Mezim: indications for use and how to take. The drug Mezim forte - composition for optimal digestion

Mezim is a medicine that compensates for the lack of pancreatic enzymes. Mezim belongs to the group of enzyme preparations. The drug Mezim improves digestion. Typically used in the treatment of chronic pancreatitis (to compensate for impaired pancreatic function), as well as in the treatment peptic ulcer, gastritis, enteritis, intestinal infections, dysbacteriosis, occasionally to facilitate the digestion of food. Mezim is available in the form of pink, enteric-coated tablets.

What does Mezim contain?

The drug Mezim contains pancreatic enzymes: amylase, lipase, protease. One tablet of the drug Mezim contains: 3500 IU of lipase, 4200 IU of amylase and 250 IU of protease. These enzymes facilitate the digestion of fats, proteins and carbohydrates. Mezim is also available in the form of Mezim Forte 10,000. The number “10,000” means the number of units of the lipase enzyme contained in one Mezim Forte tablet.

In what cases should Mezim be used?

The main indications for the use of the drug Mezim are as follows:

Dosage and method of use of the drug Mezim

Mezim is available in tablet form. The dose of Mezim is determined individually. Mezim in tablets: Recommendations for using the drug Mezim in tablets: Mezim is usually taken orally immediately before meals, during meals or immediately after meals. When taking Mezim, the tablet should not be chewed. The medicine Mezim should be taken with warm water (it is strictly forbidden to take the tablets with tea or juice). Mezim tablets are best taken standing or sitting. After taking Mezim, you should not lie down for 3-4 minutes, otherwise the medicine may break down in the esophagus and not reach the stomach. If the patient is prescribed the use of more than 2 drugs (including Mezim), then the interval between taking each drug should be from 5 to 15 minutes. The duration of use of the drug Mezim is from several days to several months or years. In some cases (with severe chronic pancreatitis), Mezim should be taken all the time.

Use of the drug Mezim during pregnancy and breastfeeding

As a rule, the use of the drug Mezim is not prohibited during pregnancy and lactation. But in case of mild forms of chronic pancreatitis during pregnancy, it is advisable to refrain from taking Mezim.

In what cases should Mezim not be used?

Mezim is not recommended for use if the patient has hypersensitivity to the drug or to its main components. The use of Mezim in acute pancreatitis or chronic pancreatitis in the acute stage is strictly contraindicated.

Side effects when using the drug Mezim

The most common side effects when using the drug Mezim include: mild nausea, vomiting. Taking Mezim extremely rarely can cause anaphylactic shock, urticaria, Quincke's edema, and atopic dermatitis. At long-term use Mezim in large doses may develop hyperuricemia (increased blood levels uric acid). Rarely: when taking the drug Mezim, signs of intestinal obstruction occur. As a rule, these signs occur in cystic fibrosis.

Special instructions for using the drug Mezim

Prescribing Mezim to children is decided individually depending on the severity of the disease.

Interaction of the drug Mezim with other drugs

With long-term simultaneous use of the drug Mezim with iron preparations (Sorbifer, Ferrous Sulfate), a decrease in the absorption of iron at the intestinal level is possible. Decreased iron absorption may cause the patient to develop the following symptoms anemia: weakness, pallor skin, decreased performance, cracks in the skin of the heels, brittle nails. If you have the above symptoms, you should temporarily stop taking Mezim or replace it with another drug. The effectiveness of Mezim is reduced when used simultaneously with antacids that contain calcium or magnesium. It is necessary to increase the dose of Mezim when used simultaneously with antacids.

Overdose of Mezim

There have been no reports of an overdose of the drug Mezim, even when using large doses of the drug.

Expert opinion of the Polismed Medical College

We have collected frequently asked questions and prepared answers to them

What works better Mezim or Festal

Please tell me, I suffer from pacreatitis, which drug is better for this disease: mezim or festal. People respond differently. Some people prefer festal, others prefer mezim. I would like to hear an authoritative opinion from a specialist. Mezim and Festal contain the same main active ingredient - the enzyme of the animal pancreas - pancreatin. But Festal also contains elements of ox bile. When this powdery substance enters the human body, it stimulates the human body to produce its own enzymes. Thus, we can say that its effect is wider than that of Festal. But the doctor must select the drug, taking into account personal characteristics every organism.

