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The embryo is in pain. Pain after embryo transfer

In an effort to find long-awaited sensations after embryo transfer, expectant mothers listen to their bodies, hoping to feel the slightest symptoms completed pregnancy. They try to feel the successful implantation of the embryo after the IVF procedure by any changes in well-being. Women are especially sensitive to their condition, for whom in vitro fertilization- the last hope of having a baby.

Specialists performing embryo transfer are confident that women’s new sensations are caused by the action of hormonal support agents that promote better survival of the embryo and some pain after the puncture. Whether there are any manifestations of implantation itself after embryo transfer or whether there are no sensations is a controversial issue.

Embryo transfer

Usually, the most complete and healthy embryos are used for transplantation, although their survival rate does not exceed 40%. The use of 5-day-old embryos is considered favorable; in this case, you can count on pregnancy in 50% of cases. It is not always possible to preserve the embryo in an artificial test tube environment for 5 days, so it is more popular to use it at 3 days of age. The transfer of embryos into the uterine cavity occurs through cervical canal using a catheter. After the procedure, you may experience the following symptoms:

  1. Pain in the lower abdomen and a feeling of tightness, especially in those women whose periods are painful. In no case should you endure pain after embryo transfer, since this condition threatens the development of uterine hypertonicity, as a result of which the embryo will not be able to attach to its mucous membrane and pregnancy will not occur. To prevent similar situation it is necessary to use drugs that relieve pain, such as no-spa or papaverine.
  2. Increase in body temperature after the end of the embryo transfer process.

Characteristic signs of pregnancy after embryo transfer

The first sensations after embryo transfer are not much different from the pregnancy obtained naturally. This may be previously unusual sensations after transfer in a successful protocol in the form of painful tension in the lower back and lower abdomen. These include the following:

However, after the embryo transfer procedure, it is not recommended to rely only on indirect signs pregnancy. Quite often similar symptoms belong to premenstrual syndrome.

Therefore, if you feel like before your period, in order to calm down, you can use test strips to determine pregnancy, which can be purchased at the pharmacy. But 100% certainty of the pregnancy result after embryo transfer during IVF can only be achieved by testing for hCG hormones (human chorionic gonadotropin). A considerable percentage of women after embryo transfer during IVF do not feel almost any symptoms of pregnancy, and to dispel all doubts it is best to resort to this analysis.

There are situations, for example, with late implantation, when during pregnancy slight bleeding may occur, which can be mistakenly considered menstruation. However, you need to remember that implantation bleeding is not profuse, rather spotting, which is different from normal menstruation.

Types of implantation

Implantation processes, depending on the period of attachment of the embryo to the wall of the uterus, can be late, in which it occurs 10 days after ovulation, and early - after 6–7 days. In the case of embryo transfer during IVF, late implantation occurs, since the embryo enters the unusual environment of the mother’s body and needs some time to adapt. In order to choose the place of attachment to the uterus for the development of pregnancy, the embryo also needs several days. According to experts, implantation after embryo transfer occurs on days 5–8.

During this period, a woman should take special care to maintain pregnancy and not take hot bath and any warming procedures, limit physical activity and lifting weights, observe correct mode, spend more time walking, eat well. Avoid hypothermia and contact with sick people, do not have sex, and it is best to adhere to bed rest for several days.

Objective sensations as a result of embryo transfer

The appearance of abdominal pain after the IVF procedure should not be scary, but this condition should not be ignored either. Since the nature of the pain is very specific, there is no certainty: what it is, symptoms of pregnancy after a successful embryo transfer, or the appearance of pain is a sign that the end of the menstrual cycle is approaching and, therefore, the beginning of a new one.
Objective sensations that confirm the presence of pregnancy:

  • as a result of embryo transfer, an increase in basal temperature is observed;
  • body temperature can also rise to 37–37.9;
  • Carrying out tests after embryo transfer can reveal the presence of hCG in the blood and urine.

It is necessary to take into account the nature of pain, discharge, the magnitude and duration of the increase in temperature after the embryo transfer procedure. Sometimes for implantation symptoms and further development pregnancy, signs of other pathologies are accepted. If you have the slightest doubt about the successful transfer of embryos, you should consult your gynecologist.

