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How to take furadonin for pregnant women. Is it possible to drink Furadonin during pregnancy? While carrying a baby

The fact that cystitis and pyelonephritis have become a frequent occurrence, and even a mandatory accompaniment of every fourth pregnancy, no longer surprises not only doctors, but also expectant mothers themselves. During courses for pregnant women and during medical consultations, they receive enough information about what causes infectious diseases during pregnancy.

The question is different: how to get rid of obsessive diseases without risks to the fetus. After all, what was permitted in the pre-pregnancy state is, as a rule, prohibited during pregnancy. We are talking about effective drugs, the effect of which on the fetus can be reflected in the most negative way.

One of these is nitrofuran Furadonin, which has a wide range of effects on bacterial flora and is able to penetrate the placental barrier.

Toxicity of Furadonin: fact or fiction?

Doctors are afraid to prescribe the drug Furadonin to pregnant women, since it has the ability to have a toxic effect on the fetus. And, nevertheless, this medicine cannot be classified as too toxic.

Of course, Furadonin contains a certain level of toxins, but scientists have not yet been able to draw a final conclusion.

Thus, the drug belongs to group B in terms of the degree of impact on the fetus, which means: in experimental studies on pregnant animals, harm to the fetus was detected, but during clinical use it was not detected or has not been sufficiently studied.

Each manufacturer of Furadonin in the annotation for the drug indicates that it is undesirable or prohibited to take the drug during pregnancy, since the risk of toxic effects on the fetus is still present. Theoretically, the drug may have no effect, but since the drug belongs to category B, it makes sense to warn patients about the potential danger.

In practice, Furadonin is prescribed to pregnant women, but not immediately after diagnosing a certain disease, but after careful research. During the research stage, a pregnant woman must undergo a urine test (bacteria culture) in order to identify the causative agent of the infection and its sensitivity to the drug.

What is the secret of the effectiveness of Furadonin?

Many experts emphasize that Furadonin, although not a representative of the newest generation of antibacterial drugs, remains traditionally effective and is used in cases where other drugs are powerless in the fight against infections of the genitourinary system.

Why are other effective drugs developed using the latest technologies inferior to Furadonin? There is a term “microflora insensitivity”, which means the lack of reaction of pathogenic microorganisms to the components of an antibacterial agent. For example, you purchased a very potent medicine, and with its help you were able to suppress the infection in a matter of days. In case of relapse, the same medicine will help much more slowly. And with repeated courses of treatment for the same type of infection, it will act very badly. It all depends on how the pathogens become accustomed to the drug (they also know how to develop immunity).

In the case of Furadonin, the adaptation of pathogenic bacteria to its components occurs very slowly, so the drug does not lose its effectiveness.

Composition and pharmacokinetics

The active substance of the drug is nitrofurantoin.

Additional components:

calcium stearate;
colloidal silicon dioxide;
potato starch.

The drug has a high antimicrobial effect, but does not belong to the group of antibiotics, as many patients mistakenly believe. However, during pregnancy it must be used with great caution.

When the active substance enters the gastrointestinal tract, it is actively absorbed from it and is 60% bound to plasma proteins. Metabolic processes occur in the liver, as well as in muscle tissue, the drug is excreted by the kidneys, with 30-35% leaving the body unchanged.

The active substance overcomes the placental barrier and penetrates into breast milk.

Indications

Indications for the use of Furadonin during pregnancy may include:

pyelonephritis;
cystitis;
urethritis;
pyelitis;
infectious and inflammatory processes of the urinary tract, provoked by pathogenic bacteria sensitive to the drug.

Contraindications and side effects

In the instructions for the drug, pregnancy is designated as a contraindication, but doctors consider it, rather, as a warning about caution in the use of Furadonin: the medicine can be prescribed, but not in the usual, but in a significantly reduced dosage.

The drug is not prescribed if the patient has impaired renal or liver function, has been diagnosed with one of the cardiovascular diseases, or acute enzymatic deficiency.

During the period of use of Furadonin, side effects are possible in the form of:

cough, shortness of breath, toxic damage to lung tissue;
loss of appetite, nausea, vomiting;
headache, dizziness, lethargy;
allergic skin rashes;
increase in body temperature.

