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The drugs Diane 35, Duphaston and Remens for polycystic ovary syndrome help to cope with the disease without resorting to surgery. As you know, polycystic ovary syndrome (PCOS) is a common disease of the female genital area, which, along with salpingoophoritis, most often causes problems with conceiving and bearing a child. Polycystic disease usually affects women reproductive age, from 15 to 40 years, but in in rare cases it can also be diagnosed at an older age.

Polycystic ovary syndrome is a disorder in their functioning, in which the ratio of hormones produced changes. For this reason, multiple small benign cysts form on the ovaries, making them look like blackberries. This can be easily seen with ultrasound.

Since hormonal levels are disrupted in polycystic disease, problems with ovulation begin: it either does not occur at all, or comes with a long delay. Therefore, the main manifestation of this disease is cycle disruptions.

In the body healthy woman with stable hormonal levels by the middle of the cycle (usually on the 14-16th day) a corpus luteum, the follicle matures and the egg “breaks out” into abdominal cavity- ovulation occurs. With polycystic disease, the follicles may mature, but the corpus luteum does not form, and under the influence of excessive testosterone production, follicular regression begins. Therefore, ovulation does not occur in to the fullest or doesn't happen at all.

Symptoms

A woman's normal monthly cycle is 21-35 days. With polycystic disease, these numbers increase significantly and can reach 40-60 days, that is, menstruation can come once every 2 months. In addition to this most obvious symptom, the following manifestations may be observed:

  • acne (acne), especially in the chin area. If puberty long gone, but acne does not disappear - this is a reason to check the ovaries for the presence of polycystic disease and donate blood to determine the amount of hormones;
  • androgynous hair loss (alopecia) on the head and increased hair growth in other places, for example, on the chin, above the upper lip;
  • excessive oily skin in itself may not indicate the presence of polycystic disease, but in combination with other signs it is a reason to consult a doctor;
  • being overweight often causes hormonal imbalance, which provokes polycystic ovary syndrome;
  • secretion of milk from the mammary glands in the absence of pregnancy and small children (galactorrhea);
  • spotting before the start of menstruation and for several days after it ends. At the same time, the periods themselves can change their intensity: be scanty or, conversely, excessively abundant;
  • problems conceiving a child or repeated miscarriages. It is in this case that women go to the doctor, after which they are diagnosed with polycystic ovaries.


Reasons

The main cause of polycystic disease and hormonal imbalance is not always possible to accurately determine. There can be many factors that provoke the disease; those at risk include:

  • women with a history of type 2 diabetes;
  • obese. Moreover, under obesity in this case This does not mean some situational excess weight due to stress or other unfavorable circumstances, but obesity in the form of a disease that could appear in adolescence;
  • some doctors believe that polycystic disease can lead to chronic inflammation throat tonsils (tonsillitis);
  • disorders of the adrenal glands;
  • tumors of the pituitary gland, ovaries;
  • chronic in the pelvic organs, in the absence of timely and qualified treatment, can be one of the causes of hormonal imbalance and, as a complication, cause polycystic ovaries.

Diagnosis of the disease includes ultrasound examination(ultrasound) of the ovaries, as well as blood for the ratio of hormones: progesterone, testosterone, globulin, estradiol, luteinizing and follicle-stimulating hormones and others (at the discretion of the doctor). If a history of polycystic ovary syndrome is detected, then hormonal drugs are prescribed to correct hormonal levels.

Remens for polycystic ovary syndrome

A homeopathic medicine that is not directly a remedy for polycystic disease, but contains complex therapy is able to regulate the menstrual cycle and restore its course. Available in the form of drops and tablets and taken 3 times a day for at least three months. If necessary drug therapy may be extended.

The good thing about this drug is that it has virtually no side effects. Since the composition is completely herbal, allergic reactions are possible.

Remens is strictly prohibited for pregnant and lactating women, as well as patients who have alcohol addiction or drink regularly. This is due to high content alcohol (43%). If during treatment there is pain in the upper abdomen, nausea, vomiting, general malaise, or change in the color of urine, the woman should stop taking the drug and be examined by a doctor.

