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Polysorb daily dose for adults. Polysorb - instructions for use, reviews, analogs and forms of release (powder for preparing a suspension of MP, Plus, tablets) of a drug for the treatment of intoxications, cleansing the body and losing weight in adults, children and when taking

Often, in the treatment of diseases and poisonings, it is necessary to use enterosorbents. One of the most effective drugs in this class is Polysorb MP. Despite the fact that the drug has gained well-deserved popularity among doctors and patients, not everyone knows the principle of action of this drug and how to use it.

Pharmacological action

The term “sorbents” in medicine, and not only, refers to substances of different physical states that are capable of absorbing foreign substances from the environment in a gaseous or liquid state.

In medicine, sorbents are most often used to remove toxic substances from the body that are formed during inflammatory processes, or get there as a result of poisoning of various origins.

The main requirements for medical enterosorbents, in addition to high sorption properties:

  • non-toxic,
  • harmless to the mucous membranes of the gastrointestinal tract,
  • ability for good evacuation from the intestines,
  • convenient dosage form.

One of the popular sorbents in modern domestic medicine is Polysorb. This new generation drug has almost all of the above properties. This simple in composition and very effective medicine is widely used in the treatment of various pathologies.

The drug is also found in medical texts under the name Polysorb MP. In fact, Polysorb and Polysorb MP are the same drug. The abbreviation “MP” denotes the area of ​​application of the drug – “medical oral”. It was introduced in order to distinguish the drug from its veterinary variety – Polysorb VP.

The process of sorption or absorption according to the mechanism of implementation is divided into two types: adsorption and absorption. Adsorption refers to the absorption of substances through chemical interaction of the sorbent with them. And absorption is absorption that occurs due to the formation of a solution in a solid or liquid state between the sorbent and the absorbed substance. Polysorb is classified as an adsorbent substance.

Once in the gastrointestinal tract, the drug has an adsorbing effect on toxins of exogenous and endogenous origin, removing them from the body. In addition to toxic substances, Polysorb absorbs in the human body:

  • pathogenic microorganisms;
  • toxins of bacterial origin;
  • allergens of various origins;
  • substances produced in the body during an allergic reaction;
  • poisonous substances;
  • breakdown products of heavy metals;
  • radionuclides;
  • alcohol and its breakdown products.

Polysorb also actively absorbs some metabolic products in the body:

  • bilirubin;
  • urea;
  • cholesterol;
  • lipid complexes;
  • metabolites leading to the development of endogenous toxicosis.

In addition, Polysorb has an enveloping effect and envelops the intestinal walls, protecting them from irritation. In the classification of medical drugs, Polysorb is also classified as an antidiarrheal agent.

The maximum volume of absorption of foreign substances by the drug (sorption capacity) is 300 mg/g, and the specific sorption surface is 300-400 m2/g. At the same time, the characteristics of silicon dioxide do not allow it to dissolve under the influence of aggressive substances in the gastrointestinal tract or decompose into simpler components. Therefore, the drug is excreted unchanged from the body. Polysorb begins its action within a few minutes after administration.

Polysorb MP belongs to the category of non-selective sorbents. This means that it absorbs almost everything that is in the gastrointestinal tract, including medications taken by the patient, beneficial intestinal microflora, nutrients, vitamins and microelements. Therefore, when taking Polysorb, it is necessary to adjust the doses of other medications taken by the patient. Also, in some cases, the doctor may prescribe simultaneous use of probiotics and vitamin-mineral complexes with Polysorb.

Compound

The basis of the sorbent is colloidal silicon dioxide. It is a crystalline, colorless substance with a high degree of strength and hardness. In the preparation, silicon dioxide is presented in the form of a white and light powder, tasteless and odorless. A distinctive characteristic of silicon dioxide is its resistance to acid attack. This property ensures the stability of the compound in the acidic gastric environment. Silicon dioxide is also characterized by the absence of a chemical reaction when interacting with water. If the powder is immersed in water and mixed evenly, a colloidal suspension is formed.

In addition, silicon dioxide is biologically neutral and non-toxic to humans. Silicon dioxide is often used in the food and pharmaceutical industries as an excipient.

The drug does not contain any other components - dyes or flavoring additives, and silicon dioxide itself has hypoallergenic properties. This helps to successfully use the drug in the fight against allergic reactions.

Release form, conditions of release in pharmacies, manufacturer

Polysorb is available in the form of a light white (with a slight bluish tint), odorless and tasteless powder. The powder consists of small particles of silicon dioxide. The drug cannot be used in dry form; for use it is necessary to prepare an aqueous suspension.

The powder can be packaged either in capped plastic bottles or in disposable paper bags. Packages may contain 1, 2, 3, 6, 10, 12 g of the drug, plastic jars - 12, 15, 20, 25, 30, 35, 40, 45, 50 g of the drug.

The drug is produced by the Russian company JSC Polisorb. The medicine can be purchased in pharmacies without a prescription.

Storage conditions for the drug Polysorb MP

The shelf life of the powder is 5 years, it can be stored at a temperature not exceeding +30 °C. If there is unused powder left in the jar, the jar must be tightly closed and moisture should not be allowed to enter. The prepared suspension must be used within 2 days.

Pharmacodynamics and pharmacokinetics

Polysorb MP is a sorbent based on particles of silicon dioxide SiO2 (silica). The particle size is only 0.09 mm. However, the surface of each particle is very large, which allows for a strong adsorbing effect. 1 g of the drug can absorb at least 300 mg of toxins. In this case, the drug is not absorbed into the gastrointestinal tract and is excreted from the body naturally along with feces.

