Vitamins Lekhim Alpha-tocopherol acetate (vitamin E) - “An irreplaceable and cheap liquid vitamin E. A product that will not leave you indifferent! Read our review about how to rejuvenate your skin, give it elasticity and a radiant look!”

Vitamin E is a very strong antioxidant. It prevents many diseases, disorders in the functioning of individual organs, and prevents the formation of free radicals.

The active ingredient of vitamin E is tocopherol, which removes toxins and chemicals from the body and prevents the formation of carcinogens. Thanks to it, the cells are saturated with oxygen. Tocopherol helps improve cell nutrition and protect red blood cells from toxic effects. The walls of blood vessels are strengthened, blood circulation improves. Vitamin E prevents the formation of blood clots.

Use of vitamin E

This vitamin substance is used in many areas of medicine and cosmetology. It is prescribed both independently and in combination with other vitamins and medications.

Daily intake of Vit.E capsules prevents the occurrence of many diseases. Lack of tocopherol leads to the destruction of red blood cells, which causes anemia. Muscle tissue weakens, diseases of the nervous system occur, and the reproductive functions of the body are destroyed.

There are natural and synthetic forms of vitamin E. Natural is found in food. And synthetic forms are made for medicinal use: for injection, for oral administration in the form of lozenges and capsules. These drugs are manufactured to treat specific diseases and in accordance with the physiological characteristics of those for whom they are intended.

Vitamin E in gelatin capsules, once in the stomach, dissolves well and is almost completely absorbed under the influence of bile acid. In lymph, it is distributed throughout the body without changing its qualities. Tocopherol inhibits the oxidation of vitamin A, promotes its accumulation in the liver, and strengthens muscle activity thanks to glycogen.

After suffering severe illnesses (fever, hyperthermia), it is extremely necessary to take Vit.E capsules. As an adjuvant, tocopherol is taken for heart disease (ischemia, atherosclerosis), reducing the permeability and fragility of capillaries. Tocopherol is used in the treatment of diseases of joints and ligaments, and muscular dystrophy. Vitamin E is also prescribed for many eye diseases: macular degeneration of the retina, sclerosis of the vessels of the fundus.

Positive results are obtained from the use of vitamin E in the treatment of skin diseases - psoriasis, seborrhea, various dermatoses, as well as in the treatment of burns and injuries.

It has a positive effect on the reproductive function of the male and female body. As an addition to the main treatment, it is used for menopausal syndrome, menstrual irregularities, increased sweating, for the treatment of prostatitis, and impotence. During pregnancy, the drug is prescribed in the first trimester.

Tocopherol is not recommended to be taken simultaneously with multivitamins, since you can exceed the daily requirement of vitamin E (15 mg). It is unacceptable to take it with iron supplements and vitamin K, as this affects blood clotting.

Tocopherol enhances the effect of anti-inflammatory and hormonal drugs, and in some cases can provoke heart and epileptic attacks. In case of overdose, vitamin E can cause allergies and even poisoning. Therefore, it is very important to follow the instructions for use. If diarrhea, pain in the epigastrium, kidneys and liver occurs, the dosage of the drug should be reconsidered.

Vitamin E is widely used in cosmetology. This is because it has antioxidant and restorative properties. It is included in products intended for skin and hair care. Creams made using this substance have nourishing, moisturizing, and regenerating properties. Cosmetics using tocopherol help saturate skin cells with oxygen and give it youth.

Traditional medicine based on an oil solution of vitamin E offers masks for hair, hands and nails.

It should be recalled that, in addition to medications, vitamin E is found in many foods that are consumed every day.

