Otitis

Drops "Zyrtec" for children: instructions for use. Zyrtec - official* instructions for use of Zyrtec during pregnancy and lactation

Each 10 mg tablet contains the active substance cetirizine dihydrochloride and auxiliary ingredients:

37 mg microcellulose;
66.4 mg lactose monohydrate;
0.6 mg colloidal silicon dioxide;
1.25 mg magnesium stearate.

The film coating consists of 1.078 mg titanium dioxide , 2.156 mg hypromellose and 3.45 mg .

1 ml of drops contains the active ingredient in an amount of 10 mg and excipients:

250 mg glycerol;
350 mg propylene glycol;
10 mg sodium saccharinate;
1.35 mg methylparabenzene;
0.15 mg propylparabesol;
10 mg;
0.53 mg acetic acid;
up to 1 ml of purified water.

Release form

The drug is available in two pharmacological forms:

Film-coated tablets. These are white, oblong tablets with convex surfaces, with a score on one side and an engraved letter “Y” on both sides of the score. 7 or 10 tablets are placed in a blister; 1 blister (7 or 10 tablets each) or 2 blisters (10 tablets each) are placed in a cardboard box.
Zyrtec drops. Externally it is a transparent liquid, without color. Characteristic odor of acetic acid. The liquid is poured into 10 or 20 ml bottles of dark glass, tightly sealed. In addition to the bottle, a dropper cap is placed in the cardboard box.

Pharmacological action

The drug has antihistamine action, so it is taken in order to get rid of .

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Cetirizine, the active ingredient in Zyrtec, is a competitive histamine antagonist. Its effect is due to its ability to block H1 histamine receptors.

Clinical manifestations of action cetirizine :

removed ;
the amount of exudate decreases;
the rate of migration of cells, which are characterized by participation in allergic reactions (eosinophils, neutrophils and basophils), decreases;
the membranes of mast cells are stabilized;
the permeability of small vessels decreases;
spasms of smooth muscles are relieved;
prevented fabrics ;
the skin reaction to some allergens is eliminated (with the introduction of specific antigens or histamine , skin cooling);
in mild stages the severity of histamine-induced bronchoconstriction decreases.

Pharmacokinetics

After the drug is taken orally, it is quickly absorbed from the digestive tract into the blood and is approximately 93% bound to plasma proteins. When consumed simultaneously with food, the absorption rate becomes lower, but the volume of absorbed substance does not change.

The effect appears 20-60 minutes after a single dose and lasts more than a day. Maximum plasma concentration is achieved 1-1.5 hours after administration.

Occurs through O-dealkylation. The resulting product has no pharmacological activity.

The half-life from the body depends on age:

in adults it lasts 10 hours;
for children 6-12 years old – 6 hours;
at the age of 2-6 years – 5 hours;
in children from six months to 2 years – 3.1 hours.

2/3 of the dose that was taken is excreted unchanged through the kidneys. The liver also plays a significant role in the elimination of the drug. Therefore, in chronic liver diseases, the half-life increases by one and a half times, and in cases of moderate severity - by 3 times.

Indications for use

The medicine can be prescribed for the following conditions:

seasonal or year-round with, nasal congestion and ;
with lacrimation and redness of the conjunctiva;
skin allergic reactions in the form or .

Contraindications

Contraindications for the use of Zyrtec:

excessive sensitivity to any ingredient of the drug, individual intolerance;
heavy ;
periods And ;
children under six months.

The drug is prescribed with caution in the following conditions:

chronic renal failure moderate;
advanced age;
, increased convulsive readiness;
the presence of factors predisposing to .

Additional contraindications for Zyrtec tablets:

intolerance galactose ;
malabsorption syndrome, in particular glucose-galactose;
age under 6 years.

Side effects

Side effects of Zyrtec can be divided into those that occur often (at least 1 in 10 people taking the medicine), common (1 in 10-100), uncommon (1 in 100-1000), rare (1 in 1000- 10,000), very rare (less than one in 10,000).

The following side effects are often observed:

fatigue;
nausea ;
feeling of dry mouth;
And .

The following undesirable effects occur infrequently:

mental excitement;
abdominal pain;
skin rash , itching ;
asthenia .