Indications of the drug Polysorb MP

The range of indications for the use of Polysorb is quite wide. It includes almost all diseases, the manifestation or consequence of which is intoxication. Polysorb is most often used for:

  • intoxications of various origins with acute or chronic course;
  • allergies to medications and food;
  • diarrhea;
  • seasonal or chronic allergies;
  • atopic dermatitis, eczema, psoriasis;
  • treatment of hangover syndrome;
  • viral hepatitis, accompanied by increased bilirubin levels, and other forms of jaundice;
  • acute intestinal infections;
  • purulent-septic pathologies (adnexitis, appendicitis, purulent wounds, burns, etc.);
  • dysbacteriosis (as part of complex treatment);
  • chronic renal failure, accompanied by an increased concentration of nitrogenous products (urea, creatinine, uric acid);
  • procedures to cleanse the body of toxins;
  • acute poisoning, regardless of the type of toxic substance.

Externally, Polysorb powder can be used as part of the complex treatment of purulent wounds, trophic ulcers, etc.

In addition, Polysorb is often used as a prophylactic for people who live in regions with unfavorable environmental conditions or work in hazardous industries.

Using the drug for allergies

Polysorb MP is often used in the treatment of allergies. It not only eliminates the symptoms of intolerance to certain substances, but also eliminates the immediate cause of the allergic reaction - allergens that have entered the body. Polysorb is often prescribed for gestosis and toxicosis during pregnancy.

Advantages of enterosorbents in the treatment of allergies:

  • a small number of contraindications,
  • no changes in blood composition,
  • no complications.

Polysorb has an increased ability to absorb protein molecules. This circumstance determines its usefulness in the treatment of allergic diseases. After all, most allergens are protein in nature. Polysorb also:

  • binds excess biological active substances involved in the development of allergic reactions (histamine, serotonin);
  • neutralizes food particles that are not completely digested in the gastrointestinal tract;
  • protects the mucous membranes of the gastrointestinal tract from direct mechanical irritation.

Polysorb has a high speed of action - sorbent particles begin to act within 4 minutes after entering the gastrointestinal tract.

The use of Polysorb for allergic diseases contributes to:

  • increasing cellular and humoral immunity;
  • stabilization of immunoglobulin levels;
  • reducing itching, symptoms of urticaria, swelling.

Use of the drug for poisoning

Symptoms of gastrointestinal poisoning usually include fever, nausea, vomiting, diarrhea, flatulence, abdominal pain, and a feeling of weakness. There is a violation of the water-salt balance, and acute dehydration may develop. Polysorb MP is able to help the patient, regardless of the cause of poisoning. Of course, if toxins have already penetrated the blood, then the medicine will be powerless. However, in most cases, toxins penetrate the bloodstream gradually, remaining in the gastrointestinal tract for a long time. During this period, Polysorb MP is able to neutralize the remains of toxic substances by absorbing them.

Polysorb MP for diarrhea

Diarrhea, or, in common parlance, diarrhea, in most cases is the body’s reaction to the penetration of pathogenic bacteria or viruses into the gastrointestinal tract, as well as to the toxins they release. Such penetration can occur due to poor quality food, failure to comply with personal hygiene rules, etc.

For infectious diseases, the use of enterosorbents is not only a pathogenetic method of treatment, but also an etiological one. This is due to the fact that Polysorb MP directly affects the cause of intestinal infections. It is able to absorb all pathogens and toxins that cause diarrhea. However, we should not forget that Polysorb also promotes the removal of beneficial microflora from the gastrointestinal tract, so taking this sorbent must be alternated with taking probiotics.

Polysorb for weight loss

Some overweight people use enterosorbents to lose weight. Polysorb MP is often used for this. In this case, it is recommended to adhere to the daily dosage of 2 tsp. for 2 weeks. However, it is necessary to remember here that enterosorbents can only be used as one of the components of an integrated approach to this problem. In addition to taking sorbents, it is also necessary to change the diet and increase physical activity. And the constant and uncontrolled use of sorbents can only cause harm, since not only toxins will be removed from the body, but also substances vital for the body.

Instructions for use of the drug Polysorb MP

The drug is prescribed to adults based on a daily dosage of 0.1-0.2 g/kg body weight (6-12 g). It is recommended to take Polysorb MP 3-4 times a day. The duration of treatment is determined based on the severity and type of the disease. For acute intoxications, the duration of the course can be 3-5 days, for chronic intoxications and allergic diseases - 10-14 days. The doctor may also prescribe a second course of treatment after 2-3 weeks.

When determining dosage in children, you can use a table that is based on the patient's weight. Its use is relevant for the normal course of most diseases for which Polysorb is prescribed. The table for dosing the drug looks like this:

For convenience, the volume of the drug is measured with spoons. One teaspoon of the dry substance Polysorb, filled so that the powder protrudes slightly upward, contains approximately one gram of medicine, and a tablespoon filled in a similar way contains three grams. Knowing this ratio, dosing this sorbent is quite simple. The term “approximately” in the dosage of Polysorb should not cause concern. The characteristics of silicon dioxide exclude the possibility of overdose with this medication. However, the maximum permissible dosage, which is 330 mg/kg of body weight, should not be exceeded.

An important factor in the use of this sorbent is the need to use it in dissolved form. Polysorb should not be consumed dry. It is recommended to use ordinary water at room temperature as a solvent. The use of non-carbonated mineral water is allowed. Children can be given the drug dissolved in milk, fruit drinks, juices (without pulp), and compotes.