Which is better for treating pancreatic diseases Mezim or Pancreatin

I have problems with digestion, after eating food, especially fatty food, I feel heaviness in the stomach, nausea, periodic nagging pain and constipation. The examination showed a sluggish process in the pancreas. What is better for me to take: pancreatin or mezim? If you already have a disease of the pancreas, you should give preference to Mezim, since it contains more main active ingredients and they are in known proportions. Its disadvantage in relation to Pancreatin is its increased cost. Pancreatitis is more suitable for digestive disorders associated with enzyme deficiency. In your case, if there is a process in the pancreas, you should take Mezim

Can pregnant women take mezim if they have digestive problems?

Please help me deal with the problem. I am 6 months pregnant. For the last few weeks, heaviness in the stomach has been occurring after eating, there is no appetite, and nausea appears from many foods. Gas formation has increased. Diarrhea often alternates with constipation. The local doctor said that this was due to enzyme deficiency, which often occurs in pregnant women. He advised me to drink mezim. Isn't this dangerous? No, it’s not dangerous, Mezim should help you. It will promote faster breakdown and absorption of food, which will lead to a decrease or even disappearance of your complaints and improved well-being. This drug will not have any effect on a child. negative action. But it is better for you to find out the duration of the course of treatment and dose from your doctor. This is necessary to take into account your individual characteristics.

Mezim or Creon, which is better for digestive problems?

Help me figure it out, I have last year after eating, constant discomfort, heaviness in the stomach, periodic diarrhea. I was examined, everything is fine with the intestines, and with the pancreas too. I started taking Mezim on my own, but found out that Creon has a stronger effect. Maybe it makes sense to take it? Creon is similar in its characteristics and composition to mezim, but the active ingredients are contained in more high doses. Due to the structure medicinal form And excipients the drug is able to penetrate into more distant areas of the gastrointestinal tract, exerting an enzymatic effect there. Therefore, it is more suitable for a patient suffering from pancreatic pathology. Your case is more consistent with mezim.

Is it possible to give mezim to children with indigestion?

Doctor, please tell me whether Mezim can be given to children, at what age and in what doses? Yes, children can be treated with Mezim if indicated. A doctor should prescribe this drug if the child has chronic pancreatitis, cystic fibrosis, chronic intestinal infections, flatulence, problems with stool, etc. It is important to calculate the dose correctly. Children under 12 years of age are recommended to take the drug in a dose of up to 1500 IU per 1 kg of weight. If the child is prescribed any other medications, then it is necessary to pause after taking Mezim for at least 15,020 minutes.

Is it possible for pregnant women to drink Mezim?

Hello, I'm pregnant. Duration 16 weeks. She consulted a doctor with complaints of difficult digestion. I was prescribed Mezim. It has no contraindications for pregnant women. Is it possible to drink it, or is it still harmful? Most doctors recommend taking Mezim for pregnant women if indicated and if there are corresponding complaints. There are no contraindications in the instructions. But on the other hand, there are also no studies on this topic. If it is possible to do without taking the drug, then you should do so. If, nevertheless, it is necessary to take it, then this should be done only with the participation of a doctor, who takes responsibility for possible side effects that are so undesirable for a pregnant woman.

For problems with digestion, digestion of heavy, fried or fatty foods Doctors recommend that patients take special enzyme preparations. One of these is Mezim, produced in different dosages and aimed at helping the work gastrointestinal tract. Familiarization with the instructions for use of the medication will help you use the drug correctly for each type of treatment of the disease.

Mezim Forte - instructions for use

Mezim tablets belong to the group of enzyme preparations containing active ingredients enzymes that improve digestion. The active ingredients of the drug are lipase, amylase and protease. This complex of pancreatin components, which has minimal enzymatic ability, normalizes the functioning of the stomach and improves food digestion.

Compound

Three types of Mezim are produced, differing in different concentrations of enzymes. More details about the composition in the table:

Concentration of lipase enzyme, units

Amylase concentration, units

Protease concentration, units

Microcrystalline cellulose, magnesium stearate, colloidal silicon dioxide, sodium carboxymethyl starch

Lactose monohydrate, magnesium stearate, microcrystalline cellulose, colloidal silica, crosspovidone

Lactose monohydrate, magnesium stearate, microcrystalline cellulose, colloidal silica

Shell components

Macrogol, talc, hypromellose, titanium dioxide, azorubine varnish, polyacrylate dispersion, simethicone emulsion

Hypromellose, bergamot flavor, methcarylic acid-ethacrylate copolymer, vanilla flavor, triethyl citrate, macrogol, titanium dioxide, carmellose sodium, talc, simethicone emulsion

Release form

All three varieties of Mezim are available in the form of film-coated tablets. Medicine Forte and 10000 has pink, 20000 – white-gray. The shape of the tablets is flat-cylindrical, with a characteristic smell of pancreatin, except for Mezim 20000 - it has the aroma of bergamot and vanilla. The medication is available in blisters of 10 or 20 pieces, 1-5 blisters per pack.