Undesirable effects that are rare:

peripheral edema;
hives ;
increased levels of functional liver tests (activity of transaminases, alkaline phosphatase, bilirubin concentration);
weight gain;
, ;
aggression ;
sleep disorders;
convulsions ;
hypersensitivity reactions.

Very rarely there are such consequences of treatment with Zyrtec:

taste disorders;
fainting conditions;
visual impairment: blurred vision, , disturbances of accommodation;
dysuria , ;
thrombocytopenia ;

The following reactions may also occur (no data on how common they occur):

promotion ;
urinary retention ;
vertigo ;
suicidal ideas;
memory impairment, even before .

Instructions for use of Zyrtec (Method and dosage)

The dosage depends on the patient's age. The condition of the body is also taken into account, for example the presence and degree renal failure .

In most cases, the daily dose is taken at one time. Directions for use: inside (for both forms).

The attending physician decides how many days to take the drug, taking into account the diagnosis and severity of the allergic reaction.

Zyrtec drops, instructions for use

Dosage of the medicine in drops depending on age:

adults and children over 6 years of age are prescribed 10 drops of the medicine as an initial dose, then, if necessary, it is increased to 20 drops;
children under 6 years of age, but over 2 years of age, are advised to take 5 drops twice a day or 10 drops at a time;
at the age of one to two years, take 5 drops 1-2 times a day;
drops for children from six months to a year are prescribed in a dose of 5 drops;
patients with liver failureyu the dosage is selected taking into account creatinine clearance. If it is a child, its weight is also taken into account when adjusting the dose.

Zyrtec tablets, instructions for use

The dosage of tablets is calculated as follows:

adults and children over 6 years old - from half a tablet (initial dose), the dose can be increased to a tablet per day;
Before 6 years of age, medicine in tablet form is not prescribed.

Instructions for use of Zyrtec for children

The summary of the drug provided by the manufacturer shows that only Zyrtec drops are used to treat pediatric patients. In this case, drops are dosed for children depending on age.

Dosage for children:

5 drops from 6 months to one year;
5 drops 1-2 times – from 1 to 2 years;
10 drops daily at a time or divided into two doses - from 2 to 6 years;
Older children are prescribed the same dose as adults.

The way to take the drops for children is slightly different from the method for adults. Children can take the drops as syrup (orally, diluting a little with water), but up to one year, Zyrtec can be prescribed as nasal drops. In this case, they are instilled drop by drop into each nostril, after cleaning them first.

Treatment continues until symptoms stop allergies .

Overdose

An overdose occurs when a single dose of medication is taken several times higher than the daily dosage.

Symptoms characteristic of taking about 50 mg of the drug (5 tablets or 100 drops):

confusion , stupor ;
pronounced sedative effect;
fatigue;
diarrhea ;
urinary retention ;

If a higher than usual dose has been taken, you must immediately rinse the stomach or induce vomiting. You can also give . There is no specific treatment, so only symptomatic treatment is possible. Carrying out ineffective in case of overdose.

Interaction

Interaction of Zyrtec with other drugs:

With Thiophylline – the total clearance of cetirizine decreases by 16%;
With Ritonavir – The AUC of cetirizine increases by 40%, and Ritanovir decreases 11%;
With , Bupreporfin – mutually enhance each other’s effect, which manifests itself in depression of the central nervous system;
With – mutually enhance the effect on the nervous system, as a result of which its functioning deteriorates and the reaction speed decreases.

Terms of sale

Over the counter.

Storage conditions

Store in a cool place, out of reach of children.

Best before date

Special instructions

Particular caution should be exercised when prescribing the drug to persons with factors predisposing to urinary retention (spinal cord injury, prostatic hyperplasia), since cetirizine increases the likelihood of this complication.

During treatment, it is advised to avoid driving and activities that require high concentration and high reaction speed.

The drug should not be prescribed to children under one year of age who are at high risk of developing sudden death syndrome (at , smoking mother or nanny, premature babies, etc.).

For children

Zyrtec for children is used very widely. Reviews of Zyrtec drops for children show that if it is used as recommended in the instructions, the effect will be high and the risk of undesirable consequences will be minimal.