The drug must be prepared in advance so that the suspension is fresh at the time of administration. It is best to drink the suspension 1 hour before meals.

In addition, the manufacturer of Polysorb provides fairly clear instructions for using the drug for various diseases. This recommendation does not exclude the need for exclusively medical prescription of the sorbent (self-medication is unacceptable), but at the same time it allows you to navigate the intricacies of its use. These instructions for use look like this:

Pathology Dosage of the drug Nuances of use Number of appointments per day Duration of therapy
Allergic reactions to foods Taking the drug should be combined with a meal or Polysorb should be given immediately after a meal. Three times a day. Up to two weeks.
Allergic reactions of a chronic nature or seasonal allergies (recurrent urticaria, hay fever, atopic diseases) The drug is dosed according to the table with the patient’s body weight. Polysorb is taken immediately before meals. Three times a day. Up to two weeks. td>
Acute food or drug allergies Gastric lavage with a 1% solution of Polysorb (10 g/l), then orally in normal dosages. Gastric lavage is performed once. 3 Before the onset of clinical effect.
Atopic dermatitis, allergic bronchial asthma, eczema, psoriasis Polysorb is dosed according to the table with the patient’s body weight. Between meals and medications. 3 Up to 3 weeks.
Acne (pimples) Usually 3 g. It is better to check the exact dosage of Polysorb with a specialist - dermatologist Between meals and medications. It is also possible to treat acne with a face mask made from the drug. 3 Up to 3 weeks
Poisoning of various origins With this diagnosis, Polysorb is prescribed for gastric lavage. To do this, 10-12 grams of powder are diluted in a liter of water and a classic rinse is done. The drug is also prescribed orally at the rate of 0.1-0.15 g/kg body weight 2-3 times a day (for adults). For children, use the dosage table. Washing in case of poisoning is mainly one-time. Three times a day. Up to five days.
Infectious lesions of the gastrointestinal tract Treatment with Polysorb is carried out as part of complex therapy. During the first 5 hours after the start of treatment, Polysorb is taken every hour, starting from the second day - four times a day. 7-10 days.
Viral hepatitis In adults – 0.1-0.2 g/kg, in children – according to the table with the patient’s body weight. 3 times a day. 7-10 days.
Chronic renal failure In adults – 0.1-0.2 g/kg, in children – according to the table with the patient’s body weight. Polysorb is used as an element of complex therapy. Up to 4 times a day. 25-30 days, then a break of 2-3 weeks.
Toxicosis during pregnancy The drug is dosed according to the table with the patient’s body weight. Polysorb is taken before or after meals. The time gap between taking the suspension and food should be at least one hour. Three times a day. Up to two weeks.
Hangover syndrome The drug is dosed according to the table with the patient’s body weight. Immediately after manifestation, five doses of Polysorb are administered at intervals of one hour. In parallel with such therapy, it is necessary to maximize fluid intake. Five times a day. Up to two days.
Preventive therapy for hangover syndrome The drug is dosed according to the table with the patient’s body weight. The dose of Polysorb is used before drinking alcohol, after stopping it and the next morning. Three times per course. Two days.
Preventive therapy for people with harmful living or working conditions The drug is dosed according to the table with the patient’s body weight. Polysorb is taken before or after meals. The time gap between taking the suspension and food should be at least one hour. Three times a day. Up to two weeks.

Polysorb for children

Poisoning, infection with viruses and bacteria, and allergic reactions are much more dangerous for children than for adults. Therefore, the drug is very often used in pediatric practice.

Due to its good tolerability and the absence of toxic components, the drug can be used to treat children, including newborns and infants.

Infants should be given approximately 1 tsp. Polysorb per day. This volume is best divided into 3-4 doses (in the morning, at lunch, at 18-19 in the evening and for the baby).

However, if poisoning occurs, it is best to dissolve 2 tbsp. in a glass of water and give them to the child to drink at one time.

At 2-3 years of age, problems may arise with taking the drug, since the child may refuse to drink the suspension. In this case, it can be added to the child’s favorite dish or drink (juice, jelly, cream soup, compote).

Despite the fact that Polysorb MP is a safe drug, you should consult a doctor before using it in children. This is especially true when it comes to the treatment of allergic reactions.

Advantages of Polysorb over other enterosorbents when used in children:

  • low price,
  • high efficiency,
  • lack of taste and smell,
  • no negative impact on the sensitive mucous membranes of the gastrointestinal tract in children.

Compared with traditional methods of therapy (including taking antiviral and antibacterial agents) for intestinal infections in children, combination therapy using Polysorb and taking etiotropic drugs has the following advantages:

  • faster relief from symptoms of intoxication,
  • more complete destruction of pathogens,
  • reducing the duration of the disease.

Contraindications

There are few situations in which you should not take the drug, and most of them are associated with severe gastrointestinal diseases, the symptoms of which may intensify due to the effects of the drug.

Polysorb is not prescribed for:

  • peptic ulcer of the stomach and duodenum (especially during exacerbations)
  • internal bleeding in the gastrointestinal tract;
  • intestinal atony;
  • individual intolerance to silicon dioxide.

If you are hypersensitive to the active substance, you must stop taking the drug.

Use during pregnancy and breastfeeding

The drug is not absorbed into the systemic circulation and therefore does not have a negative effect on the fetus. For this reason, the drug is approved for use by pregnant women and mothers breastfeeding their children. It is important not to exceed the permissible doses and recommended duration of treatment.

