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Consequences of "Postinor": reviews. "Postinor": application

A synthetic drug with a contraceptive effect, pronounced gestagenic and antiestrogenic properties. With the recommended dosing regimen, levonorgestrel suppresses ovulation and fertilization if sexual intercourse occurs in the preovulatory phase, when the possibility of fertilization is greatest. It may also cause changes in the endometrium that prevent implantation. The drug is not effective if implantation has already occurred.

Efficacy: with the help of Postinor tablets, pregnancy can be prevented in approximately 85% of cases. The more time passes between sexual intercourse and taking the drug, the lower its effectiveness (95% during the first 24 hours, 85% from 24 to 48 hours and 58% from 48 to 72 hours). Thus, it is recommended to start taking Postinor tablets as soon as possible (but no later than 72 hours) after sexual intercourse, if no protective measures have been taken. At the recommended dose, levonorgestrel does not have a significant effect on blood clotting factors, fat and carbohydrate metabolism.

Pharmacokinetics

At orally Postinora drug is quickly and almost completely absorbed. Absolute bioavailability is almost 100% of the dose taken. After taking 0.75 mg of levonorgestrel, Cmax in serum equal to 14.1 ng/ml is achieved after 1.6 hours. After reaching Cmax, the content of levonorgestrel decreases. T 1/2 is about 26 hours.

Levonorgestrel is eliminated in approximately equally kidneys and through the intestines exclusively in the form of metabolites. The biotransformation of levonorgestrel corresponds to the metabolism of steroids. Levonorgestrel is hydroxylated in the liver, metabolites are excreted in the form of conjugated glucuronides. Pharmacologically active metabolites of levonorgestrel are unknown. Levonorgestrel binds to serum albumin and sex hormone binding globulin (SHBG). Only 1.5% of the total dose is in free form, and 65% is associated with SHBG.

Release form

Tablets white or almost white, disc-shaped, chamfered, with circular engraving "INOR ." on one side.

Excipients: colloidal silicon dioxide, potato starch, magnesium stearate, talc, corn starch, lactose monohydrate.

2 pcs. - blisters (1) - cardboard packs.

Dosage

The drug is taken orally. You must take 2 tablets in the first 72 hours after unprotected intercourse. The second tablet should be taken 12 hours (but not later than 16 hours) after taking the first tablet.

To achieve a more reliable effect, both tablets should be taken as soon as possible after unprotected intercourse (no later than 72 hours).

If vomiting occurs within 3 hours after the 1st or 2nd dose of Postinor tablet, then you should take another Postinor tablet.

Postinor can be used at any time of the menstrual cycle. In case of irregular menstrual cycle, pregnancy must first be excluded.

After taking emergency contraception, a local barrier method (eg, condom, cervical cap) should be used until the next menstrual period. The use of the drug during repeated unprotected sexual intercourse during one menstrual cycle is not recommended due to the increased frequency of acyclic bloody discharge/bleeding.

Overdose

Increased severity of side effects. There is no specific antidote. Symptomatic therapy is carried out.

Interaction

At simultaneous administration liver enzyme inducer drugs accelerate the metabolism of levonorgestrel.

The following drugs may reduce the effectiveness of levonorgestrel: amprecavil, lansoprazole, nevirapine, oxcarbazepine, tacrolimus, topiramate, tretinoin, barbiturates including primidone, phenytoin and carbamazepine, drugs containing St. John's wort (Hypericum perforatum), and rifampicin, ritonavir, ampicillin, tetracycline, rifabutin, griseofulvin. Levonorgestrel reduces the effectiveness of hypoglycemic and anticoagulant (coumarin derivatives, phenindione) drugs. Increases plasma concentrations of GCS. Women taking these drugs should consult a doctor.

Drugs containing levonorgestrel may increase the risk of cyclosporine toxicity due to inhibition of its metabolism.

Side effects

Allergic reactions: possible - urticaria, rash, itching, swelling of the face.

Transient side effects that occur with different frequencies and not requiring drug therapy: sometimes (1-10%) - vomiting, diarrhea, dizziness, headache, soreness of the mammary glands, delayed menstruation (no more than 5-7 days; if menstruation is delayed for more than long term, pregnancy must be excluded); often (more than 10%) - nausea, fatigue, pain in the lower abdomen, acyclic spotting (bleeding).

