Sinusitis

The effect of Lyoton ointment on varicose veins. Lyoton gel - a preparation for external use Lyoton foot cream

Symptoms of varicose veins occur in every third person on the planet. Heaviness and pain in the legs, swelling, spider veins - all these are unpleasant signs of problems with blood circulation and elasticity of the veins.

Among all the means of preventing and combating the symptoms of varicose veins, Lyoton gel (manufactured by the pharmaceutical concern BERLIN-HEMIE) is perhaps the most effective.

According to reviews from patients and doctors, Lyoton is quickly absorbed and has a long-lasting anticoagulant effect.

Briefly about the composition and principle of action of Lyoton gel

The active ingredient of the gel is heparin, which prevents blood thickening and clotting. Thanks to its light gel structure, Lyoton is easy to apply and absorbs almost instantly.

Heparin thins the blood, thereby reducing the load on the veins and blood vessels, resulting in a feeling of lightness in the legs.

With long-term use, Lyoton gel has therapeutic effect to dilated veins, and small spider veins completely disappear.

Lyoton is also prescribed for the treatment of bruises, contusions and sprains, as it relieves blood pressure around injured tissue and accelerates the healing process.

The gel is available in packages of 30, 50 and 100 grams. Approximate cost in pharmacies from 300 to 800 rubles depending on the volume.

To many, the cost of the drug seems too high, especially if there is a need to use the gel constantly. In this case, most often you have to select a more or less suitable analogue.

Fortunately, in Russian pharmacies enough ointments that can be used if necessary replace Lyoton gel, it is only important to choose the right product.

Why pay more - a review of cheap analogues

Trombless gel

It is produced in Russia and is an exact substitute for Lyoton gel - this drug contains exactly the same amount of heparin (1000 units).

Accordingly, the indications for use of this drug are the same - soft tissue injuries, varicose veins veins, thrombophlebitis. Trombless quickly and effectively relieves swelling and eliminates the feeling of heaviness in the legs.

Trombless gel is available in packages of 30 and 50 grams. The approximate cost of one package is 200 and 300 rubles, respectively.

Heparin ointment

The closest analogue of Lyoton gel. The active substance, as the name suggests, is heparin. Accordingly, the drug is used in cases where there is a need to thin the blood - varicose veins, thrombophlebitis, hemorrhoids, edema, injuries.

In addition to heparin, the ointment contains benzocaine, a mild pain reliever. local action. Accordingly, for injuries this remedy is even better suited than Lyoton.

However, you need to keep in mind that Heparin ointment contains only 100 units of active substance (heparin), while Lyoton gel contains 1000 units, i.e. 10 times more.

This means that in order to achieve a positive therapeutic effect, you will need more ointment than gel.

Heparin ointment is available in 25 gram packages. The approximate cost of one package is 60-80 rubles.

Troxerutin gel

Technically not complete analogue Lyoton, because active substance The drug is different - not heparin, but the venotonic troxerutin (flavonoid rutin).

However, the effect of this gel is similar to the effect of Lyoton, so it can be used for varicose and traumatic edema, as well as for thrombophlebitis.

Troxerutin improves the elasticity of the veins, thereby facilitating blood flow and relieving the feeling of heaviness in the legs.

Troxerutin gel is available in 40 gram packages. The approximate cost of one package is 30-90 rubles (depending on the manufacturer).

Gepatrombin gel

Quite a good analogue of Lyoton. The active ingredient in this drug is the same - heparin. Accordingly, Gepatrombin is prescribed when venous insufficiency, thrombophlebitis, as well as for the treatment of injuries.

The auxiliary components of this gel - D-panthenol and allantoin - promote rapid regeneration of tissue cells.

Compared to Lyoton, the heparin content in this drug is approximately 3 times less (300 units), i.e. To achieve a similar effect, you need to apply it in more or more often than Lyoton.

