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Pimafucin suppositories during pregnancy: instructions, use. Pimafucin - a quick solution to delicate problems during pregnancy Pimafucin cream instructions for pregnant women

    The latter disease is better known as thrush. It is known that normal physiological changes and hormonal changes in a woman’s body during pregnancy contribute to the development of thrush, and it is observed in almost half of pregnant women. Therefore, Pimafucin during pregnancy is in most cases prescribed to treat this particular disease.

    Contraindications and side effects

    Pimafucin should not be used by pregnant women if allergic reactions occur. But, as practice shows, such cases are quite rare.

    Also, when using the drug, side effects may occur, which should subside over time. Treatment with tablets can cause nausea, vomiting, diarrhea in a pregnant woman, and with suppositories and cream - burning, itching, redness, and slight swelling at the site of application.

    The occurrence of these reactions is not a reason to discontinue the drug. However, if they cause significant discomfort, the pregnant woman should inform the doctor about them and clarify the possibility of using Pimafucin further.

    Effect on the pregnant woman and fetus

    At the moment, Pimafucin is considered the safest treatment for thrush in pregnant women, since no negative effects of the drug on the pregnant woman and the embryo (fetus) have been identified.

    When entering the body, Pimafucin is practically not absorbed into the blood, therefore it does not affect the condition and development of the embryo (fetus). Therefore, it can be used at any stage of pregnancy. At the same time, preference is given to treatment with suppositories and creams rather than tablets.

    Dosage and application features

    The course of treatment with Pimafucin during pregnancy is determined by the doctor in each specific case. Usually, for mild thrush, pregnant women are prescribed 1 suppository (100 mg) at night for 3-6 days. The suppositories are inserted deep into the vagina in a lying position.

    In severe cases, longer treatment with suppositories together with tablets is possible: 1 tablet (100 mg) 4 times a day for 7-10 days.

    Reviews about the drug

    Judging by the reviews, Pimafucin helped some, but not others. Thus, some pregnant women felt better after taking several suppositories. Others needed longer treatment, and for others it did not help at all, or the effect of using the drug only lasted for a few days, and then the thrush reappeared.

    It is worth noting that none of the pregnant women mentioned allergies or side effects. When using suppositories, the only concern was increased vaginal discharge, which was the remains of suppositories.

    Also, some doctors consider Pimafucin to be an outdated and ineffective drug and do not prescribe it to pregnant women.

    What to replace

    In addition to Pimafucin, there are other drugs for the treatment of thrush during pregnancy. The most popular of them:

  • Sertaconazole, Econazole, Zalain - can be used only in cases where the benefit of taking them outweighs the risk;
  • Livarol, Clotrimazole, Gino-Pevaril, Neo-Penotran - cannot be used in the 1st trimester, but in the 2nd and 3rd trimester with a predominance of benefit over risk;
  • Terzhinan - can be used from the 2nd trimester, in the 1st - if the benefit outweighs the risk;
  • Gynoflor, Normoflor - are allowed throughout pregnancy, they are complexes of lactobacilli to normalize the vaginal microflora, recommended for the complex treatment of thrush.

Thus, none of the presented drugs is completely safe for a pregnant woman and the embryo (fetus), and bacterial complexes, if used separately and not in combination with other antifungal drugs, as a rule, are not sufficiently effective.

To treat thrush, pregnant women should not forget about other non-drug methods, and these are:

  • a diet that limits the consumption of baked goods and sweets and includes products with bifidobacteria (kefir, yogurt), vegetables;
  • genital hygiene aimed at eliminating favorable conditions for the development of fungi (removing excess moisture after washing, using cotton panties);
  • baths with herbal infusions (chamomile, calendula).

All these measures, unfortunately, will not replace the pregnant woman taking medications, but will contribute to a speedy recovery.

Drug price

Pimafucin belongs to the drugs of the middle price category. Its price depends on the form of release and quantity in the package.

Estimated cost of Pimafucin in pharmacies:

  • in the form of a cream 2% 30 g - 250-300 rubles;
  • in the form of suppositories 100 mg No. 3 - 270-310 rubles;
  • in the form of suppositories 100 mg No. 6 - 490-620 rubles;
  • in the form of tablets 100 mg No. 20 - 450-550 rubles.

During pregnancy, a huge number of changes occur in a woman’s body, and they are not always positive. Hormonal changes, increasing stress on the body and a common decrease in immunity are the main factors that provoke the occurrence of vaginal candidiasis. Thrush is an unpleasant but harmless disease that can be easily treated with medication. The main thing is not to start it to the stage when serious therapy is already required. This is especially true for pregnant women, because an increase in blood sugar levels provokes the growth of fungal microorganisms.

At this time, there are a huge variety of antifungal agents, but not all are allowed to be used while expecting a child. Pimafucin is a broad-spectrum antifungal and antibacterial agent, which compares very favorably with other products presented in pharmacy kiosks. A huge advantage is the ability to use it at all stages of pregnancy. What also attracts women is the low toxicity of the product and the large number of release forms.

Pimafucin is a complex action agent that has a destructive effect on fungi and bacteria. The spectrum of action of this antibiotic is very wide, which makes it effective against most pathogenic microorganisms.

The medicinal properties are due to the influence of the main active ingredient – ​​natamycin. This component not only has a detrimental effect on the cells of pathogenic bacteria, but also prevents the spread of the disease throughout the body. The effectiveness of the drug in the case of thrush is due to the fact that natamycin has an inhibitory effect on the fungus of the genus Candida, which is the causative agent of this unpleasant disease.