Newborns

The drug is contraindicated for use in infants under 6 months of age.

With alcohol

It is not advisable to combine alcohol and Zyrtec, as alcohol increases the risk of depression of the central nervous system.

Zyrtec during pregnancy and lactation

Studies regarding the effects of taking the drug during pregnancy have been conducted only on animals. No effects on fetal development or the course of pregnancy were found. But due to a lack of information on safety for the human fetus, the medicine is not prescribed to pregnant women.

Fenistil;

Analogs are available in dosage forms such as tablets, syrup, ointment (for skin manifestations allergies ), drops.

The price of Zyrtec analogues for children is usually lower than the cost of Zyrtec, but in most cases it has higher bioavailability and absorption rates. It has also undergone more clinical studies, which indicates higher safety of use.

Which is better – Zyrtec or Claritin?

Claritin has a more pronounced effect, has fewer side effects, as it belongs to the third generation. But the active ingredients are different, so you need to focus on which one is best suited in each individual case.

Which is better – Zyrtec or Fenistil?

Fenistil has more contraindications. Zyrtec works longer and more selectively.

Which is better - Cetirinax or Zyrtec?

The active ingredient is the same, but Cetirinac is a generic, not an original drug, and is available only in tablet form, which creates difficulties when treating children. The cost is lower than Zyrtec.

Zyrtec or Zodac – which is better?

The difference between Zyrtec and Zodaka small. Bioavailability Zodaka slightly higher than Zyrteca (99% and 93%, respectively). Zodak is also eliminated from the body 2-5 hours faster.

Zodak costs less. But the original and more researched drug, and, therefore, with fewer contraindications, is Zyrtec.

Which is better – Zyrtec or Erius?

Zyrtec belongs to the second generation of drugs, and Erius to the third. It is not able to penetrate the blood-brain barrier, therefore it does not cause side effects associated with sedation and does not impair coordination of movement. But it costs much more.

Anonymous

Please help, my husband really needs a boy. I have an eldest daughter from a previous marriage, then we had a daughter together. Now the husband is directly demanding a boy. I’m even ready for IVF with implantation of an embryo of the desired sex. But my gynecologist told me that IVF is definitely not for me, hormonal preparation will have a very bad effect on my blood vessels and blood pressure. Up to a stroke. I also told my husband about this. He is going to take me to the border because in our clinics (we were in two) they said gender transfer can only be done for health reasons, and my health may not be able to tolerate IVF. My sister says that we need to try traditional methods. And I'm scared. If the first ultrasound doesn’t show the gender, then I don’t know what will happen at the second one if it’s a girl again. What if the husband will be so against the girl that... Or will he then send for a fourth? Help! There are some ways to count days, I once read about the right day of conception! For the desired floor. If anyone has used this method and if it worked for you, please tell me!

155

Lyubakha

Hello girls.
In general, I began to think about an au pair (I am alone with three children recently). In principle, I manage to do everything, but it costs me nerves and a lot of physical effort... I always look like a cornered horse.... I can’t forget about putting on makeup and styling my hair in the morning.... and so on all day.. .poke point, point point. To make life a little easier, I’m thinking about finding an assistant to do the cleaning at least once a week. My first problem in my head... is that I’m really ashamed to seek help around the house, since I’m physically healthy and, in principle, I can do everything myself (I’m doing it now too). My second problem is in my head....will I be satisfied with the cleaning? After all, a stranger is unlikely to clean as well as at home. I'm not really a neat person, but I never have a mess at home....there are no scattered toys, clothes or tumbleweeds of dust)). I resisted washing the floor with a mop for a long time, because I thought (and still do) that it was just smearing dirt from corner to corner... but physically I simply won’t be able to wash 100 square meters with my hands... and my children won’t give me that much time. cleaning. On the one hand, I think it would be great to take the kids and go for a walk while the house is getting organized. On the other hand, suddenly you’ll have to wash everything again... and that’s not a small amount of money.
In general, these are all my cockroaches, I agree. Who has au pairs and similar cockroaches... how did you choose, by what criteria, a cleaning lady? How often did you have to change it, if necessary?