Furadonin by trimester

1st trimester

In the first weeks of the birth of a new life, the first and second remain absolutely safe for the embryo in terms of the mother taking medications, including Furadonin, when the embryo is not yet connected to the mother’s body and develops autonomously, receiving everything it needs from the fertilized egg.

But from the third to the twelfth week inclusive, the fetus becomes very vulnerable to the effects of Furadonin components, so the use of the drug during this period is prohibited.

2nd trimester

After the 12th week of pregnancy, the drug is prescribed only after laboratory tests and examination of the patient’s clinical picture. The appointment is made by the attending physician, weighing the benefits of the drug for the health of the mother.

3rd trimester

The prescription is carried out only in case of urgent need and if there is no alternative among other medicines.

For pregnant women, antimicrobial agents to relieve inflammation are prescribed quite often. The percentage of expectant mothers who come in with cystitis, pyelonephritis, pyelitis and other infectious processes in the urinary tract is more than 40%.

This issue becomes relevant due to surges in hormone levels, a decrease in general immunity, and pressure from the growing uterus on the bladder, which provokes the accumulation and stagnation of urine with its further infection. If the identified causative agent of the disease is sensitive to Furadonin, it is prescribed, despite the fact that pregnancy is included in the list of contraindications to it, why is this?

This is a synthetic drug with an antimicrobial effect, based on nitrofurantoin.

Metabolism of this medicine occurs in the intestines, and not in the liver, like most antibiotics.

From the intestines, the lymph current spreads throughout the body and blocks the spread of infection.

The main substance accumulates in the urine, thanks to which it is effective against diseases of the bladder, ureters and kidneys, and after 3-4 hours it is already excreted from the body.

The ban is based on the fact that the active substance is able to overcome the placental barrier and negatively affect the growth and development of the fetus, which is fundamental and intense during this period.

Indications for the use of Furadonin during pregnancy should be based on the result of bacterial culture, which showed that the pathogens are sensitive to it. Taking a drug without a test result is risking your health and that of your child.

Development of hemolytic anemia: destruction of red blood cells that provide oxygen delivery to internal organs. This is an extremely dangerous condition, since the tissues are not only not supplied with oxygen, but are also subject to destruction by indirect bilirubin, released in huge quantities during the destruction of red blood cells.
Disorders of intrauterine development: disproportion of body parts, defects of internal organs

From the respiratory system: compressive pain in the chest, shortness of breath, attacks of bronchial asthma in the presence of the disease.
From the digestive system: lack of appetite, vomiting, attacks of nausea, diarrhea. In cases of weakened liver, hepatitis may develop.
From the nervous system: headaches, lethargy, feeling tired.
From the hematopoietic system: a decrease in the number of leukocytes, leading to weakened immunity, platelets, reducing blood clotting, the development of anemia.
Allergies: Quincke's edema, skin rash.
Other: fever, joint aches, flu-like.

Take Furadonin as prescribed by a doctor, based on an analysis of pathological flora.
Take each dose of medication with a glass of clean water.
Do not delay emptying your bladder.
Take a repeat flora test after 3 days of taking the medicine; if it shows that acute inflammation has been relieved, switch to herbal remedies or homeopathic remedies. After consultation with your doctor!
Use the drug only after 12 weeks of pregnancy.

In cases of ineffectiveness of the drug, most likely, it is taken at random, without analysis or medical prescription.

Those who found the drug useful note its rapid action - after 3 days there was a significant improvement, no side effects.

Those who were helped by Furadonin over a longer period - 7 days - noted nausea, vomiting, pain and aching joints similar to a flu-like condition.

The drug has a relatively low cost and acts more mildly than its domestic analogue Furagin.

Although it is not advisable to take any medications during pregnancy, there are situations when it becomes necessary. Cyston during pregnancy: indications for use, as well as reviews of women about treatment.

Read about how to relieve pain from cystitis here.

And here https://mkb2.ru/tsistit-i-mochevoy-puzyir/u-zhenshhin/tabletki-ot-cistita.html all about the treatment of cystitis in women with the help of medications. The effect of drugs on the body.