Pharmacodynamics and pharmacokinetics

The drug is designed to compensate for the deficiency exocrine function pancreas. It consists of digestive enzymes pancreatin, which facilitate the digestion of proteins, carbohydrates and fats. This promotes more complete absorption of substances into small intestine and improvement of trypsin activity. Pancreatin is a powder obtained from pig pancreas. Its components have proteolytic, amylolytic and lipolytic effects.

The tablets are coated with an acid-resistant coating that does not dissolve hydrochloric acid gastric juice and protects enzymes from inactivation. Dissolution of the shell occurs at a neutral or slightly alkaline intestinal pH level. Amylolytic activity shows its full significance only in the treatment of cystic fibrosis, but even with a significant decrease in pancreatic secretion, amylase has good activity. There are no data on the pharmacokinetic properties of the drug; it is unknown whether it has systemic action on the body.

Indications for use

Before use, you should consult your doctor and study the instructions for the drug Mezim - the instructions for use of the drug include a number of indications. These include:

  • chronic pancreatitis, cystic fibrosis, insufficiency of the pancreas and its exocrine function;
  • lack of enzymes for normal digestion;
  • chronic inflammatory-dystrophic condition of the gastrointestinal tract, liver, gall bladder;
  • the patient's condition after resection, irradiation, characterized by disruption of work digestive juice, the digestive process itself, flatulence, diarrhea;
  • nutritional errors - to improve the digestion of food with normal functioning of the stomach;
  • preparation for radiography and ultrasound examination digestive organs abdominal cavity.

Mezim Forte 10000

The drug Mezim Forte 1000 has similar indications for use. K additional factors its use instructions include disorders of the gastrointestinal tract, intestinal infectious diseases and irritable bowel syndrome. More active work and increased content pancreatic enzymes in the drug implies strict adherence to the dosage.

Mezim 20000

Indications for the use of Mezim 2000 do not differ from those mentioned above. These include pancreatic insufficiency, chronic inflammation gallbladder, intestines and stomach, normalization of digestion in healthy people. The drug can also be used as part of combination therapy to improve digestion, health after resection or irradiation of the gastrointestinal tract, in preparation for research and intestinal disorders.

How to take Mezim

Instructions for use of Mezim include information about the method of administration and dosage. The latter is prescribed depending on the severity of the stomach disease. Average adult dose equal to 1-2 tablets Mezim 20000 or 2-4 Mezim 10000. The drug cannot be chewed, Mezim should be washed down with water. An increase in the dose is possible after medical supervision when the symptoms of abdominal pain weaken. The course of treatment is several days for indigestion and poor nutrition or several months and even years with constant replacement therapy.

Special instructions

At acute form pancreatitis or exacerbation chronic illness at the attenuation stage, plus while on a diet to restore digestion, it is recommended to prescribe the drug in a concentration of 20,000. The medication does not affect the concentration of attention and the speed of psychomotor reactions, therefore, during treatment it is allowed to drive and dangerous mechanisms. Patients with cystic fibrosis often experience a complication in the form of intestinal obstruction, therefore, during treatment with medication it is worth remembering possible emergence stricture

The drug contains active enzymes that can damage the oral mucosa with the formation of ulcers and wounds, so the tablets should not be chewed. Not used for weight loss. The medication contains lactose monohydrate, therefore it is prohibited for use by patients with galactose intolerance, lactose deficiency in the blood and glucose-galactose malabsorption syndrome.

During pregnancy and breastfeeding

During pregnancy or lactation, the drug should be used as prescribed by a doctor after assessing the benefit to the mother and the risk to the fetus. If the benefit outweighs the risk, the drug is permitted. The instructions do not contain information about the safety and effectiveness of using the medicine for breastfeeding, therefore it should be taken with caution, it may penetrate into breast milk, and with him in children's body.

Mezim for children

According to the instructions, Mezim for children is taken from the age of three in the dosage regimen and course set by the attending physician. The approximate dosage will be 1000 lipase units/kg of child's weight during each meal. Otherwise, the regimen for using the drug to normalize stool does not differ from that for an adult - the tablets are taken with meals and washed down with liquid.