Duphaston for polycystic ovary syndrome

The hormonal drug is prescribed for initial stage diseases in cases where a lack of progesterone is detected.

This “female” hormone affects the maturation of the egg, as well as the elasticity of the uterine endometrium, which is very important during pregnancy.

Unlike other hormonal drugs, it is not necessary to start taking Duphaston on the first day of your period. It is usually prescribed on the 10th, 14th or 16th day of the cycle (one tablet per day). On the 25-27th day, they stop taking it, since menstruation comes during this period, then take a break until it ends, and start taking it again.

Treatment of polycystic ovary syndrome with Duphaston leads to complete normalization monthly cycle, reduction pain during menstruation. Also, this drug is able to reduce the amount of estrogen hormones, which in excess can cause tumor formations of the female genital area, as well as endometriosis of the uterus and ovaries.

Duphaston does not cause weight gain, so it can be prescribed if you are already overweight.

Utrozhestan

This is an analogue of Duphaston plant origin, which, in addition to replenishing the lack of progesterone, reduces the concentration of androgens.

Utrozhestan produces light sedative effect, therefore, in case of overdose, it can cause drowsiness. Contraindications to taking the drug are thromboembolic disorders (thrombosis of various origins, heart attack, stroke), oncological diseases and individual intolerance to components.

The drug is available in capsules that can be used either orally (orally) or as vaginal suppositories. Vaginally prescribed only for complete absence progesterone, when the ovaries practically do not work.

Diana 35 with polycystic ovary syndrome

An antiandrogenic drug that is also a contraceptive. Helps with polycystic disease, which is caused by excess androgens. The drug should be taken in the same way as most oral contraceptives: one tablet at a time, starting on the first day of the cycle and ending on the 21st. Then you should take a break for 7 days, after which you should start the next course.

Siofor for PCOS

Unlike previous medications, Siofor is not a hormonal drug in the traditional sense. This is metformin, a sugar-containing hypoglycemic agent prescribed for diabetes mellitus and capable of replenishing the lack of insulin, due to which excessive amounts of “male” hormones are produced.

Metformin Siofor for polycystic disease is prescribed only if disturbances in ovarian function are caused by diabetes mellitus.

An analogue of Siofor is Glucophage. This is another metformin prescribed for type 2 diabetics. Glucophage for PCOS is taken according to the following regimen: in the first days of treatment, 500-800 mg is prescribed 3 times a day. After a week of treatment, the dose may be increased.

Metformin for polycystic disease is not prescribed by all gynecologists, so when diagnosing, you should definitely warn your doctor about the presence of diabetes mellitus.

Clostilbegit for polycystic disease

This is a hormonal drug, the indications for use of which directly indicate polycystic ovary syndrome, lack of ovulation, amenorrhea, and androgen deficiency.

Clostilbegit has quite a few contraindications. These include renal and liver failure, cysts of any origin (except polycystic disease), tumor formations of the pelvic organs and pituitary gland, lactose intolerance, endometriosis, etc. Clostilbegit can impair visual acuity, so during treatment they should avoid driving.

Treatment begins on the 3rd or 5th day of the cycle, depending on the arrival of ovulation, if menstruation occurs, but not regularly. If they are completely absent, you can start taking Clostilbegit any day.

To avoid ovarian hyperstimulation, the initial dose of the drug should be minimal, no more than 50 mg per day. The duration of treatment is determined individually, depending on blood counts.

Inofert and PCOS

It is not a hormonal drug and contains B vitamins, including folic acid. Its main component is vitamin B8 (Inositol), which is capable of changing some hormonal parameters, in particular reducing the levels of luteinizing hormone, testosterone and prolactin in the blood.

Folic acid plays the role of a “stimulator” of the ovaries, therefore Inofert is prescribed for polycystic disease and in complex therapy for the treatment of infertility.