What pathogenic microorganisms does the drug affect:

  • pathogenic fungi;
  • yeast-like bacteria;
  • dermatophytes, etc.

Each specific case uses its own form of medication. The choice of treatment tactics depends on the location of the lesion, as well as the stage at which the disease is located.

Pharmacological forms of release:

  • Vaginal suppositories (suppositories) – the package contains three suppositories containing 100 mg of active ingredient.
  • Cream for external use, with a two percent concentration of natamycin. The amount of ointment in the tube is 30 ml.
  • Tablets, the shell of which dissolves only in the intestines, and therefore the maximum therapeutic effect is achieved. The dosage is 100 mg. The number of tablets in a jar is 20 pcs.

A significant advantage of Pimafucin is that it does not act systemically, and therefore its use is safe at various stages of pregnancy, including in the first trimester. There are also very few contraindications associated with this. The drug is not approved for use only in cases where individual intolerance to one or more components of the drug occurs.

Indications and contraindications

First of all, it is worth noting that the use of any medical drug, no matter how harmless it may be, is possible only under the supervision of a specialist. Self-medication during pregnancy is strictly prohibited. Only a doctor can assess the risks and make a decision regarding the advisability of using a particular drug.

Indications for use of Pimafucin

  • Infectious diseases whose pathogens show sensitivity to the effects of natamycin.
  • Fungal infection of the gastrointestinal tract, caused by the uncontrolled use of antibiotics for the treatment of infectious diseases.
  • Candidiasis affecting the small intestine.
  • Fungal infection of the ear canal.
  • Mycosis of the skin and its appendages (nail plates), including its chronic form.

Most often, it is the latter disease that is an indication for the use of an antimicrobial agent. Hormonal changes and a general decrease in immunity are the main factors provoking the growth of the population of pathogenic fungi in the vagina. Against the background of candidiasis of the mucous membrane, an inflammatory process occurs, which, over a long period of time, can provoke. In addition, during the delivery process, the child may become infected, which will lead to candidal stomatitis.

Pimafucin suppositories during pregnancy, according to the instructions for use, can be used at any stage of pregnancy. This is due to the fact that natamycin has only a local effect and is not absorbed into the blood, and, accordingly, cannot pass through the placental barrier.

Contraindications for use

A direct contraindication to the use of the drug is intolerance to the components of the drug. This can provoke an allergic reaction, which will manifest itself in the form of itching and burning in the vaginal area. Otherwise, the drug is absolutely safe.

The use of the product may intensify the manifestations. This often happens on the first day after starting treatment. But later the symptoms go away without any intervention. Therefore, you should not worry about a slight deterioration in your condition.

Can Pimafucin be used during pregnancy?

According to preliminary studies that occurred during testing of the drug, Pimafucin does not cause toxic effects on the fetus. However, despite this, the use of a natamycin-based product is possible subject to certain conditions.

  • Immediately after the appearance of unpleasant symptoms, you must contact a gynecologist to get all tests done. Initially, there may not be a characteristic cheesy discharge, but constant itching in the perineum definitely indicates the development of an inflammatory process.
  • Medicine for thrush can only be prescribed by a doctor and only after appropriate tests.. Not all medications are equally permitted during pregnancy.
  • Based on the clinical course of the disease, a specific treatment tactic is selected. Mild forms do not require the use of tablets; local treatment using suppositories and ointments is quite sufficient. However, in severe cases of candidiasis or chronic inflammation, it is necessary to choose a systemic approach to therapy.
  • Taking the drug should not exceed two weeks. If recovery does not occur during this period, then a different treatment tactic is chosen.

Pimafucin in the first trimester

In the early stages of gestation, the formation of absolutely all organ systems of the unborn baby occurs. Therefore, the effect of medications on a growing organism can contribute to the occurrence of pathologies. This is precisely why caution is associated with the use of medications during this period.

Under what conditions can the drug be used in the early stages of pregnancy:

  • The use of an antifungal agent is possible in cases where the use of milder methods does not have an effect. Initially, the gynecologist may prescribe the use of douches and herbal baths. And only if they are ineffective does he prescribe a prescription for the use of the medicine.
  • The use of tablets at this stage is inappropriate. Despite the fact that the instructions do not imply a negative effect of the main active substance on the formation of the fetus, it is not worth exposing the child to additional danger.
  • Pimafucin in the form of suppositories is allowed to be used during pregnancy in the 1st trimester. The action of the drug in this case is directed to the area of ​​inflammation and, at the same time, does not have a negative effect on the child.

Did you know? The cause of thrush in the first trimester is most often associated with decreased immunity. This is completely physiological, because the body reduces its protective functions in order to avoid antenatal death of the fetus due to its rejection by the mother’s immune system.

Pimafucin in the second trimester

The drug is taken for the same indications as at an earlier date.. By this time, the placental barrier has already been formed, and therefore the child is perfectly protected from external influences. Pimafucin is completely approved for use during pregnancy in the 2nd trimester. The tablet form can also be used, but only for direct indications, when local exposure is not enough.

To maintain healthy microflora, concomitant use of Clotrimazole suppositories may be prescribed. It is used in the same course as Pimafucin.

Pimafucin in the third trimester

The closer to the time of delivery, the greater the need for timely treatment of thrush. The fact is that here we are talking about the health of the unborn child, and not about the well-being of the mother.

There are certain rules for taking the drug in the third trimester:

  • The pregnant woman must be completely healthy before giving birth. Candidiasis is dangerous for the baby and increases the risk of postpartum inflammation.
  • To achieve better results, preference is given to a combination form of therapy.
  • Pimafucin - suppositories during pregnancy in the 3rd trimester are used both in conjunction with tablets and after completion of the main course. The decision regarding the regimen of use is made by the gynecologist, based on the course of the disease.
  • Taking the drug for longer than two weeks is not advisable. In this case, the therapeutic effect is not enhanced, but only increases the risk of adverse reactions.