Drug interactions

When taking the medication with other medications, you should be careful with some combinations. Risky combinations:

  • the medicine reduces absorption folic acid and iron supplements, the effectiveness of oral hypoglycemic agents;
  • antacids containing calcium carbonate or magnesium hydroxide reduce the effectiveness of the medication.

Side effects

Patients taking Mezim rarely report symptoms adverse reactions. TO possible consequences The use of the product includes those specified in the instructions:

  • allergic reactions, rash, irritation;
  • heartburn, itching, burning sensation in the abdomen;
  • sneezing, bronchospasm;
  • epigastric pain;
  • increased excretion of uric acid in the urine;
  • nausea, vomiting, diarrhea, constipation, change in stool character;
  • hyperemia, angioedema, feeling of heat, general weakness;
  • increased sensitivity;
  • symptoms are short-term and disappear after discontinuation of drugs;
  • if signs in the abdomen cause discomfort, it is recommended to consult a doctor for a dose adjustment or change in medication for treatment.

Overdose

With long-term use of high doses of Mezim, the development of hyperuricosuria (stones in the urine) and allergic reactions. In cystic fibrosis, exceeding the dosage threatens the development of hyperuricemia and strictures of fibrous colonation in the ileocecal region, ascending colon. According to the instructions, the symptoms can be eliminated by stopping the medication and carrying out symptomatic therapy. Specific methods of assistance (forced diuresis, hemodialysis) are ineffective because the drug contains natural enzymes.

Contraindications

The drug Mezim should be used with caution by pregnant and lactating women. The instructions indicate contraindications for taking pills:

  • hypersensitivity to components;
  • acute pancreatitis or exacerbation of pancreatitis, a chronic course of the disease;
  • childhood up to three years;
  • constant uncontrolled use;
  • obstructive intestinal obstruction;
  • abnormalities in bile tests.

Terms of sale and storage

You can buy Mezim without presenting a doctor's prescription. It is stored away from children at a temperature not exceeding 25 degrees for three years.

Analogues

On sale you can find direct and indirect substitutes for Mezim. The first include similar means with the same active substance, to the second - with other enzymes, but similar therapeutic effect. Popular analogues of tablets are:

  • Pancreatin;
  • Penzital;
  • Ajizim;
  • Eurobiol;
  • Zentaze;
  • Innozyme;
  • Kreazim;
  • Creon;
  • Micrasim;
  • Pangrol.

Price

You can purchase the drug via the Internet or pharmacy chains. The cost of tablets depends on their quantity in the package and the concentration of the enzyme composition. Approximate prices for Moscow and St. Petersburg.

Mezim Forte is a medicine from the group of enzyme preparations.

What is the composition and release form of the medication Mezim Forte?

The pharmaceutical industry produces medicines in pink pills, they are flat-cylindrical, with so-called plane-parallel surfaces, the edges of the dosage form are beveled, and there is a characteristic smell of pancreatin.

The active ingredient of Mezim forte is pancreatin, which has minimal enzymatic activity of proteases, lipase and amylase. The auxiliary components are as follows: microcrystalline cellulose, sodium carboxymethyl starch is present, in addition, silicon dioxide and a certain amount of magnesium stearate.

The tablet shell is formed by the following substances: talc, hypromellose, azorubine varnish, simethicone emulsion, polyacrylate dispersion, titanium dioxide, and macrogol 6000 is also added. Dosage form placed in blisters of 20 pieces.

You can buy an enzyme preparation without a prescription. The drug should be stored away from children, and the tablets should not be exposed to excessive moisture, in which case they will lose their properties. The shelf life of the medicine is three years, therefore, after this time, you should refrain from using the medicine again.

What is the effect of the Mezim forte tablet?

The medicine Mezim Forte compensates for the insufficiency of the so-called exocrine function of an organ such as the pancreas. The enzymes included in the drug, lipase, in addition, amylase, and protease, contribute to better digestion of fats, proteins and carbohydrates.

What are the indications for use of the drug Mezim Forte?

The medication Mezim forte (tablets) instructions for use allow use in the following situations:

With insufficient so-called exocrine pancreatic function, for example, with, in addition, with;

At chronic diseases stomach, intestines, in addition, liver, gall bladder. Conditions after complete or partial removal of these organs, when food digestion is disrupted, bloating occurs;

The drug is effective for errors in nutrition when food digestion is disrupted.

