instructions before use.

Tropicamide: instructions for use

Compound

The solution contains the active ingredient - tropicamide - 5 mg/ml or 10 mg/ml; excipients sodium chloride, sodium edetate, benzalkonium chloride, hydrochloric acid, purified water

Description

Transparent colorless solution without mechanical inclusions

pharmachologic effect

Mydriatic Blocks m-cholinergic receptors of the iris sphincter and ciliary muscle, quickly and a short time dilates the pupil and paralyzes accommodation. The mechanism of action of tropicamide is competitive antagonism towards acetylcholine.

Pupil dilation begins 5 minutes after a single instillation of the drug into the conjunctival sac, reaches a maximum after 15-20 minutes and persists for 1 hour with instillation of 0.5% drops and 2 hours with instillation of 1% drops. Full recovery pupil size occurs after 3-5 hours.

Maximum paralysis of accommodation after instillation of 1% drops 2 times with an interval of 5 minutes occurs after 25 minutes and lasts about 30 minutes. Full recovery occurs in approximately 3 hours

After instillation of the drug into the conjunctival sac, tropicamide is slightly subject to systemic absorption (especially in children and the elderly).

Indications for use

Tropicamide is a short-acting anticholinergic drug used as a mydriatic and cycloplegic, indicated in the following situations:
-for diagnostic purposes for fundoscopy and cycloplegic refraction;
-in pre- and postoperative conditions, when the use of short-acting mydriatics is necessary

Contraindications

Hypersensitivity to tropicamide, other similar drugs or excipients.
Patients with prostatic hypertrophy, intestinal obstruction or pyloric stenosis.
Patients with glaucoma or a predisposition to glaucoma.
Children under 7 years of age (cycloplegia).
First trimester of pregnancy.
During the treatment period, you should not wear soft contact lenses.

Pregnancy and lactation

The use of tropicamide is contraindicated in the first trimester of pregnancy, and in the next two trimesters its use is possible if the benefit to the mother outweighs the risk to the fetus. Tropicamide is released in breast milk, That's why breast-feeding should be discontinued on the day of use of the drug.

Directions for use and doses

Mydriatics" the usual dose of 1-2 drops is instilled into the conjunctival sac 15-20 minutes before the examination.
Cyclopegia: the usual dose is 1-2 drops, instillation can be repeated after 5 minutes. To prolong the effect, it is recommended to add 1 additional drop every 20-30 minutes.
Directions for use: To limit systemic absorption and side effects, repeated use should be avoided.
To prevent contamination of the applicator (dropper plug) and solution, avoid touching it to the eyelids, adjacent surfaces or other surfaces. The bottle should be kept closed between uses.
Tropicamide is not adequate for paralysis of accommodation in children. A stronger cyclopelegic agent such as atropine may be required. Children under 7 years of age are not recommended to use a 1% solution of tropicamide (only a 0.5% solution).

Side effect

The drug is usually well tolerated. Possible side effects
- blurred vision
-photophobia
- xerostomia with dry mouth and thirst
-xeroderma and temporary hyperemia of the skin, often with a burning sensation
-transient bradycardia subsequently with tachycardia, palpitations and arrhythmia
-decreased intestinal tone and motility, accompanied by flatulence and constipation
-difficulty urinating
-stimulation respiratory function
-hyperemia of the mucous membrane
-hypersensitivity reactions, manifested by redness and swelling of the face, tongue and lips, difficulty breathing and maculopapular rash, which can lead to anaphylactic shock
- hallucinations, confusion, agitation (especially in children and the elderly).

Overdose

Symptoms: local irritation and conjunctivitis, confusion, disorientation, hallucinations, ataxia, headache, increased drowsiness, paranoid and psychotic reactions, hyperthermia, high blood pressure, dizziness, vomiting, diarrhea, stimulation of respiratory function, skin rash, loss of consciousness, coma, death from breath holding.
Treatment: thoroughly rinse the eyes with water, symptomatic therapy, in case of ingestion, gastric lavage and the use of activated charcoal, the use of physostigmine are recommended for therapeutic control nervous excitement It is possible to use diazepam; hypoxia and acidosis should be corrected.

Interaction with other drugs

Concomitant use of anticholinergics and histamine H1 receptor blockers, phenothiazines, tricyclic antidepressants, procainamide, quinidine, MAO inhibitors, benzodiazepines and antipsychotics mutually enhances the effect of each other
friend.
With the simultaneous use of tropicamide and nitrates, nitrites, alkalizing drugs, disopyramide, corticosteroids and haloperidol, intraocular pressure may increase with concomitant angle-closure glaucoma.
Reduced digestive motility may affect the absorption of other medications.

Precautionary measures

Drops should be instilled into the lower conjunctival sac. To reduce the resorptive effect, it is recommended to apply light pressure with a finger on the area of ​​the lacrimal sacs for 2-3 minutes after instillation.
To limit systemic absorption and side effects, repeated use should be avoided.
It should be used with caution in patients with diseases accompanied by tachycardia (thyrotoxicosis, heart failure, etc.), as well as in patients with cardiac ischemia and hypertension.
Caution should be exercised when using the drug in children and elderly people (over 65 years of age) due to increased risk development of side effects.
Contact lenses. Since Tropicamide contains benzalkonium chloride, soft (hydrophilic) lenses should be removed during instillation. Lenses can be put on no earlier than 15 minutes after instillation.
Application in pediatrics. Tropicamide is not recommended for children under 7 years of age.