Products containing vitamin E

  • It is found in rye bread, loaves, crackers, hearth table bread and other bakery products.
  • There is quite a lot of vitamin E in cereals and porridges made from them: rice, peas, wheat, buckwheat, oatmeal, pearl barley.
  • There is not much of it in animal products (beef, veal, chicken).
  • And chicken eggs contain 2 mg of vitamin per 100 g of product (this is quite enough).
  • It is present in small quantities in fish. Most of it is found in Atlantic herring (1.2 mg).
  • Fruits and vegetables also contain vitamin E in small quantities, but dairy products contain virtually none.
  • Most tocopherol is found in vegetable oils - refined sunflower, cottonseed, corn, coconut, nut, olive and others.
  • It is necessary to include in your diet as many vegetable salads as possible and season them with vegetable oil and at the same time provide yourself with vitamin E without the risk of overdose.
Oral oil solution 5%: fl. 20 ml

Oily oral solution 5%

Excipients:

Oral oil solution 10%: fl. 20 ml
Reg. No: 6334/03/08 dated 06/28/2008 - Canceled

Oral oil solution 10% from light yellow to dark yellow, transparent, without rancid odor; A greenish tint is allowed.

Excipients: Refined sunflower oil or refined deodorized sunflower oil, brand "P", frozen.

20 ml - bottles (1) - packaging.

Oral oil solution 30%: fl. 20 ml
Reg. No: 6334/03/08 dated 06/28/2008 - Canceled

Oral oil solution 30% from light yellow to dark yellow, transparent, without rancid odor; A greenish tint is allowed.

Excipients: Refined sunflower oil or refined deodorized sunflower oil, brand "P", frozen.

20 ml - bottles (1) - packaging.

Description of the drug ALPHA-TOCOPHEROL ACETATE (VITAMIN E) oil solution for oral administration created in 2010 on the basis of instructions posted on the official website of the Ministry of Health of the Republic of Belarus. Update date: 04/20/2011


pharmachologic effect

Vitamin E is an antioxidant that protects various endogenous substances in the body from oxidation. Inhibits lipid peroxidation, which is activated in many diseases. Takes part in the processes of tissue respiration, biosynthesis of heme and proteins, metabolism of fats and carbohydrates, cell proliferation, etc. With vitamin E deficiency, degenerative changes develop in the muscles, capillary permeability and fragility increase, the epithelium of the seminiferous tubules and testicles degenerates, and degenerative processes are observed in the nervous tissue and hepatocytes. Vitamin E deficiency can cause hemolytic jaundice of newborns, malabsorption syndrome, and steatorrhea.

Pharmacokinetics

The drug is absorbed in the intestine in the presence of fat and bile acids; the mechanism of absorption is passive diffusion. Transported as part of blood b-lipoproteins, the maximum concentration is reached by the 4th hour after administration. It is excreted in feces and conjugants and tocopheronic acid are excreted in urine.

Indications for use

Vitamin E hypovitaminosis, treatment of muscular dystrophies of various types and origins, dermatomyositis, Dupuytren's contracture, amyotrophic lateral sclerosis, psoriasis, to increase the effectiveness of anticonvulsants for epilepsy.

Dosage regimen

Alpha-Tocopherol acetate (Vitamin E) is prescribed orally.

The drug is used internally in the form of 5%, 10% and 30% oil solutions. 1 ml of solution contains 0.05 g, 0.1 g and 0.3 g of alpha-Tocopherol acetate, respectively (1 ml of solution contains 30 drops from an eye pipette). The daily requirement is 0.01 g per day.

To prevent hypovitaminosis E in adults, take up to 0.01 g (6 drops of a 5% solution) per day. For the treatment of hypovitaminosis E, take from 0.01 g to 0.04 g (3-12 drops of 10% solution) per day.

For muscular dystrophies, amyotrophic lateral sclerosis, and other diseases of the neuromuscular system, the daily dose is 0.05-0.1 g (15-30 drops of a 10% solution). Take for 30-60 days with repeated courses after 2-3 months. If spermatogenesis and potency are impaired in men, the daily dose is 0.1-0.3 g (1030 drops of a 30% solution). In combination with hormonal therapy, it is prescribed for 30 days.