How to know about a successful pregnancy

Often women wait for some unprecedented sensation to appear after embryo transfer with successful implantation. But most often, in healthy body this procedure is almost asymptomatic and you may find some bright manifestations pregnancy fails. Primary symptoms usually appear 11–14 days after implantation and manifest themselves as normal pregnancy. It is recommended to monitor basal temperature, which is usually increased after embryo transfer. If within a few days basal temperature does not rise and remains below 37 0, then most likely you will be disappointed.

Embryo development after IVF and feelings by day of pregnancy

During development natural pregnancy all processes of ovulation, implantation and further development of the embryo throughout pregnancy have been sufficiently studied. To make it easier to imagine the picture after embryo transfer during IVF, it is necessary to understand its entire mechanism day by day. The development of embryo transfer is slightly different for 3 and 5 day old embryos. This difference is due to the fact that on the 3rd day after the embryo transfer, it still exists due to nutrition in the egg, and starting from the 5th day, the shell of the egg bursts and it passes into the blastocyst stage, beginning its existence as follows: day zero is considered the day of embryo transfer , i.e. cryotransfer, when healthy embryos are transferred to the uterus. From days 1 to 4, the blastocyst begins its movement, emerging from the shell, attaching to the walls of the uterus and implanting into it, thereby beginning the process of cell division and implantation.

Feelings after embryo transfer on the 5th, 6th, 7th, 8th day of pregnancy

On the 5th day after embryo transfer, implantation as such ends. The embryo has implanted and germ cells and placenta begin to form. Starting from day 6, the expanding placenta begins to produce hCG hormone, not yet in large quantities, but already present in the body. But already from the 7th day, the active growth of this hormone begins, which continues to grow on the 8th day.

What changes in sensations occur on days 9, 10, 11, 12 of pregnancy?

On days 9–10, the amount of the hCG hormone increases, simultaneously with the development of the fetus, and on days 11 and 12, counting from the moment of embryo transfer, a final conclusion can be made as to whether the embryo transfer was successful and whether pregnancy took place.

You can finally be congratulated: the exciting IVF procedure is completed, and in the next 2 weeks the chances of becoming a mother are greater than ever. The waiting is tedious, and if after embryo transfer your stomach hurts like before your period, then panic is the most appropriate word to describe the state of your nervous system.

The doctor insisted on emotional calm and positive thinking, but how to remain calm in the face of uncertainty?

Abdominal pain after IVF bothers 80% of women, so try to reduce your anxiety and get ready to absorb the information.

Pain may occur immediately after the transfer or several days later. For some it goes away quickly, for others it persists for weeks. Pain can vary in intensity and there may be several reasons for its occurrence.

Pulling in the lower abdomen after transplantation

Pain in the lower abdomen, which persists for several weeks after fertilization, is due to the following reasons:

  1. mechanical damage to the ovaries during IVF;
  2. ovarian hyperstimulation syndrome;
  3. possible attachment of the fetus;
  4. bloating and constipation;
  5. changes hormonal levels;
  6. enlarged uterus;
  7. constipation and increased gas formation.

Mechanical damage

The IVF protocol involves the simultaneous growth of several. Normally, only one egg matures each month. At artificial stimulation their number can reach 20 or more. To obtain mature eggs, each follicle is punctured, which is essentially a microtrauma. Therefore, you should not be surprised at the occurrence of pain immediately after IVF.

Hyperstimulation syndrome

Hyperstimulation syndrome – possible complication associated with exceeding the dose of drugs. Except nagging pain accompanied by swelling, abdominal enlargement, changes in stool, and appetite.

With mild and moderate severity The course of adjustments in nutrition and daily routine turns out to be sufficient for treatment. Symptoms accompanying hyperstimulation syndrome may persist for several weeks.

Attachment of the fetus

Most desired reason is the attachment of the embryo. Many women whose IVF outcome was positive noted the appearance of nagging pain and slight bleeding in the first days after transplantation.

Uterine enlargement

The uterus, especially in cases where several embryos mature in it, increases significantly. The ligaments that support it are stretched, causing pain in the lower abdomen. The placenta grows and develops, changing hormonal levels.


Constipation and increased gas production

And constipation and bloating are caused by a decrease in physical activity and poor nutrition.

When should you sound the alarm?

The occurrence of abdominal pain after embryo transfer, as before menstruation, can still serve as a reason for urgent appeal for help in cases:

  1. if the pain has turned from nagging to acute;
  2. if the sensations experienced cannot be called banal discomfort;
  3. if abdominal pain is accompanied by significant bloody discharge.