Indications

Emergency (postcoital) contraception (after unprotected sexual intercourse or unreliability of the contraceptive method used).

Contraindications

adolescence up to 16 years;
severe liver failure;
pregnancy;
rare hereditary diseases, such as lactose intolerance, lactase deficiency or glucose-galactose malabsorption;
hypersensitivity to the components of the drug.

With caution: diseases of the liver and biliary tract, jaundice (including a history), Crohn's disease, lactation.

Features of application

Use during pregnancy and breastfeeding

Postinor is contraindicated for use during pregnancy. If pregnancy occurs while using an emergency method of contraception, then based on the available data, no adverse effect of the drug on the fetus has been identified.

Levonorgestrel is excreted in breast milk. After taking the drug breast-feeding should be stopped for 24 hours.

Use for liver dysfunction

The drug is prescribed with caution to patients with diseases of the liver and biliary tract; it is contraindicated in severe liver failure.

Use for renal impairment

Data on the use of the drug in patients with impaired renal function are not provided.

Use in children

The drug is contraindicated in adolescence up to 16 years old.

Special instructions

Postinor should be used exclusively for emergency contraception. Reuse Postinor is not recommended for use during one menstrual cycle.

The effectiveness of Postinor tablets after unprotected sexual intercourse, during which no contraception, decreases over time:

The drug does not replace the use permanent methods contraception. In most cases, Postinor does not affect the nature of the menstrual cycle. However, acyclic bleeding and a delay of menstruation for several days are possible. If menstruation is delayed by more than 5-7 days and its character changes (scanty or copious discharge) pregnancy must be excluded. The appearance of pain in the lower abdomen and fainting may indicate an ectopic (ectopic) pregnancy.

Teenagers under 16 years of age exceptional cases(including rape) a consultation with a gynecologist is necessary to confirm pregnancy.

After emergency contraception, a consultation with a gynecologist is recommended to select the most appropriate method of permanent contraception.

Emergency contraception does not protect against sexually transmitted diseases.

In case of gastrointestinal dysfunction (for example, Crohn's disease), the effectiveness of the drug may be reduced.

Impact on the ability to drive vehicles and operate machinery

The effect of Postinor on the ability to drive vehicles and operate machinery has not been studied.

1 tablet contains 750 mcg , as well as colloidal anhydrous silicon dioxide, magnesium stearate, potato and corn starch, talc, lactose monohydrate.

Release form

Tablets packaged in blisters of 2 pcs. The package contains 1 blister.

Postinor birth control pills are flat, approximately 6 mm in diameter, chamfered, almost white in color, with the inscription “INOR” engraved on one side.

Pharmacological action

The drug helps prevent pregnancy and causes effects in the body similar to those of hormones corpus luteum ovaries, and also suppresses the effects caused .

Pharmacodynamics and pharmacokinetics

What is Postinor?

Postinor is a remedy with a pronounced antiestrogenic And progestogenic activity. These properties of the drug make it difficult to conceive early stage and help prevent pregnancy.

Pharmacodynamics

It is not known exactly how Postinor works. Contained in tablets levonorgestrel prevents ovulation and fertilization of the egg if UPC (unprotected sexual intercourse) occurs before ovulation (when the probability of fertilization is highest).

Levonorgestrel also causes changes in the endometrium, which make it difficult for a fertilized egg to penetrate the mucous layer of the uterine cavity. In cases where attachment ovum has already started, the drug does not give the expected effect.

Wikipedia states that the mechanism of action levonorgestrel is implemented most successfully when the size of the dominant follicle is 17 mm. The drug best suppresses ovulation no later than three days before it.

Efficacy of tablets

The probability of pregnancy after using Postinor tablets is 15-42%. The effect after administration is better, the less time has passed after NPC.

If the drug was taken within 24 hours, its effectiveness is 95%, in the next 24 hours it decreases to 85%, on the third day - to 58%. There is no point in taking the drug later than 72 hours.

Is Postinor harmful?