Instructions and dosage

The duration and regimen of treatment should always be chosen by the attending physician.. Self-medication while expecting a child can lead to unpredictable consequences. Each form of the drug involves different methods of use, so it is necessary to dwell in more detail on each of them.

Vaginal suppositories

Pimafucin suppositories can be used during pregnancy according to the instructions, regardless of the gestation period. The course of treatment ranges from three to seven days, depending on the severity of the situation. The amount of active ingredient in each suppository is 100 mg.

A huge advantage of using this form of the drug is its complete dissolution and uniform distribution over the entire inner surface of the vagina. Thanks to this, complete coverage of the affected area and destruction of pathogenic bacteria is achieved. The product primarily affects the cell membranes of fungi, destroying them.

The administration of the suppository is prescribed once a day before bedtime. The product dissolves quite quickly and can flow out of the perineum when positioned vertically.

Cream for external use

This form is used to treat fungal infections of the skin and nail plates. Local use of ointment on the affected area is necessary. The course of treatment is from one to two weeks, subject to regular use of the drug two to four times a day.

In very difficult situations, treatment is prescribed to both partners. For example, if thrush is detected in a woman, it is recommended that the creamy form be used by a partner. In this case, the head of the penis is lubricated several times a day for the purpose of preventive treatment of candidiasis.

The concentration of the active substance in the cream is 2% of the total number of components.

Tablet form

Pimafucin tablets during pregnancy are used as part of joint therapy for infections that cannot be treated only locally. Use in the early stages of pregnancy is possible, but only if the expected benefits outweigh the possible risks to the fetus. Late use is completely safe.

The product is used four times, one tablet, for a period of seven to ten days. It is advisable to take tablets after meals to avoid unpleasant gastrointestinal symptoms. If the dosage regimen and dosage are followed, the use of the drug does not cause complications in either the pregnant woman or the fetus. The dosage is 100 mg of active substance per tablet.

Side effects

Depending on the form of the product that is used, various unpleasant symptoms are observed at the site of use. Usually the drug is well tolerated by patients and adverse reactions do not occur, but they are still possible.

Side effects from the use of Pimafucin:

  • The tablet form can cause gastrointestinal disorders. Immediately after starting use, nausea, bloating and heartburn may occur for a couple of days. However, as the course continues, the symptoms disappear.
  • After applying the cream or inserting a suppository, burning and redness may occur at the site of use.. This indicates the presence of a mild allergic reaction, but most often does not require any additional therapy.

Pregnancy is a special period in a woman’s life when she has to take the highest responsibility when choosing medications and strictly follow the doctor’s recommendations. This principle applies to medicines for all diseases, including those that seem to be “traditional” pregnancy companions. Such common diseases include vaginal candidiasis, or thrush (more details:). There are many different remedies for its treatment, but doctors prefer to prescribe the safest of them to pregnant patients, namely, pimafucin. Pimafucin is a broad-spectrum antifungal antibiotic that has no contraindications for use during pregnancy. In most cases, pregnant women are prescribed local therapy with pimafucin in the form of vaginal suppositories. The duration of treatment depends on the individual characteristics of the body and the course of the disease and can range from 3 to 9 days. The drug is inserted into the vagina, one suppository at night, before bed.

What is the indication for prescribing pimafucin?

During pregnancy, due to hormonal changes in a woman’s body, its immune defense is weakened, the vaginal microflora changes, and these factors create a favorable opportunity for fungal infection. Against this background, a woman may develop inflammatory processes such as vaginitis, vulvitis or vulvovaginitis. They affect the skin and mucous membranes of the external genitalia and vagina, causing itching, burning and discomfort. Like any inflammatory disease, candidal vaginitis, vulvitis and vulvovaginitis adversely affect the course of pregnancy. In cases of particularly severe complications, candidiasis causes thinning and weakening of the fetal membranes under the influence of fungal waste products, which can lead to their premature rupture. In addition, during childbirth, a child may become infected with candidiasis as it passes through the birth canal. Therefore, the doctor needs, on the one hand, to prescribe an effective treatment for thrush, and on the other hand, to select a drug that will not negatively affect the fetus and the course of pregnancy. Such a drug is pimafucin. Its active substance, natamycin, has a local effect on fungal cells, disrupting the integrity of their membranes and thereby causing the death of microorganisms. At the same time, the drug itself has only a local effect and is not absorbed from the surface of the skin or mucous membrane into the blood, that is, it does not penetrate the uteroplacental barrier.

How is pimafucin therapy carried out?

There are several dosage forms of this drug. Treatment with pimafucin during pregnancy is most often carried out locally. A perinatologist prescribes therapy for a pregnant woman with pimafucin vaginal suppositories containing 100 mg of natamycin. In this case, the suppository is inserted deep into the vagina once a day before going to bed at night in a lying position. After administering the suppository, it is advisable not to get up for several hours, since under the influence of body heat the suppository quickly dissolves to form foam, which evenly covers all mucous membranes. If you stand up at this moment, the active substance will quickly flow out of the vagina and the medicinal effect will be minimized. In most cases, one treatment course of pimafucin suppositories is enough to cure genital candidiasis.


However, in some cases, the fungal infection occurs in a generalized manner, that is, in addition to the vagina, it also affects internal organs. With generalized candidal infection of the body, the fungi are located in the intestinal walls, from where the genital organs are constantly infected. In this case, local treatment alone will be ineffective, so it is combined with systemic therapy, prescribing pimafucin tablets in addition to suppositories. The tablets are sold in packs of 20, each tablet containing 100 mg of natamycin.

