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Vitamin B6 instructions for use, injections. What is Vitamin B6 (pyridoxine) for?

Vitamin B6 is a water-soluble element that is important for the health of adults and children. With the help of this component, the process of assimilation of unsaturated fatty acids, which are necessary for cellular synthesis, occurs.

Pyridoxine, through active interaction with calcium, supports heart function. It is also involved in hematopoiesis.

A deficiency of this microelement in children causes disturbances in the functioning of the nervous system. The baby begins to be capricious, sleeps restlessly, and sometimes muscle spasms may even appear. However, only the attending physician will prescribe the drug for a child under 1 year of age.

Need for admission

All B vitamins are important for the normalization of many biochemical processes in the human body. In addition, they help improve visual acuity and also have a beneficial effect on the condition of the skin.

Pyridoxine helps the liver function properly. It also affects the following body processes:

  • normalizes the functioning of the nervous system;
  • controls blood glucose levels;
  • helps carry out energy metabolism in the body;
  • increases the production of serotonin, a hormone that is responsible for happiness;
  • improves the body's protective functions;
  • has a beneficial effect on appearance.

Pyridoxine deficiency occurs extremely rarely in an adult. This is because this component enters the body daily with the food we eat. Since the children's body is subject to the negative influence of the environment, some children may have a deficiency of one or another element.

A deficiency of this vitamin causes the following symptoms:

  • mood variability;
  • apathy and lethargy;
  • lack of healthy sleep;
  • the skin takes on an uncharacteristic yellow color;
  • disruptions in the functioning of the cardiovascular system.

The dosage of the drug for infants under six months of age should not exceed 500 mcg per day. If necessary, as the child grows, the maximum dose increases. Thus, already at the age of 1 year, 1 mg of the substance per day is allowed.

IMPORTANT! A deficiency of this component is often observed in young children who are bottle-fed with formula.

Indications for use for children

The main reason why Vitamin B6 is used and why children need it is vitamin deficiency in various forms. The disease provokes the following manifestations in the baby:

  • numerous dermatitis on the face and neck;
  • cracks on the lips;
  • sores in the mouth;
  • eye inflammation;
  • poor appetite;
  • nausea and vomiting.

However, if any symptom appears, you should not immediately start taking pyridoxine. Because such signs are characteristic of many other abnormalities that occur in children. Only a doctor can prescribe the drug and calculate the dosage, especially when it concerns the baby’s health.

Also vitaminB6 are used for the following deviations:

  • Anemia. The component promotes the production of hemoglobin and is involved in the process of hematopoiesis.
  • Hepatitis of various forms.
  • Neurological abnormalities.
  • Diabetes. The trace element helps normalize glucose levels.
  • Autism in a child.

In this case, it is important to remember that Pyridoxine is only an auxiliary substance that will help speed up the treatment process for the above pathologies. However, you should not hope that only with the help of vitamin complexes you can get rid of the symptoms of anemia, diabetes and other diseases.

Instructions for use

Instructions for using the drug for treating a child are practically no different from those recommended for adults. The main difference in administration is the correct dosage of the component.

For preventive purposes, children over 6 years of age are recommended to take no more than 2 mg of the drug per day. If the drug is used in the treatment of any disease, then a dosage of up to 20 mg per day is acceptable. However, this depends on the age of the child.

When muscle spasms occur in children, injections of the drug become necessary. Pyridoxine is administered intramuscularly or intravenously up to 100 mg per day.

There is still no dose of the drug that could be considered the maximum. The required amount of the substance is calculated based on the characteristics of the patient’s body and the severity of the disease.

Overdose and side effects

The drug does not cause toxic effects, so overdose is extremely rare even after taking the substance above the norm specified in the instructions. However, sometimes undesirable symptoms occur when consuming a large dose of a substance:

  • rash on the skin;
  • stitching sensation on fingertips;
  • loss of consciousness.

If such symptoms occur, you should stop taking this drug. Already 1-2 days after stopping therapy, the condition will return to normal. If after a while the signs of an overdose continue to bother you, then the child needs urgent medical attention.