Gepatrombin gel is produced in 40 gram packages. The approximate cost of one package is 150-210 rubles.

Memo - instructions for use of Lyoton gel and its analogues

Lyoton gel is a drug for strictly external use. It is applied locally to areas of post-traumatic or hemorrhoidal edema, to spider veins, to areas of enlarged veins.

A small amount of gel (about 2-3 centimeters) light movements rub into the affected area until completely absorbed.
There is no need to wash off the residue.
The procedure must be repeated 2-3 times a day until the symptoms disappear.

Analogues are used according to the same scheme - applied locally. Since Hepatrombin and Heparin ointment have a denser texture, they need to be rubbed in a little longer than Lyoton (about 3-5 minutes), the remnants of these ointments can be removed with a clean napkin.

Gel Trombless and Troxerutin are absorbed as quickly as the original.

Gel Lyoton and its analogues should never be applied to open wounds. Also, analogues (except for Troxerutin) cannot be used for poor blood clotting.

When taking aspirin or other blood thinning drugs, as well as during menstruation in women, before using Lyoton and its analogues, you should consult with your doctor.

The medicine gel Lyoton-1000 received wide application in the treatment of conditions associated with rapid blood clotting. It is used in therapy, to remove bruises and bruises, and to prevent the formation of blood clots.

How does the drug work when various states and how to apply it correctly in practice?

General information

Lyoton-1000 has proven its effectiveness in the prevention of blood clots, in the fight against and in the treatment of conditions of rapid blood clotting

The action of the drug is based on the substance “heparin”, which is part of its composition, which is normally excreted by the kidneys in the human body. The active substance prevents the formation of blood clots and, when entering the human blood, accelerates the action of the protein against rapid blood clotting.

Penetrating through the skin, heparin spreads through the blood and organs and has the following effects on the body:

Increases blood flow in the kidneys;
Prevents the formation of blood clots;
Reduces the risk of blood clots;
Eliminates growths on the skin;
Increases vascular resistance;
Reduces the risk of occurrence.

The ointment is not quickly absorbed into the skin - after applying the gel, heparin enters the bloodstream only after 8 hours. After this, the active substance remains in the body for another 24 hours, after which it is excreted in the urine.

Important! For pregnant and nursing mothers, it is very important that the gel is excreted along with urine, without passing into breast milk.

Application of the gel:

Prevention and treatment;
Edema of the lower extremities;
Injuries, fractures, bruises, sprains;
Varicose veins, spider veins on the face and legs;;
Tumors and lumps on the extremities of a non-infectious nature;
Complications of vein operations;
Formation of hematomas under the skin (bruises).

Lyoton-1000 gel is often used as an analgesic that can relieve pain in the legs when standing and walking, heaviness and fatigue in the lower extremities, and itching in the blood vessels.

Directions for use and dosage

The course and duration of treatment should be determined strictly by the doctor, while the gel itself is used only externally (i.e. it is strictly prohibited to apply it to open wounds)

The gel is used only externally - it is applied to damaged areas of the body as prescribed by a doctor, who determines the dosage of the drug and the duration of the course of treatment.

Application of Lyoton gel according to the instructions:

For abrasions and bruises– apply the drug in a circular, gentle motion to the damaged area of the skin;
For open wounds and ulcers– the medicine is applied to the skin around the wound;
At– the gel is applied to a bandage, which is placed on the damaged area;
At– a cotton swab is dipped into the gel and then placed in the anus.

Typically, the drug is applied in a layer of one to three centimeters about three times a day. The drug is quickly absorbed and therefore does not leave greasy stains on clothes, which makes it very convenient to use.

When using Lyoton gel, the course of treatment can last from one to four weeks, depending on the diagnosis:

For injuries, bruises and swelling the gel is applied until the damage completely disappears 1-3 times a day;
For varicose veins (initial stage diseases), for burning in the veins, heaviness in the legs, to eliminate vascular network the drug is used from one to three weeks.
For chronic venous insufficiency you should use the gel for at least a month (in some cases – up to 6 months).