Side effects and overdose

The drug also has few side effects, and the frequency of all of them falls into the “rare” and “very rare” categories. Taking this sorbent may be accompanied by:

  • allergic reactions,
  • constipation,
  • disturbances in the normal functioning of the gastrointestinal tract,
  • intestinal dysbiosis.

To prevent constipation when taking the drug, you should increase the amount of water consumed.

There was no effect of the drug on the speed of psychomotor reactions and the ability to concentrate.

There are no known cases of overdose when using the drug. However, it is not recommended to exceed the maximum permissible dosage of 0.3 g/kg body weight.

In this article we will look at the side effects of Polysorb. This drug is a universal active sorbent with the properties of an antacid medication. This drug binds a variety of pathogenic microorganisms and toxic substances as they pass through the digestive system (stomach and intestines). This product is universal, as it is capable of binding and removing microbial toxins, metabolic products, food allergens, medications, poisons, etc. from the human body.

“Polysorb” is now increasingly prescribed for cleansing the body. At the moment, the pharmacological drug has a large sorption capacity, due to which it can bind several times more harmful substances in comparison with aluminum-magnesium silicates (for example, Smecta), methylsilicic acids (Sorbolong, Enterosgel, Atoxil) ), lignins (“Lignosorb”, “Polyphepan”, “Liferan”) and activated carbon. Taking this into account, the scope of use of this medication is quite wide. Since it effectively relieves intoxication of any nature, it can be used as part of a complex treatment of any pathology, including dermatoses, influenza, allergies, various infections, etc.

Many people are interested in whether Polysorb has side effects, but we’ll talk about that later.

Release form, composition

It is produced in one dosage form - powder for suspension for oral administration. For ease of use, this powder is packaged in plastic jars of 50, 25 and 12 g and double-layer bags of 3 g (single dosage for an adult). Such packaging options help to purchase the optimal volume of the medicine. The product "Polysorb" contains colloidal silicon dioxide as an active (sorbing) chemical element. It contains no other components. Externally, this medication has the appearance of a white powder with a slight bluish tint. The product has no smell. When the powder is dissolved in water, a white suspension is observed. Cleansing with Polysorb should be carried out according to the instructions and recommendations of the doctor.

Therapeutic effect

This product is a group of sorbents of inorganic origin. According to its basic properties, the drug does not have a selective effect, that is, it is able to sorb different classes of substances. Due to such nonspecific activity, as well as increased sorption capacity, the drug "Polysorb" has the following therapeutic properties:

  • sorption;
  • detoxifying.

The detoxifying effect of this medication is due to its main property of binding a wide variety of substances, including toxic ones, and removing them. The basis of detoxification using this product is its sorption effect. The sorbent binds chemicals that entered the body from the outside (exogenous) and were formed directly in it (endogenous). The medicine is able to effectively remove pathogenic microorganisms (viruses, bacteria, fungi), toxins that these pathogenic microorganisms secrete, foreign antigens, medicinal substances, food allergens, poisons, radionuclides, metal salts, ethyl alcohol and its breakdown products. In addition to the above toxic substances, Polysorb binds metabolic products formed in the body. Often, an excess of such products leads to the development of various symptoms of intoxication and pathological processes in the form of diseases.

In addition, Polysorb removes endogenous compounds such as bilirubin, cholesterol, urea, lipid complexes, as well as substances that can cause the development of endotoxicosis. The versatility of the ability to bind toxins allows the use of this medication to eliminate intoxications of almost any etiology - from food poisoning to severe pathological conditions. This sorbent is considered an excellent remedy that is present in combination therapy for many diseases.

The use of this product can significantly reduce the volume of other pharmacological drugs that are necessary for the quality treatment of many diseases. In developed countries, it is considered necessary to use Polysorb even for flu or colds, since this remedy eliminates the unpleasant symptoms of intoxication (muscle pain, apathy, weakness, dizziness).

Indications for use

The list of main indications for the use of the drug "Polysorb" includes the following pathological conditions:

  • intoxication in adults and children in acute or chronic form of any etiology, regardless of the reasons for its development;
  • acute intestinal infections caused by a variety of pathogenic microorganisms;
  • food poisoning;
  • dysbacteriosis;
  • various inflammatory and purulent pathologies that provoke the development of severe intoxications (for example, adnexitis, appendicitis, purulent wounds, burns, etc.);
  • acute poisoning with potent substances and poisons (for example, medications, alcohol, alkaloids, heavy metals, and so on);
  • allergic reaction to food - all types of allergies, in particular hay fever.
  • high concentration of bilirubin against the background of the development of jaundice or viral hepatitis;
  • increased levels of nitrogenous products in the body (creatinine, urea, uric acid) with chronic renal failure;
  • for preventive purposes for people who work in chemical production or live in areas with unfavorable environmental conditions.

In many developed countries, it is customary to use Polysorb for colds. In addition, this sorbent is successfully used in the complex therapy of various dermatological diseases, such as psoriasis, eczema, dermatitis, acne, etc.

We will consider the contraindications and side effects of Polysorb below.

Method of administration and dosage regimen

This pharmacological agent should be taken orally in the form of an aqueous suspension. To prepare it, you need to dissolve the powder in 50-100 ml of water, drink the resulting liquid quickly, without waiting for a suspension to form. Adults take the medication in a volume of 100-200 mg per 1 kg of weight (6 to 12 g of medication). The maximum daily dosage of the medication is no more than 20 g, which must be divided into several doses. "Polysorb" is taken an hour before or after meals. If the sorbent is used to relieve food allergies, it must be taken before or during eating.