Interaction with other drugs

Substances that reduce the level of vitamin activity:

  • when pyridoxine is used with certain types of antibiotics, the effectiveness decreases;
  • when the component is combined with vitamin C and nicotinic acid, its effect is also reduced;
  • Some types of antidepressants can reduce the concentration of vitamin B6 in the blood.

But certain types of beneficial components contribute to the enhanced effects of pyridoxine. Thus, when taking the drug in combination with glutamic acid, vitamin B6 enhances its effect.

Vitamin B6 is often prescribed to be taken in combination with magnesium. Then it only acts as a catalyst for better absorption of magnesium.

Where is it contained?

It is found in foods of plant origin: buckwheat, beans, lettuce, green onions, rolled oats. The component is also found in lower concentrations in: dairy products, chicken, and fish.

The vitamin loses most of its beneficial properties after heat treatment. Especially if the dish was cooked under a closed lid. Also, such products become less useful after prolonged freezing.

If a child is prescribed to take Pyridoxine, then the daily dose should be divided into 2 or 3 doses. Also, you should not take the drug with milk or use it in combination with calcium.

In 1934, the American scientist Paul Györdi discovered a new vitamin classified as group B. It was called pyridoxine hydrochloride. This is vitamin B6. Four years later, through hard work and numerous experiments, the chemist isolated a water-soluble crystalline compound.

In fact, this vitamin can be divided into three components, which are called pyridoxine, pyridoxinal, pyridoxamine. They closely interact with each other, playing an important role in the formation of blood components - red cells and antibodies.

Vitamin B6 belongs to coenzymes - substances necessary in the metabolic process that cannot accumulate in cells and are regularly excreted from the body.

Physical and chemical properties

Vitamin pyridoxine deteriorates from long-term storage. It decomposes in light, dissolves and loses its properties in water and alcohol. During food heat treatment of products containing the compound, its partial decomposition occurs. Another category of substances that harm the integrity of the vitamin are estrogen hormones.

Peculiarities

Despite the fact that pyridoxine is a component of many plant products, it cannot be completely absorbed. This is why, according to scientists’ statistics, 20% of the Earth’s inhabitants have a deficiency of the chemical compound and related problems.

The absorption of the vitamin is optimized in tandem with thiamine. There is also an opinion among scientists that the effect of B6 is enhanced if foods containing potassium and magnesium are present in the diet.

The vitamin is produced in small doses by a special beneficial bacterium that lives in the intestines. However, this is not enough for the normal functioning of the body, and healthy microflora, unfortunately, is observed in a small number of people today.

Treatment with antibiotics, taking antidepressants and bad habits destroy this chemical compound, preventing it from being produced in sufficient quantities and doing its job.

Since B6 cannot accumulate, and its remainder is excreted daily in the urine, it is simply impossible to get an overdose by consuming it naturally from natural products.

Daily norm

An adult should receive approximately 2.5 mg of the vitamin per day, a child under 14-15 years old should receive from half to one milligram. The norm for a teenager is 1-2 milligrams, and for an expectant mother – 5 milligrams.

Valuable qualities

How is vitamin B6 useful, why include foods containing it in your diet? There are many answers to this question: this chemical compound is involved in a number of processes and has a whole range of useful functions.

