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What does Validol help with, and how to properly take the drug in drops, tablets and capsules? The most effective regimen for taking Validol in capsules.

Validol is a “good old” medicine, time-tested and with virtually no contraindications. Many of us carry this sedative with us, just in case. Validol is a low-toxic drug, does not accumulate in the body and does not cause allergic reactions. This remedy will help relieve headache, will calm down in case stressful situation. Therefore, it is recommended to have a bottle of drops or a package of Validol tablets in every home.

Its main effect is sedative. After taking the drug, expansion occurs blood vessels. The body also increases the synthesis of enkephalins and endorphins - painkillers and sedatives. The production of other compounds that affect permeability is also activated. vascular walls and eliminating painful sensations.

The drug can be purchased at the pharmacy chain, where it is presented in the form of drops, lozenges and sublingual capsules. Let's find out more about the drug validol, its use, what the instructions say, indications for use and its composition. To answer the questions posed, let’s open and read the instructions attached to it:

What is the composition of Validol as a drug?

Drops: Menthol (25%) isovaleric acid, dissolved in alcohol. It is a clear, oily liquid with a menthol odor.

Capsules: 1 capsule contains 50 mg of menthol and menthylisovalerianate. Take for resorption by placing under the tongue.

Tablets: 1 tablet contains 60 mg of menthol and menthylisovalerianet. Also taken by resorption.

What are Validol's indications for use?

As is known, Validol has sedative properties, calming nervous system, and also causes a reflex vasodilator effect. Therefore, it is prescribed to be taken for such painful conditions as neuroses and hysteria. It is recommended for use for symptoms seasickness, as it reduces the intensity of nausea, preventing the occurrence of vomiting. It can be used externally to relieve itching after insect bites.

What is the dosage and use of Validol?

Drops: Dissolve in 50 ml of water (4-5 drops). It’s even better to put 3-5 drops on a piece of refined sugar, then put it in your mouth and dissolve.

Tablets: take half or 1 piece. sublingually - that is, placed under the tongue until completely dissolved.

Capsules: take 1 capsule 2 times a day sublingually.
As prescribed by a doctor, the dosage regimen of this drug can be increased.

External use: to eliminate itching, pain, swelling of the skin from insect bites, lubricate the bite site with the preparation and leave until absorbed.

What are Validol's side effects?

Validol very rarely causes negative manifestations. But sometimes nausea and increased lacrimation may occur. Patients sometimes complain of headaches and dizziness. In such cases, consult your doctor to replace validol with a drug that is more suitable for you.

What are the contraindications for Validol?

Among the contraindications of Validol, the instructions for use include low blood pressure (hypotension), as well as in the presence of individual intolerance to certain components of the drug.

Important!

You need to understand that Validol is a drug and should not be taken at your own discretion. The fact is that many continue treatment with validol, not suspecting that the existing disease requires more effective medications. In particular, it is taken for angina pectoris, which should not be done! To treat this disease, as well as for coronary disease heart requires medications recommended by a doctor! And validol in these cases is not your help. You will only make the disease worse. It acts to a large extent as a sedative and local irritant.

Validol is good only for mild, fleeting attacks. If you have angina pectoris, it is better to use a stronger drug - glycerin, and then only after medical examination. Glycerin expands more efficiently and quickly coronary vessels. This is what is required during angina attacks.

The same can be said about cardialgia. This disease is similar to angina pectoris, only the pain in the heart area is not squeezing and pressing, but a stabbing, aching character. Cardialgia is often accompanied by a burning sensation in the heart area. In this case, validol can relieve pain at first, but the disease itself is not cured. Others will be needed here, strong drugs prescribed by a doctor.
For example, they are often prescribed: verapamil, inderal.

In conclusion:

Validol - wonderful medicine, which has been used by patients for many decades. This effective drug, which has a calming effect. He shoots well and quickly emotional stress. Its effectiveness as an analgesic, as well as a coronary agent, is beyond doubt.

