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Dermatology, antifungal drugs for dogs. Shampoo for dogs "Doctor": features of use and side effects Environmental treatment

  • dermatitis of various etiologies;
  • folliculitis;
  • demodicosis;
  • seborrhea;
  • infections of a fungal or bacterial nature;
  • sarcoptic mange;
  • skin diseases resulting from hormonal imbalances in the body.

Effect of shampoo

Mode of application

Despite the fact that the detergent has a gentle effect on the skin and mucous membranes of the body, it is necessary to use it carefully and prevent the shampoo from getting into the mucous membranes of the eyes or mouth. Doctor dog shampoo is used daily for 7-10 days, or with a break of 1-3 days.

After use, you may notice a slight whitening effect. This fact does not cause any harm to the animal and after some time the bleaching will disappear. In order not to harm the animal’s skin, the duration and frequency of treatment must be observed.

Side effects of shampoo

After testing the detergent, no side effects on the animal’s body were found. The only problem may be peeling, which occurs with prolonged use of the detergent. After completing the course of treatment, the peeling will disappear.

Doctor shampoo with tar for dogs is prohibited for use in cases of individual intolerance to certain components of the shampoo. Therefore, before the first use, it is better to try its effect on a small area of ​​the animal’s skin to prevent the development of a severe allergic reaction.

The tar included in the composition provides anti-inflammatory and antimicrobial effects. In veterinary practice, “Doctor” shampoo for dogs is becoming increasingly popular. Its price allows any owner to purchase the product. Following all the veterinarian's recommendations will prevent the development of allergic reactions and skin peeling.

Therefore, before using a new shampoo, you should definitely consult a doctor and, if necessary, conduct an examination of the animal for tolerance to the substances included in it.

There are many types of fungus in dogs. Some of them are caused by pathological growth of normal microflora (a set of fungal organisms) on the skin, mucous membranes and internal organs. Weakened immunity after a severe or protracted illness, pregnancy, early age of puppies, the period after vaccination are the most conducive conditions for the growth of mycoflora. Normally, these mushrooms benefit their “carrier,” but when there are too many of them, they cause harm to him.

Mycoses affect almost all parts of the animal’s body - paws (fingers, pads, interdigital space), tail, ears, mucous membranes of the mouth and genitals, nose, eyes, skin over the entire surface, skin appendages (claws, fur, sebaceous glands), internal organs. Some types of fungal organisms can grow anywhere, while others can only grow in certain places. Specific microflora develops in the mouth, nasal passages, and vagina of the animal. Pathogenic microflora forms on any part of the body.

Fungus in dogs and its development periods

Fungus on a dog's paws usually develops in the spring and autumn, when the weather is slushy and damp. In some areas of the country, where there are damp, rainy summers or warm, snowless winters, mycosis on the paws is diagnosed in animals all year round. The dog licks and chews its paws, limps or pulls up its paws. Externally, the owner may find that:

  • claws peel off, change their color and/or structure,
  • the pads peel, bleed, are covered with cracks or wounds,
  • the fingers are red, swollen, left without hair, the interdigital space is red, the skin in it is exfoliating, peeling off.

Any of these signs is a reason for an urgent visit to the veterinarian. An advanced form of mycosis on the paws leads to loss of hair, changes in the dog’s gait due to constant lameness, and the animal gnawing and licking itchy places. When a dog constantly licks or chews a fungus-infected paw, harmful microorganisms enter his digestive tract and can begin to multiply there. Thus, the external disease becomes internal and is much more difficult to treat. In addition, self-bites and scratches on the paws can begin to become inflamed, infected, and fester. Then the fungal infection will be complicated by an abscess and even sepsis.

