How to dilute chloramine. Guidelines for the use of chloramine for disinfection purposes
MINISTRY OF HEALTH OF THE RUSSIAN FEDERATION CENTRAL RESEARCH INDUSTRY OF EPIDEMIOLOGY OF THE RUSSIAN MINISTRY OF HEALTH
Certificate of State registration
No. 77.99.1.2.U.351.1.05
instructions№1
by application disinfectant"CHLORAMINE B"
-PHARM", Russia
(manufacturerBOCHEMIE, Czech Republic)
INSTRUCTIONS
on the use of the disinfectant "CHLORAMINE B",
FARM", Russia (manufacturer BOCHEMIE, Czech Republic)
The instructions were developed by: ILC Research Institute of Virology named after. RAMS, GU TsNIIE MZ RF, -Pharm”, Russia
The instructions are intended for medical personnel medical institutions, workers of disinfection stations, centers of state sanitary and epidemiological surveillance and other organizations that have the right to engage in disinfection activities.
I. GENERAL PROVISIONS
1.1. The product “Chloramine B” is sodium benzene sulfochloramide, available in the form of a white to light yellow crystalline powder with light odor chlorine The content of active chlorine in the product is 25.0% (by volume).
1.2 The product has a shelf life in unopened original packaging. The shelf life of non-activated solutions is 15 days (if stored in a cool, dark place in a closed container).
1.3.Produced in plastic tubs of 350 g, 7 and 12 kg; V plastic bags 12 and 30 kg.
1.4. The product “Chloramine B” has bactericidal effect in from
carrying gram-positive and gram-negative bacteria (including mycobacterium tuberculosis), virucidal action (including pathogens of polio, hepatitis B and HIV infection), fungicidal activity, including pathogens of candidiasis and dermatophytosis.
1.5. The product “Chloramine B” according to the degree of impact on the body according to
Acute toxicity parameters according to GOST 12.1.007-76 belong to class 3 moderate hazardous substances when administered into the stomach, moderately toxic when parenteral administration, low-hazard in terms of volatility (vapor), in powder form has a pronounced local irritant effect on the skin and mucous membranes of the eyes and a weak sensitizing effect.
Working solutions up to 1% (of the drug) with repeated exposures do not cause local irritation, and working solutions of more than 1% cause dry skin, and in aerosol form cause irritation of the respiratory system and mucous membranes of the eyes. MPC rz, for chlorine - 1 mg/m,
1.6. The product “Chloramine B” is intended for:
preventive, current and final disinfection of indoor surfaces, hard furniture, sanitary equipment, linen, dishes, patient care items, toys, cleaning materials, in medical and preventive, children's institutions, in clinical, microbiological, virological laboratories, in outbreaks infectious diseases; at catering establishments, trade, communal facilities (hotels, hostels, baths, laundries, hairdressers, swimming pools, sports complexes, sanitary inspection rooms, etc.);
for carrying out general cleaning in health care facilities and children's institutions; for disinfection of products medical purposes, including dental instruments made of low-carbon steel, nickel-plated metals, rubber, glass, plastics (except endoscopes and instruments for them).
2. PREPARATION OF WORKING SOLUTIONS
2.1. Working solutions of Chloramine B are prepared in enamel, glass or polyethylene containers by stirring the powder in water. For more rapid dissolution"Chloramine B" products should be used in water heated to 30-35° C.
2.2. Non-activated solutions of the product are prepared in accordance with
calculations given in table 1.
Table 1
PREPARATION OF ACTIVATED SOLUTIONS OF “CHLORAMINE B”
Concentration working solution, % | Amount of ingredients (g) required for preparation: |
||
by drug | for active chlorine | 1 liter of solution | 10 l of solution |
2..3.To give cleaning properties to working solutions of the “Chloramine B” product, it is allowed to add synthetic detergents approved for pre-sterilization cleaning of medical devices (Lotus, Lotus-automatic, Astra, Progress) in an amount of 0.5% (5 g/l solution or 50 g/10 l solution) .