To prevent relapses of vaginal candidiasis, it is necessary that the woman’s partner also be treated. Even if he does not have any symptoms of thrush, the causative agents of this disease can be located under the foreskin, on the head of the penis and, once on the vaginal mucosa, begin to actively multiply there. Therefore, the partner of a woman who is being treated for candidiasis is recommended to carry out local therapy with pimafucin in the form of 2% cream. The cream is applied to the skin and mucous membranes one or several times a day. Treatment continues for several more days after the symptoms of the lesion disappear in both partners.

With severely weakened immunity, candidiasis sometimes affects the mucous membranes of the oral cavity. In this case, doctors recommend using pimafucin in the form of a 2.5% suspension for local treatment. However, such damage to the oral cavity is quite rare in adults.

What is the duration of treatment with pimafucin during pregnancy?

The duration of local treatment with suppositories is determined by the intensity of the disease and can range from 3 to 9 days.
For systemic therapy, it is recommended to take 1 tablet of pimafucin 4 times a day for 7-10 days. Pimafucin does not have a teratogenic effect on the fetus, does not penetrate from the intestines into the mother’s blood, that is, does not cause any harm to the child, therefore its use is permitted throughout the entire period of pregnancy.

Quite rarely, there is a side effect of the drug when taken orally, which manifests itself in the form of nausea and diarrhea. It does not require discontinuation of treatment and goes away on its own after some time. When applied topically, a feeling of discomfort and burning may occur.
An overdose of pimafucin does not cause any toxic damage to the body.

The only contraindication to the use of pimafucin is the patient’s hypersensitivity to the components included in the drug.

Pimafucin during pregnancy: Reviews

In some cases, treatment with pimafucin may not have a positive effect, but most often this happens when the drug is not taken for a long enough time.

However, in the vast majority of cases, pimafucin, if not completely destroys the causative agents of fungal infection, then significantly facilitates its course, relieving unpleasant and even painful symptoms. Here are reviews from several women about treatment with pimafucin:

Catherine I had already encountered thrush before pregnancy. But then she took Diflucan, which helped her well. In the first weeks of pregnancy, noticing the familiar symptoms of thrush, Ekaterina wanted to treat it in the usual way, but before taking the Diflucan tablet she decided to read the instructions for the drug. Seeing that this drug is contraindicated for use during pregnancy, the woman did not self-medicate, but consulted a doctor. She was prescribed a six-day course of pimofucin suppositories. Ekaterina felt relief after the first day of treatment. After a full course of suppositories, the symptoms of thrush did not recur until the 30th week of pregnancy. At this time, the disease relapsed, and Ekaterina was prescribed complex therapy with pimafucin tablets and suppositories. After a week's course of treatment, the symptoms of thrush disappeared and did not appear again.

Xenia I first encountered thrush at the 19th week of pregnancy. The itching and burning sensations were very unpleasant. The doctor prescribed the woman pimafucin suppositories for a three-day course. The symptoms of thrush went away, but the improvement was short-lived. Two weeks later, Ksenia again came to see the doctor with complaints about thrush. This time she was prescribed pimafucin in suppositories for 6 days, in tablets, 1 piece 4 times a day for a week, and recommendations were given for treating her husband with 2% pimafucin cream. After all the doctor’s orders were completed, thrush no longer bothered Ksenia.

Svetlana I didn’t notice any unpleasant symptoms, but at a routine appointment at the antenatal clinic at 12 weeks of pregnancy, the perinatologist informed her that a significant amount of Candida fungus was found in the smear, and treatment was necessary. Svetlana did not follow the doctor’s recommendations because she was afraid of harming the child with “extra chemicals.” After a few weeks, she began to notice a lot of curdled discharge, which scared her. Having visited a doctor whom she completely trusted, the woman asked to choose the safest medicine possible. She was recommended local treatment with pimafucin suppositories for 6 days. This time Svetlana followed all the doctor’s instructions, and the treatment helped her.

Pimafucin during pregnancy is one of the safest drugs, so you should not question the recommendations of a doctor who prescribes a course of pimafucin to a pregnant woman. In the vast majority of cases, this medicine will help the expectant mother solve her problems, and most definitely will not cause the slightest harm to the fetus.

Very soon you will become a mother, it's time to take care of your health. It is necessary to take useful substances, for example, which your attending physician will advise you to do, get more rest and receive only positive emotions. After all, just a little more and you will give life to a little baby!

But such a wonderful state of pregnancy also has its unpleasant moments. And if you quickly get used to periodic pain in the chest and abdomen, and it helps you cope with toxicosis, then something as common as thrush can make you nervous.

About thrush


Thrush (candidiasis) is a common disease among women, including expectant mothers. Weakening of immune function leads to the manifestation of symptoms of this disease, starting from the first months of pregnancy until the end of the term.

Often candidiasis is accompanied by such phenomena as itching, burning, mucous discharge of a cheesy appearance with a pungent odor of acid and, as a result, a certain discomfort. Moreover, if proper treatment is not carried out in time, the symptoms intensify and can have dire consequences.

Therefore, doctors strongly recommend treating thrush in its early manifestations, even in such a difficult period when medications are not entirely appropriate. There is a certain group of antifungal drugs that are approved and can be recommended to expectant mothers.

One of the most harmless and non-hazardous drugs is Pimafucin. It is produced in the form of: tablets and suppositories (vaginal suppositories); it is possible to use Pimafucin cream during pregnancy.