  • A normal amount of pyridoxine helps fight malignant tumors. As is known, they are tumors that appear from uncontrolled cell division of a particular organ. By binding free radicals, pyridoxine hydrochloride prevents this process, reduces its risk and stimulates the body's own defense mechanisms to fight.
  • A number of properties make this chemical compound indispensable for women's health. Vitamin B6 regulates hormone levels, eliminates imbalances, promotes conception and normal pregnancy. An interesting property is that it has some effect on the effect of contraceptive drugs - it may decrease.
  • Regular intake of pyridoxine improves the appearance of skin and hair, helps eliminate dandruff, and prevents early aging of the epidermis. Scientists have established an effect on the processes of collagen formation - they are normalized, and the skin becomes more elastic. Due to these properties, B6 can be called the beauty vitamin.
  • Pyridoxine hydrochloride is directly involved in metabolic processes. It promotes the absorption of proteins, breaks down fats and helps them digest. Metabolic processes accelerate, the body begins to remove toxins more intensively, which affects both the appearance and the general state of human health.
  • The absence of this vitamin can cause kidney stones. The reason for this is the combination of calcium oxalates and oxalic acid, which contributes to the disease.
  • The most important function of B6 is its participation in the synthesis of the hormone serotonin, which improves mood and causes a feeling of joy.
  • The normal content of pyridoxine makes it possible to travel with pleasure for those who could not do so due to motion sickness. The substance reduces nausea during seasickness, in a car and on an airplane.
  • This vitamin promotes the production of amino acids - cell builders, essential substances for strong and healthy muscles. Therefore, pyridoxine can be called an important component of the diet of athletes and those people who monitor their physical fitness.
  • The presence of B6 determines the formation of a normal number of red blood cells in the blood.
  • With the regular intake of this chemical compound into the body, the water-electrolyte balance is normalized and the required amount of salts is maintained in the cells.
  • The vitamin has a direct effect on the transmission of nerve impulses and alleviates the condition of patients with problems of the central nervous system.
  • Together with thiamine, pyridoxine reduces the likelihood of heart attacks or strokes. This is facilitated by a reduction in the number of cholesterol plaques that appear due to poor nutrition and addiction to bad human habits.

B6 and weight loss

As you know, in order to get rid of extra pounds, it is important to eat right and include feasible but regular physical activity in your daily routine.

However, another important point in weight loss technology is the intensive breakdown of fat. The role of pyridoxine in this is difficult to overestimate.

By accelerating metabolic processes, it helps to bring the figure to the ideal. But there is one condition: regular inclusion of foods containing B6 in the diet for several months. This will give a real effect, otherwise you won’t be able to lose weight quickly.

Pyridoxine and pregnancy

By increasing the quality of nerve impulses, the chemical compound contributes to the normal and successful formation of the brain and central nervous system of the fetus. B6 also reduces the risk of uterine tone, early labor, and facilitates the recovery process after cesarean section. By increasing the intensity of the removal of toxic substances, pyridoxine somehow alleviates the serious condition of early toxicosis.

Indications for use

  • diabetes mellitus;
  • dysfunction of the pancreas;
  • hypertension;
  • nausea after eating, indigestion;
  • night cramps;
  • general weakness and dizziness;
  • iron deficiency in the body;
  • bad mood and depression;
  • insomnia;
  • loss of appetite;
  • dermatological diseases;
  • weakened immunity and frequent colds.

Pyridoxine deficiency can also occur in infants. In this case, there is excitability, frequent crying and poor sleep, convulsions, growth retardation, stomach and intestinal disorders.

What should you eat?

Pyridoxine is a vitamin found in various plant foods.

If you include them in your diet daily, the chemical compound will improve your metabolism and eliminate health-related problems.

Which vegetables, fruits and grains supply the body with vitamins and can safely be called rich in pyridoxine?

  • Whole wheat bread. The presence of B6 is due to the content of the yeast in which it is included, and the grain itself. It should be remembered that the portion should be small, since bread is a fairly high-calorie product. You can combine it with vegetables.
  • Cereals. Almost all cereals include this vitamin.
  • Wheat bran, as well as wheat ovary, are a source of B6.
  • Melon. It is important to remember that the fruit is valuable in its season. Melons brought to the northern region in the middle of winter are unlikely to be healthy.
  • All types of cabbage. White and red cabbage, cauliflower and kohlrabi, broccoli and Brussels sprouts are rich in pyridoxine. If possible, cabbage should be consumed raw, in salads. If you cook this vegetable, it is best to steam it, bringing it to the “al dente” state, that is, “to the tooth.” Let the cabbage be a little crispy.
  • Asparagus. It is recommended to cook it in the same way as cabbage.
  • Garlic. It is especially useful in its raw form, but if you have gastritis, ulcers or problems with the pancreas, you should be very careful and observe moderation.
  • Potato. It is best to bake the tubers or boil them in their skins: this way more nutrients are retained inside. Young potatoes are healthy to eat with their skins on.
  • Legumes. Peas, beans, and lentils, rich in vegetable protein, help reduce B6 deficiency in the body. You can cook soups and main courses with them, and, for example, even healthy desserts are made from chickpeas.

