ethnoscience

Is it possible to use Sofradex? Sofradex drops: instructions for use

Sofradex is a complex drops used in ophthalmology and otolaryngology. Active ingredients: dexamethasone, framycetin, gramicidin.

Ineffective against steptococci. Does not affect pathogenic fungi, viruses, anaerobic flora. Resistance of microorganisms to framycetin sulfate develops slowly.

Gramicidin - has a bactericidal and bacteriostatic effect, expands the spectrum of antimicrobial action of framycetin due to its activity against staphylococci, since it also has an antistaphylococcal effect.

Dexamethasone is a corticosteroid that has a pronounced anti-inflammatory, antiallergic and desensitizing effect. Suppresses inflammatory processes by inhibiting the release of inflammatory mediators, the migration of mast cells and reducing capillary permeability.

Therapeutic effects of Sofradex drops:

When instilled into the eyes, it will reduce pain, burning, lacrimation, and photophobia.
When instilled into the ears, they reduce the symptoms of otitis externa (redness of the skin, pain, itching, burning in the external auditory canal, feeling of ear congestion).

Composition of Sofradex, active substances (in 1 ml):

framycetin sulfate – 5 mg;
dexamethasone (in the form of sodium metasulfobenzoate) – 0.5 mg;
gramicidin – 0.05 mg.

Auxiliary components: phenylethanol (phenylethyl alcohol), sodium citrate, polysorbate 80, lithium chloride, ethanol 99.5%, citric acid monohydrate, water for injection.

Systemic absorption of active substances when applied topically is low.

Indications for use

What does Sofradex help with? According to the instructions, drops are prescribed in the following cases:

bacterial diseases of the anterior segment of the eye (blepharitis, conjunctivitis, keratitis (without damage to the epithelium), iridocyclitis, scleritis, episcleritis);
infected eczema of the eyelid skin;
otitis externa.

Instructions for use of Sofradex, drops dosage

Depending on the indications, drops are instilled into the conjunctival sac of the eye or into the external auditory canal (ear).

Eyes

Standard dosages for eye diseases, according to the instructions for use of Sofradex drops, are from 1 to 2 drops every 4 hours. In severe forms, it is permissible to instill every hour, reducing the frequency of instillations as symptoms decrease.

During instillation, you must be careful not to touch the tip of the pipette to your eye.

Drops should be instilled into the external auditory canal, 2-3 drops 3-4 times a day. You can also place a gauze swab soaked in the solution into the ear canal.

The duration of treatment with Sofradex drops should not exceed seven days.

special instructions

With long-term treatment, there is a risk of developing superinfection caused by resistant microorganisms, including fungi.

With prolonged (more than 7 days) and repeated therapy, it is necessary to regularly monitor intraocular pressure, as well as conduct eye examinations for the development of secondary infections and cataracts.

The drug is prohibited for use in patients with ocular hyperemia of unknown etiology, as this is fraught with significant deterioration of vision.

Side effects

The instructions warn about the possibility of developing the following side effects when prescribing Sofradex:

allergic reactions;
irritation;
burning;
pain;
dermatitis;
increased intraocular pressure with the development of the glaucoma symptom complex (damage to the optic nerve, decreased visual acuity and the appearance of visual field defects), therefore, when using drugs containing glucocorticosteroids for more than 7 days, intraocular pressure should be measured regularly;
development of posterior supcapsular cataract (especially with frequent instillation);
thinning of the cornea or sclera, which can lead to perforation;
addition of a secondary (fungal) infection.

Contraindications

It is contraindicated to prescribe Sofradex drops in the following cases:

increased individual sensitivity to any of the components of the drug;
viral or fungal infections, tuberculosis, purulent inflammation of the eyes, trachoma;
violation of the integrity of the corneal epithelium and thinning of the sclera;
herpetic keratitis (tree-like corneal ulcer) (possible increase in the size of the ulcer and significant deterioration of vision);
glaucoma;
perforation of the eardrum (penetration of the drug into the middle ear can lead to the development of ototoxicity);
pregnancy and lactation;
infants.

Carefully:

pregnancy and lactation;
young children (especially when the drug is prescribed in large doses and for a long time - the risk of developing systemic side effects and suppression of adrenal function).

Overdose

If the contents of one vial (up to 10 ml) are swallowed, serious adverse reactions are unlikely to occur.