But if you are regularly bothered by heart pain or have attacks, you must first understand the cause of their occurrence. You should contact a cardiologist and undergo an examination. Based on its results, the doctor will decide whether it is necessary to prescribe stronger medications, carry out complex treatment, or whether it is enough to take only validol. Be healthy!

What is the drug for and what is it made of? How often can it be used? What exactly is Validol taken for? The drug is indicated for use in following cases:

Validol tablets are taken by holding them under the tongue until completely dissolved. Thus, you can use no more than 3 tablets per day. "Validol" capsules are drunk no more than 4 times a day. The dose for adults is no more than 2 units of tablets or capsules, and the daily dose should not exceed 4. exceptional cases The intake of Validol in capsules increases.

Manufacturers produce the medicine "Validol" in 20 pieces per package, if these are capsules, and in tablets - 6 or 10 pieces weighing 60 mg.

Validol tablets contain the following chemical ingredients:

  1. About 5% natural menthol or mint extract. In terms of content, 1 tablet contains 0.06 milligrams of the substance.
  2. Used for filler excipients to impart flavor characteristics to the medicine. This is a powder made from sugar and calcium stearate.

The color of the tablets is crystal white or slightly yellowish. The shape is a flat cylinder, and there is a chamfer in the middle. The smell is quite strong, menthol. During production, inclusions of a gray tint and a coating of white powder are allowed.

Advantages of the drug

The use of Validol internally promotes vasodilation and also has a calming effect on the nervous system, while the patient does not fall asleep. Validol contains components that help improve blood circulation and reduce pain.

In general, this drug has its own taste properties Reminds me of menthol. The action of "Validol" is associated with reflex functions body or affecting nerve endings.

This effect occurs when:

  • stimulating pain and the formation of enkephalins;
  • interaction between cells of the nervous and immune systems;
  • substances capable of producing particles to reduce headaches;
  • peptides that play a role in regulating pain;
  • vascular patency;
  • other metabolic processes.

Using the drug internally causes the release of some active components, such as kinin and histamine. After taking the medicine, you can feel the result after 5 minutes. The components included in the medicine partly remain inside the liver, and other products are excreted in the feces. The composition of the product does not change when excreted in urine or air.

In what cases should you not take the drug?

The instructions for use also stipulate cases in which taking the medicine is impossible.

These include:

  • intolerance to both individual components and the complex of ingredients contained;
  • reduced blood pressure;
  • initial stage of heart attack;
  • failure to reach adulthood.

The use of Validol when driving should be carried out with extreme caution. Also, you should not get carried away with it when doing work that requires special attention. It is not excluded side effects, such as dizziness and desire to sleep. How to take the product during pregnancy? The answer to this question can be obtained from your attending physician. As a rule, he prescribes taking a medicine in cases where the effectiveness of taking the medicine may exceed the risk for the birth of a future person. But these are only exceptional measures.

If it is not possible to lower blood pressure and, for example, pain in the area chest do not pass, then you need to act in other ways. To remove high blood pressure, combination therapy must be used. For this purpose, nitrates are additionally prescribed.

The indications for the use of Validol include the following: important property: the drug should not be prescribed to people with the disease diabetes mellitus, since the medicine also consists of sweet products.

Adverse events after taking the medicine

What Validol helps with has already been discussed above, but the question arises, does this product have side effects?

The instructions for use of Validol, along with the positive effects, also describe side effects:

  • feelings of nausea;
  • possible dizziness;
  • increased production of tears.

There is no need to take special measures to eliminate these factors. They will gradually pass without the help of doctors.

Does Validol increase or decrease blood pressure? This primarily depends on the patient’s health status.

When the product interacts with other drugs

It is possible that some actions of the drug may be enhanced when taking other medications concomitantly. But it is possible that there are cases of incompatibility of such solutions.

List of possible interactions:

  • at simultaneous administration nitrates will reduce headaches and heart pain;
  • if you use Validol with glucose, it is possible that the pressure will increase slightly;
  • "Validol" at high blood pressure, taken together with drugs that have a calming effect on the nervous system, will help you fall asleep peacefully;
  • combined use with drugs that lower blood pressure will help enhance this effect.