Fungus on an animal's tail

Mycosis of the tail in a dog is usually not limited to one area and spreads to the skin of other parts of the body - most often to the back and sides. If a dog combs its tail excessively, chews or licks it, it runs the risk of introducing pathogenic fungi into its mouth, digestive tract, and also into the genitals if, after licking the tail, it licks the prepuce or genital slit. This is especially dangerous for pregnant bitches due to the risk of infection of fetuses, young puppies and very old animals with chronic diseases or weakened immune systems. Mycosis lesions on the tail are a type of skin fungus.

Skin fungus in dogs is the most common reason for owners to contact a veterinary dermatologist. The disease is often contagious and caused by fungal organisms - normal, opportunistic and pathogenic. Often accompanied by a bacterial or viral infection.

Mycosis on the ears

Ear fungus in dogs is not a contagious disease and develops against the background of a general weakening of the immune system with the participation of fungi of the genus Candida and Malassezia, which are characteristic of the dog’s skin. These are yeast fungi that are constantly present in the ears and other parts of the body of animals. Under favorable conditions, yeast fungi begin to actively multiply and change the myco- and microflora in the external auditory canals.

The impetus for the pathological growth of a fungal colony is most often a bacterial infection. Fungal organisms perceive bacteria as a threat and begin to fight them. Also, the proliferation of microflora is often caused by ear mites - otodectosis. In this case, it is necessary to treat both bacterial, tick-borne, and fungal infections.

Exudate forms in the ear canal, which dries out, forms crusts and clogs the passage. The dog hears worse, becomes more nervous and even aggressive. If the nerves are affected, the dog will also experience nervous seizures, reminiscent of rabies or epilepsy.

Failure to adequately treat ear fungus can lead to impairment and even loss of hearing in your dog. In addition, constant scratching of the ears is complicated by infection with bacteria and viruses, as a result, inflammatory and purulent-inflammatory processes of the ear canal, eardrum, and external auricle.

Ear fungus in dogs has the following symptoms:

  • the dog shakes its head violently, as if trying to shake out droplets of water or a foreign body from the ear canal,
  • the animal scratches its ears and head with its paws or rubs its head on objects,
  • the ears have acquired a reddish color, a vascular network has appeared on the auricle (not always),
  • on the ears there are signs of alopecia - pathological loss of hair and the appearance of short thickened or, on the contrary, thinning hairs in places of bald patches.

If you notice something like this in your pet, the owner should take him to a veterinarian for tests and scrapings. Confirmation of mycosis requires urgent initiation of treatment. However, even if the dog’s ears are affected not by a fungus, but by another infection, they still need treatment due to the risk of complications or the development of dermatomycosis.

Treatment of mycoses in dogs

How to treat fungus in a dog can only be decided by a veterinarian after a thorough examination of the four-legged patient. Some types of fungal organisms glow green when irradiated with an ultraviolet lamp. To diagnose other types, the doctor takes scrapings from the location of the fungi and does a culture in the laboratory.

Only after a diagnosis of mycosis has been made and the causative agent has been accurately identified, medications are prescribed. You cannot use anything to treat your pet for a fungus on your own, on the recommendation of a neighbor, or because this remedy helped last time, since what is effective against one type of microorganisms does not work at all against another type.

Antifungal medications for dogs are available in various dosage forms:

  • Shampoos with antimycotic components - nizoral, clotrimazole, ketoconazole. These shampoos have a therapeutic effect, but they can also be used to prevent mycoses. In particular, such a shampoo is simply necessary after a dog has come into contact with an infected animal, after swimming in an open body of water, especially in one where the water “blooms”, after wallowing in a puddle or the excrement of other animals, as well as after hunting a fox, badger, etc. with which the hunting dog entered the fight. Wild animals are potential sources of fungal and other infections.
  • Antifungal vaccines - Vakderm, Polivak, Microderm. They are used for the prevention of mycoses, as well as for the treatment of already diagnosed diseases. Vaccination is carried out in two stages with an interval of two weeks. It is necessary to take into account the breed characteristics of the pet, because some hunting breeds develop allergies to antifungal vaccines and even develop an abscess at the injection site.
  • Antifungal sprays - zoomicol, fungil, which are sprayed on the affected areas or even on the entire surface of the animal’s body. Sprays penetrate well even through long and thick fur.
  • Ointments with components against fungal microorganisms. They are applied to the lesion, slightly extending beyond its area. If necessary, apply a loose bandage. For a better therapeutic effect, it is worth cutting or shaving the hair from the treated area.
  • Birch tar, a previously known folk remedy, gives a good effect. This is a very unpleasant and strong-smelling liquid. Tar is completely unsuitable for cats due to the risk of developing a severe allergic reaction. But it is safe for dogs and helps them well, relieving itching, eliminating all pathogens and drying out bite wounds and scratches.