The enzyme preparation Mezim Forte is prescribed in preparation for diagnostic procedures, for example, to x-ray or ultrasound examination of the abdominal cavity.

What are the contraindications for use of Mezim Forte?

There are conditions when the instructions for use do not allow use of Mezim Forte. This following situations: increased sensitivity To enzyme preparation; do not use the medicine for acute pancreatitis.

What are the uses and dosage of Mezim Forte?

The dose of Mezim Forte is determined individually; it will depend on the severity of the digestive disorder. Typically, adults are prescribed 1-2 tablet forms before meals; the medication should not be chewed; they swallow it whole with the required volume of water. In addition, if necessary, a person can additionally take from 1 to 4 tablets during a meal.

The duration of treatment with Mezim Forte can vary from several days (if there is an error in the diet) to months or even years (when the patient needs to constantly carry out so-called replacement therapy).

When using the drug Mezim Forte simultaneously with iron supplements, the absorption of the latter may be slightly reduced. Simultaneous use antacids will lead to reduced effectiveness of pancreatin. Before starting treatment with these tablets, the patient should consult a doctor.

What are the side effects of Mezim Forte?

Mezim Forte tablets can provoke the development of adverse reactions, in particular, the patient complains of allergies, in addition, there is nausea, constipation or loose stool, discomfort in the epigastric region cannot be ruled out.

With long-term use of the drug Mezim Forte, especially in high dosages the patient may develop hyperuricosuria, in addition, it will be determined increased level uric acid in the bloodstream.

In isolated cases, people diagnosed with cystic fibrosis may experience the formation of strictures in the so-called ileocecal region, especially after taking the drug in excessive doses.

During development side effects to use the enzyme preparation Mezim Forte, the patient must consult a specialist, the doctor will conduct symptomatic therapy if necessary.

Overdose from Mezim forte

In case of an overdose of Mezim Forte, which we continue to talk about on this page www. . If against this background the patient’s health worsens, then it is recommended to call a doctor who will provide symptomatic treatment.

How to replace Mezim Forte, what analogues should I use?

Medicine Mezim 20000, Mezim, Pangrol10000, Panzinorm 10000, Gastenorm forte, Uni-Festal, Pankrenorm, Ermital, in addition, Creon 25000, Biozim, the drug Panzim forte, Enzistal-P, Pancreatin-LekT, Festal N, Pancreatin tablets, Pancreazym , Pancrelipase, Pancreatin, PanziCam, Pangrol 25000, Pancreatin Forte, Pancreatin concentrate, Creon 40000, as well as Penzital, Micrasim, Pancreatin, as well as the medicine Pancitrate.

Conclusion

You must take the enzyme preparation Mezim Forte as prescribed by your doctor.

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Mezim refers to an enzyme preparation that restores function digestive system. Using the drug, proteins are broken down into amino acids, and starch into oligosaccharides and maltose. In addition, Mezim has lipolytic properties - it can be used to break down fats into glycerol and fatty acids. Basics active substancePancreatin(porcine pancreatic enzyme). The preparation also contains Trypsin, with the help of which the secretion of the pancreas is suppressed.

Application

By taking Mezim, you can return the necessary enzymes to the body, thus improving digestion. The drug is covered with a special coating, which is reliable protection pancreatin from negative impact gastric juice. Thus, it is quickly released in the small intestine.

How long does it take for Mezim to work? 40 minutes after oral administration, the drug has pharmacological action. Analogues of Mezim include:

  • Festal.
  • Biozyme.
  • Creon.
  • Gastenorm forte.
  • Hermital.
  • Pancreatin.

Indications for use

Mezim should be taken when:

  • , chronic pancreatitis in case of impaired functioning of the pancreas.
  • Chronic inflammatory process in the intestines, liver, gall bladder.
  • Condition after undergoing resection (an operation during which part of the stomach was removed).

Also, the drug must be taken after being irradiated digestive organs- liver, gallbladder and increased flatulence appeared.

Doctors prescribe Mezim for:

  • Errors in diet. Often problems with internal organs occur after a person eats too fatty foods.
  • Chewing dysfunction due to a sedentary lifestyle.
  • Preparation for ultrasound, x-ray of the abdominal organs.

Contraindications

It is important to consider when not to take the drug. You should not get carried away with Mezim if you have:

  • Chronic pancreatitis worsened.