If there is a threat of miscarriage, alpha-Tocopherol acetate (Vitamin E) is taken at a daily dose of 0.1-0.15 g (10-15 drops of a 30% solution) for 7-14 days. In case of abortion and deterioration of intrauterine development of the fetus, 0.1-0.15 g (10-15 drops of a 30% solution) per day is prescribed daily or every other day for the first 2-3 months of pregnancy. For atherosclerosis, myocardial dystrophy, peripheral vascular diseases, 0.1 g (30 drops of a 10% solution or 10 drops of a 30% solution) of the drug is administered together with vitamin A per day. The course of treatment is 20-40 days with possible repetition of treatment after 3-6 months.

For complex therapy of cardiovascular diseases, eye and other diseases, alpha-Tocopherol acetate (Vitamin E) is prescribed in a dose of 0.05-0.1 g (15-30 drops of 10% solution) 1-2 times a day. The course of treatment is 1-3 weeks.

For dermatological diseases, the daily dose of the drug is 0.05-0.1 g (15-30 drops of a 10% solution). The course of treatment is 20-40 days.

For malnutrition and decreased capillary resistance in infants, use a daily dose of 0.005-0.01 g (3-6 drops of a 5% solution).

For prophylactic purposes, the drug is used at 0.01 g (6 drops of a 5% solution) 1 time per day for 1-3 weeks, for children less than 0.01 g per day.

It is preferable to take the drug during meals.

Side effects

In isolated cases, allergic reactions (itching, skin flushing and rash) may occur. With long-term treatment, in rare cases, nausea, constipation, diarrhea, headache, increased fatigue, weakness, dysfunction of the gonads, thrombophlebitis, hypercholesterolemia are possible.

When using significant doses, minor temporary stomach upset, epigastric pain, headache, dizziness and blurred vision are possible. Taking large doses can aggravate bleeding disorders caused by a lack of vitamin K in the body and dysfunction of the thyroid gland. If the side effect is severe, the drug is discontinued.

Contraindications for use

Hypersensitivity to the drug, severe cardiosclerosis, myocardial infarction, bleeding disorders, hypoprothrombinemia. Take with extreme caution if there is an increased risk of thromboembolism.

  • Tocopherol is a vital substance for the human body, which is responsible for many important functions. For example, it is involved in maintaining cell youth, maintains overall tone, and has an antioxidant effect, neutralizing free radicals. Deficiency leads to many negative changes, such as a drop in immunity, interruptions in the functioning of the reproductive organs in both men and women. In males, sexual impotence may occur, in females - lack of ovulation, cessation of menstruation and infertility. Vitamin E in oil is one of the forms of release of a useful element, the intake of which according to the instructions for use will help compensate for the deficiency of the substance and prevent the development of undesirable consequences. An oil solution containing a biologically active substance is dispensed from a pharmacy without a doctor's prescription. But, despite this, it is advisable to consult a specialist before taking the medicine. Only he can determine the correct dosage and duration of treatment.

    Pharmaceutical companies available with synthetic , ampoules, in the form of an oil solution, intended for oral administration. Vegetables are added as auxiliary components oil , most often refined sunflower, non-deodorized or deodorized. Myself vitamin E belongs to the group. It has no odor, the color is light yellow with an admixture of green.

    Once in the human body, the substance has a positive effect on the functioning of the muscular and nervous systems, and also triggers some metabolic processes.

    Pharmacological properties

    According to the instructions for use, oily vitamin E is absorbed into the bloodstream at the level of the duodenum. Absorption occurs in the presence of bile acids, salts and fats, as well as pancreatic enzymes - without their participation, complete absorption of tocopherol is impossible. On average, about 50-70% of the ingested volume is absorbed, which depends on the individual characteristics of the state of the human body.

    After entering the bloodstream, the vitamin is captured by lipoproteins contained in the blood plasma and, along with them, is distributed throughout the body. In the event that there are disturbances in protein metabolism, the distribution of tocopherol does not occur. The maximum concentration of the element is achieved 4 hours after taking the oil solution. During pregnancy, at least 20% of the element passes into the bloodstream of the fetus, and during breastfeeding, some leaves the mother’s body along with breast milk.