2.4. Activated solutions of Chloramine K are prepared by adding an activator (one of the ammonium salts - ammonium chloride, sulfate, ammonium nitrate) to its working solutions. The ratio of the amount of ammonium salt and the amount of active chlorine in the working solution is
2.5. Activated solutions are used immediately after preparation. When preparing activated solutions of Chloramine B, use the calculations given in Table 2.
Table 2
PREPARATION OF ACTIVATED SOLUTIONS OF “CHLORAMINE B”
Concentration solution according to the drug, % | Concentration solution for active chlorine, % | Amount of activator (g) per |
|
1 liter of solution | 1 0 l of solution |
||
3. APPLICATION OF SOLUTIONS OF “CHLORAMINE B”
3.1. Solutions of the product are used to disinfect indoor surfaces (floors, walls, doors, hard furniture, etc.), sanitary equipment, cleaning equipment, linen, tableware and laboratory utensils, toys, patient care items, medical products made from corrosion-resistant metals, glass, plastics, rubbers.
3.2. It is allowed to use solutions of “Chloramine B” with
adding synthetic detergent, permitted for pre-sterilization cleaning of medical products, in an amount of 0.5% (5 g/l of solution or 50 g/10 l of solution). Disinfection of objects is carried out by wiping, irrigation, immersion and soaking.
3.3. Surfaces in rooms (walls, floors, doors, etc.) and (baths, sinks, etc.) are wiped by wiping - 150 ml/m2 of surface, when using a solution with detergent - 100 ml/m2, when irrigated from a hydraulic remote control, automax - 300 ml/m2; from a “Quasar” type atomizer - 150 ml/m2. Upon completion of disinfection, sanitary
technical equipment is washed with water, the room is ventilated until the smell of chlorine disappears.
3.4. Linen is soaked in containers with a solution of the product at a consumption rate of 4 liters per 1 kg of dry linen (for tuberculosis, dermatophytosis - 5 l/kg). The containers are tightly closed with a lid. After disinfection is completed, the linen is washed and rinsed.
3.5. Cleaning equipment is immersed in the product solution, and at the end of the disinfection time, rinsed and dried.
3.6. Dishes freed from food residues are immersed in a solution of the product at a consumption rate of 2 liters per 1 set. The container is closed with a lid. After disinfection is completed, the dishes are washed with water until the smell of chlorine disappears.
3.7. Disinfection of patient care items is carried out by irrigation, wiping or immersion, toys - by immersion in a solution of the product. After disinfection is completed, they are washed with water until the smell of chlorine disappears.
3.8. When disinfecting medical products, they are completely immersed in the working solution of the product, the channels and cavities of the products are filled with the solution using syringes, avoiding the formation of air pockets; detachable products are immersed in the solution in disassembled form. Products with locking parts are immersed open, having previously made several working movements with them for better penetration of the solution into hard-to-reach areas of the products in the area of the locking part. The thickness of the layer of product solution above the products must be at least 1 cm. After disinfection, products made of metals and glass are washed under running water for 3 minutes, and products made of rubber and plastic for at least 5 minutes.
3.9. Disinfection modes with solutions of Chloramine B are given in Tables 3-6.
3.10.In hotels, hostels, clubs and others public places Disinfection of various objects is carried out according to the following regimes: bacterial infections(except tuberculosis) (Table 3).
3.11. In bathhouses, hairdressing salons, swimming pools, sports complexes, etc., when carrying out preventive disinfection, objects are treated according to the regimes recommended for dermatophytosis (Table 6).
3.12. General cleaning in medical, preventive and children's institutions is carried out in accordance with the regimes presented in table. 7.
Table 3
MODES FOR DISINFECTION OF OBJECTS WITH ACTIVATED RAS
CREATIVE MEDICINE "CHLORAMINE B" FOR BACTERIAL INFECTIONS
TSIYAH (EXCEPT TUBERCULOSIS).