The drug is dangerous during breastfeeding, pregnancy, it can negatively affect the fetus. The doctor prescribes it only if other methods are ineffective.

Instructions

Mezim Forte contains about 10,000 pancreatin. You need to take it before you sit down to eat. The main thing is to swallow the tablet completely; you should not bite it. Need to drink a large number fruit juice, alkaline mineral water. Single dose medications for adults 2 tablets. In severe cases, 4 tablets may be prescribed.

On average, an adult is prescribed no more than 150 thousand units of lipase per day, only in the case of complete absence enzymes, 400 thousand units of lipase are prescribed.

Only a therapist can prescribe the drug for children; parents should not prescribe it themselves. Children under 2 years of age are prescribed no more than 50 thousand units, and older children 100 thousand units.

In case of replacement therapy, adults and children can take the drug for several months.

Side effects

You shouldn't get carried away with Mezim. Like others medicines it leads to serious allergies, nausea, unpleasant sensations in the stomach. At long-term use Hyperuricosuria may develop (uric acid increases in the urine). In cystic fibrosis, if the dose is exceeded, there may be serious complications in the form of stricture development.

  • Mezim Forte is necessarily prescribed for acute pancreatitis, as well as during an exacerbation of the disease. In addition, the drug is extremely necessary for dietary nutrition during the treatment of pancreatitis.
  • In case serious pathologies pancreas Mezim is drunk for a long time.
  • The drug should not be given frequently to children under 3 years of age.
  • The medicine affects driving. It is better not to drink it before work, especially if it requires increased attention from you.

Interaction with other drugs

  • While taking vitamins, Mezim may interfere with the absorption of folic acid.
  • The substance Pancreatin, which is the main component of Mezim, interferes with the absorption of glucose-lowering drugs - Miglitol, Acarbose.
  • You cannot take Mezim and iron supplements; the substance will not be absorbed by the body.
  • Simultaneous use of magnesium hydroxide, calcium carbonate, and Mezima reduces the effectiveness of the drug.

Enzyme agents that improve digestion processes.

Composition of Mezim forte

The active ingredient is pancreatin.

Manufacturers

Berlin-Chemie AG (Germany), Berlin-Chemie AG, packaged Berlin-Pharma ZAO (Germany), Berlin-Chemie AG, packaged Zio-Zdorovye (Germany), Berlin-Chemie AG/Menarini Group (Germany)

Pharmacological action

The drug compensates for the insufficiency of the exocrine function of the pancreas.

The enzymes lipase, amylase and protease included in pancreatin facilitate the digestion of fats, carbohydrates and proteins, which contributes to their more complete absorption in the small intestine.

Side effects of Mezim forte

Allergic reactions, diarrhea or constipation, nausea, discomfort in the epigastric region.

With long-term use in high doses, the development of hyperuricosuria and an increase in the level of uric acid in the blood plasma is possible.

In isolated cases, patients suffering from cystic fibrosis experience the formation of strictures in the ileocecal region after taking high doses.

Indications for use

Insufficiency of exocrine pancreatic function (chronic pancreatitis, cystic fibrosis, etc.).

Chronic inflammatory-dystrophic diseases of the stomach, intestines, liver, gall bladder.

Conditions after resection or irradiation of these organs, accompanied by impaired digestion of food, flatulence, diarrhea (as part of combination therapy).

To improve food digestion in patients with normal function gastrointestinal tract in case of dietary errors.

Preparation for x-ray and ultrasound examination of the abdominal organs.

Contraindications Mezim forte

Hypersensitivity to the components of the drug, acute pancreatitis, exacerbation of chronic pancreatitis.

Directions for use and dosage

The dose is determined individually depending on the degree of digestive disturbance.

Adults:

  • 1-2 tablets before meals,
  • without chewing and drinking water.

If necessary, take 1-4 more tablets with meals.

In children, the drug is used as prescribed by a doctor.

The duration of treatment can vary from several days (if the digestive process is disrupted due to errors in the diet) to several months or years (if constant replacement therapy is necessary).

Overdose

No data available.

Interaction

With the simultaneous use of pancreatin with iron preparations, the absorption of the latter may be reduced.

Concomitant use of antacids containing calcium carbonate and/or magnesium hydroxide may lead to a decrease in the effectiveness of pancreatin.

Special instructions

Use during pregnancy and lactation.

The safety of using pancreatin during pregnancy has not been sufficiently studied.

Use is possible in cases where the expected benefit to the mother outweighs the potential risk to the fetus.