Inofert is available in powder form, which should be dissolved in 150-200 ml of water before use. You need to take one sachet per day for at least a month.

Inofert can be combined with other vitamins and hormonal medications.

Veroshpiron

In general, this drug is a diuretic, but its composition causes the suppression of excess androgen production. Among the side effects, Veroshpiron sometimes causes drowsiness.

It is necessary to take Veroshpiron over a long course, for at least 6 months, 100-200 mg per day. It is necessary to start taking it on the 5th day menstrual cycle and end on the 25th. Then a break is taken and it should be taken again on the 5th day.

Polycystic ovary syndrome is a treatable disease. The list of drugs is extensive, starting hormonal agents and ending with diuretics. The final decision on prescribing any medication is made by the doctor after comprehensive examination and identifying the cause of polycystic disease.

The site provides background information for informational purposes only. Diagnosis and treatment of diseases must be carried out under the supervision of a specialist. All drugs have contraindications. Consultation with a specialist is required!

Marina asks:

Hello! I am 22 years old, I have always had irregular menstruation with delays of 2-3 months, once it happened - it wasn’t even 5 months! I went to the doctors and they prescribed different drugs, vitamins and including Diana 35. Half a year ago, I was diagnosed with polycystic ovary syndrome (dimensions: P - 35X25, L - 32x25) on an ultrasound. They told Diana 35, Virospiron and vitamins according to a special regimen for half a year! I drank all this, BUT MENSTRUATIONS NEVER RECOVERED, we’ve been planning a pregnancy for 2 months - it’s not working out! I went to the doctor again, he gave me a choice: either I’ve been taking Diane 35 for 3 months and trying to get pregnant while withdrawing, or Duphaston and also trying (the doctor didn’t really explain anything to me, and there’s no other option, I live in a village..) What do you advise me?

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Please use the search for answers (The database contains more than 60,000 answers). Many questions have already been answered.

11.10.2004, 14:19

Hello. Tell me if the statement is true long-term use Does estrogen “wash out” folic acid and B vitamins from the body? Perhaps I mixed something up, if so, I'm sorry... I'm just worried, because the doctor has been keeping me on various hormonal drugs: Diane-35, Duphaston, Femoston, Dostinex. Do I need to take extra vitamins? I started having problems with my nerves. It seems like a lack of vit. gr. B can contribute to this. The doctor brushes off my problems, but for six months now I have had insomnia, irritability and a depressed state... Thank you if you can help me.

11.10.2004, 14:31

Sonya, the leaching of vitamins is a kind of synthesis from rumors and the fact of the desirability of taking it, rethought at the everyday level folic acid during pregnancy (without going into details of this desirability)? but I have never seen “holding on Dostinex and Diana + Duphaston” at the same time.
Dostinex is a drug close to ergot alkaloids, and although it is well tolerated, some convulsive twitching may be observed. For what purpose are you taking Dostinex with Diane?
Yes, and on OK so-called. cramps - i.e. convulsive muscle twitching occurs...

11.10.2004, 14:40

No, no, dear Mrs. Melnichenko... Excuse me, I accidentally misled you. Of course, I don’t take all these drugs at the same time... At first I took Dostinex and Diane-35, since I had elevated prolactin and DEA-S, after normalizing the levels of these hormones, I was allowed to get pregnant. We tried for three months on our own. To no avail. Then - two attempts at stimulation-insemination on Clostil and Duphaston. Also to no avail. Now the doctor said that my nerves are no longer good and she “let me rest” for three months on Femoston and Duphaston without protection. She didn't recommend anything sedative to me. I fight like a fish on ice. I understand that the problem is most likely psychological and no medications can help here... But psychotherapists don’t help me much either, telling me things about me that I can reach on my own. And then - a dead end. I'm left alone with myself...

11.10.2004, 15:03


Sonya, if the cause of infertility is only hyperprolactinemia, then Dostinex/parlodel solves the problem in 85% of cases (naturally, NOT together with Diane). If the reason is combined - for example... there is also a male factor, then the situation is solved through combined influences.
I think we have already corresponded. Has hyperprolactinemia been proven to be real?