Disinfection object | Disinfection time, min. | Disinfection method |
|
Wiping or irrigation Rubbing |
|||
Dinnerware without residues | Dive |
||
Dive |
|||
Linen not contaminated with secretions | Soak |
||
Linen contaminated with secretions | Soak |
||
Dive |
|||
Nursing Items | Dive Rubbing |
||
Medical products made of rubber, metals, plastics, glass, laboratory glassware | Wiping twice or irrigating twice with an interval of 15 minutes. |
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Sanitary equipment | Wiping twice or irrigating twice with an interval of 15 minutes. |
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Cleaning equipment | Dive |
Note: *- with the addition of detergent in the amount of 0.5%
Table 4
MODES FOR DISINFECTION OF OBJECTS WITH SOLUTIONS OF “CHLORAMINE B” FOR VIRAL INFECTIONS (HEPATITIS B, POLIOMYELITIS, HIV INFECTION)
Disinfection object | Concentration of the working solution according to the preparation, % | Disinfection time, min | Disinfection method |
Indoor surfaces, hard furniture | Rubbing |
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Dinnerware with leftover food | Dive |
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Linen with protein contamination | Immersion in excess solution |
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Nursing Items | Immersion, rubbing or irrigation |
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Medical products made of corrosion-resistant metals, rubbers, plastics, glass | Dive |
||
Sanitary equipment | Wiping or irrigation |
||
Cleaning equipment | Dive |
Table 5
MODES FOR DKZIPFUNCTION OF OBJECTS WITH SOLUTIONS OF THE MEDICINE “CHLORAMINE” FOR TUBERCULOSIS (concentration of solutions according to the drug)
Disinfection object | Product solution* | Disinfection method |
|||
not activated | activated |
||||
Solution concentration, % | Disinfection time, min | Solution concentration, % |
disinfection of mines |
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Indoor surfaces, hard furniture | Irrigation or wiping |
||||
Dive |
|||||
Dinnerware with leftover food | Dive |
||||
Uncontaminated linen | Soak |
||||
Soiled laundry | Soak |
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Dive |
|||||
Nursing Items | Dipping or rubbing |
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Medical products made of corrosion-resistant metals, rubbers, plastics, glass, laboratory glassware | Dive |
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Sanitary equipment | Wiping or irrigation |
||||
Cleaning equipment | Environment |
Table 6
MODES FOR DISINFECTION OF OBJECTS WITH SOLUTIONS OF “CHLORAMINE B” FOR DERMATOPHYTIAS AND CANDIDIASIS (concentration of solutions according to the drug)
Disinfection object | Product solutions | Disinfection method |
|||
not activated | activated |
||||
Solution concentration, % | Disinfection time, min | Concentration solution,% | Disinfection time, min |
||
Indoor surfaces (floors, walls, doors, hard furniture, etc.) | Irrigation or wiping |
||||
Tableware without food residues | Dive |
||||
Dinnerware with leftover food | Dive |
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Soak |
|||||
Nursing Items | Dive |
||||
Dive |
|||||
Medical products made of corrosion-resistant metals, rubbers, plastics, glass, laboratory glassware | Dive |
||||
Hydraulic and technical equipment | Wiping or irrigation |
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Cleaning equipment | Dive |
Note: * - disinfection mode for candidiasis
Table 7
MODES FOR DISINFECTION OF OBJECTS WITH NON-ACTIVATED SOLUTIONS OF “CHLORAMINE B” WHEN CARRYING OUT GENERAL CLEANING IN HEALTHCARE AND CHILDREN’S INSTITUTIONS
|
disinfection | Concentration of the working solution according to the preparation, % | Disinfection time, min. | Disinfection method |
|
7.4. Transportation of the product is possible by any means of transport in the original packaging of the manufacturer in accordance with the rules for the transportation of goods that apply to each type of transport and guarantee the safety of the product and container. |
Preparation of a 10% bleach solution and
working solutions (0.5%, 1%, 3%)
Target: Prepare a 10% clarified bleach solution (stock solution).
Indications: disinfection.
Equipment:
1. Gown (long surgical).
2. Rubber apron.
3. Respirator or 4-layer gauze mask.
5. Medical cap.
6. Rubber gloves.
7. Measuring container.
8. Enameled container with a lid.
9. A dark glass bottle with a ground stopper.
10. Wooden spatula.
11. Label.
12. Warm water - 10 liters.
13. Gauze napkin or sieve.
14. Dry bleach 1kg.
15. Ventilated room.
Sequence of actions:
1. Put on a second robe, rubber apron, rubber gloves, respirator or mask.
2. Take 1 kg of dry bleach.
3. Pour it carefully into an enamel container and chop it with a wooden spatula.
4. First add 2-3 liters of water, stirring constantly with a wooden spatula until a uniform suspension is formed, and then add water to the 10 liter mark.