With intensive and prolonged local use, systemic effects may develop.

Analogues of Sofradex, price in pharmacies

If necessary, you can replace Sofradex drops with an analogue in terms of therapeutic effect - these are the following drugs:

Tobrazon,
Aurisan,
DexaTobropt,
Otipax,
Otizol,
Dexon,

When choosing analogues, it is important to understand that the instructions for use of Sofradex, the price and reviews do not apply to drops of similar action. It is important to consult a doctor and not change the drug yourself.

Price in Russian pharmacies: Sofradex 5 ml eye/ear drops – from 293 to 372 rubles, according to 738 pharmacies.

Store at temperatures up to 25 °C out of the reach of children. Shelf life – 2 years, after the first opening of the bottle – 1 month.

Dispensing conditions from pharmacies are by prescription.

What do the reviews say?

Most reviews are positive and talk about the effectiveness of Sofradex drops for infectious and inflammatory diseases. Eye drops cope with the problem of stye in 4-5 days, and ear drops cope with acute and chronic external otitis.

Among the disadvantages, reviews note tingling and itching, increased intraocular pressure.

"Sofradex" is considered one of the effective remedies for otitis media, conjunctivitis, blepharitis and many other diseases. Is it prescribed to children and in what doses is it used in childhood?

Release form

The drug is presented in drops, which are both eye and ear. According to its physical properties, Sofradex is a transparent solution with a peculiar odor. It is almost colorless and is placed in a glass bottle in an amount of 5 ml. The bottle comes with a transparent plastic dropper cap.

Compound

The action of Sofradex is ensured by three ingredients at once:

dexamethasone (this substance is present in drops in the form of sodium metasulfobenzoate at a dosage of 500 mcg/1 ml);
framycetin sulfate (this component is contained in 1 ml of solution in an amount of 5 mg);
gramicidin (the dose of such a substance in 1 ml of the drug is 50 mcg).

Additionally, phenylethanol, lithium chloride and sterile water are added to the medicine. In addition, the solution includes ethyl alcohol, sodium citrate, polysorbate 80 and citric acid.

Operating principle

The effect of Sofradex on the human body is due to its active components.

Framycetin is an aminoglycoside antibiotic, so it has a bactericidal effect on many bacteria, including staphylococcus, Proteus, E. coli and other microorganisms.
Gramicidin also belongs to antibacterial agents, but from the group of cyclic polypeptides. This ingredient has high activity against staphylococcus and other microbes.
Dexamethasone, as a glucocorticoid hormone, it has a pronounced anti-inflammatory effect, that is, it suppresses the inflammatory process. This substance also has an antiallergic effect.

If the drug is used in the eyes, it helps to get rid of lacrimation, burning, pain, and photophobia. When used in the ear, the medication helps relieve itching, redness, stuffiness and other symptoms of inflammation.

Indications

The drug is prescribed for bacterial damage to the anterior part of the eye. Sofradex is dripped for:

blepharitis;
keratitis (if the epithelium is not damaged);
conjunctivitis;
sclerite;
iridocyclitis;
episcleritis;
eczema of the eyelid skin (if it is infected).

This medicine is no less in demand for inflammation of the outer ear, and for otitis media, this medicine is recommended to be dripped into the nose.

Some ENT doctors prescribe Sofradex for the nose and for persistent runny nose or sinusitis to prevent the appearance of otitis media. In addition, drops can also be prescribed for adenoids.

From what age is it used?

The annotation for the drops states that the medication should not be used in infants, and the drug should be prescribed to young patients with caution. Small children should not take Sofradex without medical supervision.

Contraindications

The medication is not used:

if you are intolerant to any of the active or auxiliary components;
for glaucoma;
with fungal infection of the eyes;
with a viral eye infection;
with thinning of the sclera or damage to the cornea;
with herpetic keratitis;
for eye tuberculosis, as well as trachoma;
if the tympanic septum is damaged.

Side effects

Some children, after instilling Sofradex, experience an allergic reaction to its ingredients, for example, burning, dermatitis or itching. If you use the drug in the eyes for a very long time, there may be an increase in intraocular pressure, blurred vision, thinning of the cornea and other negative effects. In addition, due to long-term treatment with Sofradex, a secondary fungal infection may develop.