Pharmacokinetics

Absorption in the digestive canal when taken orally is rapid and complete. In the body, the drug binds to SHBG and albumin: approximately 65% of the dose taken is associated with SHBG, only 1.5% is in free form.

96 minutes after taking the tablet, plasma concentration levonorgestrel reaches 14.1 ng/ml. Then there is a 2-stage decrease in Cmax.

The drug is well distributed in tissues and organs.

Its biotransformation occurs in the liver. The resulting metabolic products (conjugated glucuronates) are pharmacologically inactive.

Levonorgestrel excreted from the body exclusively in the form of metabolic products. About half of the dose taken is excreted in the urine, the rest in feces. The value of the T1/2 indicator varies from 9 to 14.5 hours.

With milk into the body infant When taken by a nursing woman, Postinor reaches about 0.1% of the dose.

Indications for use

“Emergency” contraception in case of failure of the chosen method of contraception or after NPC.

Contraindications

A contraindication to the use of the drug is intolerance levonorgestrel or any of the auxiliary ingredients contained therein.

The drug is used in pediatric practice. Data regarding its use in girls under 16 years of age are limited, therefore Postinor is not recommended for use in adolescence without medical supervision.

Side effects of Postinor: why is the drug dangerous?

In the annotation for the drug, the manufacturer reports that the most common reaction to the use of levonorgestrel is nausea .

In addition, the following side effects of Postinor were recorded during the studies:

dizziness;
headache;
And vomit ;
nausea;
not related to the menstrual cycle ;
disruption of the menstrual cycle (namely, a delay in menstruation after taking the pill for more than a week);
increased fatigue.

Post-marketing observations have shown that sometimes (rather rarely) the use of the drug may be accompanied by: hypersensitivity reactions ( , the appearance of skin rashes, skin itching), , pain in the pelvic area and/or abdomen, swelling of the face.

Why is Postinor harmful?

Reviews of side effects allow us to conclude that, according to women, the most unpleasant phenomena after taking Postinor are:

bleeding (in some reviews it is mentioned that, not knowing how to stop bleeding after Postinor, the woman was forced to seek medical help);
strong hormonal imbalance And pronounced violations cycle (many cases have been described when, after taking Postinor, there are no periods for several cycles; for some, it takes up to a year to restore the regularity of menstruation).

This list can include the appearance of “male” characteristics, metabolic disorders And acne .

Sometimes the consequences of taking the Postinor tablet manifest themselves in the form of miscarriage of subsequent pregnancies and infertility.

To minimize harm to the body, the drug should be used no more than 3-4 times a year.

Postinor tablets: instructions for use

How to take Postinor?

The instructions for Postinor indicate that the contraceptive effect is ensured by taking two tablets (provided that the first tablet is taken in the first 3 days after NPC). A twelve-hour interval is maintained between doses 1 and 2.

If within 3 hours after taking the drug (regardless of whether 1 or 2 doses), you should immediately take another 750 mcg levonorgestrel (3rd tablet).

The product can be used in any phase of the menstrual cycle. Required condition is the absence of a woman’s delay in menstruation.

After taking the pills, before the start of your next period, it is recommended to use barrier contraception (cervical cap or condoms).

Taking the drug is not a contraindication for continuing the use of hormonal agents for regular contraception.

How can you tell if the drug has worked?

The tablet begins to act immediately after dissolution and absorption in the intestinal tract.

Evidence that the drug has “worked” is menstruation.

Bleeding after use excludes pregnancy in approximately 95-85% of cases if it begins 3-6 days after taking the pill.

What might a delay after Postinor indicate?

If after using the drug there is no bleeding or bleeding begins later than the specified period, the woman is recommended to undergo an examination by a gynecologist to rule out pregnancy.

You should consult a doctor not only if your period is late, but also if, after taking Postinor, the consequences are expressed in the form of bleeding that is unusually heavy for a woman. The causes of such bleeding may be exceeding the recommended dose and negative effects levonorgestrel on endometrium of the uterus .

Sometimes women note that they have brown discharge after taking it. The phenomenon is considered normal if the discharge appears within a few days, thus ending the menstruation artificially induced by the pills. However, for some women, spotting may continue for up to a month.