5. Close the enamel container with a lid and leave for 24 hours (during the first 4 hours of settling, you must stir the mixture at least 3 times so that the active chlorine completely goes into solution).
6. After 24 hours, pour the resulting solution, without shaking, through 4 layers of gauze (bandage) into a dark glass bottle marked “10% bleach solution.”
7. Close with a stopper.
8. Put on the label: - the date of preparation of the solution;
His concentration;
Your position and surname.
9. Remove protective clothing.
10. Wash your hands.
11. Lubricate your hands with cream.
Note:
The 10% solution is stored in a dark, cool place;
Use within 5-7 days.
Preparation of working solutions of bleach
from a stock solution of 10% bleach
Example: Take 1 liter of 10% bleach solution and add 9 liters of water - you get a 1% bleach solution.
Application of bleach solutions:
10% - disinfection of secretions and wash waters, for the preparation of all working solutions.
0,5% - for processing dishes and various surfaces.
1% - for treating floors, surfaces, vessels, toilets, bathtubs, etc.
3% - 5% - for disinfection of disposable systems and syringes with their subsequent destruction, debris, purulent dressings.
Preparation of working solutions of chloramine (0.5%, 1%, 3%, 5%)
Before use, working solutions are prepared from dry chloramine, diluting the powder with water in the required concentrations. Water is added to the powder to the desired volume (up to 1 l, 1.5 l, etc.)
Working solutions can be used for 15 days if stored correctly (dark, dry, cool and well-ventilated area).
Preparation of working solutions of chloramine
(BCB) is a white or slightly yellowish powder with a faint odor of chlorine. Contains up to 30% active chlorine. It can be stored at home for years without reducing its activity. Unlike bleach, chloramine does not destroy fabrics and paints.
For use in the form of a solution of 0.2% -10% concentration for disinfection of brushes, tableware, etc.
Preparation of the solution
To prepare chloramine solutions, the following quantities of the drug are required:
Precautions when working with chloramine
When working with chloramine and especially its activated solutions, it is necessary to protect the respiratory system with a RU-60 respirator. The work is performed in a robe, rubber gloves, and an apron. Guidelines developed at the All-Union Scientific Research Institute of Disinfection and Sterilization. The instructions for the use of chloramine for disinfection purposes dated December 24, 1947, from the moment these guidelines were approved, shall be considered no longer in force.
General information
Chloramines include a number of organic compounds, having a common chemical formula RSO 2 NH 2 (R - means radical), in which one or both hydrogen atoms located at nitrogen are replaced by chlorine. A distinction is made between chloramine B, if the starting product is benzene, and chloramine T, if toluene is used for this.
Domestic chloramine used for disinfection purposes is called chloramine B, belongs to the group of monochloramines and has the formula: C 6 H 5 SO 2 N(Na)C1*3H 2 . It represents sodium salt benzene sulfonic acid chloramide, has the form of a white fine-crystalline powder. Typically contains 26% active chlorine, retaining this amount of chlorine for a long time if stored correctly.
Chloramine B is highly soluble in water at room temperature. Its solutions do not spoil or discolor fabrics.
Chloramine has high activity against gram-negative and gram-positive microorganisms, starting from 0.2%. Since active chlorine binds to organic substances, then the concentration of solutions in practical conditions is increased to 0.5-1-2-3-5%. Hot solutions of chloramine have a higher disinfecting effect.
The bactericidal and virucidal properties of chloramine solutions are increased by the addition of ammonium compounds (ammonia, ammonium sulfate or ammonium chloride), which act as an activator. Activated chloramine solutions quickly lose active chlorine, so they are used immediately after preparation.
Chloramine is stored in a dark glass container with a well-fitted stopper or, even better, with a ground-in stopper, in a wooden container or in a tin container coated on the inside with asphalt varnish, as well as in polyethylene bags. When storing chloramine, avoid direct exposure to light and moisture.