Instructions for use

For children with eye disease, the medicine is administered into the conjunctival sac, 1 or 2 drops, and the treatment regimen depends on the severity of the infection. If the disease is mild, then drops are used at intervals of 4 hours. If the infection is severe, then Sofradex can be instilled every hour. As soon as the inflammation begins to decrease, the frequency of use of the drops is reduced.

If the medication is prescribed for ear inflammation, a single dosage will be 2-3 drops. The drug is administered 3 or 4 times a day. It can not only be dripped directly into the ear canal, but also applied to a gauze swab that is inserted into the ear.

If Sofradex is prescribed for sinusitis or rhinitis, it is dripped into each nasal passage 2-5 drops three times a day (can be prescribed four times). Sometimes the doctor advises diluting the drops with saline solution and then dripping it into the child’s nose.

When treating adenoids, a special regimen is used, which is selected by the attending physician. To eliminate adenoiditis, the drug can be dripped or inhaled with a diluted product (use a nebulizer, distilled water and proportions 1: 3 or 1: 4).

The duration of use of Sofradex for a particular disease should be determined by a doctor. In this case, the medicine is usually not used for more than one week, so as not to provoke side effects.

Overdose

An excessively high dose of the drug can cause negative systemic effects and also have a negative effect on the kidneys and inner ear. If your child accidentally drinks the contents of the bottle, there will be no serious side effects.

Interaction with other medications

Sofradex should not be used with other antibacterial agents that have ototoxic or nephrotoxic effects (for example, gentamicin), as this will increase the risk of side effects.

Terms of sale

To purchase Sofradex at a pharmacy, you need a prescription from a doctor. The average cost of one bottle of drops is 300 rubles.

Storage

It is recommended to keep the sealed medicine at home at a temperature below +25 degrees, out of the reach of children. The shelf life of Sofradex is 2 years. The opened drug can be stored for no longer than 1 month.

Reviews

According to many mothers and ENT doctors, Sofradex is an affordable and effective remedy for barley, conjunctivitis, otitis externa and many other diseases. It has a rapid anti-inflammatory effect, due to which the condition of the sick child soon improves. However, in some cases, the medication does not help (for example, if treatment is started at the wrong time), which leads to the appearance of negative reviews. There are also sometimes complaints about side effects and a short shelf life.

Analogues

One of the most popular analogues of Sofradex is the drug "Polydexa". It can be used for ear diseases and dripped into the nose, but is available in two different forms. The medication, which is dripped into the nose, additionally contains a vasoconstrictor component, as indicated in its name (“Polydex” with phenylephrine).

The basis of Polidexa is also dexamethasone and two antibacterial drugs. The antibiotics in such drops belong to the same groups as the ingredients of Sofradex, however, instead of framycetin, Polidex contains neomycin, and gramicidin is replaced by polymyxin B. But since they act in a similar way, Polidex can also be used for all those indications when Sofradex is prescribed.

The drug in the form of ear drops is prescribed at any age, and Polidexa with phenylephrine, which is a nasal spray, is approved for children over 2 and a half years old. Both medications are prescription drugs, the average price of drops in the ears is 240 rubles.

Sofradex drops are used in practice not only for the treatment of infectious diseases of the eyes and ears, but also for sinusitis and adenoids in children. The action of this medicine is based on a combination of antibiotics and a hormone. Sofradex allows you to avoid surgical removal of adenoids.

Release form

Sofradex is available in the form of drops and ointments.

Drops– a colorless, tasteless solution with the smell of alcohol. Sold in 5 ml bottles. Each of them has a plug with a dropper.
Ointment produced in tubes of 15 and 20 g.

Compound

Sofradex drops and ointment have a similar composition. The medicine includes:

framycetin sulfate;
gramicidin;

The preparations also contain auxiliary components - citric acid and water, and ethanol in drops.

Operating principle

The mechanism of action of the drops is based on three main components, which complement and enhance each other’s action. Thus, framycetin sulfate has a bactericidal effect, suppressing such common microorganisms as Staphylococcus aureus and Escherichia coli. Gramicidin also fights staphylococcus.

Dexamethasone acts as an anti-inflammatory and antiallergic agent.

Indications

The instructions for use say that Sofradex is drops for the eyes and ears. If you drop them into the eyes, the medicine reduces pain, burning, and lacrimation. And when instilled into the ears, the remedy reduces the symptoms of otitis media, pain, burning, and a feeling of fullness in the ear.