    The processing of the biologically active substance occurs in the liver to the active components, after which the remains are excreted from the body in the urine through the kidneys and through the intestines along with bile. The active components are absorbed back and circulate further throughout the body, performing their functions. Complete removal of tocopherol from the human body takes a long time; in newborns this process is even longer.

    Effect of vitamin E on the body

    Once ingested, the oil solution has various effects:

    • Increases the elasticity of the vascular wall.
    • Prevents the development of dystrophic processes in muscle tissue (including the heart muscle).
    • Prevents the occurrence of oxidative reactions ahead of time.
    • Supports egg maturation and release, increasing the likelihood of conception.
    • important in that it participates in the process of seminal fluid synthesis, stimulating the growth and development of sperm.
    • Increases libido in both men and women.
    • Participates in the synthesis of hemoglobin and red blood cells, promoting plasma renewal.

    In what cases are vitamin preparations prescribed?

    According to the instructions, an oil solution of tocopherol is prescribed for vitamin deficiency or in case of increased need for it in the following cases:

    • Prematurity.
    • Diseases of the peripheral nervous system.
    • Myopathies, including necrotizing.
    • Obstructive jaundice.
    • Cirrhosis of the liver.
    • Pregnancy planning and the first trimester of gestation.
    • Malabsorption syndrome.
    • Celiac disease.
    • Atresia of the biliary tract.
    • Chronic stagnation of bile.
    • Crohn's disease.
    • Parenteral nutrition.
    • Treatment of drug addiction and nicotine addiction.
    • Breastfeeding period.
    • Prevention of hemolytic anemia and newborns .

    Admission restrictions

    Vitamin E in oil and any other dosage forms is not recommended for the following conditions:

    • Increased sensitivity of the body to vitamin E and other components included in the product.
    • A history of stroke and myocardial infarction.
    • Pathologies of the blood coagulation system.
    • High risk of thromboembolism.
    • Sclerosis of the coronary vessels.

    Mode of application

    Before you start taking the oil solution, it is important to consult a specialist and carefully read the instructions.

    Oil solution of tocopherol is available in different concentrations of the active substance - 50, 100 and 300 mg/ml. 1 drop of the drug in the first case contains 1 mg of vitamin E, in the second - 2 mg, in the third - 6 mg.

    The dosage of vitamin E in oil varies depending on the purpose of taking the synthetic drug:

    • To prevent tocopherol deficiency use a 5% solution at a dosage of 10 mg per day.
    • Treatment of identified deficiency - 10-50 mg per day.
    • Treatment of pathologies of the central nervous system and muscle tissue - 50-100 mg per day. The average course of treatment is 1.5 months.
    • Therapy for male infertility - 150-300 mg in combination with hormonal drugs.
    • Threat of miscarriage or premature birth - 100-150 mg.
    • Increased risks of developing fetal abnormalities - 100-150 mg.
    • Treatment of skin pathologies - 70-100 mg.
    • Vascular pathologies - 100 mg in combination with retinol.
    • Underweight in premature babies - 5-10 mg per day.

    The maximum daily dose of vitamin E is 300 mg per day. If it is exceeded, symptoms may develop - nausea, vomiting, general weakness, blurred vision, asthenia, attacks of dizziness.

    With long-term use of high doses, serious disorders can occur - bleeding, loss of libido, impaired potency, thrombophlebitis, changes in the level of thyroid hormones.

    External use of vitamin E

    An oil solution with tocopherol is used and it actively affects the skin, nails and hair, renewing their cells and maintaining a healthy and youthful appearance.

    • Prevents the appearance of age-related changes.
    • Helps get rid of freckles and age spots.
    • Soothes and heals wounds.
    • Protects against free radicals.
    • Maintains water balance and softens the skin.