Chloramine and solutions prepared from it are checked from time to time for the content of active chlorine in them; This establishes the loss of active chlorine and the correct preparation and storage of solutions.
Find something else interesting:
CHLORAMINE B
Name (Latin)
Composition and release form
It is the sodium salt of benzenesulfonic acid chloramide, available in the form of a white to light yellow crystalline powder with a faint odor of chlorine. The content of active chlorine in the product should be in the range from 24% to 27%. Produced in plastic bags of 100 - 500 g, transport packaging - bags up to 30 kg.
Pharmacological properties
The drug has antimicrobial effect against bacteria (including Mycobacterium tuberculosis), viruses (including HIV) and parenteral pathogens viral hepatitis), fungi of the genus Candida, dermatophytes, pathogens of particularly dangerous infections - anthrax, plague, cholera. According to the parameters of acute toxicity according to GOST 12.1.007-76, it belongs to the 3rd class of moderately hazardous substances when administered into the stomach, moderately toxic when administered parenterally, low-hazard in terms of volatility, in powder form it has a pronounced local irritant effect on the skin and mucous membranes of the eyes and a weak sensitizing effect action, carcinogenic and cocarcinogenic effects have not been identified.
Indications
For disinfection of indoor surfaces, sanitary equipment, linen, dishes, toys, patient care items, medical products, cleaning materials for bacterial (including tuberculosis) and viral infections (including hepatitis with parenteral transmission and HIV infection ) etiology, dermatophytosis, candidiasis, especially dangerous infections (anthrax, plague, cholera) during final, current and preventive disinfection in infectious foci, medical and preventive institutions, children's institutions, at communal facilities, catering establishments, in everyday life, during general cleaning in medical and preventive and children's institutions.
Doses and method of administration
For disinfection - used in the form of non-activated and activated solutions with ammonium salts or ammonia in a concentration of 0.5 - 5%. Working non-activated solutions are prepared by stirring it in water until completely dissolved in accordance with the calculations given in the table:
Note: for faster dissolution of Chloramine B, you should use water heated to 50 - 60 ° C. Activated solutions of Chloramine B are prepared by adding an activator (one of the ammonium salts - ammonium chloride, sulfate, ammonium nitrate, or ammonia) to its working solutions. The ratio of the amount of ammonium salt and the amount of active chlorine in the working solution is 1: 2, and the ratio of ammonia and the amount of active chlorine is 1: 8. Activated solutions are used immediately after preparation. When preparing activated solutions of Chloramine B, use the calculations given in the table:| Solution concentration according to the drug, % | Solution concentration for active chlorine, % | Amount of activator (g) added to: |
|||
| 1 liter of solution | 10 l of solution |
||||
| ammonium salt | ammonia 10% | ammonium salt | ammonia 10% |
||
The time for disinfecting objects with non-activated solutions of Chloramine B for infections of bacterial (except tuberculosis) etiology ranges from 0.5 to 5 hours, depending on the object and the method (wiping or irrigation, immersion or soaking) of disinfection. For household disinfection: dissolve 4 tablespoons (50 g) in 5 liters of water. Use the resulting solution to treat indoor surfaces (floors, walls, doors, etc.). Wipe sanitary equipment (baths, sinks, toilets, etc.) twice with a rag soaked in the solution. Immerse dishes, toys, patient care items, and linen in the solution for 60 minutes. To disinfect linen contaminated with secretions and cleaning material, use a solution prepared at the rate of 2 tablespoons of product per 1 liter of water. After treatment, rinse linens and cleaning materials, wash dishes, toys, and care items with running water until the smell of chlorine disappears.
Side effects
If the rules are followed, no dilutions are observed.
Contraindications
Increased sensitivity to the drug.
Special instructions
Avoid contact of product with eyes and skin. Carry out all work with rubber gloves.
Storage conditions
In a cool, dry, dark place, out of reach of children, away from medicines, food and petroleum products, explosives and flammable substances. Shelf life: 5 years. The shelf life of non-activated solutions is 15 days (if stored in a cool, dark place in a closed container). Activated solutions are used immediately after preparation.