The drug most often does not cause side effects. Only too long use of the gel can cause some allergic reactions in the form of redness, itching and excessive dryness. skin. If they appear, you must stop using the drug and eliminate negative effects using regenerating lotions and creams.

Cases of overdose when using the gel were not observed, because it cannot be applied too much due to the low absorption of the drug.

Important! If the gel accidentally gets on your mucous membranes, you should immediately rinse them with water. If a child accidentally ingests the gel, he should quickly induce vomiting and rinse the stomach.

You cannot use Lyoton gel:

In case of intolerance or allergy to the components of the drug;
If there are existing blood clotting disorders;
For diseases that cause heavy bleeding;
In the presence of purulent processes;
During menstruation;
When threatened;
In the treatment of phlebitis;
After recently transferred operations on the brain, eyes, bile ducts.

Lyoton gel can be used during pregnancy only with the permission of a doctor, because There are cases of spontaneous after using the drug.

Pay attention! The gel cannot be used if the integrity of the skin is damaged - on open ulcers, wounds.

The medicine is often used in complex therapy in the treatment of varicose pathologies. Therefore, you should consult your doctor before using it - if other drugs that affect the state of the blood (, etc.) are used at the same time, then heavy bleeding is possible.

How can I replace Lyoton gel?

Lyoton-1000 does not cost too little, so searching for analogues is a completely reasonable decision, but the main thing is not to forget about real reviews

Gel Lyoton has a lot of advantages - it acts quickly, short terms shows effectiveness, has practically no side effects and contraindications. But some patients have doubts about using the drug when they find out how much it costs.

Average price(Moscow):

Tube 30 g – 300-400 rubles;
Tube 50 g – 400-460 rubles;
Tube 100 g - about 600-700 rubles.

From inexpensive analogues Lyoton there are domestically produced drugs: Heparin ointment, Heparin, Heparin-Acrigel. For example, heparin ointment can be bought much cheaper (from only 35 rubles), but it has a number of disadvantages compared to Lyoton: the ointment cannot be used on the face and it is poorly absorbed and leaves marks on clothes.

Structural analogues of Lyoton: Trombless, Heparin-Acrigel-1000, Laventum.

Substitutes similar in mechanism of action: Dolobene, Venolife, Contratubeks.

It is difficult to determine how effective analogs of the drug are compared to the Lyoton gel itself, because each drug is selected for treatment certain disease on an individual basis. Therefore, the decision to appoint medicine should be trusted to a doctor.

Included in Lyoton as active substance included heparin sodium at a concentration of 1000 IU/gram.

The auxiliary components of the gel include: methyl and propyl p-hydroxybenzoate, neroli and lavender oils, carbomer 940, triethanolamine, ethanol, purified water.

Release form

The dosage form of the drug is a gel for external use. The product is an almost transparent, colorless or slightly yellowish, viscous mass.

Lyoton 1000 gel is sold in aluminum tubes of 30, 50 or 100 grams.

Pharmacological action

Antithrombotic , anti-exuential , moderate anti-inflammatory .

Pharmacodynamics and pharmacokinetics

When applied to the skin, Lyoton gel relieves puffiness and eliminates increased permeability vascular walls and prevents the release of fluid (exudate) into adjacent tissues, stops inflammatory process, inhibits the activity of the blood coagulation system (has an anticoagulant anticoagulant effect).

After using the drug detected over the next 24 hours, with plasma concentrations reaching maximum values in 8 hours.

Excretion of the substance and its metabolites carried out mainly kidneys . When applied to skin heparin does not affect parameters hemocoagulation .