Sometimes dog fungus spreads so much throughout the dog's body that the affected areas are difficult to treat. A long-haired dog should be cut as short as possible if he does not live outside in the winter or does not participate in exhibitions. As a last resort, long hair should be thoroughly combed with a brush and comb, untangled and matted hair removed. If possible, you should use a furminator to remove the faded undercoat. If weather conditions allow it and a long-haired dog does not need to perform at an exhibition, then it is worth profiling, in other words, thinning out the thick coat.

To prevent self-biting and licking of lesions, as well as licking of medicinal ointments, it is advisable to wear a protective collar on the animal. Such collars are sold in veterinary clinics and pharmacies, in pet stores, and are selected according to the volume of the dog’s neck and the length of the dog’s muzzle.

Causes and prevention of fungal diseases in dogs

Fungal microorganisms exist in absolutely all biological niches: in salty and fresh water bodies, on any type of soil, on any substrate, including living organisms, in dry and wet, acidic and alkaline environments. Therefore, it is not at all easy to fight them. Fungi are very tenacious and are capable of completely restoring their colony in a short time, like Leishmania.

The reasons for contracting a fungal infection are numerous: contact with an infected animal, contact with the excrement of a sick dog, swimming in a body of water with stagnant and “blooming” water.

One of the main conditions for the treatment and prevention of mycoses in dogs is to clean the room where the dog lives, the enclosure, and bedding from sources of infection. It is necessary to thoroughly treat all surfaces with cold water and dissolved chloramine. The floor, walls, and furniture sets need to be treated. It is better to entrust upholstered furniture on which a dog can lie, carpets and rugs to a professional pest control service. But it is also possible to clean them yourself with a solution of chlordesine.

Toys, cages, bowls and other animal accessories must be treated with formaldehyde and thoroughly rinsed to remove any traces of the substance. Bedding, soft toys, fabric collars, leashes and harnesses should ideally be replaced with new ones. But as a last resort, they can be soaked in very hot water with baking soda dissolved in it, and then rinsed.

If the animal is kept in the yard, then the enclosure and kennel should be treated with a disinfectant solution, the bedding and the top layer of sand or crushed stone flooring in the enclosure should be replaced. For preventative purposes, bedding and bulk coverings in the yard must be regularly changed or cleaned of dirt and disinfected. It is necessary to wash outdoor shoes daily and put them out of reach of the dog so that the pet does not play with them.

Fungal diseases in dogs cause considerable economic damage, since they take a long time to treat, not every medicine can destroy fungi, and one should not forget about the possibility of transmitting the pathogen to humans. Many of these diseases are combined under the name “dermatophytoses”: in dogs it is a whole complex of pathologies, the causative agents of which are often related to each other.

In dogs, ~70% of cases are caused by Microsporum canis, 20% by M. gypseum, and 10% by Trichophyton mentagrophytes. Interestingly, at least 98% of cases in cats are caused by Microsporum canis. Wood's lamp useful in making a preliminary diagnosis in dogs, but cannot be used to rule out this type of infection (due to some risk of false-negative reactions).