A doctor may also prescribe it as an alternative. In addition to them, many doctors advise the use of special gels, as well, but rather for preventive purposes.

Vaginal suppositories are most often prescribed to pregnant women. The main advantage of Pimafucin lies in the active substance - natamycin, which does not penetrate the placental barrier and minimizes the risk of pathological effects on the fetus. Although for short periods it is prescribed exclusively for strict indications.

Frequently asked questions about the drug

Any pregnant woman is quite susceptible and suspicious, so anxiety associated with taking any medications is completely justified, including the use of Pimafucin. Let's take a closer look at the questions that most often interest expectant mothers.

Expectant mothers need to understand which medications can be used during pregnancy and which ones should be avoided. So, we will be happy to tell you about taking such an antiviral medicine as. After all, sometimes mommy can catch a cold.

It would also be useful to learn about medications that will help with iron deficiency. Therefore, we have prepared for you information about taking Sorbifer Durules during pregnancy. Don't get sick!

Indications for use

The use of this drug is prescribed in case of manifestation of the above symptoms and by taking it from the vaginal environment it confirms the presence of pathogenic microflora.

If there are no pronounced symptoms, treatment may be postponed until the postpartum period. That is, an important indicator for the appointment is precisely the presence or absence of discomfort.

The effect of the drug on the body

Despite the fact that the active ingredient of the drug, natamycin, is a broad-spectrum antibiotic, you should not be afraid of it.

According to the instructions for use of Pimafucin, it is practically not absorbed by the skin and mucous membranes. This means that the substance does not enter the bloodstream, and therefore does not pose a threat to the life of the unborn baby, even in large quantities.

A contraindication to the use of Pimafucin is individual non-acceptance of individual components of the drug or allergic reactions that have ever occurred during its use.

  • Film-coated tablets (20 pieces per package);
  • Suppositories or vaginal suppositories (3 pieces per package);
  • Cream for external use 2% (30 g in tube);
  • Suspension for topical use 2.5% (20 ml in a bottle).

One tablet or suppository of Pimafucin contains 100 mg of natamycin, 1 gram of cream - 20 mg of natamycin, 1 ml of suspension - 25 mg of natamycin.

Tablets and cream are prescribed for fungal infections and diseases caused by fungi, such as:

  • acute candidiasis in patients with immune deficiency, cachexia, as well as after treatment with corticosteroids, antibiotics, cytostatics;
  • vaginitis, vulvitis, vulvovaginitis caused by fungi Candida ;
  • candidiasis of the skin and nails;
  • otomycosis, external otitis, either caused by fungi or complicated by candidiasis;
  • dermatomycosis.

Vaginal suppositories are prescribed for vaginitis, vulvitis, vulvovaginitis caused by fungi Candida . Tablets are also prescribed for intestinal candidiasis.

Doses of use and duration of treatment are determined by the doctor on an individual basis. Tablets for intestinal candidiasis are taken 1 pc. 4 times a day, duration of administration is 7-14 days.

Vaginal suppositories - once a day at night; after inserting the suppository, it is advisable not to get up for several hours. After the symptoms of the disease disappear, treatment with drugs should be continued for several more days.

In most cases, pregnant women are prescribed local therapy with Pimafucin in the form of vaginal suppositories. The duration of treatment depends on the course of the disease and is 3-9 days. Suppositories are inserted deep into the vagina once a day at night, before bed.

With generalized candidiasis, the fungus also affects internal organs; it settles on the intestinal walls, which is a source of systematic infection of the genital organs. In this case, local treatment is ineffective and complex therapy is prescribed, combining the use of suppositories and tablets.

If the disease is chronic or advanced, Pimafucin cream is additionally prescribed. To prevent relapses, the partner of a pregnant woman must also be examined and treated. Even if he does not have symptoms of thrush, the causative agents of the disease may be under the foreskin.

When the immune system is severely weakened, candidiasis sometimes affects the oral mucosa; in this case, Pimafucin is used in the form of a suspension. However, this is rare in adults.

The only contraindication to the use of Pimafucin is hypersensitivity to the components in the drug.

Side effects:

  • From the gastrointestinal tract when taken orally: nausea and diarrhea, which may occur in the first days of administration and go away on their own during treatment.
  • Local reactions: mild irritation, burning sensation when using cream and vaginal suppositories.

There have been no cases of overdose with Pimafucin.

Pimafucin suppositories are non-toxic even when used in large doses. To have an effect from their use, it is necessary to put 2-3 packages, since this is still a rather weak drug. However, since it is the safest during pregnancy compared to other drugs, it is better to give preference to Pimafucin.

Every second pregnant woman develops candidiasis, vaginosis, vaginitis or another bacterial infection of the vaginal mucosa. During the entire period of pregnancy, several cases of reappearance of fungal infection of the genital tract may occur, so it is necessary to select a remedy that can relieve the expectant mother of thrush both in the first trimester and throughout the subsequent months of bearing the baby. This is precisely why Pimafucin suppositories are so popular during pregnancy.

Candidiasis (thrush) for a woman seems like a “trifling” disease, because even before pregnancy, this disease can proceed for years without any special symptoms (often only a cheesy discharge is observed, and the woman does not attach any importance to it). And while carrying a baby, when a woman undergoes scheduled genital smears, thrush is discovered and panic begins. After all, now a woman is a future mother, and she is responsible for the health of the child.

Why is thrush dangerous during pregnancy?

For an expectant mother, thrush does not pose a great danger, but the risk of intrauterine infection of the baby or its infection during passage through the birth canal is quite high.