147

Everything will pass

Below is a topic about gifts for an 8 year old child for the New Year. There are many answers. They say let him write to Santa Claus. Do your children really still believe in Santa Claus at the age of 8 or is this a smart. cunning. children's move. marketing. I say I believe it. Let them think so, I’ll write it. And then how will their parents’ finances improve????

114

Nata Ser

I just don’t understand how this can be? About a year ago we moved into a new apartment, finally a big one. The renovation was done before us, I can’t say that everything is perfect, but overall it’s fine. And somewhere around the month of August, the neighbors above us began renovations: the humming and drilling was terrible, the roaring noise, but everything was strictly during working hours. Now, as I understand it, finishing work is going on there, because although there is noise, it’s different: tapping, etc. But this is not the problem, a month ago, on the same Sunday, a neighbor from below came to us and said that there was a leak from the ceiling in his bathroom. At that time, no one was washing in our bathroom, but they had used it before, maybe half an hour ago... We let him in, he made sure that everything was dry under the bathtub and in the toilet too. But today the doorbell rings again, it’s leaking again. Yes, I was just in the bathroom and today everyone was there alternately. But, I took a bath yesterday and before that on different days, and nothing flowed either. And again everything was dry. She didn’t let her neighbor in because she was in a negligee and was talking to him through the door. He is indignant and demands that we call a plumber. But what do we need it for? Everything is dry here. Could this be due to the renovations being carried out by the neighbors above? And who should call a plumber anyway? It’s not difficult for me, but I don’t understand why?

More and more often we have to deal with allergies. Children are most susceptible to it, whose bodies sometimes react painfully to getting to know the outside world. Babies are bothered by rashes, itching, watery eyes and runny nose. To help a small patient, pediatricians prescribe antiallergic drugs. Today we will talk about Zyrtec.

Zyrtec has a strong antihistamine effect, but causes virtually no side effects.

In what cases should it be taken?

Zyrtec is a remedy that eliminates signs of allergic reactions. It approved for use in children over 6 months and adults. The drug is prescribed by the doctor after diagnosis:

hay fever, or hay fever;
Quincke's edema (develops in a few minutes);
allergic dermatoses (, and others).

For non-dangerous allergy symptoms, you should first see a doctor, since after taking Zyrtec it will be more difficult for the allergist to make a correct diagnosis. These symptoms may include:

rash;
skin itching;
redness of the skin or conjunctiva (inflammation of the mucous membrane of the eyeball);
lacrimation;
constant sneezing;

Zyrtec can be given to a child without a doctor's prescription only once to eliminate signs of a dangerous, rapidly developing allergic reaction - Quincke's edema.

This will be a kind of first aid, after which you need to call an ambulance.

Christina writes in her review:

“The baby’s fingers have become thick, like an adult’s! I got scared and called an ambulance. Upon arrival, the doctor asked me what kind of help I provided. But I didn’t give her anything because I didn’t know how to help. It turns out that it was possible to give the child Zyrtec drops. We had them in our first aid kit. The ambulance crew especially frightened me because if there was swelling of the larynx, my daughter could suffocate. From now on, I will give drops for any allergy symptoms.”

Your doctor will prescribe the correct dosage.

Release forms

Zyrtec comes in two forms:

Drops. A clear, colorless liquid that smells like vinegar.
The tablets are oblong in shape with a line in the middle. The white shell is often marked Y/Y on one side.

For infants and young children, it is convenient to give the medicine in the form of drops, because they don’t know how to swallow pills yet. For older children, the drug can be given in any form.

The drops are sometimes mistakenly called syrup, which confuses parents in their search.

The mother of two-year-old Petya left the following review:

“You can’t force your son to take medicine because it doesn’t taste good. He only opens his mouth if it's sweet syrup. I once heard that Zyrtec is also available in syrup. But no matter what pharmacy I went to, they told me that there was no such form. One of the pharmacies told me that syrup means the same drops.”

Drops can be added to food or water.

Composition and action

The composition of Zyrtec is indicated in the instructions supplied with the medicine (). The active substance of the drops is cetirizine dihydrochloride (10 mg in 1 ml of medicine).

Auxiliary components include:

sodium salt of acetic acid;
magnesium salt of stearic acid;
propylene glycol;
glycerin alcohol;
methylparabenzene;
sodium saccharinate;
titanium dioxide;
propylparabenzene;
distilled water;
Glacial acetic acid.