“Validol” with glucose can be consumed, but only after consulting a specialist.

Cases of overdose

An overdose of Validol entails various negative consequences. Therefore, it is important to know how to take Validol correctly.

List of these phenomena:

  • Validol with glucose can cause an increase in blood sugar;
  • an overdose of Validol in some cases causes dizziness and migraines;
  • possible distortion of the heart;
  • decreased blood pressure;
  • negative effect on the central nervous system;
  • allergic manifestations.

If these cases occur, you should rinse your stomach.

Analogs

In the modern pharmaceutical industry there are many analogues of Validol.

Its substitutes are:

  • "Drops of Zelenin";
  • "Aurocard";
  • "Corargin";
  • "Pumpan";
  • "Convaliant-valerian drops";
  • other medicines.

Substitutes for the drug have the same effect and have virtually no differences from the original. Analogs of Validol may differ only in price.



General characteristics. Compound:

Active ingredient: 1 tablet contains a solution of menthol in menthyl ester of isovaleric acid (natural menthol - mint extract - 4.9%) 0.06 g (60 mg);
excipients: crushed sugar (powdered), calcium stearate.

Pharmacological properties:

The drug exhibits a calming effect on the central nervous system, and also has a moderate reflex vasodilator (coronary lytic) effect through reflex irritation of sensitive nerve (“cold”) receptors of the oral mucosa. Stimulation of receptors is accompanied by the induction of the release of endorphins, enkephalins, dynorphins and other opioid peptides that play important role in reducing pain sensitivity, normalizing vascular permeability and regulating other important mechanisms functioning of the cardiovascular and nervous systems. Under the influence of the drug, physiologically active substances are released - histamine, kinins, etc.
When administered sublingually, Validol® is absorbed from the oral mucosa. The therapeutic effect occurs in approximately 5 minutes.
After absorption, it is biotransformed in the liver and excreted in the urine in the form of glucuronides.

Indications for use:

Directions for use and dosage:

The tablets are kept in the mouth (under the tongue) until completely dissolved.
A single dose for adults is 1-2 tablets; daily - 2-4 tablets. If necessary, the daily dose can be increased. Maximum daily dose- 600 mg.
The course of treatment is up to 7 days.

Features of application:

Use during pregnancy or breastfeeding.
The use of the drug during pregnancy or breastfeeding is possible if, in the opinion of the doctor, the expected positive effect for the mother exceeds the potential risk for the fetus/child.
The ability to influence the reaction rate when driving a vehicle or working with other mechanisms.
In the first hours after taking the drug, caution is required when driving vehicles or doing work that requires increased attention, due to possible side effects (dizziness and drowsiness).
Children. There is no experience in using the drug to treat children.

Side effects:

With prolonged use, mild, short-term drowsiness may occasionally be observed, which quickly passes on its own.
Possible development allergic reactions, including Quincke's edema, rash, itching.

Interaction with other drugs:

Validol® enhances sedative effect psychotropic drugs, opioid analgesics, alcohol and anesthetics.
It is possible to potentiate the effect of antihypertensive drugs when used simultaneously with Validol®.
Validol® reduces the severity of headaches caused by taking nitrates.

Contraindications:

Increased sensitivity to the components of the drug.
Expressed arterial hypotension; . Childhood.

Appropriate safety precautions for use.
The drug contains sugar, which should be taken into account by patients with diabetes.

Overdose:

Symptoms: nausea, excited state, cardiac dysfunction, drop in blood pressure, depression of the central nervous system.
Treatment: it is necessary to discontinue the drug and carry out symptomatic therapy.

Storage conditions:

Best before date. 2 years. Do not use the drug after the expiration date indicated on the package. Store in a dry place at a temperature between 8 °C and 15 °C. Keep out of the reach of children.

Vacation conditions:

Over the counter

Package:

6 or 10 tablets in a blister; 1 blister included in a pack.
6 or 10 tablets in a blister, without packaging.


Instructions for use

Validol belongs to m medical drugs affecting the cardiovascular system.