The symptoms listed do not always mean the worst. They may be due hormonal changes, weak attachment or other reasons. Seeing a doctor will dispel doubts. If necessary, treatment will be prescribed.

If possible, remain calm, follow the doctor’s recommendations, watch your diet, bowel movements, and be attentive to yourself. Don't be afraid to seek help if necessary and avoid self-medication.

Video


Unfortunately, there are couples who have exhausted the possibilities of conceiving a baby naturally. In such cases, the diagnosis of “infertility” sounds like a death sentence. Don't despair: modern medicine has stepped forward and most cases of infertility can be cured. The main thing is to find out the reason why pregnancy does not occur.


When determining a method of therapy for the treatment of infertility, the doctor takes into account many factors: the age of the future parents, chronic diseases, genetic features.


One of the reasons that prevents pregnancy is hormonal disorders. This factor successfully eliminated by hormonal medicines. But there are the most complex diagnoses (impaired patency of the fallopian tubes, adhesive disease of the reproductive organs, male factor infertility), for which drug treatment is ineffective. In such cases, they turn to the IVF technique.


The basis of the IVF technique is that fertilization of the female reproductive cell occurs outside female body. Fertilization of the egg in artificial conditions- the manipulation is complex. How high-quality the embryo will be depends on the properties of sperm and female germ cells, the success of the process of extracting mature cells, and the experience of the reproductive specialist.

Fertilization of the egg

After puncture of the follicles, the resulting female germ cells are sent to an embryologist. It is this specialist who evaluates the maturity of the obtained biological material and selects the highest quality cells. The eggs are placed in a nutrient medium. After four to six hours, the egg is fertilized with sperm under supervision.


If problems with conception are caused by male pathology reproductive system(the content of active sperm in semen is insignificant), to increase the likelihood successful fertilization carry out the ICSI technique. The essence this method consist of introducing a sperm into the cytoplasm of the egg using a special needle.

Embryo transfer

When preparatory activities The IVF procedure has been completed and the embryo is transferred. In order for the embryo transfer to be successful, the patient’s hormonal background and an ultrasound scan of the uterus and ovaries are examined before transfer.


The embryos are placed in a special container that is connected to a syringe. Under ultrasound guidance, the embryos are carefully placed into the uterine cavity. After completion of medical procedures, the woman remains in the gynecological chair for another forty minutes. The process does not cause pain. There may be some slight discomfort during embryo transfer. But temporary discomfort pass at the end of the procedure.


Sometimes after embryo transfer the stomach hurts and feels tight. Doctors recommend lying down for half an hour after embryo transfer to get rid of stress and tension. Usually after rest the pain goes away without a trace.


The attending physician provides extensive instruction on the specifics of further therapeutic activities. The doctor also introduces you to the extract, which contains recommendations on nutrition, physical activity, and the time for performing the test that determines successful conception.


If after embryo transfer your stomach, back hurts, or you experience bleeding, do not be alarmed. You should inform your doctor about these sensations. Only a specialist can draw conclusions about pathological conditions after embryo transfer.

Stomach pain: what does it mean and what to do

Minor abdominal pain after the IVF procedure bothers 85% of patients. Therefore, doctors recommend lowering the anxiety threshold. Pain during embryo transfer can occur during the first hours after the procedure or several days later.


The pain persists for two to three weeks:

  • Mechanical damage ovaries during IVF. The IVF program involves the simultaneous growth of several follicles. In one menstrual cycle Only one egg matures. When the ovulatory cycle is stimulated, the number of eggs reaches ten to fifteen. To remove an egg, it is necessary to puncture the follicle (microtrauma).

  • Embryo implantation. Most women whose IVF outcome is successful note the presence of minor pain in the abdomen and lower back. It is known that if the lower back hurts after embryo transfer, this is not associated with spinal pathology. During the first stage of pregnancy, changes do not occur that affect the spine or provoke compression of nerve endings. Lower back pain is “referred” in nature, and the reason for this is gynecology.

  • Increased gas formation. Poor nutrition causes bloating.

  • Oscillations hormonal status.

  • Big uterus. If two or three embryos develop, the uterus increases significantly. The ligaments that support the organ become stretched, causing pain.

When to worry:

  • The pain after embryo transfer is acute and unbearable.
  • Along with the pain, intense bleeding occurs.

These signs are not always an alarm. Symptoms may be due to hormonal changes and poor attachment of the embryo. The doctor will dispel doubts and, if necessary, prescribe treatment.