Furadonin is far from the most toxic drug in terms of its effects on the liver and kidneys.

Its effects on fertility (the ability to reproduce) have only been studied in animals and indicate a potential risk to the fetus.

Clinical studies (taken by pregnant women) have not confirmed this risk, but since it was initially identified, the drug is included in list B and is contraindicated during pregnancy.

Domestic medical practice does not know of cases of direct negative effects on the fetus and the occurrence of malformations after taking Furadonin, so it is often prescribed by doctors.

Start treatment with a test, take the medicine if prescribed by the doctor, follow the rules of administration and inflammatory diseases will recede without causing harm to you and your unborn child!

Due to hormonal changes in a pregnant woman, her body becomes more susceptible to certain diseases. Cystitis during pregnancy: symptoms of acute and chronic inflammation, laboratory diagnosis of the disease.

Read about the features of selecting drugs for the treatment of cystitis in women in this material.

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During the period of gestation, a woman’s immunity and her body are weakened - this creates a favorable environment for infection by all kinds of diseases. But since this or that medication should be taken with caution during pregnancy, it is important to understand whether Furadonin can be taken, what restrictions and indications there are.

The instructions attached to Furadonin prescribe that this drug is classified as a group of medications with pronounced antibacterial and bactericidal properties. Moreover, the drug itself is not an antibiotic in the usual sense; it belongs to the group of nitrofurans.

Active ingredient - nitrofurantoin, they produce it in the format of tablets containing 100 or 50 mg of the active substance, enteric-coated. Mostly used to treat urinary tract and bladder infections. Moreover, for such a disease as cystitis, it is practically not prescribed due to its side effects. But in any case, its purpose, dosage and course of treatment should be determined by a doctor.

The presented drug belongs to the group nitrofurans- compositions with a pronounced antimicrobial, suppressive effect on pathogenic microorganisms that affect the genitourinary system. Today, the range of antibacterial compounds is large, but doctors most often prescribe this particular drug. This prescription is due to the fact that if the pathogenic microflora is not sensitive to other antibiotics, it is effectively suppressed by this medicine.

It is enough to note that group B drugs are most often prescribed to expectant mothers and women during lactation - and during this period there are limitations and indications, rules and dosages of administration. This drug is prescribed exclusively by a doctor, after a microbiological study.- most often this is urine culture, which will allow us to determine the causative agent of the pathological process and the level of its sensitivity to the active components of the medicinal composition.

Regarding the method of use of the drug and dosage, take Furadonin orally with a sufficient amount of water. The dosage of the drug per day is 0.1 - 0.15 g 3-4 times a day, depending on the degree of the disease. The maximum permissible daily dosage of the drug should not exceed 0.6 mg, while a single dosage should not exceed 0.3 mg. The duration of the course of treatment is 7−10 days, subject to the acute form of the infectious process, the doctor can increase the duration of the course to 2 weeks.

Regarding the indications for taking Furadonin during pregnancy, doctors and manufacturers highlight the following points:

As the main drug for the treatment of infectious and inflammatory nature of the origin of pathology affecting the urinary tract, suppression of pathogenic microflora sensitive to the active components of Furadonin - pyelitis and urethritis.
For the prevention and prevention of recurrence of infectious pathologies during operations on the genitourinary system, as well as cystoscopy and catheter placement.

Most often, this drug is prescribed if bacteria and pathogenic fungi that provoke inflammation cannot be effectively treated with less toxic medications.

Regarding existing contraindications, developers and doctors name the following points and restrictions:

A pronounced malfunction of the liver and kidneys.
When diagnosing congenital G6PD deficiency in a patient.
During severe forms of the cardiovascular system.
Doctors also call individual intolerance and hypersensitivity to the medicinal composition and active ingredients a limitation to the prescription.

Regarding overdose, the latter manifests itself with dizziness and nausea, bouts of vomiting and diarrhea. In terms of treatment of overdose, this means stopping the drug and consuming large amounts of fluid, conducting a course of hemodialysis and symptomatic treatment. As for the antidote, there is no such thing.

Instructions for using Canephron can be found in this article.