The duration of the therapeutic course of this medication is determined by the severity of the pathological process and the speed of stabilization of the patient's condition. For example, when treating acute intoxication (alcohol or food poisoning), it is enough to take the drug for 3-5 days. When treating allergic diseases (dermatitis) or chronic intoxication (for example, renal failure, hepatitis, etc.), a course of treatment lasting 14 days is necessary. In this case, therapy must be repeated every 2-3 weeks. The interval between courses of taking the sorbent cannot be less than 14 days.

Not everyone knows how Polysorb is useful for the body, so we’ll talk about it in the following sections.

The medicine helps with acute poisoning

With this pathology, it is necessary to remove as many toxins and poisons as possible from the body. To do this, you should perform a gastric lavage using a suspension of the drug "Polysorb", after which another 6 g of this drug is taken orally in several doses. The medication should be taken with tea, water or Regidron solution in order to replenish lost fluid. If the poisoning is severe, then gastric lavage must be repeated after 4-7 hours. On the second day of treatment for food infection, the medicine is taken 4 times a day, 3 g and, depending on the patient’s condition, therapy is canceled or extended for another 5 days.

The drug is useful for intestinal infectious diseases

On the first day of development of an intestinal infection, the drug is taken 3 g (tablespoon) every hour. In total you need to use five such dosages. On the second day of therapy, the dose is 3 g 4 times a day. If after such treatment the patient’s condition returns to normal, you can stop taking the medication. If the intoxication cannot be completely removed, the course of therapy with this sorbent is extended for another two days.

Viral hepatitis

A medication as part of combination therapy for hepatitis can reduce the duration of intoxication and the icteric period. It is used at the onset of the disease for 7-10 days, 4 g 3 times a day.

"Polysorb" for cleansing the body

Often this medicine is not used to treat a specific disease, but to cleanse the body in children and adults. This helps to normalize the general condition, complexion, skin structure, and eliminate allergic phenomena.

The use of Polysorb for cleansing should be careful.

Acute allergic reactions

Drug or food allergies begin to be treated with gastric and intestinal lavage with a suspension of this drug. To prepare it, you need to dissolve 10 g of powder in 1 liter of liquid. The intestines are washed with an enema. After the above procedures, the sorbent is taken orally for 5 days, 3 g 4 times a day. For chronic food allergies, longer use of this drug is required - up to 14 days, 3 g four times a day. In this case, the suspension should be drunk immediately before meals. Urticaria, eosinophilia, hay fever, atopic dermatitis and other diseases of an allergic nature are also treated.

Is Polysorb always allowed to cleanse the body?

Contraindications

The drug has some contraindications for use, so before taking the suspension, you need to carefully read the instructions. The list of main contraindications to the drug includes:

  • intestinal atony;
  • drug intolerance;
  • peptic ulcer of the intestines or stomach at the acute stage.

Side effects of the drug

This drug is usually well tolerated by patients and causes virtually no side effects. In extremely rare cases, against the background of the high absorption capacity of the elements present in its composition, the medication can provoke the development of constipation and disruption of the movement of feces through the intestines. In addition, it is very rare that children may develop an allergic reaction to the drug. If you take it correctly according to the instructions, then the risk of side effects from Polysorb will be minimal.

Analogs

Today, the medical product has the following analogues on the Russian pharmacological market:


Sorbents.

Composition of Polysorb

Silicon dioxide colloidal.

Manufacturers

Polysorb (Russia)

Pharmacological action

Polysorb is a new generation sorbent, obtained on the basis of highly dispersed silicon, which has unique sorbing properties that ensure effective and rapid detoxification, both for external and internal use. 1 g of Polysorb structures 15-20 g of water, is capable of binding 300-800 mg of protein, 1x10 or more microbial bodies, protein complexes of bilirubin and bile acids, and normalizes cholesterol levels in the blood.

Neutralizes heat-labile and heat-stable microbial toxins of protein nature.

Adsorption rate (1-4 min.).

Externally, it is a light white powder with a bluish tint, odorless and tasteless.

Unlike drugs of a coal nature, the drug in therapeutic doses does not interfere with the absorption of vitamins and microelements, and does not impair intestinal motility.

Sorbs microorganisms, endogenous and exogenous toxic substances of various natures (including metabolic products, food and other allergens, toxic compounds, etc.) from the gastrointestinal tract.

When used in application, Polysorb has a hemostatic and wound-healing effect, and in the case of purulent-inflammatory processes, it prevents the progression of necrotic changes.

Promotes the rejection of non-viable tissues, ensures active decontamination, detoxification of the lesion and the body as a whole.

Reduces the adhesion of the dressing to the wound, increases the sensitivity of wound microflora to antibiotics, prevents the diffusion of toxins into the tissue, and reduces treatment time.

Removes toxins, radionuclides, heavy metal salts from the body, preventing their adverse effects on the body.

Due to the high purity and homogeneity of Polysorb, its high chemical resistance in the gastrointestinal tract, and the fact that it does not penetrate into the internal environment of the body, both externally and internally, Polysorb and preparations based on it non-toxic.

Side effects of Polysorb

Rarely - allergic reactions, dyspepsia, constipation.

Long-term use (more than 14 days) may impair the absorption of vitamins and calcium, and therefore prophylactic use of multivitamin preparations and calcium is recommended.

Indications for use

Acute and chronic intoxications of various origins in adults and children.

Acute intestinal infections of any origin, including food poisoning, as well as diarrheal syndrome of non-infectious origin, dysbacteriosis (as part of complex therapy).