Most likely, this is an individual reaction to severe stress for the reproductive system, but only a doctor can accurately diagnose the cause of the discharge.

Causes for concern are menstrual bleeding lasting more than 14 days, lack of full periods, the appearance of clots or heavy brown discharge, pain.

When should I get my period after taking the pill?

It is impossible to say exactly when your period will begin after using Postinor. The tablets contain a large amount levonorgestrel , therefore, even a single use of the drug does not leave its mark on the body.

In most cases, after taking the product menstrual cycle remains the same. Sometimes bleeding may begin earlier or slightly later. Normally, the delay should not be more than 5-7 days. Otherwise, pregnancy should be excluded.

After reception levonorgestrel A woman is advised to visit a doctor who will help her choose the most suitable method of regular contraception.

Is it worth taking Postinor if NPK occurs during menstruation?

In women with irregular cycle there is a chance of getting pregnant even during menstrual bleeding. The advisability of using “urgent” contraception if UPC occurred during menstruation can be determined by a doctor.

How often can you take Postinor?

To the question “How often can you take emergency contraceptive pills?” Doctors answer that drugs like Postinor are not intended for systematic use. They are used only in emergency situations and no more than 3-4 times a year.

Overdose

Clinical picture of overdose hormonal agents emergency contraception not described. Most likely, the first signs of poisoning will be nausea and breakthrough bleeding.

Postinor does not have a specific antidote.

Interaction

In combination with liver enzyme inducers, there is an increase in metabolism levonorgestrel .

The effectiveness of drugs that contain levonorgestrel , may be reduced when used simultaneously with:

barbiturates ;
preparations of St. John's wort (Hypericum perforatum);
rafibutin ;
ritonavir ;
phenytoin ;

Women taking these drugs should consult their doctor before taking Postinor.

Levonorgestrel-containing drugs may cause increased toxicity , which is associated with a possible suppression of its metabolism.

Terms of sale

According to the recipe.

Storage conditions

Tablets should be stored at a temperature of 15-25°C.

Best before date

Special instructions

“Emergency” contraception are intended for occasional use and do not replace a regular method of birth control.

“Emergency” contraception does not always prevent pregnancy. If there is any doubt about the CPD time or if unprotected act occurred more than 72 hours during the same cycle, the possibility that the fertilized egg has already implanted in the uterine wall cannot be ruled out.

In this regard, the use of tablets during the next sexual intercourse may be ineffective. If the cycle is delayed by more than 5 days, if atypical bleeding develops on the day of the expected menstruation, as well as if there are other reasons to suspect pregnancy, the fact of pregnancy should be excluded.

After reception levonorgestrel there is a risk of developing ectopic pregnancy . The absolute probability of this is low, since the drug interferes with ovulation and fertilization.

Ectopic pregnancy may persist despite the occurrence of uterine bleeding.

Most likely in women who have reported fainting or severe pain in the abdomen, as well as if there is a history of surgery on the fallopian tubes, , or PID .

Based on this, patients at risk are not recommended to take Postinor tablets.

Taking the pills may slightly change the pattern of bleeding, but in most cases the next menstruation begins a maximum of a week after the usual date.

If menstrual bleeding is delayed by more than 5 days, it is necessary to exclude the fact of pregnancy.

The drug should not be used by women with serious liver pathologies. The effectiveness of the tablets may be adversely affected by severe malabsorption (eg, granulomatous enteritis ).

For those suffering similar diseases women before undergoing emergency contraception It is recommended to consult a doctor.

Postinor tablets contain lactose, which should be warned about in patients with lactase deficiency And disorders of glucose and galactose absorption .

The drug is ineffective as regular contraception and is not an alternative to it. You should also remember that this remedy does not replace necessary measures precautions related to protection against STD .

If a woman applies for repeated use of Postinor, the doctor should recommend that she use long-term methods of birth control.

Research on Impact levonorgestrel on management ability vehicle or working with mechanisms were not carried out, but one should forget about the possibility of dizziness. Eskinor-F .

Which is better - Escapelle or Postinor?