Used in the following cases:

  • as a component combination therapy during attacks of angina pectoris;
  • neurocirculatory dystonia of the cardiac type, as well as functional cardialgia;
  • neuroses;
  • states of hysteria;
  • as an anti-vomiting agent for air and sea sickness.

How to take

Validol tablets: 1 tablet up to 3 times a day, keeping under the tongue until completely dissolved.
Validol capsules: 1 capsule per day, up to 4 times.
A single dose for adults is up to 2 tablets or capsules, a daily dose is up to 4 tablets or capsules. The daily dose can be increased if necessary.

Release form, composition of the drug

Validol is available in capsules (pack of 20 pieces, 0.1 g each) and tablets (pack of 6 and 10 pieces/60 mg).

1 tablet of Validol contains:

  • solution of menthol in isovaleric acid menthyl ester (natural menthol - mint extract - 4.9%) / 0.06 g (60 mg);
  • Excipients: powder or crushed sugar, Ca stearate.

The color of the tablet is white or slightly yellowish. The shape is flat-cylindrical with a chamfer and a dash. They have a characteristic menthol smell. On the surface of the tablets, inclusions of a grayish color and a powdery coating are allowed.

Useful properties

The drug Validol has a reflex vasodilator effect of a moderate nature and a calming effect on the central nervous system, while having a sedative effect on it.

As a result of using Validol, regional blood circulation improves and the severity of pain decreases.

In its effect on the body, Validol resembles menthol. Therapeutic effect Validol is caused by a reflex reaction associated with irritation of nerve endings. Irritation of receptors on the surface of the mucous membranes is characterized by stimulation of the release and formation of enkephalins, dynorphins, endorphins, peptides, which play an important role in the regulation of pain, vascular permeability and other metabolic processes.

Under the influence of irritating substances, a number of other endogenous physiological substances are released active substances(histamine, kinin). When taken sublingually, the effect of the drug begins 5-7 minutes after administration. The components of Validol are partially transformed in the liver. Transformation products are excreted from the body through the intestines with bile. In unchanged form, the drug is excreted in the urine and air that a person inhales.

Contraindications

Validol is contraindicated in the following cases:

  • intolerance to the constituent components of the drug;
  • myocardial infarction in the initial stage;
  • children's age due to lack of experience in pediatrics.

For the first time after taking Validol, you should be careful when administering complex mechanisms And vehicle, as well as any other work with increased attention. Possible side effects: dizziness and drowsiness.

During pregnancy and breastfeeding, the drug can be taken if the expected therapeutic effect for the mother is much higher than the potential risk for the unborn child.

If chest pain does not go away after taking it, it is necessary to exclude acute coronary syndrome. In combination therapy for the treatment of angina attacks, if there is no positive effect in the first 5 minutes, it is recommended to prescribe nitrates.

Since Validol contains sugar, it is prescribed with caution to people with diabetes.

Side effect

Very in rare cases after using the drug the following are possible:

  • nausea;
  • lacrimation.

These phenomena go away on their own. None medical procedures not required.

Interaction with other drugs

  • simultaneous use with nitrates can reduce headaches resulting from the use of nitrites;
  • if you take sedatives together with Validol, the effect of the latter will increase;
  • taking neurotropic drugs that depress the central nervous system, together with Validol, will contribute to better falling asleep and sound sleep;
  • the effect of antihypertensive drugs due to combined use with Validol will be enhanced.

Overdose

Validol is a truly mysterious remedy. At least in the fact that he managed to live two full lives. Born in the 9th century in Germany and successfully used in the Western pharmaceutical market for almost 30 years, it was supplanted by competitors. He unexpectedly found his second birth in the USSR. Validol was always in the first aid kit, in the purse, in the jacket pocket of every adult who felt where his heart was located. Despite the abundance of cardiotropic drugs, it still does not leave pharmacy shelves.

Instructions for use of Validol in capsules

This drug is popular mainly because its onset therapeutic effect occurs almost at lightning speed, within a maximum of five minutes, due to the inclusion of a reflex reaction leading to vasodilation. Among various forms release of the drug (tablets, drops, capsules and solution), the most popular was the encapsulated form. Bursting under the pressure of the tongue, the gelatin shell releases the medicine contained under it, this allows the effect to develop even faster.