Indications for use

Ointment Lyoton 1000 is recommended for use in diseases superficial veins , including complicated phlebothrombosis (a condition that is associated with the formation in the lumen of the vein fixed to its wall thrombus , partially or completely obstructing the vessel), (which is accompanied by inflammation of the vascular wall and blocking of the lumen of the vessel thrombus ) or superficial periphlebitis (spicy or chronic inflammation vein walls).

It is considered advisable to use Lyoton ointment to eliminate complications caused by surgery on veins , consequences of injuries and sprains capsular-ligamentous and musculotendinous apparatus , damage soft tissue and musculoskeletal system .

The product effectively removes localized tissue swelling , eliminates inflammatory infiltrate, accelerates the resorption of subcutaneous hematoma .

Contraindications

You should not use Lyoton 1000 cream if:

known individual sensitivity to its components;
availability ulcerative and necrotic changes in the skin in areas where the product is intended to be applied;
traumatic violations of the integrity of the skin;
reduced;
thrombocytopenia .

Side effects

Allergic reactions.

Gel Lyoton, instructions for use

The instructions for use of Lyoton indicate that single dose for an adult corresponds to the volume of gel contained in a strip 3 to 10 cm long (depending on the extent of the lesion). After applying the ointment to the skin, rub it in gently with light movements.

Frequency of applications - from 1 to 3 times a day.

According to the instructions for Lyoton 1000, the duration of treatment depends on the indications and severity pathological process.

Overdose

To date, there have been no reports of overdose cases. Since systemic absorption heparin sodium is extremely insignificant, the danger of overdose with local application absent.

If the gel is accidentally swallowed, a child may experience nausea and vomiting. To help the victim, the stomach should be rinsed and, if necessary, symptomatic treatment should be prescribed.

The antidote is protamine sulfate .

Interaction

Application heparin in combination with anticoagulants for oral administration may cause prolongation of prothrombin time.

Lyoton should not be mixed with other drugs for external use.

It is contraindicated to prescribe the drug in combination with NSAIDs, tetracycline antibiotics , antihistamines .

Terms of sale

Over the counter.

Storage conditions

Best before date

The product is considered suitable for use for 5 years after the date of issue.

Special instructions

The gel contains methyl and propyl p-hydroxybenzoate as auxiliary components, therefore Lyoton is contraindicated in persons with known parabens .

In patients with hemorrhagic symptoms the feasibility of using the product should be carefully considered.

The drug should not be used for bleeding or skin lesions. purulent process, apply to infected areas of the skin and open wounds, mucous membranes, skin around the eyes. It is also necessary to avoid getting the gel in the eyes.

For patients with disorders hemocoagulation It is not recommended to treat large areas of the skin with the drug. During treatment phlebitis , it is contraindicated to rub the ointment into the skin.

Since experience with Lyoton in children is limited, the drug should not be prescribed for the treatment of this category of patients.

The drug does not affect the ability to drive vehicles and does not slow down mental and motor activity.

Analogs Lyoton 1000

Level 4 ATX code matches:

The group of drugs with similar mechanisms of action include: Forte , Venabos , Trombless Plus , .

Russian analogues of Lyoton: Heparin , Heparin-Acrigel , Heparin ointment .

The price of analogues is from 35 Russian rubles(purchase of a tube of Heparin ointment 25 g produced Russian company JSC "Biosintez" will cost approximately 35-60 rubles).

Lyoton or Heparin ointment?

Gel and its analogue Heparin ointment - these are straight lines anticoagulants . Their main mechanism antithrombotic action associated with suppression thrombin .

Sodium salt heparin , which is the active component of Lyoton, in the composition Heparin ointment is present in a lower concentration - 100 IU/gram (in Lyoton its concentration in one gram of the product is 1000 IU). However, in addition to heparin sodium V Heparin ointment also contains (local anesthetic wide range actions) and antiplatelet agent benzyl nicotinate .

Assessing the effectiveness of both drugs, patients note that the effect of their use is expressed approximately equally, therefore, for many, when choosing a drug decisive factor becomes the price - Heparin ointment much cheaper than its counterpart.