11.10.2004, 15:14

I won’t speak for the specific process of “washing out” vitamins, but the fact that when taking oral contraceptives there is a lower content of some B vitamins in the blood (cobalamin, pyridoxine) is more likely scientific fact than speculation, as confirmed by a recent major study:

Thromb Res. 2003;112(1-2):37-41. Blood levels of homocysteine, folate, vitamin B6 and B12 in women using oral contraceptives compared to non-users.
Lussana F, Zighetti ML, Bucciarelli P, Cugno M, Cattaneo M.

Does this lead to clinically manifested deficits or does it require replacement therapy- it’s still unclear.

12.10.2004, 06:57

That is, what about femoston and duphaston together?
That's right. Femoston - 28 days of the cycle, and duphaston is added from the 16th to 25th days of the cycle. And so on for three cycles.
Sonya, if the cause of infertility is only hyperprolactinemia, then Dostinex/parlodel solves the problem in 85% of cases (naturally, NOT together with Diane).
Hmm... I don’t even know... I was prescribed Dostinex at the same time as Diane. Yes, Dostinex solved the problem then - prolactin is now normal.

If the reason is combined - for example... there is also a male factor, then the situation is solved through combined influences.
Yes, there is also a male factor, but the reason for the poor spermogram (small volume, small number of motile cells) has not been found. Ultrasound, TRUS, hormones are normal. Now my husband is injected with hCG at 1500 units. twice a week and Sustanon 250 times a month. Treatment for six months. In the first three months, the number of motile sperm increased from 17% to 52%. But attempts at stimulation-insemination remained fruitless. Inseminations were carried out to increase the chances. Stimulation, as I understand it, too.
Stimulation-inseminations are suspended due to my nervousness. And leaving the ovaries “unattended”, i.e. The doctor says it’s impossible without hormonal support. Therefore - femoston-duphaston according to the scheme described above.
The gynecologist does not refer me to a neurologist, because eating something “to relieve my nerves” will be too much for my body... And these drugs can inhibit the maturation of the egg, according to the doctor.
After your messages I am at a loss? Too many hormones? Thank you for your attention to my problem. Yes, we really corresponded with you. I had a slightly different question and our conversation then went away from the problem....

12.10.2004, 07:49

“Nerves” are NOT treated by a neurologist, Diana cannot get pregnant, if prolactin has become normal, then hyperprolactinemia is not the problem, femoston with duphaston “for hormonal support of the ovaries” is something new..-well, this is for Yakov or Tatyana Chebotnikova, in In general, reading your story does not bring a feeling of joyful satisfaction..

12.10.2004, 08:04

“For nerves” it is NOT a neurologist who treats,
And who?

You can't get pregnant on Diana,
This is understandable...

If prolactin has become normal, then hyperprolactinemia is not the problem, femoston with duphaston “for hormonal support of the ovaries” is something new..-well, this is for Yakov or Tatyana Chebotnikova, in general, reading your story does not bring a feeling of joyful satisfaction..
I understand that in this situation you can’t think of a more stupid question... but still: WHAT TO DO? Cancel duphaston in the femoston-duphaston scheme?

12.10.2004, 09:34

Cancel duphaston in the femoston-duphaston scheme?

The doctor prescribed this treatment because, in his opinion, Femoston does not contain enough dydrogesterone (10 mg) for full secretory transformation of the endometrium. By and large, it is not so important whether estradiol and dydrogesterone are prescribed separately or as part of a drug, one or two. What is important is whether there is ovulation or not. If it exists and there is a deficiency in the 2nd phase of the cycle, then such treatment makes sense. If there is no ovulation, then there is little use. To ensure full secretion and increase the number of estrogen receptors before stimulation, it is better to use high-dose COCs (non-ovlon) than drugs for HRT. If stimulation is not planned in the next 1-2 cycles, then one femoston is enough.