Modern people, especially those living in the city, experience an acute shortage of fresh, clean air, physical activity, and healthy food. His nervous system is constantly under stress and is in tension. Overload at work or study, a large amount of time spent at the computer and in front of the TV - all this affects the general condition, the absorption of nutrients, and metabolism. Regular consumption of foods containing pyridoxine will help the body function as nature intended.

One ampoule of injection solution contains the active ingredient: pyridoxine hydrochloride 10 or 50 mg.

Additional substance: water for injection.

The tablet contains 2, 5 or 10 mg pyridoxine hydrochloride.

Release form

Pyridoxine hydrochloride in the form of a solution for injection, packaged in ampoules of 1 ml, 10 ampoules per box.

The tablets are packaged in a jar of 50 pieces.

Pharmacological action

The drug has an effect replenishing the deficit .

Pharmacodynamics and pharmacokinetics

As is known, vitamin B6 is an indispensable participant in metabolic processes, normalizes and supports the activity of the nervous system. The phosphorylated form of pyridoxine is a significant number of coenzymes that affect non-oxidative amino acid metabolism, such as decarboxylation or transamination. This component is necessary for metabolic processes, , glutamine , methionine and other amino acids. It is also important for exchange histamine, and to normalize lipid metabolism.

Analogues of the drug are: , Pyridobene, Pyradoxin, Adermin, Becilan, Pirivitol, Bedoxin, Benadon, Hexabetalin, Hexabion, Hexavibeks and others.

Combination + is a fat-soluble analogue of vitamin B1 or. This combination normalizes the functions of the nervous system, taking part in carbohydrate metabolism, replenishing the deficiency of vitamin B1.

Alcohol

Excessive alcohol consumption reduces absorption vitamin B6 , increasing the body’s need for it.

Pyridoxine for hair

Vitamin masks prepared at home are very popular. Pyridoxine for hair is often used for this purpose. It is known that this substance has a positive effect on hair growth and normalizes blood circulation.

To make a mask for medium length hair, use Pyridoxine-Vial in ampoules - approximately 4-5 pieces.

You need to mix a spoonful of castor, olive and burdock oils. Heat this mixture in a water bath, add the solution Pyridoxine-Vial and any other essential oils that suit your hair type. Mix everything well and apply to hair. You can put on a cap and wait for 30-40 minutes. Then wash your hair and rinse well with cool water. Practice shows that such a product makes hair not only shiny and silky, but healthy and strong.

Reviews about Pyridoxine

Medical websites and forums in most cases contain positive reviews about Pyridoxine. This drug is prescribed to many patients in the complex treatment of a variety of disorders, for example: hypovitaminosis B6, leukopenia, herpes zoster, and so on. Almost always, this vitamin significantly accelerates the healing effect.

However, some users ask: Pyridoxine – what is it? And when they find out that this is the name of vitamin B6, they are very surprised. As you know, Pyridoxine helps well with toxicosis in pregnant women, eliminates the symptoms of air and sea sickness. But not many people know that this substance is used in combination therapy for diseases of the central nervous system.

It should be noted that patients often use not the drug in ampoules, but its tablet form.

Among the many positive reviews, there are reports of the development of negative effects. In some patients, while taking this medicine, the acidity of the gastric contents increased, causing severe pain in patients with gastritis. However, experts say that compliance with the dosage and taking into account contraindications - ulcers and stomach diseases, will not lead to the development of side effects, since the drug is well tolerated. In rare cases, allergic reactions develop, but, as a rule, all symptoms disappear after discontinuation of the drug.