Escapelle and Postinor are synonyms. The basis of both is levonorgestrel . Only in the first case its concentration is 1.5 mg/tablet, and in the second - 0.75 mg/tablet. That is Escapelle in the case of NPC, it should be taken once, and Postinor should be taken in 2 doses with an interval of 12 hours.

Which is better - Zhenale or Postinor?

Active substance Genale - synthetic antiprogestin . The substance is a derivative norethisterone and is used to terminate pregnancy early stages. Its content in each tablet is 10 mg.

Mifepristone is non-hormonal agent , which reversibly and transiently blocks exclusively peripheral PRs (receptors progesterone ). Depending on the phase of the menstrual cycle, the drug prevents the release of luteotropin , delays or blocks ovulation and causes disturbances in the transformation of the endometrium, which, in turn, complicates the implantation of the egg.

WHO data indicates that the use low doses mifepristone more effective and safe than emergency contraception using levonorgestrel .

In addition, it has been experimentally proven that the contraceptive effect mifepristone does not decrease with increasing interval between NPC and administration Genale up to 120 hours. This is also a significant advantage of the latter over Postinor.

If necessary “urgent” contraception it is enough to take 1 tablet during the first 72 hours Genale . The drug is used 2 hours before meals.

What is better - Postinor or Ginepristone?

Active substance Gynepristone is also mifepristone at a concentration of 10 mg/tablet. Thus, the drug has the same advantages over Postinor as Genale .

The product has high efficiency, is characterized by the absence of significant side effects and can be used for occasional contraception in women with irregular sex life.

In addition, the drug is more affordable compared to Postinor. Its price is Russian pharmacies approximately 100-120 rubles lower than the price of Postinor.

Postinor and alcohol

Is it possible to combine Postinor tablets with alcohol? There are no recommendations in this regard in the manufacturer's instructions.

However, it should be remembered that alcohol is not compatible with the vast majority of pharmaceutical products.

Drinking alcoholic beverages in combination with Postinor can cause a sharp dilation, and then an equally sharp constriction of blood vessels, which in turn will complicate the woman’s condition when the drug provokes rejection of the uterine mucosa.

In addition, alcohol increases the level of liver enzymes, thereby speeding up metabolism. And since biotransformation levonorgestrel is carried out in the liver, the contraceptive effect of Postinor while drinking alcohol can be very questionable.

IN sex life every couple has had it happen at least once emergency situation: the condom broke, the woman forgot to take a pill that protects against unwanted pregnancy on time, or the partner, in a fit of passion, failed to control his emotions.

It would seem that conception is inevitable, but this is not so. Even if the incident occurred on the days most favorable for pregnancy, the situation can be corrected with the help, the most popular of which is Postinor.

Effect of Postinor on a woman’s body

This drug and its analogues (Microlut, Escapelle, etc.) are characterized by a triple mechanism of action. The active substance of Postinor is an artificial analogue of the main pregnancy hormone - progesterone - levonorgestrel, contained in the drug in large quantities(0.75 mg).

Thanks to its effect on the body, Postinor blocks or delays ovulation, preventing the release of a mature egg from the ovary into fallopian tube, prevents the fertilization of the egg by sperm, making the cervical mucus thicker to prevent sperm from penetrating into the uterine cavity, and changes the usual structure of the endometrium lining the woman’s uterus, thereby making implantation impossible. If implantation of a fertilized egg into the uterine wall has already occurred, Postinor will not stop the pregnancy process

When to use Postinor?

It is recommended to use Postinor only in in case of emergency(rape, torn condom, prolapse of the uterine device, missing an oral contraceptive, etc.). IN foreign countries it can only be purchased by prescription, but in Russia Postinor and its analogues are sold in free access, which is actually the reason for the frequent abuse of this drug, leading to problems in the female reproductive system.

If you use Postinor in accordance with the instructions, taking into account all the side effects and contraindications, no more than once every six months (and preferably as little as possible), as a rule, there will be no serious consequences It shouldn’t have any impact on a woman’s health. But if you neglect the instructions and often use the products without consulting a gynecologist, you can greatly harm the body, even leading to infertility.