Such a long list can alert parents: why does a child need so much chemicals? But there will be no harm, because All ingredients are contained in very small quantities, and the main volume is water. But these substances help the active component act quickly.

To understand how Zyrtec works, you need to understand the mechanism of allergy development. After a person comes into contact with an allergen, antibodies are produced. If contact continues, they fight the allergen, settling on the walls of immune cells. This leads to the formation of histamine, a substance that increases cellular permeability. Fluid penetrates the membrane of such cells, and edema develops. Additionally, histamine affects receptors, causing rash, redness and itching.

To get rid of edema, it is necessary to reduce the permeability of the cell membrane - this is exactly what the active substance Zyrtec does. And to get rid of a runny nose and skin reactions, it is necessary that the receptors do not react to histamine. After taking the medicine, cetirizine dihydrochloride begins to act on them. There are no free receptors left in the body that could react to histamine: they are all already occupied. Therefore, signs of allergies disappear.

Zyrtec does not cure allergies, it only helps relieve symptoms.

How to give Zyrtec to children?

The dosage of Zyrtec depends on age:

At 6-12 months - 5 drops (2.5 mg) per day (single dose).
Children from 1 to 2 years old - 5 drops (2.5 mg) up to two times a day at any time, but with an interval of 12 hours.
At 2-6 years old - daily dose of 10 drops (5 mg). Take once a day in full or twice 5 drops.
From 6 years - daily dose of 20 drops (10 mg). Let's take 20 drops once or 10 drops twice a day.

No allergies - no problems!

The effect of the medicine does not depend on the time of food intake, since this does not affect the absorption of the active substance. The only difference will be that with an empty stomach, the drug will enter the blood within 20-60 minutes, and with a full stomach, in an hour or two. Zyrtec drops for children can be dripped directly into food or a bottle of milk or formula.

The effect of the medicine lasts for three days, but over time it weakens. Its effect is maintained by taking it up to one or two times a day.

Zhanna writes in her review:

“I read that Zyrtec works for three days after taking it, and I decided not to give my baby chemicals every day. Why, if this can only be done once every three days? But already on the second day I noticed new rashes on my skin. The area was small, and the rash was mild. But it’s better without it at all and without itching. Since then I have been giving it as indicated in the instructions for use - 1-2 times a day.”

The length of time you take Zyrtec depends on the cause of the allergy. For short contact with the allergen, it is enough to take the drug for two to three days. If these are seasonal allergic reactions, then the drops should be taken until the exacerbation ends. The duration of the course is determined by the doctor.

The allergy season in our country lasts from mid-April until the first frost.

Side effects and contraindications

Possible side effects (occur in 1% of cases or less):

lethargy and drowsiness;
dizziness and headache;
migraine;
gastrointestinal disorder;
rash, itching and urticaria, Quincke's edema (in case of intolerance to substances contained in the medicine).

Zyrtec is contraindicated for use in the following cases:

children under 6 months of age (with the exception of a life-threatening allergic reaction, when the benefit of Zyrtec will be greater than the possible risk);
individual intolerance to the components of the drug;
pregnancy;
lactation period (the medicine penetrates into milk).

Overdose

When taking a large dose (from 50 ml, which is equal to 5 bottles, for adults and from 10 ml, which is equal to 1 bottle, for children), an overdose occurs. Her symptoms:

lethargy, desire to sleep;
irritability;
panic;
rapid heartbeat;
drying of the oral mucosa;
and lack of urine;
pupil dilation.

In case of overdose, consult a doctor immediately.

What to do:

Stop Zyrtec.
Rinse the stomach.
Give activated carbon (1 tablet per 10 kg of body weight).
Call an ambulance.

Where are Zyrtec drops made?

Manufacturers:

UCB Farchim (Switzerland);
UCB Pharma (Belgium);
UCB Pharma (Italy).

The price of drops depends on your region and ranges from: 300-350 rubles for a 10 ml bottle.