Composition and pharmacological properties of the drug

The drug is prepared by dissolving menthol in isovaleric acid menthyl ester. Once on the surface of the oral mucosa, binding to receptors there, the substance causes their activation, which leads to a number of physiological reactions.

Stimulation of “cold” receptors in the mucous membrane of the sublingual region leads to dilation of the blood vessels of the heart and improvement of blood flow in coronary arteries. Optimal dosage menthol has a calming effect on the central nervous system.

According to recent data, irritation of peripheral nerve endings leads to the release of opioid peptides (endorphins, enkephalins, dynorphins, etc.), which reduces the severity of pain and improves the emotional state of a patient who has just suffered an attack of angina.

Indications for use

The drug is indicated for patients with cardiovascular pathology in history, who are often susceptible to emotional overload, experience nervous tension or are in a state of chronic stress. Validol is indicated:

  • as part of complex therapy during attacks of angina pectoris, rapid heartbeat, and prevents the development of myocardial infarction;
  • for cardialgia (pain in the heart) of a functional nature;
  • in combination with other drugs in the treatment of disorders of the autonomic nervous system;
  • as an adjuvant for hysteria and neuroses;
  • to relieve headaches;
  • for kinetosis - to alleviate seasickness and air sickness (nausea and vomiting);
  • with toxicosis during pregnancy;
  • with muscle cramps.

Directions for use and doses

Validol in capsules is prescribed sublingually (singing the tongue) and is kept until the gelatin shell is completely dissolved. For adults single dose is 0.05-0.1 g (1–2 capsules), the maximum daily dose is 4 capsules of 0.05 g or 2 capsules of 0.1 g. Can be increased daily dosage up to the maximum permissible - 0.6 g. However, before taking this step, the individual sensitivity of the body to the components of the drug should be established.

Contraindications


The only contraindication according to the instructions is personal intolerance to the components of the product (in in this case, active ingredients and components gelatin capsule). In general, we can say that the drug is well tolerated.

Interaction with other drugs:

  • combined use with nitroglycerin reduces the intensity of headaches caused by taking nitrates;
  • parallel use with antihypertensive drugs may enhance the reduction in blood pressure;
  • aggravates the effect sedatives, can also improve falling asleep and sleep quality;
  • joint reception with narcotic analgesics, psychotropic drugs and alcohol-containing substances aggravates their effect.

Interaction of Validol capsules with alcohol

The fact of the positive interaction of menthol in menthylisovalerate and ethyl alcohol raises doubts. It is known that alcohol has a vasodilating effect, just like Validol. In addition, although the latter causes a sedative effect, combining it with alcohol can cause a paradoxical reaction and increase the state of anxiety and agitation.

The drug has both local and systemic action, being absorbed and penetrating into the bloodstream. The main transformation of the substance occurs in the liver with the participation of glucuronide enzymes. Alcohol is inactivated with the participation of another enzyme, alcohol dehydrogenase. Despite the fact that their metabolic pathways do not cross, both substances are foreign to the body and force the liver to work intensively, overloading it.

Therefore, it is unsafe to combine these two substances, possible reactions are poorly understood and may be unexpected. This combination is especially dangerous in patients with pathology of the cardiovascular system.

Use of the drug among children

Due to the fact that the use of Validol in childhood is observed extremely rarely, and there is no convincing evidence of the safety of its use; its prescription in childhood should be carried out exclusively by a pediatrician; self-medication in this case is extremely dangerous!

The drug is contraindicated in children under 12 years of age. The main indications for its recommendation are those diagnosed in a child neurotic disorders, hysteria, stressful conditions. In this case, the dosage is no more than 0.05 g (1 capsule) under the tongue.

Side effects

The practice of more than one decade and positive reviews from patients indicate that the drug is well tolerated. In rare cases, nausea, dizziness, lacrimation, pain in the iliac region, and allergic manifestations (urticaria, Quincke's edema) may occur. These conditions go away on their own after reducing the dosage or stopping the drug and do not require special treatment.