Infected children are forced to suffer from thrush of the mouth and skin folds for the first months of their lives (while their treatment is ongoing), moreover, their bodies are weakened and the babies often get sick.

The disease can worsen, and then the child's respiratory and digestive tracts are involved.

It must also be said that chronic candidiasis in a woman occurs along with other infectious diseases of the genital tract, which are really dangerous for the child.

A long-term fungal infection can lead to a thinning of the mucous surface of a woman’s vagina, causing its structure to become fragile and very vulnerable. Sexual intercourse or douching can cause microcracks to appear on the walls of the vagina, through which it will be easier for any other infection to enter the body of the mother and, accordingly, the child.

Therefore, if a fungal or bacterial infection is detected during an examination of the discharge, the doctor will definitely prescribe special medications to the expectant mother.

Indications for the drug and its principle of action

According to the patient's complaints about:

  • itching of the labia and/or inside the vagina;
  • burning and irritation in the vagina;
  • copious milky or cheesy discharge with a sour odor;
  • discomfort/pain during intercourse

and test results that confirm an increase in the number of Candida fungi in the smear - the antifungal drug Pimafucin is prescribed.

Pimafucin is officially approved for use during pregnancy. This drug for thrush has a broad spectrum of action and is highly active against yeast fungi, especially Candida albicans.

The main substance of the drug disrupts the structure and function of fungal cells, thereby destroying them.

Dosage and method of administration

Pimafucin suppositories. Suppositories for thrush are classified as topical preparations. The components do not penetrate the uteroplacental barrier, as they are not absorbed into the blood. With the help of this therapy, a woman quickly gets rid of the symptoms of candidiasis without harm to the unborn child.

It is only necessary to insert 1 suppository into the vagina as deeply as possible once a day before bedtime. The course of treatment is from 3 to 6 days.

If for some reason the candle needs to be placed during the day, you will need to remain in a supine position for several hours. After all, the drug gradually dissolves in the vagina, turning into foam, and evenly covers its walls. When walking, the melted suppository quickly flows out, which reduces the medicinal effect several times. In 85% of cases, one course of Pimafucin is enough to cure candidiasis.

Pimafucin suppositories can be used regardless of the stage of pregnancy. If there are cases of repeated occurrence of infection, the drug can be used without restrictions.

Pimafucin tablets. If candidiasis occurs in a severe form, then suppositories alone are not enough. There are other dosage forms of the drug that help fight the generalization of the infection.

Basically, the localization of fungal infection occurs in the intestines, from where there is constant infection of the vagina. In such cases, the gynecologist prescribes tablets in addition to suppositories - 1 tablet. 4 times a day in a course of 10-20 days.

Comprehensive treatment effectively reduces the risk of relapse of candidiasis.

But remember! Treatment by the woman alone is not enough. If a partner has candidiasis, then during unprotected intercourse the fungal infection will spread again and affect the vaginal walls. Therefore, it is recommended to avoid sexual intercourse while using suppositories. In addition, during friction, a negative effect can occur on the thin, fungal-affected epithelium of the woman’s genital tract. The partner needs to undergo treatment together with the woman, since pathogens may remain on the penis under the foreskin. When they come into contact with the mucous membrane, they actively multiply again.

Cream Pimafucin. Pimafucin cream is available for men, which must be applied to the affected areas of the genital organ from one to 4 times a day. The duration of treatment is individual. After the complete disappearance of symptoms, it is necessary to apply the ointment to the genital organ for several more days to avoid incomplete cure.

The cream is also prescribed for local treatment of newborns.

Contraindications and side effects

A contraindication to the use of the drug is considered to be individual intolerance to the components.

Patients with rare congenital intolerance to fructose and galactose, as well as sucrose-isomaltase deficiency, should take into account the composition of Pimafucin. If you have the above diseases, then treatment is carried out under the supervision of a doctor.

As a side effect when taking the pills, a pregnant woman may experience nausea or diarrhea. There is no need to cancel treatment in this case. This is a normal reaction of the body to the drug, and after some time the unpleasant symptoms disappear.

In the first hours of administration, Pimafucin suppositories may (but not necessarily!) cause a burning sensation or mild irritation in the vagina. These unpleasant sensations are caused by the activation of the drug and the massive death of the pathogen. Gradually the mucous membrane clears and the burning sensation disappears.

Cases of overdose with Pimafucin are unknown. During clinical and laboratory studies, no toxic damage to the body of the mother and child was observed due to the high dose of the drug. Therefore, doctors safely prescribe Pimafucin in the early stages of pregnancy.

No interactions with other drugs were found.

Pregnancy is often accompanied by candidal colpitis, which brings a lot of inconvenience to a woman. And you always have to choose between effective and safe drugs, especially before 12 weeks, when any negative impact can disrupt the normal process of embryo development.

One of the popular and accessible remedies is pimafucin, which is approved for use in the early stages of pregnancy without any restrictions. How and when to use correctly and what is better to choose – suppositories, cream or tablets?

Composition and properties of the drug

Pifamucin is based on the active substance natamycin, a drug that belongs to the polyene group and has antifungal activity. It is noteworthy that there is no sensitivity to this drug from, for example, candida. This opens up wide possibilities for drug therapy.

This drug is available in various forms - tablets, ointments and suppositories. Therefore, for each clinical option, you can choose the most suitable one.

As for the tablets, each contains 100 mg of the main active ingredient.


How it works

Natamycin interacts with certain structures of the pathogen shell. This way it disrupts the foundations of their life, which ultimately leads to death.

The peculiarity of the capsules is that when taken orally, they act only in the intestines, without being absorbed into the systemic bloodstream. The same is true when using skin ointments - only local action. That is why pimafucin and its analogues can be safely used during pregnancy, even in the early stages.