An accurate diagnosis can be made only on the basis of studying a grown culture of the pathogen (on a nutrient medium). To make the diagnosis process easier, you can use... a regular toothbrush. New, really. It is passed over the affected surfaces, trying to ensure that the bristles adhere as tightly as possible to the skin. After this, the brush is “shaken” over a Petri dish with a nutrient medium. Practice shows that with this approach the pathogen will definitely be scraped off and get onto the substrate.

Symptoms of dermatophytosis in dogs are quite variable. More often Puppies and weakened pets are sick. Local areas may appear, which, among other things, become covered with crusts. Often lesions are located on the face, near the ears and eyes. Sometimes there are cases of asymptomatic disease, when the dog is a carrier of the infection (this is very dangerous, because people can also get sick).

There are known situations where pathogens of dermatophytosis caused the development nodular In this case, skin “nodules” appear on the skin of a sick animal, that is, papules, in the literature called dermatophytic granulomas or pseudomycetomas. Some experts suggest that this development of the disease can be explained by an initially existing genetic predisposition.

But still, dogs are characterized by the appearance of hairless, “” areas of skin. The disease is regional or generalized folliculitis and with papules and is somewhat less common, although this is quite possible. Generalized ringworm in adult dogs is usually accompanied, especially by endogenous or iatrogenic hypercortisolism. Very often, bacterial folliculitis and dermatitis are involved in the pathogenic process.

Read also: Joint diseases in dogs: basic information and treatment methods

The virulence of pathogens is quite high. Transmission of infection – contact, and this does not necessarily have to be contact between a sick and healthy animal: it is enough for the dog to simply lie down in the place where the sick animal was previously located. The “secret of success” of pathogenic fungi lies in their effect on the fur and skin of a sick dog.

Hair becomes very fragile, easily breaks and falls. Thousands and millions of fungal spores fall along with them. As soon as they get on the skin of a susceptible animal, they begin to germinate, resulting in the development of a disease.

Therapeutic measures

Ringworm (provided the pathogen is not particularly virulent) in dogs with short hair may end spontaneously, but still you shouldn’t hope for it. The main reason for this is that the disease is quite mild transmitted to people. By the way, the owner of a sick animal must constantly remember this.

Interesting fact. There is not a single “official” study that confirms this, but trimming sick pets bald (or close to it) significantly reduces the time of illness. However, veterinarians themselves do not need such research, since in practice it has been repeatedly proven that trimming (especially long-haired dogs) significantly simplifies the treatment process itself and, therefore, increases its effectiveness. It is believed that “forced baldness” should be accompanied by daily treatment with a 0.2% fluconazole solution.

This approach will significantly speed up the treatment process and reduce the likelihood of transmission of infection to humans. In practice they are often used in solutions of miconazole, fluconazole, and is also used on the basis of miconazole and chlorhexidine. But all this is effective only as an adjunctive therapy, and not as a primary treatment. However, there are many medications intended for the primary treatment of dermatophytoses, which are based on the same miconazole and itraconazole.

Please also note that some of these drugs may cause (constant drooling) in animals. Also, frequent use of shampoos can lead to rather interesting results, like false positive or false negative results of serological tests.

Read also: Brain tumor in a dog - signs and symptoms of the disease

Systemic therapy for severe cases

In all cases where the course of the disease is severe, or there is a tendency for the process to worsen, treatment of dermatophytosis in dogs should be systemic. For this, itraconazole, fluconazole, terbinafine, ketoconazole and antibiotics from the griseofulvin group are used.

As for the latter, it is recommended to use them daily for dogs, at a dose of 25-100 mg/kg. This dose can be divided into several doses, or given once. If antibiotics are used not in injection form, but in the form of tablets for oral administration, then they are given simultaneously with fatty food (for better absorption and minimizing the harmful effects on the gastrointestinal tract).

It is very important to maintain accuracy dosage and vary it depending on the weight and physiological state of the sick animal. Medicinal griseofulvins are also well suited for use in veterinary medicine.

If they are used for too long, neutropenia and other reactions from the hematopoietic system may develop. There are also cases described where long-term use of these antibiotics may have led to the appearance of. However, there is little information about this, but the fact remains that you should not uncontrollably “stuff” your pet with antifungal drugs, as this can end very badly!