What to replace it with? - review of analogues

If the pharmacy does not have Zyrtec, it can be replaced. Buy another drug with an identical effect. Here's a brief overview of the analogues - you can use any of them as an alternative:

. The same composition, but the drug is produced in the Czech Republic. It is distinguished from Zyrtec by the technology of processing raw materials during production and the use of other auxiliary elements in the composition that do not affect the action. The price is lower - 200 rubles per 20 ml bottle. Taking Zodak is only permissible from 12 months.

Zodak for children is available in the form of drops, tablets and syrup.

Parlazin. Similar composition, but made in Hungary. It also costs less - about 250-270 rubles per 20 ml bottle. Can be given to children from 12 months.
Cetirizine. The composition is similar, but the drops are of either Swiss or German origin. Do not give to children under 1 year of age.

Lyudmila from Moscow says:

Moms, remember that Zyrtec for allergies is used only to eliminate symptoms. The disease itself remains, and it will haunt the baby all his life if the necessary measures are not taken. To defeat the disease, you need to identify the allergen and eliminate it from the child’s life. Strengthening the immune system and desensitizing therapy, which should be recommended by an allergist, will help.

Anonymous

155

Lyubakha

147

Everything will pass

114

Nata Ser

In today's world, more and more children are suffering from allergy symptoms. Unexpected reactions of the body to certain stimuli occur even in children. Allergy symptoms include not only a rash on the body, but also watery eyes, runny nose, and sometimes a suffocating cough. Pharmaceutical companies have developed a drug that is reliable, non-drowsy (at the right dosages) and has minimal side effects. It is called Zyrtec drops, instructions for use for children will be discussed in this article.

Composition and release form

Today, Zirtec can be found in pharmacies in 2 forms: drops, which are also called solution or suspension, and tablets.

Drops are a homogeneous transparent liquid, dispensed in bottles of 10 or 20 ml. The bottle itself is made of dark glass to avoid direct sunlight. There is also a lid - a dropper, for convenient dosing of the drug.

The tablets are oblong in shape, scored and marked.

The active component of the drug is cetirizine. 1 tablet or 1 ml of drops contains 10 mg of the main ingredient. It also contains additional components that do not have a therapeutic effect. Among them is acetic acid, which gives the drug a somewhat unpleasant odor and taste.

Operating principle

Zyrtec drops tend to block histamine receptors, which are located on the surface of cells and cause allergies. When the skin is irritated, histamine is released.

The drug isolates it and prevents its effects on the body. However, Zyrtec is able not only to block histamine receptors, but also to block the new release of this substance.

The drops do not promote the bronchoconstrictor reflex, therefore they are approved for use in children with bronchial asthma.

Zyrtec has an anti-inflammatory effect, reduces swelling, as well as smooth muscle spasms.

The drug is effective as an independent medicine, and it is also often prescribed in combination with other drugs.

The effect of the medication begins 20 minutes after administration. Its maximum concentration is observed 1 - 1.5 hours after administration. The drops have high bioavailability and are completely adsorbed by the walls of the gastrointestinal tract.

After stopping the use of Zyrtec, the effect persists for another 3 days.

Addiction and weakening of the effects of the medication do not develop.

Zyrtec has the following therapeutic effect on the body:

is the prevention of allergic diseases;
eases the course of allergies;
relieves itching;
weakens lacrimation, reduces the amount of nasal discharge;
relieves swelling and redness;
eliminates rashes.

Indications for use

Most patients understand what Zyrtec is used for. However, it is not always clear which allergies the drug helps with. The instructions state that the medication can be used in the following cases:

allergic rhinitis and conjunctivitis, regardless of the season;
hay fever therapy;
hives;
Quincke's edema;
any allergic skin lesions with itching and rashes;
allergic cough;
drug allergy.

When is it prescribed?

For any skin rashes – relieves inflammation and swelling, eliminates peeling;
When vaccinated - prescribed to prevent allergic reactions to the vaccine;
For insect bites – relieves inflammation and swelling, relieves intoxication from bee stings;
For adenotonselectomy (surgery to remove adenoids) - prescribed in preparation for surgery;
For coughs and runny noses, in combination with antitussive drugs, it thins mucus, relieves swelling and bronchospasm;
For a runny nose - prescribed to ease breathing in combination with other drugs;
For chickenpox – relieves itching and inflammation.