Indications for use

Pimafucin is used to treat all conditions where pathogenic microorganisms, in particular fungi, are sensitive to it. Preference is given in the following situations:

  • For vulvovaginitis, vulvitis (involving not only the vagina, but also the external genitalia).
  • If necessary, carry out sanitation against fungi in the intestines. Often this need arises in cases of serious immunodeficiency conditions (including HIV), while taking cytostatics and antibacterial drugs, hormonal drugs.
  • In case of systemic fungal infection. In this situation, pimafucin can be used both externally and internally.

Before using the drug, you should make sure that the pathogenic flora is sensitive to it.


Is it possible during pregnancy?

Pimafucin can be safely used during pregnancy throughout the entire gestation period. The drug does not have a harmful effect on the developing fetus. This is largely due to the fact that the drug, when taken orally, is not absorbed into the systemic bloodstream, just as when used topically. As a result, the chemical components simply do not reach the fetus.

Despite this, during pregnancy, especially in the early stages, preference is given to the use of suppositories, and only for more extensive indications and serious situations is it better to use oral tablets.

Watch the video about the drug:

Application schemes

The regimen of use and the form of the drug depend on the goals pursued and the general condition of the woman.

Pills

The average dose is 1 tablet 4 times a day. Children are usually prescribed only 2 times a day. The duration of treatment varies. So, it is approximately as follows:

  • for intestinal candidiasis, you should take the drug for a week;
  • in case of nail fungus, the minimum duration of therapy is 2 - 3 months until a new nail grows;
  • if the tablets are used as an addition to local treatment, for example, for vulvitis or skin pathologies, the course averages 2 to 3 weeks.

Candles

Suppositories are used to treat fungal infections of the external and internal genital organs.

Pimafucin (suppositories) in early pregnancy is prescribed one suppository deep into the vagina once a day. It is best to administer the medicine while lying on your back, after which it is recommended to remain in a horizontal position for some time so that the dissolved suppository does not leak out. With this in mind, the product is usually applied at night.

The average course is from 3 to 6 - 7 days. Depending on the clinical picture, treatment can be extended to 2 - 3 weeks or tablet forms can be added.

Cream

The cream is used for lesions of the skin, nails or for application to the external genitalia, as well as for the treatment of candidiasis in men. The product is applied up to 3 - 4 times a day in a thin layer.

Possible complications and side effects

Despite the fact that the drug is approved during pregnancy, various adverse reactions and complications may occur when using it.

When taking pimafucin tablets, nausea and loose stools may occur. However, these minor disorders go away on their own with further use of the product.

When using cream and suppositories, burning and minor tissue irritation may occur. Such conditions do not require additional treatment and soon go away on their own.

Pimafucin should not be taken if allergic reactions of any kind (rash, swelling, etc.) have ever been reported to the components of the drug.

It is noteworthy that the drug can be combined with others, since it is not absorbed in the intestines and skin surface, and does not interact with other medications.

Analogs

There are drugs that also contain 100 mg of natamycin and have the same methods, indications and contraindications for use. These include:

  • Natamycin. Its cost varies from 200 to 400 rubles.
  • Primafungin. Price from 220 rubles for three vaginal suppositories.
  • Ecofucin is also only in the form of suppositories.

Thus, there are analogues for this drug, but they are not presented in all forms; only pimafucin has a variety (cream, tablets).

Often during pregnancy one has to deal with manifestations of candidal infection of the genital organs in a woman. The doctor and the expectant mother always face a choice - whether to use an effective or safe medicine.

Pimafucin is a drug that can be safely prescribed even in the early stages of pregnancy and continued until birth if necessary. Baby and mother will be safe using this medicine.

During pregnancy, a woman's immunity tends to decrease. This is provided by nature so that the mother’s body does not reject her fetus as foreign. However, this condition leads to greater susceptibility to various infections. Especially often, expectant mothers are worried about thrush, or candidiasis. Some women first encounter this disease during pregnancy. Therefore, the question often arises of how to treat candidiasis during pregnancy. Pimafucin is often the drug of choice in the treatment of thrush. Let's look at what this medicine is, when it is prescribed and how Pimafucin should be taken during pregnancy.

Use of Pimafucin during pregnancy

Pimafucin is an antifungal drug. Its active substance is natamycin, a polyene antibiotic from the macrolide series, which has a wide range of applications. Providing a fungicidal effect, this substance binds particles of the cell membrane of fungal cells, thus disrupting its integrity and functioning, which contributes to their death.

As indicated in the instructions, Pimafucin is not prohibited for use during pregnancy. This medicine does not have any adverse effects on the baby in the womb. It is practically not absorbed from the surface of the skin and mucous membranes, as well as from the gastrointestinal tract, therefore it does not enter the bloodstream and cannot penetrate the placenta to the child.

Indications for the use of Pimafucin during pregnancy are the following infections caused by fungi of the genus Candida:

  • Vulvitis;
  • Vaginitis;
  • Vulvovaginitis.

Instructions for Pimafucin during pregnancy

This drug is available in three dosage forms - vaginal suppositories, cream and tablets. According to reviews, Pimafucin during pregnancy is most often used in the form of suppositories, although other forms are also sometimes prescribed. In each specific case, the doctor determines the dosage, frequency of administration and duration of treatment with the medicine.

Typically, Pimafucin suppositories are used during pregnancy, 1 pc. once a day at night. The suppository, previously freed from the contour cell, is inserted deep into the vagina in a supine position. The course of treatment is 3-6 days.