    In the fight against acne, tocopherol can also provide support - by removing toxins from the body, it helps the sebaceous glands of the skin to become free from blockage. In addition, the vitamin reduces inflammation and increases the body's ability to fight infection.

    The oil solution for external use can be used in various ways: simply applied to problem areas, or added a few drops to creams and face masks.

    The benefits are undeniable - when it comes into contact with the scalp, it nourishes it, stimulates blood flow, thereby accelerating hair growth, and prevents fragility and excessive hair loss. In addition, the vitamin promotes cell regeneration, heals wounds and regulates sebum production. The oil solution can be added a few drops to a factory-made or home-made shampoo or mask.

    For nails, tocopherol is used in the form of baths or masks. It helps prevent brittleness and peeling, improves the appearance of the nail and helps restore the plate after certain diseases. The easiest way to use the oil is to simply rub a drop onto the surface of the nail and surrounding skin.

    Vitamin E oil solution is easy to use and easy to dose. When taken correctly, the effect occurs quickly enough, and side effects rarely develop. An important condition is the correct dosage and duration of treatment.

    oily oral solution 5%, 10% and 30%

    Registration number: P N001153/01
    Tradename:α-Tocopherol acetate.
    International nonproprietary name: alpha tocopherol acetate
    Dosage form: oral solution [oil]
    Description
    Transparent oily liquid from light yellow to dark yellow color without rancid odor. A greenish tint is allowed.
    Compound
    Active substance: Vitamin E (α-Tocopherol acetate) – 50 g, 100 g and 300 g;
    Excipients– sunflower oil (refined deodorized sunflower oil) – up to 1 liter.
    Pharmacotherapeutic group: vitamin
    ATH CODE:[A11NA03]

    Pharmacological properties

    Vitamin E is a natural antioxidant. Protects cell membranes of body tissues from oxidative changes; stimulates the synthesis of heme and heme-containing enzymes - hemoglobin, myoglobin, cytochromes, catalase, peroxidase. Inhibits the oxidation of unsaturated fatty acids and selenium. Inhibits cholesterol synthesis. Prevents hemolysis of red blood cells, increased permeability and fragility of capillaries, dysfunction of seminiferous tubules and testicles, placenta, normalizes reproductive function; prevents the development of atherosclerosis, degenerative-dystrophic changes in the heart muscle and skeletal muscles.

    Indications for use

    Hypovitaminosis E; complex therapy of conditions accompanied by an increased need for vitamin E:
    for muscular dystrophies, dermatomycosis, amyotrophic lateral sclerosis, asthenic and neurasthenic syndromes, fatigue, paresis, myasthenia gravis, myopathies, menstrual irregularities, threat of miscarriage, menopause, dysfunction of the gonads in men and women;
    for dermatoses, psoriasis;
    with atrophy of the mucous membrane of the respiratory tract, periodontal disease;
    for rheumatic diseases: fibrositis, tendinopathy, diseases of the joints and spine;
    for endocrine diseases: thyrotoxicosis, diabetes mellitus, especially ketoacidosis, diabetic polyneuropathy;
    with malabsorption syndrome, chronic liver diseases;
    with myocardial dystrophy, spasms of peripheral vessels.
    In a state of convalescence after illnesses that occurred with a febrile syndrome.

    Contraindications

    Increased individual sensitivity to the drug.
    With caution: hypoprothrombinemia (due to vitamin K deficiency - may increase with a dose of vitamin E more than 400 IU), severe atherosclerosis of the coronary arteries, myocardial infarction, increased risk of thromboembolism.