Regarding the side effects of taking Furadonin during pregnancy, these may be:

Respiratory system - side effects show themselves as coughing attacks and pain in the sternum, shortness of breath and pulmonary edema, less often - a deterioration in the general condition of all those who suffer from bronchial asthma.
The gastrointestinal tract may show loss of appetite and vomiting, attacks of nausea and diarrhea, less often the liver is affected, after which hepatitis develops.
From the side of the central nervous system - attacks of dizziness and migraines, general weakness also shows itself.
Anemia develops and the total number of leukocytes decreases, and bleeding may increase.
Allergic skin rashes, urticaria and itching also show themselves, with more serious intoxication of the body - anaphylactic edema of the larynx.
Doctors include other negative consequences and side effects from taking the drug: increased body temperature, pain in the joints, when bones ache like a cold.

To avoid negative consequences, you should not practice self-medication.

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During pregnancy, the urinary tract often becomes inflamed. This is due to the weakening of the body, as well as the increase in the size of the uterus, which constantly puts pressure on the pelvic organs. The close location of the urinary canal to the vagina and its openness often contribute to frequent inflammatory processes.

Furadonin is indicated for the treatment of infectious diseases of the genitourinary system, as well as various inflammations during pregnancy in women. However, such measures are resorted to only in situations where other drugs with less toxicity are not able to cope with the task.

This drug is an antimicrobial agent based on nitrofurantoin. According to the degree of influence on the fetus, the medicinal substance is classified as group B. This means that the active substances pass through the placenta and reach the fetus in the womb. However, the tests were carried out on animals and have not been fully studied.

Furadonin during pregnancy is prescribed only if the microflora is insensitive to other antibacterial medications. While the adaptation of pathogens to Furadonin occurs extremely slowly, which ensures a high result in treatment.

The basis for prescribing this medication should be the results of bacterial culture showing the sensitivity of the pathogen to Furadonin. Mainly used for:

Taking the drug is contraindicated if you have:

disorders of the kidneys and liver;
congenital deficiency of glucose-6-phosphate dehydrogenase;
diseases of the cardiovascular system;
high sensitivity to its components.

The use of Furadonin can cause the following adverse reactions:

respiratory system - cough, pain in the sternum, shortness of breath and possible pulmonary edema; patients suffering from bronchial asthma may experience an increase in attacks;
Gastrointestinal tract - possible vomiting and nausea, lack of appetite. In some situations, pain in the upper abdomen and diarrhea occur. Toxic liver damage and subsequent development of hepatitis are possible;
in the circulatory system – a decrease in the number of leukocytes is possible, as a result of which immunity decreases. If the platelet count decreases, the risk of bleeding and anemia will increase;
dizziness and headaches, neuritis;
allergic reactions manifest themselves in the form of urticaria or angioedema;
increase in temperature accompanied by joint pain.

violation of intrauterine development: defects of internal organs, disproportion of body parts;
red blood cells that deliver oxygen to internal organs are destroyed.

only during meals or immediately after;
Additionally, take the drug with plenty of fluids;
do not delay the release of the bladder;
re-take flora tests every 3 days and as soon as acute inflammation is relieved, urgently switch to herbal medicines.

From the first days to the twelfth week, the embryo is most sensitive to any external influences. Even more so with medications. In the early stages, the formation of its most important organs and tissues occurs. After being introduced into the body of the uterus on the seventh day, the embryo and mother have a common circulatory system, so any drugs penetrate simultaneously to the fetus.

The use of an antimicrobial drug is fraught with serious disruptions in the development of the embryo, including termination of pregnancy. Fetal defects, such as improper closure of the neural tube, may occur.

Furadonin is officially prohibited for use in the third trimester of pregnancy. This is due to a significant toxic effect on the child’s circulatory system. The use of the drug can provoke hemolytic anemia. In the future, this will manifest itself in the form of jaundice, hypoxia and a number of other complications.

Prescribing the drug in later stages is extremely rare. Only if the pathogen is capable of harming the mother and child even more than the medicine.

Due to its highly targeted action, the drug is much more effective than its analogues. You should not start taking the medicine on your own. Only after a full examination will a specialist be able to determine whether Furadonin can be taken.