Purulent-septic diseases accompanied by severe intoxication.

Acute poisoning with potent and toxic substances, including drugs and alcohol, alkaloids, salts of heavy metals, etc.

Food and drug allergies.

Hyperbilirubinemia (viral hepatitis and other jaundices) and hyperazotemia (chronic renal failure).

Residents of environmentally unfavorable regions and workers of hazardous industries for the purpose of prevention.

Contraindications Polysorb

Peptic ulcer of the stomach and duodenum in the acute phase.

Bleeding from the gastrointestinal tract.

Intestinal atony.

Individual intolerance to the drug.

Directions for use and dosage

Take orally only in the form of an aqueous suspension.

To obtain a suspension, thoroughly mix the required amount of the drug in 1/4 - 1/2 cup of water.

The average daily dose in adults is 100-200 mg/kg body weight (6-12 g).

The drug is taken in 3-4 doses during the day.

The maximum daily dose in adults is 330 mg/kg body weight (20 g).

The dose for children is calculated depending on body weight. 1 teaspoon contains 1 g of the drug, 1 tablespoon contains 2.5-3 g.

In cases of food allergies, the drug is taken immediately before meals, the daily dose is divided into three doses throughout the day.

The duration of treatment depends on the diagnosis and severity of the disease; the course of treatment for acute intoxication is 3-5 days; for allergic diseases, chronic intoxications, the duration of treatment is up to 10-14 days.

Features of the use of the drug for various diseases. 1.

Foodborne illness and acute poisoning.

In case of severe poisoning on the first day, gastric lavage is carried out through a tube every 4-6 hours, and the drug is also given orally.

A single dose in adults can be 100-150 mg/kg of the patient’s body weight 2-3 times a day. 2.

On the first day, the daily dose is given over 5 hours with intervals between doses of 1 hour.

On the 2nd day, the daily dose is given in 4 doses throughout the day.

Duration of treatment is 3-5 days. 3.

Treatment of viral hepatitis.

In complex therapy of viral hepatitis, the drug is used as a detoxifying agent in normal doses during the first 7-10 days of illness. 4.

Allergic diseases.

In case of acute allergic reactions of drug or food origin, preliminary lavage of the stomach and intestines with a 0.5-1% suspension of the drug is recommended.

The drug is then given in usual doses until clinical effect occurs.

Similar courses are indicated for acute recurrent urticaria and Quincke's edema, eosinophilia, on the eve of exacerbation of hay fever and other atopies. 5.

Chronic renal failure.

Treatment courses are used in a daily dose of 150-200 mg/kg body for 25-30 days with a break of 2-3 weeks.

Overdose

No data available.

Interaction

Polysorb reduces the effect of other medications taken at the same time.

Special instructions

Polysorb can be used both in monotherapy and in combination with other drugs.

In the latter case, it does not absorb these drugs, but prolongs and enhances their effect.

Polysorb does not have a damaging effect on the skin, gastrointestinal mucosa, internal organs, and does not disrupt the functions of the respiratory, cardiovascular, urinary, endocrine and nervous systems.

Long-term (up to 6 months) intragastric administration of Polysorb does not affect metabolic rates, hematological parameters, or immunological status.

The drug does not have embryotoxic or teratogenic effects.

Storage conditions

Store at room temperature out of the reach of children.

The prepared suspension is stored for 2 days.

Enterosorbent

Active ingredient

Silicon dioxide colloidal

Release form, composition and packaging

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Single use package.
Disposable package (10) - cardboard pack.

◊ Powder for suspension for oral administration; light, amorphous, white or white with a bluish tint, odorless; When shaken with water it forms a suspension.

Polymer cans.

Pharmacological action

Polysorb MP is an inorganic non-selective polyfunctional enterosorbent based on highly dispersed silica with particle sizes up to 0.09 mm and the chemical formula SiO 2.

Polysorb MP has pronounced sorption and detoxification properties.

In the lumen of the gastrointestinal tract, the drug binds and removes from the body endogenous and exogenous toxic substances of various natures, including pathogenic bacteria and bacterial toxins, antigens, foods, drugs and poisons, salts of heavy metals, radionuclides, alcohol. Polysorb MP also sorbs some metabolic products of the body, incl. excess bilirubin, urea, cholesterol and lipid complexes, as well as metabolites responsible for the development of endogenous toxicosis.

Pharmacokinetics

After taking the drug Polysorb MP orally, the active substance is not broken down and is not absorbed into the gastrointestinal tract. It is excreted from the body unchanged.

Indications

  • acute and chronic intoxication of various etiologies in children and adults;
  • acute intestinal infections of various etiologies, including food poisoning, as well as diarrheal syndrome of non-infectious origin (as part of complex therapy);
  • purulent-septic diseases accompanied by severe intoxication;
  • acute poisoning with potent and toxic substances, incl. medications and alcohol, alkaloids, salts of heavy metals;
  • food and drug allergies;
  • hyperbilirubinemia (viral hepatitis and other jaundices) and hyperazotemia (chronic);
  • residents of environmentally unfavorable regions and workers of hazardous industries for the purpose of prevention.

Contraindications

Dosage

Polysorb MP is taken orally only in the form of an aqueous suspension. To obtain a suspension, the required amount of the drug is thoroughly mixed in 1/4-1/2 cup of water. It is recommended to prepare a fresh suspension before each dose of the drug and drink it 1 hour before meals or taking other medications.