In any situation, it is advisable to remain calm and follow the doctor’s recommendations: watch the menu, get plenty of rest, take walks in nature. Don't be afraid to ask for help and stop self-medicating.


According to statistics, most women were diagnosed with bleeding after embryo transfer. If painted in pink discharge appeared on the sixth to twelfth day after IVF, then this is implantation bleeding.


Implantation bleeding is early sign the birth of a new life. When implantation of the embryo occurs, the small capillaries of the endometrium are damaged. It is for this reason that minor bleeding occurs.


In clinics specializing in reproduction methods, patients are informed in detail about the consequences of artificial insemination and possible symptoms. Doctors at the IVF Center clinic in Smolensk are ready to provide 24/7 assistance patients after embryo transfer.

The introduction of the embryo into the uterine wall, or its implantation, completes embryogenesis. From this moment on, a fetus is formed from the embryo. This important stage development, on which the successful outcome of pregnancy largely depends.

This process is still little studied, since although the embryo is accessible to scientists (for example, during in vitro fertilization), the process of its penetration into the uterine wall is impossible to see.

In many cases, despite good condition uterus and embryo, its implantation does not occur. This is especially difficult for IVF patients.

Embryogenesis phases

The egg is fertilized in fallopian tube and within 5-7 days it moves along it into the uterine cavity. At this time, it continuously divides, forming cells from which the fruit and its membranes will subsequently develop. The outside of this formation is covered with a protective layer. After entering the uterus, the blastocyst (the so-called formed embryo) must attach to its wall in order to receive oxygen and nutrients from the mother’s body.

On what day does embryo implantation occur after conception?

The embryo enters the uterine cavity 4-5 days after fusion with the sperm. Then it is freed from the outer cells that protected the egg from re-fertilization, and after 1-2 days it penetrates the wall of the organ. Thus, the general time frame for embryo implantation from conception to implantation in the uterus is 6-7 days.

During implantation, the embryo undergoes complex processes, passing from the uterine cavity into its wall. This process is conventionally divided into three phases:

  1. Apposition (attachment).
  2. Attachment.
  3. Invasion (penetration).

After the blastocyst is released from the outer cells, it becomes a freely moving ball. It approaches the surface of the endometrium and attaches to it, despite contractions of the uterine wall and the production of a mucous substance - mucin. This is made possible by highlighting chemicals– cytokines and chemokines that are produced by both the blastocyst and the endometrium.

The production of these substances actively occurs in the first 6 days after ovulation, and in the first phase of the cycle they are practically absent. During the anovulatory cycle, the release of such adhesive substances by the uterus is also minimal.

After the initial apposition, the next stage begins - attachment. It is mediated by integrin receptors on the surface of the endometrium. As a result of their interaction with the embryo, the latter sinks into the wall of the uterus and is “covered” from above by endometrial cells. Integrins in the greatest number present in the uterus immediately after and during the 2nd phase of the cycle. However, their activity is significantly reduced in women with luteal phase deficiency, endometriosis, and infertility unknown origin. In such patients, the blastocyst cannot penetrate the mucous membrane.

At the final stage (10–14 days after conception), the chorion begins to form, which then turns into the placenta. The cells of the embryo dissolve the walls of blood vessels, intermediate tissue and are tightly fixed in the uterine wall.

What happens after the embryo is implanted into the uterus?

At this stage, direct connections are formed between the embryo and the uterine vessels, chorionic villi develop, and joint circulation of the mother and fetus occurs. This embryonic period, which lasts up to 8 weeks. The placenta gradually forms, which begins to function fully from the 20th week of pregnancy.

If the invasion process is disrupted, placental anomalies develop: with deep invasion, placenta accreta is likely, and with superficial invasion, the risk of fetal developmental delays increases.

How long does the embryo implantation process take?

Three successive phases take 2-3 days.

With IVF, all these stages may be somewhat lengthened or shifted in time. Typically, embryos that are 3 and 5 days old are introduced into the uterus. However, their implementation under the mucous membrane can take up to 10 days.

WITH medical point In terms of vision, implantation continues until the placenta is completely formed, that is, until the 20th week of pregnancy. All harmful factors acting at this time on expectant mother, can disrupt the process of placenta formation and cause further deviations in the development of the fetus.

Symptoms

Many women are interested in becoming pregnant and eagerly await signs of successful implantation. They are divided into subjective (feelings), objective ( external changes) and laboratory.