Pyridoxine price, where to buy

For Pyridoxine tablets, the price varies between 40-60 rubles.

The price of Pyridoxine in ampoules is 20-35 rubles.

  • Online pharmacies in Russia Russia
  • Online pharmacies in Ukraine Ukraine
  • Online pharmacies in Kazakhstan Kazakhstan

ZdravCity

    Pyridoxine (Vit B6) tab. 10mg n50 Ozone LLC

    Pyridoxine (Vit B6) solution d/in. 5% 1ml No. 10 Borisov plantBorisov plant

Pharmacy Dialog

    Vitamin B6 (pyridoxine h/x) (amp. 5% 1ml No. 10)

According to scientists, which is based on their numerous studies, modern man does not receive the required amount of nutrients (vitamins, minerals). We usually get these substances from food. But few modern people follow the principles of a healthy, balanced diet, preferring snacks, semi-finished products and mono-diets. Hence the emergence of a deficiency of vitamins, minerals, and other essential substances.

Very often the body lacks vitamin B6. It is one of the vital elements needed for health. Its daily requirement is 2.0 mg per day and no less. Vitamin B6 is involved in the synthesis of serotonin, known as the hormone of happiness. Therefore, it is often called an antidepressant vitamin. If there is the required amount of B6 in the blood, a person does not lose peace of mind, he often experiences joyful emotions, being in a good psycho-emotional state.

With its deficiency, a person suffers from insomnia, dermatitis develops on the skin, and attacks of irritability occur more and more often. Also, deficiency of this substance has a negative effect on the liver.

Any modern pharmacy offers vitamin ampoules with vitamin B6 or tablets. Each package contains instructions for this drug. But you can take additional vitamin B6 only as prescribed by a doctor, after an appropriate medical examination. Remember that an excess of it is no less dangerous than a deficiency. But treating the consequences of such an excess is much more difficult.

What are the indications for use of the vitamin B6 drug?

First of all, the drug is prescribed in the presence of hypo- and vitamin deficiency of this particular substance. This often happens with various diets and poor nutrition. The remedy is also indicated in the treatment of long-term infectious diseases.

The drug is effective for diarrhea, enteritis, malabsorption syndrome. It is prescribed for stressful conditions, as well as conditions after resection of the stomach and intestines. Recommended during hemodialysis.

The vitamin is prescribed as part of complex therapy for hypochromic or microcytic anemia. Included in the treatment of Parkinson's disease, radiculitis, Little's disease, neuritis and neuralgia.

Used in the treatment of congenital pyridoxine-dependent convulsive syndrome, sometimes observed in newborns. Prescribed as a means of preventing convulsive conditions in patients while taking ftivazid.

Prescribed for complex therapy of gestosis and alcoholism. For liver pathologies that appeared due to the use of ethanol or anti-tuberculosis drugs. It is often recommended to be taken by patients with hepatitis in order to enhance diuresis and enhance the effect of diuretic drugs.

Vitamin B6 is often prescribed to heart patients to regulate blood pressure. It is recommended to take it in the treatment of depressive conditions.

Often, preparations with this vitamin are prescribed for skin diseases - lichen dermatitis, frequent exacerbations of herpes and psoriasis. Prescribed for neurodermatitis, in the treatment of seborrhea, exudative diathesis.

Prescribed for the treatment of autism and epilepsy. The drug is indicated for patients with generalized anxiety.

What is the dosage and use of vitamin B6?

Pills:

The drug in tablets is taken after meals. For preventive purposes, take 0.002-0.005 g per day for adults.

What is the use of vitamin B6 in solution for injection?

The vitamin is administered intramuscularly:

For the treatment of sideroblastic anemia - 100 mg twice a week. At the same time, folic acid, cyanocobalamin and riboflavin are usually prescribed.

For the treatment of parkinsonism - 100 mg per day. The course is 20-25 injections. If necessary, treatment is repeated after 2-3 months.

In the treatment of depressive states of involutional age - 200 mg per day with intramuscular administration.