How to use Postinor? Postinor instructions

Postinor is taken on any day of the menstrual cycle. Packaged medicinal product contains 2 tablets, which should be taken 12 hours apart. To achieve maximum effect The first tablet should be taken as soon as possible after unprotected intercourse, but no later than 72 hours.

The sooner you drink it, the less chance you have of an unwanted pregnancy. The second tablet is taken 12 hours after the first. If you experience vomiting within 2 hours after taking Postinor, it is better to repeat the drug.

The time for transporting a mature egg and its implantation into the uterine wall takes about 5 days, so the effectiveness of post-coital contraception greatly depends on the time of administration after intercourse. If from the moment unprotected contact More than 4 days have passed, there is no point in drinking Postinor, because... he won't help anymore.

Postinor contraindications

A special indication for taking the drug is the presence of a regular menstrual cycle. Postinor should not be used by women who have any liver or gallbladder diseases, increased sensitivity to any component of the drug, hereditary diseases (glucose-galactose malabsorption, lactase deficiency, lactose intolerance).

It is contraindicated to use Postinor more than once every 3-6 months, since frequent use This medication increases the risk of developing ovarian dysfunction, which can lead to infertility. Postinor should not be used by pregnant and lactating women.

Side effects of taking Postinor

Any medicine has side effects, and Postinor is a strong, high-dose hormonal drug that, with frequent or misuse may cause the development of serious diseases.

Common side effects of taking Postinor:

Intestinal dysfunction and digestive system, manifested by diarrhea, vomiting;
Headache, dizziness;
Lethargy, weakness;
Allergic reactions

Reproductive side effects:

Uterine bleeding;

A common side effect after consuming Postinor is the appearance. They arise due to a sharp increase in gestagens in the body, which are responsible for lining the inner layer of a woman’s uterus.

Impaired ovarian function leading to infertility;

If Postinor is used too often, constant bleeding can cause depletion of the ovaries and impair their function, as well as provoke anemia.

Dysmenorrhea, amenorrhea, infertility;

Another serious one side effect from taking Postinor is expressed in the development of a woman (pain during menstruation), (lack of menstruation) and even. Women who use emergency contraception may experience disruptions to their menstrual cycle, hormonal imbalances, and severe pain during menstruation.

If after taking the drug Postinor for 2 weeks or more, you must definitely consult a gynecologist to exclude pregnancy or negative influence drug on the reproductive system.

Postinor, and its analogues Escapel, Microlut, Eskinor F, are a means of contraception only in emergency cases, that is, for life-threatening reasons, such as rape, rupture of a condom during sexual intercourse.

Why can't it be used on an ongoing basis? This drug in developed countries can only be purchased with a prescription, unlike in Russia, since Postinor has serious side effects.

However, some women use these drugs quite often, without consulting a gynecologist and not knowing about the consequences, complications, side effects of Postinor and its analogues. To understand what effect these drugs have on the body, you should know the mechanism of their action.

Mechanism of action of Postinor

Postinor causes a lot of side effects and its use is possible only in extreme cases. During puberty and women with (planning to have children in the future), its use is not advisable, since this can lead to disruption hormonal levels in a woman and cause infertility in the future.

Postinor and its analogues are intended only for emergency prevention of pregnancy. The active ingredient of the drug is levonorgestrel, of which there is 0.75 mg in one tablet, which is considered a lethal dose. In low-dose oral contraceptives, for example, this dose of levonorgestrel is contained in 20 tablets. The Postinor package contains 2 tablets, which are taken 12 hours apart for 72 hours after unprotected sexual intercourse. The mechanism of action of levonorgestrel is as follows:

preparation blocks ovulation- prevents a mature egg from leaving the ovary
when ovulation has already occurred, Postinor prevents implantation of the fertilized egg in the uterine cavity - in this case it essentially has an abortifacient effect
leads to a change in cervical mucus, it becomes thicker, which interferes with the penetration of sperm into the uterine cavity.

When the implantation of a fertilized egg into the uterine wall has already occurred, the drug becomes ineffective, since all gestagens have the property of suppressing motor activity muscles of the uterus.