    Directions for use and doses

    For oral administration, the drug is prescribed in the following doses:
    For diseases of the neuromuscular system (myodystrophy, amyotrophic lateral sclerosis, etc.) 50-100 mg per day (50-100 drops of a 5% solution, 25-30 drops of a 10% solution or 7-15 drops of a 30% solution) for 1- 2 months. Repeated courses after 2-3 months.
    For men with disorders of spermatogenesis and potency, 100-300 mg per day (100-300 drops of a 5% solution, 50-150 drops of a 10% solution or 15-46 drops of a 30% solution) in combination with hormonal therapy for a month.
    For threatened abortion, 100-150 mg per day (100-150 drops of a 5% solution, 50-75 drops of a 10% solution or 15-23 drops of a 30% solution).
    In case of habitual abortion and deterioration of intrauterine development of the fetus, 100-150 mg per day (100-150 drops of a 5% solution, 50-75 drops of a 10% solution or 15-23 drops of a 30% solution) in the first 2-3 months of pregnancy daily or every other day.
    For peripheral vascular diseases, myocardial dystrophy, atherosclerosis, 100 mg per day (100 drops of a 5% solution, 50 drops of a 10% solution or 15 drops of a 30% solution) in combination with vitamin A. Course duration 20-40 days, after 3-6 months the course of treatment can be repeated.
    For skin diseases, from 15 to 100 mg per day (15-100 drops of a 5% solution, 7-50 drops of a 10% solution or 2-5 drops of a 30% solution) for 20-40 days.
    1 drop from an eye pipette contains: α - Tocopherol acetate in a 5% solution – 1 mg, in a 10% solution – 2 mg; in a 30% solution – 6.5 mg.

    Side effect

    Allergic reactions. The use of large doses of the drug can cause dyspeptic disorders, decreased performance, weakness, thrombophlebitis, pulmonary embolism, thrombosis, increased creatine kinase activity, creatinuria, hypercholesterolemia, white hair growth in areas of alopecia with epidermolysis vesicularis.

    Overdose

    Symptoms: when taken for a long period in doses of 400-800 IU / day (1 mg = 1.21 IU) - blurred vision, dizziness, headache, nausea, unusual fatigue, diarrhea, gastralgia, asthenia, when taking more than 800 U/day for a long period - increased risk of bleeding in patients with hypovitaminosis K, impaired metabolism of thyroid hormones, sexual function disorders, thrombophlebitis, thromboembolism, necrotizing colitis, sepsis, hepatomegaly, hyperbilirubinemia, renal failure, hemorrhage in the retina of the eye, hemorrhagic stroke, ascites.
    Treatment: symptomatic, drug withdrawal, administration of glucocorticosteroid drugs.

    Interaction with other drugs

    Enhances the effect of glucocorticosteroid drugs, non-steroidal anti-inflammatory drugs, antioxidants.
    Increases the effectiveness and reduces the toxicity of vitamins A, D, cardiac glycosides.
    Prescribing vitamin E in high doses can cause vitamin A deficiency in the body.
    Increases the effectiveness of antiepileptic drugs in patients with epilepsy (who have increased levels of lipid peroxidation products in the blood).
    Simultaneous use of vitamin E in a dose of more than 400 IU/day with anticoagulants (coumarin and indanedione derivatives) increases the risk of developing hypoprothrombinemia and bleeding.
    Cholestyramine, colestipol, and mineral oils reduce absorption.
    High doses of iron increase oxidative processes in the body, which increases the need for vitamin E.

    special instructions

    Oil solutions of vitamins A and E are used to treat and prevent many diseases. When taken orally, the drugs are quickly absorbed into the blood and spread through the bloodstream, producing a prolonged effect. When taken together, the beneficial effect on the body is enhanced.

    Effect of vitamin A oil

    Retinol is an analogue of a natural substance. The body's reserves are replenished with foods - carrots, pumpkin, spinach. The oil solution is called Retinol acetate.

    Vitamin A isolates free radicals in the epithelium, improves the conductivity of nerve impulses, and stimulates the regeneration of the skin and mucous membranes. The substance is involved in metabolic processes and the production of lipids, proteins and polysaccharides, and prevents the development of diabetes.

    One of the main properties is stimulation of the synthesis of rhodopsin (the visual pigment responsible for twilight vision).