When treating convulsive syndrome (pyridoxine-dependent):

Adults: IV or IM - 30-600 mg per day.
Children: 10-100 mg per day.

What are the contraindications for vitamin B6?

Additional doses or treatment with B6 should not be prescribed to patients with hypersensitivity. For strict restrictions on the drug, vitamin B6, the instructions for use refer to patients with peptic ulcer disease, as well as those suffering from cardiac ischemia.

What are the side effects of vitamin B6?

When using drugs that are sources of this substance, allergic manifestations are possible, such as skin rashes, swelling, redness of the skin, itching. Hypersecretion of HCl may occur. Sometimes the patient complains of a feeling of squeezing in the arms and legs. Lactating women experience a decrease in lactation. With rapid administration of the drug, convulsions may occur.

You will learn even more detailed information about the properties and use of vitamin B6 from the original paper instructions, which you will find in the package with the drug.

Do not self-prescribe medications. Do not risk your own health, always seek a prescription from a doctor. Be healthy!

Vitamin B6 (pyridoxine) is a water-soluble B vitamin, poorly soluble in fats. Relatively stable at high temperatures, decomposes under the influence of light and oxygen. It is not synthesized in the body, sources of intake are food and pharmacological drugs.

What does the body need vitamin B6 for?

Benefits of taking pyridoxine

  • The enzyme transaminase is secreted, which is necessary for the processing of amino acids and the regulation of protein absorption.
  • Under stress, the production of biogenic amines increases.
  • The bioavailability of fatty acids improves.
  • The rate of biochemical reactions increases.
  • Reducing the synthesis of oxalic acid reduces the risk of development and relapse of urolithiasis.
  • Converts folic acid to its active form.
  • Dermatological diseases are prevented.
  • Thanks to the lipotropic effect, liver functioning improves.
  • Reduces premenstrual pain.

For systems and organs

Nervous system

  • Metabolism in the brain increases, memory improves.
  • Neurotransmitters are actively synthesized - serotonin, gamma-aminobutyric acid, dopamine and norepinephrine.
  • The supply of nervous tissue with nutrient substrates improves.
  • Prevents and eliminates muscle spasms and tremors.

Cardiovascular system:

  • Ischemia, atherosclerosis and myocardial infarction are prevented, blood is thinned and blood pressure is reduced.
  • The content of potassium and sodium in the blood and intercellular fluid is normalized.
  • Swelling of the face and limbs in chronic heart diseases is reduced.
  • Necessary for hemoglobin synthesis, reduces cholesterol levels in the blood, and prevents thrombosis.
  • Normalizes the functioning of the heart and increases its ability to relax during diastole.

Endocrine system:

  • The use of glucose becomes more efficient, its level in the blood changes without sudden surges and falls.
  • Maintains estrogen balance, preventing the appearance of tumors in women.
  • Necessary for the synthesis of most hormones.
  • Helps preserve vision in diabetes mellitus.

Vitamin B6 instructions for use

Solution for injection: administered subcutaneously, intramuscularly or intravenously slowly, 1-2 times a day. When administered intravenously, a single dose is diluted with 1-2 ml of water for injection or isotonic sodium chloride solution immediately before use.

Pills: Take orally with a small amount of liquid, regardless of food.

Pyridoxine for hair

If there is a lack of pyridoxine in the body, the hair dries out, breaks and splits. The scalp becomes oily, dandruff appears, and hair grows poorly. Vitamin B6 has gained wide popularity among cosmetologists to eliminate such problems.

Benefits for hair

  • Dry hair is hydrated because vitamin B6 retains water.
  • Hair growth increases.
  • Due to the soothing effect, skin itching is eliminated.
  • Hair stops falling out, thickens and strengthens.
  • Dandruff disappears.
  • The blood supply to the roots improves, the hair becomes smooth, increases in volume and begins to shine.

The most popular masks with pyridoxine from ampoules. They must be applied to unwashed hair, covering the head with polyethylene and wrapping it in a thick towel. In case of significant hair loss, masks should be applied every other day, for preventive purposes - 2 times a week.