Other effective treatments include itraconazole 5-10 mg/kg per day for 28 days. The drug can also be used courses“week after week”, when the animal is given medicine for 7 days, and for the next seven days its body “rests” from its effects. The following have proven themselves to be effective: ketoconazole (5-10 mg/kg per day), terbinafine (30-40 mg/kg per day), fluconazole (5-10 mg/kg per day). The latter, by the way, is used only in the mildest cases, since studies show its low effectiveness against most pathogenic fungi.

It is believed that terbinafine is most effective for many dermatophytoses. After just two weeks of use, clear signs of improvement are often visible, after which the dose of the medicine can be reduced (at the discretion of the veterinarian). But with this drug everything is not so simple, there are side effects. In particular, it often leads to development (nothing in the dog), and in some cases the animal has to be fed for a very long time either through a gastric tube, or its life is maintained by infusing nutrient solutions intravenously.

Fungus in dogs, or dermatophytosis disease, is an illness of infectious etiology that requires seeking veterinary help. Not a single pet is insured against this disease, regardless of the conditions of detention. It is important for owners to identify the disease in time, based on its symptoms and primary signs.

Photo of fungus in dogs

There are many types of fungi, but only a few of them are the causative agents of dangerous infections in the body of dogs. Infection can occur through contact with another animal or walking on grass that contains pathogens. Even a dog that uses the litter box can become infected, since fungi often enter the house with the owners’ shoes.

In addition to pathogenic species, there are also opportunistic fungal pathogens. They can always be present in the animal’s body, but the dog only gets sick under certain circumstances - weak immunity, hypersensitivity, etc. These types of fungi are not contagious; they live on the skin, but do not cause harm.

At risk for dermatophyseal disease are young individuals, dogs that have had an illness or surgery, have problems with the immune system, and animals with a tendency to develop diseases.

Factors contributing to the development of the disease are an unbalanced diet and high air humidity. The growth of the fungus increases on the skin that does not receive enough air, covered with matted hair and a layer of dirt. Fungi also multiply quickly in dogs that are washed very often, since this procedure eliminates sebum and reduces the skin's protection from external pathogens. In addition, the animal’s body cannot resist the disease after taking drugs that suppress the immune system.

It is possible to identify many more factors that contribute to fungal diseases, but even in their absence there is a risk for the animal to become infected with pathogenic fungi.

Main signs of fungal infection

Until the origin of the causative agent of this condition is clarified, there is a risk of infection in humans and other animals.

Among the main symptoms of fungus are the following:

  • the disease begins to develop from one to three small spots;
  • from the affected areas, in some cases it seems to be cut off, leaving a short length;
  • the resulting spots can remain the same size for a long time or grow, depending on the type of pathogen and the strength of the protective mechanisms of the immune system;
  • the skin at the site of the lesion becomes gray or red;
  • if you look closely, you can find a white or grayish coating on the hair follicle;
  • the affected area is covered with flakes or exfoliating scales, which may fall off the skin or adhere tightly.

Without timely treatment, the size of baldness increases. The fungus begins to grow into the deeper layers, which provokes various kinds of complications. In the severe stage of the lesion, the dog completely loses its coat, which is not restored for a long time.

Often the fungus affects the pet's paws, in this case inflammation and cracks are observed in the interdigital space and on the pads. The claws may also become affected, causing them to become yellow and crooked. It hurts the dog to step on its paw and it begins to limp.

Treatment of fungus in dogs

Most fungal infections are accompanied by itching, the degree of which depends on the type of pathogen. In some cases, the dog may scratch the skin until it bleeds. In this case, experts recommend that before visiting the veterinarian, give an antipruritic drug, such as Stop Itching, and use a protective accessory - a collar or blanket, since skin injuries caused by fungus provoke secondary infection.