Overdose

High concentrations of active substances in the blood potentiate the effect positive effects and can dramatically and dramatically lower blood pressure. There is a possibility of distortion of their action with the development of cardiac dysfunction, the occurrence of intense headaches and nausea to vomiting, overexcitation with a subsequent state of depression of the central nervous system.

There is no specific antidote. In rare cases, gastric lavage and hemodialysis are required. Depending on the observed reactions, symptomatic therapy is carried out.

Analogues of Validol in capsules

Among the drug analogues there are a number of medicines that have similar composition and release form:

  • Corvalol-N No. 10 and 30 in capsules (PJSC Farmak, Ukraine) is an over-the-counter product containing: mint oil, alcohol ester of alpha-bromoisovaleric acid, menthol solution in menthyl ester of isovaleric acid, hop oil. Indicated for neuroses and neurosis-like conditions, complex treatment arterial hypertension, as a means for dilating coronary arteries and for tachycardia, as well as for spastic intestinal pain.
  • Cormenthol 0.1 g No. 15 in capsules (Biopharm, Romania), composition: solution of levomenthol in menthyl isovalerate, vitamin E, olive oil. Recommended by doctors for mild attacks of angina, neurosis and hysteria, as an antiemetic for kinetosis.
  • Corvalment 0.1 No. 30 in capsules (KVZ, Ukraine). It's almost complete analogue Validola with similar composition, indications, contraindications and side effects are the same.
  • Barboval No. 10 in capsules (Farmak PJSC, Ukraine) - similar in composition to Corvalol N, with the addition of phenobarbital, i.e., it has an enhanced sedative and hypnotic effect.

In cases where taking Validol is not recommended for some reason, the attending physician may recommend a number of substitutes that are similar in their spectrum of action:

  • Advocard (FarCoS, Ukraine) is a metabolic drug for the complex treatment of angina pectoris of various variations, with post-infarction changes in the myocardium, myocarditis, myocardial dystrophy).
  • Pumpan (Richard Bittner AG, Austria) - anticoagulant plant origin, which has the ability to stabilize high blood pressure and slow down heart rate).
  • Kratal (Borshchagovsky Chemical Plant, Ukraine) – cardiotonic, antioxidant, antihypoxant, antiarrhythmic, antiplatelet agent based on hawthorn, motherwort with taurine.
  • Tonginal (Richard Bittner AG, Austria) is a homeopathic medicine with complex action.
  • Rhythmokor (FarKoS, Ukraine) – consists of potassium and magnesium gluconates. Antihypoxic agent designed to help normalize heart rate, also enhance the effect of antiarrhythmic drugs.
  • Tricardin (Belmedpreparaty, Belarus) – calming and lowering blood pressure herbal remedy etc.

Validol during pregnancy and lactation


Showed high efficiency and got a lot positive feedback the drug is recommended for pregnant women in the first trimester of pregnancy. It is prescribed for severe toxicosis with nausea and frequent, repeated vomiting. It also helps reduce excess salivation and eliminate bloating.

Be that as it may, there have been no large-scale studies on the effectiveness and safety of using the drug during pregnancy and lactation, so the responsibility for prescribing it lies with the doctor, who must correctly weigh the benefits and possible harm regarding the health of the mother and the unborn child.

Validol is absorbed into the blood and penetrates into breast milk, it is not shown when breastfeeding, only if absolutely necessary and on the strong recommendation of the treating doctor.

Price of Validol in capsules in comparison with analogues

Price per large packaging with a dosage of 0.05 g No. 40–58 111 rub.

Terms of sale, terms, storage features

Validol – over-the-counter drug, and no official order is required to purchase it. However, it should be noted that the patient assumes full responsibility for possible negative consequences, so it is still recommended to be observed by a doctor during the entire period of use of the medicine.

The maximum shelf life of the drug is 2 years from the date of production. It should be stored in a dry, cool place, out of reach of children, at temperatures up to 25 degrees Celsius.