Hair mask recipes

  1. Heat 2 teaspoons of burdock oil in a water bath and mix with an ampoule of pyridoxine. Apply to damp hair and leave for 2 hours.
  2. Beat a chicken egg and mix with a tablespoon of almond oil. Add 1 ampoule of pyridoxine and vitamin B12, mix and apply to dry hair overnight. Leave for an hour, rinse with warm water and go to bed. Wash your hair with shampoo no earlier than after 8 hours.
  3. Melt 2 tablespoons of honey and add 1 ampoule of vitamins A, E, B6 and B12. Stir and pour a teaspoon of sunflower oil and lemon juice into the mixture. Apply for an hour, then wash your hair with shampoo.

Vitamin B6 during pregnancy

During pregnancy, the body's need for pyridoxine increases by 1.5-2 times. It is prescribed in combination with magnesium, which increases the absorption of both elements (Magne B6). Pyridoxine eliminates morning sickness and leg cramps in the last trimester of pregnancy.

Indications for use::

  • Threat of miscarriage.
  • Detachment of the placenta.
  • Increased uterine tone.
  • Skeletal muscle cramps.
  • History of difficult pregnancy and complicated childbirth.
  • Frequent stress.
  • Tachycardia.
  • Arrhythmia.
  • Hypertension.

Vitamin B6 for children

A lack of pyridoxine in the diet of children can cause severe pathologies in the development of the nervous system. If it is deficient, the child sleeps poorly and suffers from night cramps. For babies, it is important that the mother gets enough vitamin B6. Before giving the drug to children under one year of age, consultation with a pediatrician is necessary.

Daily requirement

Increasing the dose by 25-30% is necessary:

  • While taking contraceptives and medications containing estrogen.
  • In the last week of pregnancy.
  • A week before the start of your period.
  • While taking steroid-based medications.
  • If you are overweight.
  • For acne and inflammatory skin diseases.

Vitamin B6 indications for use

Pyridoxine is prescribed for:

  • B6-hypovitaminosis.
  • Anemia.
  • Toxicosis during pregnancy.
  • Decreased leukocyte levels.
  • Meniere's disease.
  • Motion sickness and seasickness.
  • Inflammation in the gallbladder and liver.
  • Parkinsonism, neuritis, radiculitis and neuralgia.
  • Neurodermatitis, psoriasis and diathesis.
  • Diabetes mellitus.
  • Edema of cardiogenic origin.
  • Deterioration of cardiac contractility.
  • Increased blood pressure and risk of myocardial infarction.
  • Depression and increased nervous tension.
  • Urolithiasis.
  • Obesity.
  • Atherosclerosis.
  • Decreased immunity.
  • Deterioration of vision due to diabetes.
  • Increased hematocrit.
  • Hypercholesterolemia.

Assimilation

When administered intramuscularly, the bioavailability of pyridoxine is 100%. In food it is contained in the form of compounds that break down in the small intestine. With the blood, vitamin B6 enters the liver, where it undergoes dephosphorylation and then phosphorylation. The maximum concentration is observed in the liver, kidneys and myocardium.

What foods contain vitamin B6?

Where is vitamin B6 found in animal products:

  • Tuna, mackerel and sardine fillets.
  • Chicken and beef liver.
  • Chicken fillet.
  • Eggs.
  • Shrimp and oysters.
  • Beef and lamb.
  • Fermented milk products.

Plant products:

  • Hazelnuts, pine nuts and walnuts.
  • Beans.
  • Potato.
  • Sea buckthorn and pomegranate.
  • Horseradish and garlic.
  • Bell pepper.
  • Green peas, soy and lentils.
  • Bananas.
  • Millet.
  • Yeast.