Contraindications

The use of Postinor is contraindicated for use in the following cases:

liver dysfunction, serious illnesses liver
teenage girls under 16 years old
during lactation the drug penetrates into breast milk therefore it is contraindicated during breastfeeding
at uterine bleeding unknown origin
for individual intolerance
at herpetic infection and others infectious diseases genitourinary system
for diseases associated with enzyme deficiency- impaired absorption of glucose, galactose (lactase deficiency)
at malignant neoplasms any localization
with a genetic predisposition to thrombosis

Use with caution when ulcerative lesions Gastrointestinal tract, diseases of the biliary tract.

Side effects of Postinor

Any medicine has side effects, but Postinor is powerful hormonal drug, which in some cases can become a trigger for the development serious problems with a woman's health. Therefore, in developed countries this drug is available only by prescription and is considered not safe method contraception. Side effects of Postinor are as follows:

Intestinal dysfunction - diarrhea
Digestive disorders - vomiting, diarrhea
Headache, dizziness
Intermenstrual bleeding
Breast tension
Flu-like symptoms
Weakness, lethargy

If you experience any side effects from taking Postinor or other unusual signs of illness, you should consult a doctor.

Side effects from the reproductive system, impact on the woman’s reproductive function in the future

Considering that 1 tablet contains huge amount active substance, in a woman’s body after taking Postinor, a real hormonal imbalance. The instructions for the drug say that it is not recommended to use it more than 4 times a year. But some women often neglect these recommendations and take it uncontrollably, sometimes even several times per menstrual cycle, which is very dangerous and prohibited.

Since Postinor should be taken when there is a high probability of pregnancy (ovulation period) - at this time the mucous membrane of the uterus has not yet matured, which leads to dysfunction of the ovaries, and then they produce either less or more hormones. And even with a one-time use of the drug, it is required certain time(in each case individually) to restore ovarian function.

Therefore, if a woman with existing menstrual irregularities:

irregular menstruation
teenagers under 16 years old

If you take the drug even once, such disruptions can be permanent and cause infertility in the future.

The impact of this hormonal agent, especially on an ongoing basis, leads to the fact that the function of the ovaries begins to fade, become depleted, and the production of hormones gradually becomes less and less. This causes irregularities in the menstrual cycle and can affect a woman's reproductive ability. In some cases, taking the drug leads to amenorrhea (lack of menstruation) and, as a consequence, persistent infertility. Even a timely visit to a gynecologist in such cases cannot guarantee successful recovery normal menstrual cycle and the likelihood of pregnancy.

If a woman has periodic uterine bleeding, taking Postinor and its analogues can intensify it and lead to the need for emergency treatment. medical care, therefore, in such cases, taking the drug is unacceptable. Also, one of the side effects of Postinor is engorgement and soreness of the mammary glands, and the appearance of discharge from the nipples.

Consequences of "Postinor": reviews. "Postinor": application

Pharmacokinetics

Release form

Dosage

Overdose

Interaction

Side effects

Indications

Contraindications

Features of application

Use during pregnancy and breastfeeding

Use for liver dysfunction

Use for renal impairment

Use in children

Special instructions

Release form

Pharmacological action

Pharmacodynamics and pharmacokinetics

What is Postinor?

Pharmacodynamics

Efficacy of tablets

Is Postinor harmful?

Pharmacokinetics

Indications for use

Contraindications

Side effects of Postinor: why is the drug dangerous?

Why is Postinor harmful?

Postinor tablets: instructions for use

How to take Postinor?

How can you tell if the drug has worked?

What might a delay after Postinor indicate?

When should I get my period after taking the pill?

Is it worth taking Postinor if NPK occurs during menstruation?

How often can you take Postinor?

Overdose

Interaction

Terms of sale

Storage conditions

Best before date

Special instructions

Which is better - Escapelle or Postinor?

Which is better - Zhenale or Postinor?

What is better - Postinor or Ginepristone?

Postinor and alcohol

Effect of Postinor on a woman’s body

When to use Postinor?

How to use Postinor? Postinor instructions

Postinor contraindications

Side effects of taking Postinor

Mechanism of action of Postinor

Contraindications

Side effects of Postinor

Side effects from the reproductive system, impact on the woman’s reproductive function in the future

Other side effects of Postinor