However, Sofradex is also prescribed by doctors for the treatment of nasal congestion, as well as adenoids.

The use of this remedy for adenoids helps to stop the manifestations of rhinitis, relieves swelling of the nasal mucosa, and helps restore nasal breathing.
Sofradex helps with allergic rhinitis, as well as with sinusitis in schoolchildren.

At what age is it prescribed?

Sofradex is not prescribed for the treatment of infants. Exceptions can only be individual indications.

Contraindications

Sofradex is not used to treat children with intolerance to one of the components of the drug. The following diseases are also contraindications:

tuberculosis;
viral or fungal infections;
corneal damage (including ulcers, glaucoma).

Sofradex should not be instilled if there is perforation, that is, if the eardrum is ruptured, which is often a consequence of advanced otitis media.

Side effects

During treatment with Sofrodex, two types of side effects may occur.

First caused by local action of the hormone. Symptoms include increased intraocular pressure and loss of visual acuity.
Second group symptoms are associated with allergic reactions to its components. This is burning, itching, pain at the injection sites. These signs may not appear in the first days of treatment, but later.

Since the instructions for use do not indicate the possibility of administering the drug intranasally (through the nose), the symptoms associated with the treatment of nasal congestion and adenoids are not listed.

However, it can be assumed that children may experience side effects similar to those observed with other antibiotics (regardless of the form of administration):

nausea;
vomit;
decreased appetite;
diarrhea.

Instructions for use

For rhinitis in children, during the first five days of treatment, instill 4 drops into each nostril, and for the next 5 days, 2 drops (if necessary).

The treatment regimen for adenoids is somewhat different. Adenoids are overgrown tissue in the nasal cavity. In fact, it protects the body from infections, but if the child is often sick, it can grow, interfering with normal breathing. Adenoids are treated with medication or removed surgically. The first way is, of course, more preferable.

To treat adenoids, during the first 10 days you need to administer 4 drops into each nasal passage 2 times a day. Then instill 2 drops 2 times a day for another 5 days, and then 2 drops (once a day) for 5 days. The practice of using the drug shows that after 5 days the size of the adenoids decreases, nasal breathing is restored (including during sleep).

The use of Sofradex in the form of drops allows you to avoid surgery to remove the adenoids, which is always associated with stress, anxiety, and pain in children.

For otitis media, children are given drops of:

2-3 drops in each ear 3 or 4 times a day;
and 1-2 drops per eye 3-7 times a day.

It is important to ensure that the medicine does not leak out of your nose or ears. Therefore, before the procedure, they need to be cleaned and the child laid horizontally. After instillation, you need to make sure that the patient lies on his back for several minutes.

The bottle should be tightly closed after each use.

The usual duration of treatment does not exceed 7 days, but if significant improvements are noticeable, then, as prescribed by the doctor, it can be extended for a few more days.

Overdose

An overdose of Sofradex can occur in two cases:

with long-term treatment;
with a single large dose.

If the treatment is delayed (regardless of the method of administration), the child may experience allergic reactions, including increased intraocular pressure, itching and burning at the injection site - the eyes, nose or ear canal.

If a child accidentally swallows no more than 10 ml of medication, then usually overdose symptoms do not appear. However, it is better for parents to take certain measures:

firstly, report the incident to the doctor;
secondly, give the child “Smecta”, “Enterosgel” or activated carbon, as well as any absorbent drug and monitor his condition.

If signs of worsening occur, seek emergency medical attention.

Interaction with other drugs

Since Sofrodex contains two antibiotics, there is no need to combine its use with other similar medications. Particular care should be taken in parallel treatment with agents that have ototoxic and nephrotoxic effects, for example, streptomycin.

Terms of sale and storage

"Sofradex" as a drug containing antibiotics, is sold in pharmacies only with a doctor's prescription. At home, it should be stored at room temperature and in a place protected from direct sunlight.

The shelf life of the drug is 2 years from the date of production. You should not give children expired medicine - this can have unpredictable consequences.

It is important that after opening the bottle, the shelf life of the drug is no more than 1 month.

A drug with antibacterial and anti-inflammatory effects for topical use in ophthalmology and ENT practice

Active ingredients

Framycetin sulfate (framycetin)
- (as sodium metasulfobenzoate) (dexamethasone)
- gramicidin

Release form, composition and packaging

Eye and ear drops in the form of a clear, almost colorless solution, with the odor of phenylethyl alcohol.