Vitamin B6 deficiency

Pyridoxine deficiency is characterized by:

  • Excessive irritability, lethargy and mental dysfunction.
  • Insomnia and a feeling of causeless anxiety.
  • Decreased appetite and developmental delays in children.
  • Convulsive syndrome.
  • Flatulence.
  • Formation of uroliths in the kidneys and bladder.
  • Abnormal electroencephalogram readings.
  • Peripheral neuritis, polyneuritis of the hands and feet.
  • The development of anemia with a sufficient amount of iron in the body.
  • Inflammation of the skin and mucous membranes.
  • Stomatitis, rhinitis and conjunctivitis.
  • Glossitis and ulceration of the oral cavity.
  • Severe bleeding gums.
  • Convulsive conditions in children under 7 years of age.
  • Increased blood viscosity and its tendency to form clots, clogging blood vessels and causing thrombosis.
  • Nausea and vomiting.
  • The inability of the immune system to synthesize antibodies.

Overdose

Vitamin B6 is quickly metabolized and excreted in the urine. Exceeding dosages 50 times over several years does not lead to deterioration in health.
Increasing the dose hundreds of times can lead to:

  • Peripheral blood flow disorders.
  • Tachycardia and pain radiating to the left arm.
  • Migraines, drowsiness and dizziness.
  • Excitement and lack of coordination.
  • Paresthesia of the arms and legs.
  • A feeling of pressure on the limbs (stocking and glove syndrome).
  • Difficulty breathing.
  • Anaphylaxis, urticaria, itchy rash, redness of the skin, dermatitis, Quincke's edema and photosensitivity.
  • Nausea and vomiting.
  • Deterioration of the immune system's resistance to infections.
  • Heartburn and increased production of gastric juice.
  • Reducing folic acid content.
  • Partial baldness.
  • Disturbances in the blood coagulation system.
  • Fainting and convulsive syndrome when large doses are administered intravenously.
  • Inhibition of milk production in nursing mothers.

Long-term overdose causes a decrease in the amount of protein in skeletal muscles, liver, kidneys and heart.

Drugs and release forms

Vitamin B6 in ampoules – price 11 UAH/35 RUR for 10 ampoules of 1 ml.

Compound: pyridoxine hydrochloride – 0.05 g, water for injection – up to 1 ml.

Vitamin B6 tablets – price 9 UAH/28 RUR for 10 tablets.

Compound:

  • Active ingredient– priridoxine hydrochloride 0.05 g.
  • Additional components: microcrystalline cellulose, lactose monohydrate, anhydrous colloidal silicon dioxide, talc, magnesium stearate.

Compatibility

The following drug interactions have been described:

  • When taken simultaneously with diuretics, pyridoxine enhances their effect.
  • Combined use with hormonal contraceptives, cycloserine, penicillamine, isoniazid, hydralazine sulfate, ethionamide and immunosuppressants reduces the effectiveness of vitamin B6.
  • Pyridoxine partially blocks the effect of drugs for the treatment of Parkinson's disease and weakens the pharmacological effect of phenytoin.
  • When taken in combination with corticosteroid hormones, the content of pyridoxine in the body decreases.
  • Simultaneous use with glutamic acid and asparkam increases the brain's resistance to hypoxia.
  • The parallel use of vitamin B6 and cardiac glycosides stimulates the production of contractile proteins in the heart muscle.
  • Pyridoxine prevents complications from taking tricyclic antidepressants caused by their anticholinergic effects (decreased salivation, anuria).
  • Simultaneous administration with chloramphenicol derivatives reduces the risk of ophthalmic pathologies.
  • Vitamin B6 is compatible with vitamin B12, but mixing them in the same container is not recommended.
  • It is not advisable to mix pyridoxine with alkali solutions, iron derivatives and solutions of strong oxidizing agents.
  • Do not mix vitamin B6 in the same container with solutions of adrenergic agonists, ampicillin sodium salt, amphotericin B, ascorbic acid, phytomenaion, dipyridamole, sodium oxyferiscorbone, phenothiazine derivatives (chlorpromazine), furosemide, etamsylate and euphilin.

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Kalorizator 2020 - Vitamins, instructions for medications, proper nutrition. All information is for informational purposes only. Be sure to consult a doctor during treatment.