Is it possible to feel the implantation of an embryo?

Yes, during the invasion process the wall of the uterus and its vessels are damaged. Therefore, very light bleeding may occur. Blood is released into minimum quantity, and may go unnoticed.

A woman may feel discomfort in the lower abdomen, pulling or aching pain spreading to the lower back, along inner surface thighs, her temperature rises to 37.5°C.

Other possible sensations during embryo implantation:

  • irritability, drowsiness, weakness;
  • general malaise and fatigue, lack of strength;
  • signs reminiscent of;
  • metallic taste in the mouth and nausea;
  • piercing or cutting pains, mild, reminiscent of itching or scratching.

Most of these symptoms are caused sudden change hormonal levels, in particular, the production of hCG that has begun and is increasing every day. This is a physiological process.

When an embryo is implanted, the discharge may be in the form of a blood smear on the underwear or minor inclusions in the usual discharge from the genital tract. It is not bleeding and does not require the use of sanitary pads. The discharge has no odor or foreign impurities.

All these signs are nonspecific and can be observed with various diseases. Therefore, if they appear, it is advisable to consult a doctor.

To confirm the implantation of the embryo in the uterine wall, hCG testing in urine or blood is used. These tests are repeated if necessary to ensure normal development pregnancy due to an increase in the level of this hormone.

Symptoms of embryo implantation into the uterus are normally mild. If carried out, they may be missing. When intense pain and/or bleeding, you should immediately consult a doctor, as this may be a sign of miscarriage and become life-threatening for the woman.

Self-determination of implantation

Measuring basal temperature will help determine possible implantation if such a procedure is carried out regularly, for 6 or more cycles. In the first phase of the cycle, the temperature in the rectum is low, about 36-36.5°C. At the moment of ovulation it sharply increases to 37°C. If the cell released from the ovary has been fertilized and the embryo has implanted into the wall of the uterus, upon implantation of the embryo, the basal temperature will briefly (literally within 1 day) decrease by 1-1.5°. This usually occurs 6-12 days after ovulation. This phenomenon is called implantation retraction and with great accuracy confirms the implantation of the embryo into the uterine wall.

In the following days, the temperature in the rectum will increase again and will remain within 37°C for the next 3 months. This is due to high level progesterone, which is produced by the corpus luteum of pregnancy.

If, after a sudden decrease in the second phase of the cycle, the temperature does not rise again, this will indicate a lack of consolidation of the embryo or termination of pregnancy.

- a fairly accurate way to recognize ovulation and embryo implantation. It is used not only in the routine practice of gynecologists, but also after in vitro fertilization. IN the latter case The information content of this method is lower, because a woman’s body is under the influence of hormones.

Violations of the embryo implantation process

In some cases, the fertilized egg becomes ready to be implanted into the uterus earlier than necessary. Early implantation of the embryo occurs, ending in most cases. The embryo is freed from the outer cells and attaches to the wall of the tube, without having time to pass into the uterus. This usually occurs 4-5 days after fertilization or 6-7 days after ovulation.

While developing, the embryo maintains its existence corpus luteum pregnancy in the ovary. Then, due to the thin walls of the tube, the destruction of its vessels by the growing fertilized egg, the latter is rejected, the level of hormones drops, the mucous membrane of the uterus separates and comes out.

If the embryo still managed to get into the uterus, its walls are not yet ready to accept it, so it is expelled out, and pregnancy does not occur.

Late implantation is observed 10 or more days after fertilization and is often accompanied by moderate bleeding, which women mistake for regular menstruation. Magnification helps to diagnose pregnancy with late embryo implantation. hCG level. Late implantation of the embryo can be observed during in vitro fertilization.

Despite good ovarian activity and regular fertilization of eggs, embryos may not implant into the uterine wall, resulting in infertility. Why embryo implantation does not occur:

  • the thickness of the uterine mucosa is too thick (more than 13 mm);
  • low levels of progesterone in the blood, which is necessary to delay menstruation and maintain pregnancy (read about the causes of deficiency below);
  • lack of nutrients in the blood and, accordingly, in the endometrium;
  • genetic disorders that cause the inability of cells to divide and the death of the embryo at an early stage;
  • disorders of hemostasis, that is, increased blood clotting, leading to poor supply nutrients implanting embryo;
  • malformations of the uterus, for example, synechiae (intracavitary adhesions);
  • fragmentation of sperm DNA, leading to the impossibility of normal division of the fertilized egg.