Excipients: lithium chloride, sodium citrate, citric acid monohydrate, phenylethanol, ethanol 99.5%, polysorbate 80, water for injection.

5 ml - dark glass bottles (1) complete with a dropper - cardboard packs.

pharmachologic effect

Framycetin sulfate is an antibiotic from the group of aminoglycosides and has a bactericidal effect. It has a wide spectrum of antibacterial action, is active against gram-positive microorganisms, including Staphylococcus aureus, and most clinically significant gram-negative microorganisms (Escherichia coli, dysentery bacillus, Proteus, etc.). Ineffective against steptococci. Does not affect pathogenic fungi, viruses, anaerobic flora. Resistance of microorganisms to framycetin sulfate develops slowly. Gramicidin - has a bactericidal and bacteriostatic effect, expands the spectrum of antimicrobial action of framycetin due to its activity against staphylococci, since it also has an antistaphylococcal effect.

Dexamethasone is a corticosteroid that has a pronounced anti-inflammatory and desensitizing effect. Dexamethasone suppresses inflammatory processes by inhibiting the release of inflammatory mediators, the migration of mast cells and reducing capillary permeability. When instilled into the eyes, it will reduce pain, burning, lacrimation, and photophobia. When instilled into the ears, it reduces the symptoms of the outer ear (redness of the skin, pain, itching, burning in the external auditory canal, feeling of ear congestion).

Pharmacokinetics

When applied topically, systemic absorption is low.

Framycetin sulfate can be absorbed through inflamed skin or open wounds. Once it enters the systemic circulation, it is quickly excreted unchanged by the kidneys. T1/2 of framycetin sulfate is 2-3 hours.

When taken orally, dexamethasone is rapidly absorbed from the gastrointestinal tract. T 1/2 is 190 min.

Indications

Contraindications

increased individual sensitivity to any of the components of the drug;
viral or fungal infections, tuberculosis, purulent inflammation of the eyes, trachoma;
violation of the integrity of the corneal epithelium and thinning of the sclera;
herpetic keratitis (tree-like corneal ulcer) (possible increase in the size of the ulcer and significant deterioration of vision);
glaucoma;
perforation of the eardrum (penetration of the drug into the middle ear can lead to the development of ototoxicity);
pregnancy and lactation;
infants.

Carefully: young children (especially when prescribing the drug in large doses and for a long time - the risk of developing systemic effects and suppressing adrenal function).

Dosage

At eye diseases: at mild course of the infectious process instill 1-2 drops of the drug into the conjunctival sac of the eye every 4 hours. In case of development severe infectious process the drug is instilled every hour. As inflammation decreases, the frequency of drug instillations decreases.

At : instill 2-3 drops 3-4 times a day; a gauze swab moistened with a solution can be placed in the external auditory canal.

The duration of use of the drug should not exceed 7 days, except in cases of obvious positive dynamics of the disease (GCS can mask hidden infections, and long-term use of the antimicrobial components of the drug contributes to the development of resistant flora).

Side effects

Allergic reactions usually of a delayed type, manifested by irritation, burning, pain, itching, dermatitis.

At long-term use of topical corticosteroids possible: increased intraocular pressure with the development of the symptom complex of glaucoma (damage to the optic nerve, decreased visual acuity and the appearance of visual field defects), therefore, when using drugs containing glucocorticosteroids for more than 7 days, intraocular pressure should be measured regularly; development of posterior supcapsular cataract (especially with frequent instillation); thinning of the cornea or sclera, which can lead to perforation; addition of a secondary (fungal) infection.

Overdose

Prolonged and intensive topical use may lead to systemic effects. Treatment is symptomatic.

When swallowing the contents of one vial (up to 10 ml of solution), the development of serious side effects is unlikely.

Drug interactions

Framycetin sulfate should not be used together with other antibiotics that have ototoxic and nephrotoxic effects (monomycin, kanamycin, gentamicin).

special instructions

With long-term use of the drug, as with long-term use of other antimicrobial agents, the development of superinfections caused by drug-resistant microorganisms, including fungi, is possible.