For adults the drug Polysorb MP is prescribed in an average daily dose of 0.1-0.2 g/kg body weight (6-12 g). Frequency of administration - 3-4 times/day. The maximum daily dose for adults is 0.33 g/kg body weight (20 g).

A single dose of Polysorb MP for children depends on body weight (see table).

Daily dose = single dose × 3 times a day.

1 heaped teaspoon - 1 g of the drug.

1 heaped tablespoon - 2.5-3 g of the drug.

At food allergies the drug should be taken immediately before meals. The daily dose is divided into 3 doses during the day.

The duration of treatment depends on the diagnosis and severity of the disease. Course of treatment for acute intoxications is 3-5 days; at allergic diseases and chronic intoxications- up to 10-14 days. After 2-3 weeks, the course of treatment can be repeated.

Features of the use of the drug Polysorb MP for various diseases and conditions

At food poisoning and acute poisoning It is recommended to start therapy with gastric lavage with a 0.5-1% suspension of the drug Polysorb MP. In case of severe poisoning on the first day, gastric lavage is carried out through a tube every 4-6 hours, and the drug is also given orally. Single dose for adults is 0.1-0.15 g/kg of the patient’s body weight 2-3 times/day.

At acute intestinal infections Treatment with Polysorb MP is recommended to begin in the first hours or days of the disease as part of complex therapy. On the first day, the daily dose of the drug is taken over 5 hours with an interval of 1 hour between doses. On the second day, the frequency of dosing is 4 times a day. Duration of treatment is 3-5 days.

At treatment of viral hepatitis Polysorb MP is used as a detoxifying agent in an average daily dose during the first 7-10 days of illness.

At acute allergic reactions(medicinal or food), preliminary lavage of the stomach and intestines with a 0.5-1% suspension of the drug Polysorb MP is recommended. Next, the drug is prescribed in usual doses until the onset of clinical effect.

At chronic food allergies They recommend courses of therapy with Polysorb MP lasting 7-10-15 days. The drug is taken immediately before meals. Similar courses are prescribed for acute recurrent urticaria, Quincke's edema, eosinophilia, hay fever and other atopic diseases.

At chronic renal failure use courses of treatment with Polysorb MP at a dose of 0.1-0.2 g/kg/day for 25-30 days with a break of 2-3 weeks.

Side effects

Rarely: allergic reactions, constipation.

Overdose

Currently, there is no data on an overdose of the drug Polysorb MP.

Drug interactions

When using the drug Polysorb MP simultaneously with other drugs, the therapeutic effect of the latter may be reduced.

Polysorb refers to sorbents with a high level of activity. It is able to neutralize microbes and toxic products released by them in the cavity of the gastrointestinal tract, and eliminate toxicosis. A special property of the drug is its effect of neutralizing the acidic contents in the stomach.

Due to its powerful sorption properties, which are much higher than those of other medications of this class, Polysorb is used in more severe cases of diseases with the manifestation of severe toxicosis as part of complex therapy. The drug has a positive effect on a woman’s body during pregnancy, preventing the development of toxicosis.

Composition and release form


Polysorb is available in powder form for the preparation of a suspension that the patient must drink. The powder is packaged in plastic jars with quantities of 12, 25, 50 g. There is a disposable form in the form of a 3-gram sachet.

Along with the main active ingredient (sorbent that reduces toxicosis), the product contains silicon dioxide in colloidal form. This is a medicinal powder of a white-bluish color, without other impurities and odor. Combining it with water gives a uniform white suspension.

Storage conditions

The powdered drug Polysorb should be stored at a temperature not exceeding 45 degrees Celsius for 5 years, and the prepared suspension - within 15 degrees for no more than 48 hours (2 days).

Sold without a prescription. Only a doctor should prescribe it.

Pharmacological action

The drug Polysorb is capable of binding almost all poisonous compounds and toxic substances, as well as neutralizing both poisons coming from outside and waste products of viruses and bacteria formed in the body. This quality of the drug eliminates the symptoms of toxicosis. The medicine softens allergic reactions, eliminates nausea and vomiting. By absorbing these substances in its composition, the drug helps remove them from the body.

Polysorb is capable of removing living forms of pathogenic flora, bacterial cells, fungal pathogens and even viruses.

The product neutralizes drugs, radionuclides and heavy metal salts well.

A strong effect was noted when neutralizing the products of alcohol catabolism (acetaldehydes).


The drug Polysorb helps the body get rid of excess of its own metabolic and breakdown products that provoke toxicosis. Therefore, it can be used for almost any pathology that causes intoxication. Bilirubin binds well and is excreted in pathologies of the liver and gallbladder. Cholesterol compounds, all types of lipids and other biological compounds are perfectly neutralized.

Polysorb is included in therapeutic regimens for the treatment of a significant number of pathologies. Its powerful action allows you to limit yourself to a minimum set of drugs used.

The medicine can also be used for infectious diseases with toxicosis, especially influenza and respiratory viral infections. Taking it when prescribed by a doctor relieves the patient of the need to use antipyretic drugs, accelerates the regeneration of the body and the healing process.

Indications for use of Polysorb

Polysorb is most effective as part of complex therapy for the following problems:

  • any types of toxicosis caused by infectious diseases, especially those occurring with primary damage to the intestinal tract, nausea, vomiting, diarrhea - food poisoning (toxic infections), salmonellosis, dysentery;
  • inflammatory processes and the consequences of injuries in the body, especially in the purulent stage with severe intoxication - burn disease, frostbite, wounds with purulent contents. Effective for purulent complications after severe abdominal surgical operations on the gastrointestinal tract, chest cavity, and gynecological problems;
  • acute alcoholic and, especially, metal alcohol toxicosis, drug intoxication and complications caused by poisoning with medicinal substances and industrial toxins;
  • diseases of the hepatobiliary and renal systems with liver and kidney failure, which cause severe poisoning of the body with toxic substances of an endogenous nature - bilirubin, uric acid, nitrogenous compounds;
  • during pregnancy with toxicosis;
  • skin diseases, manifested by cracks, rashes, pimples.