After IVF, the implantation of the embryo does not occur for the following reasons:;

  • diet or fasting;
  • prolonged stress, leading to disruption of the regulation of the entire hormonal system of a woman through its effect on the brain, hypothalamus and pituitary gland;
  • diseases of the pituitary gland accompanied by insufficient production gonadotropic hormone.

    • Preparation for implantation

    To increase the likelihood of pregnancy, every woman, after consulting a doctor, can take prenatal vitamins, medications folic acid, vitamin E.

    During IVF, reproductologists include special drugs in the patient’s management regimen for better implantation embryo:

    • gestagen derivatives;
    • Heparin or its low molecular weight forms;
    • Aspirin and others.

    For the successful development of pregnancy, the psychological comfort of the patient, especially those awaiting implantation, is important. Therefore, it is permissible to use herbal sedatives– motherwort, mint, lemon balm, which can be brewed and added to weak tea. During this period, it is recommended to give up caffeine, alcohol, smoking, and taking medications without a doctor’s prescription.

    Must be observed simple rules, increasing the likelihood of normal implantation of the embryo:

    1. Set up good sleep, if necessary, rest during the day.
    2. Eat more fruits, vegetables, dairy products.
    3. Limit salted, smoked, fried foods.
    4. Refuse to visit the solarium and avoid being in the sun.
    5. Do not engage in sports or other strenuous physical activity.
    6. Provide emotional peace and good mood.
    7. Abstain from sexual activity for a while.
    8. Avoid contact with sick people acute infections, do not visit crowded places, do not travel on public transport.

    Many women who have undergone fertility treatment often complain that their stomach hurts after IVF. The IVF method means that the embryo, which was previously fertilized by a donor or spouse, is already in the uterus. Both the embryo itself and the environment where it is located are very small, so you shouldn’t be too surprised if the embryo leaks back or falls out. Such in vitro fertilization is a lifeline for those who suffer from infertility and, accordingly, cannot have children.

    The IVF program refers to fertilization through embryo transfer. During this procedure, the egg remains in the uterine cavity and if you follow all the doctor’s recommendations, which means bed rest for ten days, the embryo will attach to the mucous membrane and implant there. But it also happens that ovum moves from the uterus to another place, and the woman eventually begins to feel pain in the abdomen. In this case, you should consult a doctor immediately.

    Women who have undergone IVF are strongly recommended to observe bed rest for ten days, avoid overheating in every possible way - visiting the sauna and bathhouse, taking a hot bath, if necessary, take a laxative, avoid in every possible way electromagnetic radiation– computers, cell phones and other equipment, as well as avoid stressful and conflict situations. Doctors recommend adhering to a calm lifestyle, taking any position comfortable for the woman, measuring the temperature as often as possible and recording it in a special chart.

    After embryo transfer, your stomach may hurt due to: poor nutrition, as well as non-compliance with the doctor’s recommendations. Your nutrition during this period is very important, so you should watch it, and your diet should include foods rich in proteins. Food should be non-greasy and boiled (beef, veal and white chicken), fermented milk products, steamed cutlets and not fatty fish. It is recommended to drink fruit juice, jelly, rosehip tea and green tea, juice.

    Abdominal pain after embryo transfer may occur if the woman sex life, lift heavy objects, exercise, catch a cold, or take medications without notifying your doctor. It is prohibited to drink alcohol, drink coffee and soda, smoke, or eat large number fruits that can cause allergies. You should not eat fatty and spicy sauces, eat a lot of chocolate, chew gum, and also eat fatty sausages, meats, smoked meats and canned food. It may seem to you that there is absolutely nothing to eat, since nothing is allowed, but in fact, just replace your regular diet with steamed, boiled and fermented milk products nutrition.

    It happens that at this moment you are nervous. So it's best to take a sedative. If you can’t lie down, can’t sit, and have dark thoughts about the future, then you better relax. After all, excitement releases bioactive substances and adrenaline that can disrupt the internal balance of your body and significantly reduce the chance of implantation.

    Should be used for calming by simple means– regular valerian in the form of a decoction or tablets, motherwort or other soothing herbs. Here are the various sedatives It is better not to take them, as they affect the internal balance of the body, and this can be fraught with consequences.

    Forget about sexual activity at this time, since penetration can be unpleasant and sometimes even painful, and friction will affect the condition of the ovaries.