Long-term instillation of the drug into the eyes can lead to thinning of the cornea with the development of its perforation, as well as to an increase in intraocular pressure. Treatment with drugs containing corticosteroids should not be repeated or prolonged without regular monitoring of intraocular pressure and eye examination for the development of cataracts or secondary infections.

Local corticosteroids should never be used in patients with ocular hyperemia of unknown cause, because inappropriate use of the drug can lead to significant visual impairment.

Framycetin sulfate, which is part of the drug, is an antibiotic from the group of aminoglycosides, which tend to develop nephro- and ototoxic effects when used systemically or topically on an open wound or damaged skin. These effects are dose dependent and are increased by both renal or . Although the development of these effects was not observed when the drug was instilled into the eyes, the possibility of their occurrence should be taken into account in the case of topical use of high doses of the drug in children.

The duration of use of the drug should not exceed 7 days, except in cases of obvious positive dynamics of the disease, because long-term use of GCS, which is part of it, can mask hidden infections, and long-term use of antimicrobial components can contribute to the development of resistant flora.

Influence on the ability to drive vehicles and operate machinery.

Patients who temporarily lose clarity of vision after instilling the drug into the eye are not recommended to drive a car or work with complex machinery, machines or any other complex equipment that requires clear vision immediately after instilling the drug.

Storage conditions and periods

Store at a temperature not exceeding 25°C. Keep out of the reach of children. Shelf life: 2 years. Do not use after the expiration date indicated on the package.

The drug Sofradex is drops that have a combined effect. The drug belongs to antibacterial drugs and glucocorticosteroids. Ear drops are widely used in the treatment of diseases of the ENT organs.

General information

Ear drops have three main components:

Framycetin sulfate. The substance has a strong antibacterial effect on many pathogenic microorganisms. An important feature of the substance is that resistance to it in microorganisms develops very slowly, which means its use will bring good results;
gramicidin. It is an antibiotic that has a bactericidal and bacteriostatic effect, thereby enhancing the effect of framycetin sulfate;
dexamethasone. The substance belongs to glucocorticosteroid drugs. Dexamethasone has anti-inflammatory and antiallergic effects.

In addition to the main components, ear drops called Sofradex contain excipients:

citric acid;
distilled water;
methylated alcohol, etc.

Sofradex drops are a clear, almost colorless solution. The solution has the odor of phenylethyl alcohol.

Considering the components that make up the drug, we can note what effect the medicine has on the body:

bactericidal;
bacteriostatic;
antimicrobial;
antistaphylococcal;
antiallergic.

The drug is available in plastic bottles

Indications for use

The product is used in the following cases:

blepharitis;
conjunctivitis;
keratitis;
iridocyclitis;
bacterial infection of the ears;
scleritis;
otitis externa. This applies to both acute and chronic forms.

Contraindications

Any drug has a number of limitations, and these drops are no exception. Most people simply do not pay attention to the existing contraindications. And in vain, because such carelessness can lead to serious complications.

Drops should not be used in the following cases:

for tuberculosis;
fungal, purulent or viral infections;
rupture of the eardrum;
if eye drops are used, then for glaucoma or keratitis;
children under three years of age;
hypersensitivity to any component of the product.

The drug should not be used during pregnancy and breastfeeding

Application

Instructions for use of the product include knowledge of the correct dosages and quantities of the drug administered.

A few drops of the medicine should be dripped into the ears up to four times. You can also soak a gauze pad in the solution and leave it in your ears overnight.

The duration of use of the medicine should not be more than a week, otherwise microorganisms will become resistant to the substances contained in the drug.

It is best not to combine ear drops with other antibiotics!

The price of the medicine will please buyers. It may vary depending on the pharmacy chain and city. On average, it fluctuates around 200 rubles.

Analogues of Sofradex are Betagenot, as well as Garazon. These analogues contain similar components and have almost the same effect.

Sofradex in the nose can be used for a child with adenoids, as well as with sinusitis. Drops are also used for prolonged runny nose. This is done to prevent infection from entering the ear.

Also, for allergic rhinitis, the remedy is a real salvation, because with this disease, vasoconstrictor drops cannot be used. The drug has a cleansing effect on the nasal mucosa and also restores breathing.

For adenoids, the drug is administered three times a day. As a result, breathing will become easier and the adenoids will decrease in size.

The drug is used with caution in children of the first year of life. In this case, you should consult a specialist