Any wounds that appear should be treated with an external agent that has an antiseptic effect. Miramistin is suitable from a person's first aid kit, or Migstim must be purchased at a veterinary pharmacy.

During a visit to a specialist, you should clarify where the skin was treated with the drug, since tissue from these areas is not suitable for analysis.

If the fungus affects the paw pads, it is necessary to protect your pet's paws from moisture. During the walk, you can use special protective shoes, and after washing the paw, dry it with a hairdryer. You should not let your dog chew on areas affected by the fungus.

Chronic form of fungal infection

Long-term infection proceeds more calmly. Hair shedding is observed from time to time, the coat becomes dull, often becomes tangled and does not even correct the situation.

The owners have no idea about the true causes of the condition, attributing it to a seasonal reaction to detergents. Standard measures - a course, increased nutrition, change, etc. do not help.

In some cases, pets develop small areas without hair - above the ears, near the nose, on the elbows. The skin may look completely healthy or have a slight gray tint. It is quite difficult to see such flaws in long hair.

Such processes can occur when the body’s resistance to this type of fungus is insufficient, or the fungus is opportunistic and does not threaten serious consequences. But at any moment, with accompanying factors, it can begin to progress. To find out whether the level of skin fungus is within the normal range, special skin scrapings are taken for analysis.

Diagnosis of fungus in dogs and treatment

First of all, the veterinarian shines a special lamp through the fur, under the rays of which the fungus begins to glow greenish. But you should know that almost half of the mushroom species do not glow. This method does not provide information about the pathogen, but only confirms its presence.

To prescribe effective treatment, a full diagnosis is required, which allows you to determine the type of fungus, the number of spores, and determine sensitivity to certain medications.

Quite often, a fungal infection accompanies allergic manifestations, and treatment gives only a temporary result. An analysis that determines the pet’s allergic status will help here. Identifying the allergen and eliminating it will solve the fungus problem.

A biochemical blood test will allow you to assess the general condition of the animal’s body and find out which organs are failing.

Taking into account all the data obtained, the doctor will be able to prescribe adequate treatment the first time. This will help avoid long-term useless therapy with constant changes of drugs.

For minor skin lesions, ointments are prescribed - Mycozolon, Yam, Clotrimazole, etc. If the fungus affects large areas of the skin, it is not worth using external antifungal drugs externally, since this group of products is toxic. In this case, detergents such as Nizoral and Imaverol are used.

In addition to external medications, veterinarians prescribe medications in tablets or injections. Fluconazole is particularly effective in the treatment of fungi. Help is also provided to the animal’s immune system in the form of immunostimulants and modulators. It is also recommended to take hepatoprotective agents.

If the identified fungus turns out to be contagious, additional measures will need to be taken: carry out the treatment with gloves, and also, if possible, isolate the animal, excluding its contact with children and other pets. But you should visit your dog so that it does not feel lonely or stressed.

Doctors warn that self-treatment can lead to disastrous results. Since some drugs can significantly increase the persistence of the fungus, in this case it will be necessary to treat the fungus in the dog for a longer time.

Prevention of fungal infections

As noted, it is difficult for a fungal pathogen to develop in a healthy, strong body. Therefore, it is important to provide adequate nutrition and appropriate conditions. During this time, you should avoid the habitats of stray animals.

They are characterized by low effectiveness from fungal diseases and in some cases can cause complications, so they are used only in exceptional cases when other therapy is powerless.

But there is no single way to prevent your pet from becoming infected with pathogenic fungi. In this case, it is important to identify the disease as early as possible and seek qualified help.

Dr Tim Nuttall Senior Lecturer in Veterinary Dermatology, University of Liverpool, UK.

Introduction

Many skin conditions require short-term or long-term anti-inflammatory treatment. The most common example is atopic dermatitis (AD). Glucocorticoids are inexpensive, easy to use, and effective, but systemic treatment often results in serious acute and chronic side effects.