Lyoton during pregnancy

Gel Lyoton during pregnancy and during the period breastfeeding(lactation) is allowed to be used only for strict indications.

Typically, pregnant women are prescribed to use the drug throughout the entire period of pregnancy (and sometimes after the birth of the child) in courses according to the scheme: a month of use, a month of break.

Caution should be exercised when first applying the product, as during pregnancy the body becomes more susceptible to allergens , and the probability of occurrence allergic reactions increases.

Therefore, if treatment is accompanied by such unpleasant symptoms such as itching, redness of the skin, burning, etc., you should stop using the drug and consult a doctor.

As for reviews of the use of Lyoton by pregnant women, they are very diverse. Some did not see results even after several months of treatment, while others, on the contrary, noted high efficiency medicines.

Reviews about Lyoton 1000

Reviews about Lyoton 1000 gel are mostly positive, as can be judged by the fairly high rating of the product on specialized Internet resources - 4-4.5 points out of 5.

Thanks to high concentration heparin ointment prevents the appearance spider veins , relieves heaviness in the legs, eliminates swelling and pain, is effective for bruises and sprains. Many women see the drug as practically the only salvation for tired legs after a whole day on their feet (and often in high heels).

Very often, the drug is prescribed to pregnant women, since during pregnancy the likelihood of problems associated with pregnancy increases significantly.

During pregnancy - reviews are eloquent confirmation of this - Lyoton effectively fights stagnation venous blood , prevents the occurrence thrombophlebitis And severe swelling, improves the tone of vascular walls, relieves fatigue.

Negative reviews about the gel are due to the fact that after quite long-term use Patients were never cured with this drug varicose veins or notice obvious improvements in the condition of your legs.

Commenting on such statements, experts never tire of repeating that Lyoton does not cure, but is only a supporting agent, the use of which allows to slow down the progression of the pathological process and prevent the development of its complications.

For the effect of using the cream to be noticeable, treatment should be supplemented with wearing compression hosiery, contrast shower for legs, swimming, hiking.

It is equally important to stop crossing your legs, instill in yourself the habit of regularly resting your feet (at least try to keep them in an elevated position more often), and give preference to comfortable shoes.

You can also often find them on the Internet positive reviews about Lyoton when used on the face. Despite the fact that the main indication for use is venous diseases, the range of use of the drug is much wider.

For the face, the gel is indicated as a decongestant, firming, toning and refreshing agent. Some women even use it as a base for makeup, and plastic surgeons and cosmetologists often recommend ointment to normalize the condition of facial skin after a series of beauty procedures or, for example, blepharoplasty.

Price of gel Lyoton 1000

Price Lyoton 1000 in Ukraine

Price of Lyoton gel in Kharkov, Kyiv and others major cities Ukraine differs slightly.

The price of the ointment produced in 30 g tubes is from 90 UAH. You can buy a 50 g tube of cream for an average of 160 UAH.

How much does the gel cost in Russian pharmacies?

The cost of the drug depends on the volume of the tube. Buying a 30 g tube will cost approximately 350 rubles. The average price of Lyoton in 50 g tubes is 450 rubles, in 100 g tubes - 700 rubles.

Lyoton ointment is used to relieve symptoms of heaviness in the legs, swelling, and blocked veins. The drug is prescribed as part of complex therapy for the treatment of chronic and acute vascular pathologies. As a mono-medicine, it is effective for swelling and bruising due to soft tissue injury.

An external venotonic agent is available in aluminum tubes with a volume of 30-50-100 g.

The main component of the ointment is sodium heparin. The content of the substance in 1 g corresponds to 1000 IU. Lyoton has a jelly-like, yellowish consistency that is easily absorbed into the skin.

Properties of Heparin - reducing blood viscosity, restoring connective tissue.