In case of severe disease, in addition to suppositories, the doctor may prescribe Pimafucin tablets. As a rule, in this case, take 1 tablet 3-4 times a day. The duration of the course of therapy is 10-20 days.

Pimafucin cream is applied to the affected areas of the mucosa 1-2 times a day. It is usually prescribed as an adjunct to therapy with suppositories or tablets. The duration of treatment is determined by the doctor.

Pimafucin tablets, cream and suppositories during pregnancy can cause side effects in the form of an allergic reaction. Thus, the use of suppositories and cream may be accompanied by swelling of the mucous membrane, a burning sensation and itching at the injection site. Taking Pimafucin tablets sometimes leads to nausea, vomiting and stool disorders. If any of these symptoms occur, you should stop using the medicine and report the problem to your doctor.

The only contraindication to the use of Pimafucin is the increased sensitivity of the body to its components.

Opinions about the effectiveness of Pimafucin differ. This drug is considered a somewhat outdated cure for thrush. As noted in the reviews, Pimafucin does not help all women during pregnancy. Some of them manage to defeat candidiasis, while others do not notice any improvement when taking it. There are also patients who indicate a worsening of their condition when taking Pimafucin. In addition, if most doctors consider this drug absolutely safe for the expectant mother and her fetus, some still do not recommend it to women during this period.

Pimafucin is used during pregnancy due to its lower toxicity compared to other drugs for candidiasis. As already mentioned, when carrying a baby, it is preferable to use suppositories. If after long-term use of the drug there is no improvement, you must inform your doctor, who will select another remedy.

Text: Galina Goncharuk

Pimafucin is one of the most well-known antifungal drugs, widely used in gynecological practice. Pimafucin is available in several dosage forms:

  • suppositories for vaginal use;
  • cream;
  • tablet form.

The mechanism of action of this drug is based on binding to elements of the cell wall membranes of fungal infection pathogens. As a result, destruction of cellular structures occurs, leading to the death of the fungal cell. The peculiarity of Pimafucin is that it acts only locally, that is, locally at the site of its application.
This does not prevent this drug from fighting any localization of the fungal process due to the large number of dosage forms.

Can Pimafucin be used during pregnancy?

The active ingredient Pimafucin is not absorbed into the systemic circulation, so this drug has proven itself in use in pregnant women. The medicine does not affect the fetus, and only a few drugs can boast of this. For a pregnant woman, thrush is a borderline state between normal and pathological - during pregnancy, immunity physiologically decreases, and accordingly, conditionally pathogenic organisms begin to actively multiply.

Indications for use of Pimafucin

Suppositories for thrush during pregnancy Pimafucin are used for fungal infections of the vagina.

Pimafucin cream for women during pregnancy is used for candidiasis of the external genitalia. Pimafucin in the form of a cream helps to cope with candidiasis of the mucous membranes and skin of various locations; otitis externa is also no exception.

The tablet form of Pimafucin successfully copes with candidiasis of the intestines and stomach.

Contraindications to the use of Pimafucin for pregnant women

This drug is absolutely safe when used by a pregnant woman. Pimafucin is often used in the form of suppositories.

The only reason for refusing to use the product, which is justified in the case of a pregnant woman, is an allergic reaction to natamycin.

Pimafucin during pregnancy in the 1st trimester

Pimafucin is used in all trimesters of pregnancy. If candidiasis occurs in the first trimester of pregnancy, then most likely its etiology should be sought before pregnancy. The cause may be chronic diseases, regular stressful situations, or even poor nutrition.

Pimafucin suppositories in early pregnancy are absolutely safe for the fetus. For vulvar candidiasis, you can use Pimafucin cream during pregnancy; how to use it and the frequency of use should be clarified with your doctor.

Pimafucin during pregnancy in the 2nd trimester

In the second trimester, candidiasis during pregnancy occurs as a consequence of a physiological decrease in the woman’s immune status. This is due to quite strong hormonal changes in the body. As a result of these changes, physiological immunosuppression occurs during pregnancy and activation of candida flora. Pimafucin (ointment) during pregnancy is used for candidiasis of the external genitalia, which are often involved in the process of vaginal candidiasis.

Pimafucin during pregnancy in the 3rd trimester

In the third trimester, taking the drug is also not contraindicated, and on the contrary, it is indicated. If childbirth occurs vaginally, it is important that the baby passes through a sanitized vagina, since the flora in the woman's birth canal can pass on to the newborn baby.

Treatment of thrush is necessary at any stage of pregnancy, since long-term untreated candidiasis can lead to serious consequences in the form of infection of the fetus.

How often can Pimafucin be used during pregnancy?

During pregnancy, Pimafucin can be used as many times as the situation requires. However, the appointment should only be made by the attending obstetrician-gynecologist.


Pimafucin during pregnancy: instructions for use

During pregnancy, doctors recommend using one vaginal suppository at night for about 10 days, depending on the severity of the clinical manifestations of the disease.

The procedure for using other forms of Pimafucin is determined individually by a gynecologist.

Discharge after Pimafucin during pregnancy

Discharge after Pimafucin acquires its normal character - this is the average volume of physiological leucorrhoea without an admixture of a cheesy nature.

Pimafucin analogues approved during pregnancy

You can also use an analogue of Pimafucin suppositories for thrush during pregnancy. These include Ecofucin and Primafungin. Distinctive features are only the country of origin of the drug:

  • Pimafucin is produced in Denmark;
  • Primafungin - in Russia;
  • Ecofucin - in Russia.

The price of drugs also varies, Pimafucin is a more expensive foreign drug. In reviews, women note that they do not see much difference in the therapeutic effect - all three drugs are quite effective.