Topical glucocorticoids

Local application is a convenient option, since the drug acts directly on the area of ​​inflammation, avoiding general effects. Hydrocortisone-containing drugs: betamethasone, triamcinolone and prednisolone are effective in cases of various inflammatory dermatoses, including atopic dermatitis in dogs. Hydrocortisone is the least potent, prednisolone is more potent, and fluorinated glucocorticoids such as dexamethasone, triamcinolone, betamethasone, and fluocinolone acetonide are the most potent.

The effectiveness of the drug depending on the form of release of the drug and the location of the pathology on the body

Efficiency depends on the form of release of the drug with a large number of occlusive and fat-soluble compounds that increase the absorption and activity of the active substance. The forms of the drugs are presented in order of increasing effectiveness: sprays, gels, lotions, creams and ointments. Sprays, lotions and gels are easy to use, dry quickly and leave no residue. The absence of product residue on the skin helps reduce the likelihood of the product being licked off after application.

Does product absorption depend on the application area?

The most popular drugs are limited to use only on areas without hair. Lotions, gels and especially sprays can penetrate the skin through the fur, which expands the range of application of the drug.

Side effects

Despite the benefits of topical application, long-term treatment may be required for skin atrophy, ulcers, alopecia and comedones. Most glucocorticoids are readily absorbed into the blood, and treatment may result in changes in hypothalamic-pituitary-adrenal (HPA) axis function and iatrogenic hyperadrenocorticism. Symptoms may appear within 2-4 weeks after 5-7 days of use.

Therefore, topical glucocorticoids are not considered to be completely harmless drugs. The risk of side effects increases with the use of more potent glucocorticoids, which should be used with greater caution. Potent drugs can be used in the first stage of treatment to achieve remission, after which it is necessary to switch to less powerful drugs.

Topical glucocorticoids based on diesters

The development of non-halogenated glucocorticoid diesters has been a breakthrough in the treatment of inflammatory skin diseases. These drugs have helped avoid many of the problems associated with the use of topical glucocorticoids due to their low metabolism in the skin. Double esterification significantly improves the penetration of the drug through the stratum corneum and ensures specific metabolism in the deep layers of the skin. This minimizes the impact on hair follicles, skin fibroblasts and blood vessels, reducing the likelihood of side effects.

Topical glucocorticoids based on di-esters in veterinary medicine

Dermatology

A new topical glucocorticoid, hydrocortisone aceponate (Cortavance ®, Virbac, France), has been approved as a 0.0584% spray for the short-term treatment of pyotramatic dermatitis, flea allergy dermatitis and other inflammatory dermatoses in dogs. Clinical trials of this drug have demonstrated high efficiency and safety in the treatment of other inflammatory skin diseases of animals.

Safety

Field trial data submitted for registration of the drug confirmed the safe use of Cortavance in the treatment of large parts of the body (more than 1/3 of the body surface), there were no abnormalities in blood counts, biochemistry or other parameters.

In addition, the product does not cause skin atrophy or changes in the dermal and epidermal structure when applied to healthy skin.

Efficiency

"Cortavance" is very effective in the treatment of centralized inflammatory lesions, such as pyotramatic dermatitis, flea allergic dermatitis and other localized dermatoses.

"Cortavance" spray is designed to penetrate the hair of animals with thick hair, and also allows you to treat large areas of the body.

Conclusion

The appearance of Cortavance is a significant step forward in veterinary dermatology. This is the first topical di-ester glucocorticoid registered for use in veterinary medicine. Its formula is uniquely suitable for solving hair problems and has a wide range of applications. Tests have proven the effectiveness and safety of the drug in the treatment of atopic dermatitis in dogs, purulent-traumatic dermatitis and flea allergic dermatitis. According to practicing veterinarians, Cortavance is also safe and effective in the treatment of various inflammatory dermatoses in dogs, cats and horses. Therefore, "Kortavance", is likely to become a widely used anti-inflammatory drug in veterinary practice.