For external use:

has a restorative effect on subcutaneous traumatic hemorrhages (bruises, hematomas);
promotes the dissolution of blood clots;
increases capillary permeability;
prevents blood thickening during venous stagnation.

Additional ingredients in Lyoton:

parabens (methyl-, propyl-);
Carbomer;
ethanol:
water;
lavender oil, neroli;
Triethanolamine.

Methyl parahydroxybenzoate and Propyl parahydroxybenzoate are preservatives, Carbomer gives the ointment viscosity, Triethanolamine is an oil emulsifier. The aroma of lavender and neroli oils neutralize the specific smell of benzoic acid and Heparin preparations.

Indications for use

Lyoton 1000 is useful for prolonged static loads on lower limbs, which is associated with the performance of professional duties: sedentary work while standing, lifting heavy objects. Hereditary weak venousness (insufficient functioning of venous valves) is also compensated by the use of the drug Lyoton.

Attention! The ointment is used as part of complex therapy for vascular pathologies as a symptomatic remedy to relieve pain.

What it helps with:

with thrombosis with inflammation of superficial venous vessels;
varicose veins of the legs;
inflammation of the vascular walls (periphlebitis);
phlebothrombosis (formation of blood clots in the venous bed);
swelling after a bone fracture, dislocation, sprain;
superficial hematomas;
mastitis;
after vein operations;
soft tissue bruises with bruising;
infected seals.

The composition is applied to clean, dry skin. The individual duration and frequency of administration should be determined by the doctor.

Average values for ointment use (depending on the disease, the degree of vascular damage):

treatment of injuries, bruises - until the bruise completely resolves;
relief of symptoms of venous insufficiency – 21 days, repeated course in a month;
restoration of blood flow during thrombosis as part of complex therapy - 30 days, with treatment continued for a year.

The dose of Lyoton in the instructions for use varies from 3 to 10 cm, which depends on the size of the affected area. The ointment is applied in a thin layer and rubbed into the skin with light pressure. Frequency – from 1 to 3 times a day.

The ointment retains its properties at a temperature not exceeding 25 degrees for 5 years when sealed. After opening the tube, you must use the gel within 30 days.

There are no contraindications for breastfeeding.

The drug has no effect on concentration and reaction speed when administered vehicle, mechanisms of increased danger.

Keep away from children.

Contraindications and side effects

The gel is not used if the skin is damaged:

wounds;
scratches;
ulcers

It is contraindicated to use Lyoton if there are rashes of an allergic or infectious nature, with dermatitis, eczema, or insect bites.

Lyoton has contraindications:

with increased bleeding (reduced blood clotting, insufficient number of platelets).
allergic reaction to the components of the ointment, manifested in the form of itching, rash, swelling;
cirrhosis, hepatitis;
pregnancy with the threat of premature birth.

The drug is prescribed with restrictions:

for bronchial asthma;
arterial hypertension;
elevated blood sugar levels;
inflammation of the heart muscle;
tuberculosis in the active stage;
liver, kidney failure;
patients over 60 years old;
children;
during radiotherapy.

Attention! Simultaneous use other anticoagulants, nonsteroidal anti-inflammatory drugs, antiplatelet agents enhance the effect of Lyoton and may cause increased bleeding.

Reduce the effectiveness of the ointment:

nicotine;
ergot preparations;
Thyroxine;
antihistamines.

External use of the drug has no information on cases of overdose. If Lyoton is swallowed by a child, nausea and vomiting are detected. After gastric lavage, the antidote Protamine sulfate is prescribed in large doses.

Registration number: P N012107/01 dated 09.16.2011

Trade patent name: Lyoton ® 1000

International generic name(INN): heparin sodium

Dosage form: gel for external use

Compound:

100 g of gel contains:

Active ingredient: heparin sodium - 100,000 IU

Excipients: carbomer 940 – 1.25 g, methyl parahydroxybenzoate – 0.12 g, propyl parahydroxybenzoate – 0.03 g, ethanol 96% – 30.00 ml, neroli oil – 0.05 g, lavender oil – 0.05 g, trolamine (triethanolamine ) – 0.85 g, purified water – up to 100.00 g.