Polysorb is able to alleviate the condition of allergic reactions and viral diseases. Effective for food allergies.

Contraindications for Polysorb

In some cases, there are restrictions and contraindications to the use of the drug Polysorb, for example, in case of difficulty in swallowing.

Take the drug carefully when:

  • complications of gastric ulcer and duodenal ulcer - penetration (transition of the ulcerative process to nearby organs), perforation, bleeding, degeneration into a tumor process;
  • violation of the evacuation function of the intestines, accompanied by constipation, severe bloating, pain caused by distension of the intestines with feces and gases;
  • individual intolerance to the drug;
  • severe nausea and vomiting.

Side effects of Polysorb

In some cases, side effects of Polysorb are observed:

  • impaired intestinal motility, accompanied by constipation;
  • hypersensitivity reactions to the drug (allergic manifestations);
  • intolerance to the drug substance and components;
  • dyspeptic symptoms - belching, unpleasant aftertaste, feeling of fullness in the abdomen.

Polysorb: instructions for use

The medicinal form of the drug is a suspension. It is prepared before use by stirring the contents of the sachet with water. For one-time use, 50-100 ml of water is enough. The resulting medicinal composition should be taken half an hour before meals or tablets. For allergic processes, especially those caused by food allergens, the medicine should be taken during or immediately before meals.

The main daily dose is divided into several doses (usually 3-4). For adults, the amount of the drug is calculated based on body weight. 100-200 mg of powder should be used per 1 kilogram.

The maximum daily dose used is 20 g. In some cases, with large body weight, it is allowed to use 25 g of Polysorb during the day.

The drug should be discontinued immediately after the manifestations of toxicosis decrease. A course of treatment of up to 14-20 days is allowed. Then you definitely need to take a break for at least 2 weeks. Courses of treatment can be repeated for chronic processes, exacerbations and as prescribed by a doctor.

The exact doses, frequency of administration and duration of use of the medicine should be discussed with your doctor, avoiding independent decisions.

Special instructions for use and warnings

Long-term use of Polysorb can lead to a deficiency of beneficial nutrients - proteins and vitamins, as well as calcium. Therefore, while using the drug, you should pay attention to a varied diet and additional intake of vitamin and calcium complexes.

Overdose

Cases of drug overdose are unknown and have not been described anywhere. If for some reason the drug was consumed in excess, then it is enough to simply create a more intense water regime, which will independently remove the excess drug while maintaining the normal therapeutic effect. You should definitely report the problem to your doctor.

Interaction with other drugs


Please note that the simultaneous use of Polysorb with other medications can significantly reduce or eliminate their therapeutic effect.

Interaction with alcohol

The use of Polysorb before and during alcohol intake promotes its faster elimination - removal from the body naturally. In case of acute alcohol toxicosis, the drug removes toxic breakdown products of ethyl alcohol. In chronic alcoholism, it is part of long-term treatment to eliminate the consequences of alcoholism.

Polysorb for children

In pediatric practice, the use of Polysorb is a common method of therapy, especially in the complex treatment of childhood diathesis, toxicosis and allergies, renal failure, rashes, and acne.

Features of the application is the dosage depending on the weight of the child. For convenience, doctors prescribe the medicine, dosing it in teaspoons and tablespoons. It is conventionally noted that a teaspoon of powder corresponds to 1 g of medication, and a tablespoon corresponds to 3 g.

A suspension is prepared from the powder, for which the drug is dissolved in 50-100 ml of water. The suspension must be drunk immediately after preparation.

Children weighing up to 10 kg should take a daily dose of Polysorb 0.5 - 1.5 teaspoons of powder. When the weight of a small patient is from 10 to 20 kg, the dose can be increased three times - drink 3 teaspoons per day.

A child up to 30 kg is given 3 teaspoons (heaped) per day.

With a weight of 30 to 40 kg, the dose is increased to 2 teaspoons per dose (3 times a day).

Weight more than 40 kg allows you to take Polysorb using a tablespoon three times a day. Sometimes a sorbent suspension can be prepared 4 times a day.

Upon reaching a body weight of 60 kg, a single dose can be 2 tablespoons of powder to prepare a suspension. Daily dose – 6 spoons.

The duration of the course of treatment is up to 2 weeks (14 days).

Polysorb during pregnancy

It is recommended to take Polysorb during pregnancy for the same reasons as in normal cases in adults. The peculiarity of using Polysorb during pregnancy is that it is recommended for the prevention and treatment of pregnancy toxicosis and reduces nausea.

Polisorb's analogues


Russian-made analogues of Polysorb, sorbents with other active ingredients that reduce toxicosis, include the following drugs:

  • Microcel; Smecta, Enterumin, Diosmectite (in powder form for suspension);
  • Enterodesis (in powder form for solution);
  • Lactofiltrum, Entegnin (tablets);
  • Enterosgel (produced in the form of a paste or gel from which a solution is prepared);
  • Lignosorb (granules and paste).

It should be noted that their similar effect in eliminating toxicosis is less pronounced than that of the drug Polysorb.