    Effect of vitamin E oil

    The substance is produced in the liver and enters the body along with foods - vegetable oils, nuts, sea buckthorn. The oily solution is sold under the name Alpha-tocopherol acetate.

    Taking it increases the elasticity of the walls of blood vessels, reduces the likelihood of developing dystrophic processes in the heart muscle, increases the synthesis of hemoglobin and improves the quality of plasma.

    An important role of the drug is to stabilize the functions of the reproductive system. In men, it improves the quality of seminal fluid, and in women, it increases the possibility of pregnancy by accelerating the maturation of healthy eggs.

    Indications for the simultaneous use of oil solutions of vitamins a and e

    • night blindness and optic nerve atrophy;
    • psoriasis and retinitis pigmentosa;
    • disturbance of peripheral blood supply;
    • endarteritis and obliterating endocarditis, systemic lupus erythematosus;
    • atherosclerosis.

    The combined effect of oil solutions of vitamins a and e

    Simultaneous use enhances the beneficial effect on the body. If retinol treatment is not supported by the administration of tocopherol, the substance will not be fully absorbed, but will be partially oxidized in the blood plasma and small intestine. Vitamin A stimulates the antioxidant effect of vitamin E.

    Since retinol is synthesized by the body, an overdose can occur when taken from the outside. Tocopherol helps prevent the accumulation of vitamin A by limiting liver stores.

    How to use

    The vitamin complex should not be used without a doctor's prescription. Alpha tocopherol is prescribed with caution to children under 12 years of age. The average daily intake for adults is 100 mg. The recommended duration of treatment is up to 4 weeks.

    When determining the dosage of Retinol, the patient's age and physiological status are taken into account.

    Correction of the therapeutic regimen is allowed for vitamin deficiency, dermatological diseases and decreased vision.

    For ease of use, it is better to purchase vitamins for oral administration in capsules. Alpha tocopherol is taken up to 3 times a day after meals, Retinol - 1 time, in the morning.

    It is advisable to add 20-30 drops of lemon juice to the water that is intended for washing down the medicine. The vitamin C it contains increases the rate of absorption of the drug complex into the bloodstream and enhances the antioxidant function.

    Solutions of vitamins A and E in oil can be purchased in ampoules. In this case, the dosage and frequency of use are prescribed individually, based on the clinical picture.

    Women add Tocopherol and Retinol to face and hair masks. In this case, it is recommended to purchase ampoules or an oil solution.

    Contraindications for oil solutions of vitamins a and e

    Complex use is contraindicated in case of individual intolerance to each substance or the development of an allergic reaction when used together. Absolute contraindications for treatment:

    • renal and liver failure;
    • thyrotoxicosis;
    • dysfunction of the circulatory system;
    • chronic glomerulonephritis.

    Relative restrictions on prescription are atherosclerosis of the coronary arteries, myocardial infarction and varicose veins. It is recommended to avoid complex treatment with Retinol and Alpha-tocopherol in the first trimester of pregnancy. In the second and third semester, as well as during lactation, vitamins should be prescribed by a doctor.

    Side effects

    In most cases, negative reactions of the body appeared due to an overdose or violation of the frequency of administration. Signs of intolerance: nausea, dizziness, diarrhea, frequent headaches, photophobia, exacerbation of pancreatitis and cholelithiasis. Impaired sweating, peeling of the skin, and alopecia (hair loss) were noted. In rare cases, joint pain and enlarged spleen have occurred.

    No side effects were observed when applied to the skin.

    Doctors' opinion

    Oleg Vladimirovich, therapist, Tula: “Patients do not consider vitamins A and E as medicines and drink without restrictions, and then complain of diarrhea. Combined use - only according to indications, in compliance with the dosage."

    Olga Rifovna, gynecologist, Kazan: “I consider it effective to prescribe for women with irregular ovulation when planning pregnancy.”

    Ilyas Aminovich, dermatologist, Ufa: “I prescribe it for alopecia and excessive dry skin. I recommend purchasing them in capsules and bottles and adding them to skin care products.”

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