Description: Colorless or with a slightly yellowish tint, almost transparent gel of viscous consistency with a pleasant odor.

Pharmacotherapeutic group: anticoagulant direct action for local use.

ATX CODE: S05BA03

Pharmacological properties

Pharmacodynamics

Heparin sodium is a direct-acting anticoagulant that belongs to the group of medium-sized heparins. Prevents thrombus formation, inhibits the activity of hyaluronidase, and activates the fibrinolytic properties of blood.

When applied externally, it has a local antithrombotic, anti-edematous and anti-inflammatory effect, improves blood microcirculation and activates tissue metabolism, as a result of which the processes of hematoma resorption are accelerated, the formation of blood clots is prevented, and tissue swelling is reduced.

Pharmacokinetics

When applied externally, a small amount of heparin penetrates into the systemic circulation without causing systemic action without causing any changes in blood coagulation parameters. Does not penetrate the placental barrier.

Indications for use

diseases of the superficial veins: varicose veins, chronic venous insufficiency and related complications (thrombophlebitis, periphlebitis);

blunt injuries and soft tissue bruises;

subcutaneous hematomas, including hematomas after venous surgery, phlebectomy;

localized infiltrates and swelling of soft tissues.

Contraindications

hypersensitivity to the components of the drug;

violation of the integrity of the skin at the site of application of the drug (open wounds, ulcerative necrotic lesions);

increased tendency to bleeding, thrombocytopenia;

age under 18 years (the safety and effectiveness of the drug have not been studied).

Use during pregnancy and breastfeeding

The use of Lyoton ® 1000 is not contraindicated during pregnancy and breastfeeding.

Heparin does not penetrate the placental barrier and into breast milk. Due to the insignificant absorption of heparin when applied externally, the drug does not have a systemic effect on the body. However, before using Lyoton ® 1000, you should consult your doctor.

Directions for use and doses

For external use.

A small amount of gel (3-10 cm) 1-3 times a day is applied in a thin layer to the skin and rubbed in gently.

For localized consequences of injuries and bruises(hematoma, infiltration, soft tissue swelling) apply until symptoms disappear.

At initial symptoms venous insufficiency(“heaviness”, pain in the legs, venous edema) apply for 1 – 3 weeks depending on the severity of symptoms.

For chronic venous insufficiency(varicose veins, superficial periphlebitis, superficial thrombophlebitis) apply for 4 – 6 weeks depending on the severity of the symptoms of the disease.

Necessity further treatment determined by the doctor.

Side effects

IN in some cases Hypersensitivity reactions to the components of the drug may occur, manifested by redness and/or itching of the skin, which usually disappear after stopping use of the drug.

Overdose

Extremely low systemic absorption active component When used externally, the drug makes overdose almost impossible.

In case of overdose, the effect of heparin can be neutralized with a solution of protamine sulfate.

Interaction with other drugs

With prolonged use of the drug Lyoton ® 1000 on large areas of the skin and the simultaneous use of indirect anticoagulants (warfarin, syncumar, etc.), prothrombin time and blood clotting time should be monitored.

The effect of the drug on the ability to drive vehicles and operate machinery

Lyoton ® 1000 does not affect the ability to drive vehicles or work that requires increased concentration.

Release form

Gel for external use 1000 IU/g.

30, 50 or 100 g of the drug in aluminum tubes, coated on the inside with epoxy resin, with a screw-on perforator cap (polyethylene/polypropylene).

1 tube along with instructions for use in a cardboard box.

Best before date

Do not use after the expiration date of the drug indicated on the package.

Storage conditions

At a temperature not higher than 25 oC.

Keep out of the reach of children!

Release from pharmacies