And if, nevertheless, the doctor decides to treat a pregnant woman with Furadonin, then monitoring the condition of her blood will be required every 7 days.

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An effective drug for the treatment of bladder inflammation is Furadonin. For cystitis, it stops the proliferation of bacteria and speeds up recovery.

Cystitis is one of the most common diseases of the genitourinary system among women. According to medical statistics, about 80% of cases occur in females. The painful condition occurs due to many pathological reasons that lead to inflammation of the mucous membrane of the bladder.

Treatment depends on a number of factors, which are classified according to the following criteria:

Type of pathogen: bacterial (chlamydia, ureaplasma, gonorrhea, staphylococci, streptococci and others) and non-bacterial (toxic, medicinal, allergenic).
Nature of the course: acute and chronic.
Morphological changes in the organ: ulcerative, catarrhal, cystic.
Localization of pathology: mucous membrane of the bladder, submucosal layer, muscle layer.

Treatment is carried out by several specialists at the same time: a urologist, a nephrologist and a gynecologist. With a properly selected therapy regimen, recovery occurs within 7-12 days. Most often, the disease develops due to the action of pathogenic microorganisms. To destroy them, specific therapy is carried out with antibacterial and antimicrobial drugs.

Furadonin is an antimicrobial agent from the pharmacological group of nitrofurans. Each tablet contains 50/100 mg of the active ingredient nitrofurantoin. The active component disrupts the permeability of cell membranes and protein synthesis in bacterial cells. Has bacteriostatic and bactericidal effects.

The drug exhibits high activity against gram-negative and gram-positive bacteria. It is most effective against the following pathogens: Streptococcus spp., Staphylococcus spp., Salmonella paratyphi A, Salmonella typhi, Salmonella paratyphi B, Escherichia coli, Enterobacter spp., Proteus, Shigella sonnei. The drug is available over-the-counter, but should be taken only in consultation with your doctor.

Cystitis is an unpleasant disease that affects both women and men. It is manifested by discomfort in the lower abdomen, painful urination and a burning sensation in the genitals. It is better to treat the disease in the early stages, since as the inflammation progresses, it becomes chronic.

The choice of treatment method depends on the cause of the disease: infection, hypothermia, fungal infection. To select an effective drug and determine the cause of the disorder, a urine test is indicated.

If inflammation is caused by infection, then antimicrobial and antibiotic agents are indicated. Furadonin is one of the most effective drugs for the rapid treatment of cystitis. The medicine not only fights the infection, but also stops the inflammatory process. Has a wide spectrum of antimicrobial action. It is used only for medical prescription, as it can cause adverse reactions and has contraindications.

Furadonin is an antimicrobial agent from the pharmacological group of nitrofurans. The main indications for its use are infectious and inflammatory diseases of the urinary tract caused by drug-sensitive microorganisms:

The drug is also used as a prophylactic agent during urological operations, cytoscopy, and catheterization.

Very often, inflammation of the bladder occurs in an acute form. The unpleasant condition is manifested by frequent and painful urination, the presence of pus and blood in the urine, and low-grade body temperature.

Treatment must be comprehensive. Furadonin for acute cystitis is prescribed with systemic anti-inflammatory, diuretic and antibacterial drugs. The action of the medication is aimed at destroying pathogens and reducing inflammation. Interaction with other drugs provides a lasting therapeutic effect over a short period of time. The average course of treatment is 5-7 days.

The drug is intended for oral use and has two release forms:

Enteric-coated tablets in packages of 12, 20, 30, 40 and 50 pieces.
Suspension with a measuring cup or spoon.

The choice of release form depends on the age of the patient and the duration of the planned therapy.

A mandatory component of the treatment of bladder inflammation is drug therapy. If the disease is associated with infectious factors, then antibacterial and antimicrobial tablets for cystitis are prescribed. Furadonin is the last.

The drug has a wide spectrum of action and belongs to the group of nitrofurans. Stops the proliferation of microbes and destroys them. Used for urinary tract infections.

The tablets are enteric-coated, so after oral administration they are well absorbed from the gastrointestinal tract. The active ingredients penetrate the placenta, into the cerebrospinal fluid and breast milk, so the drug has restrictions on use during pregnancy and for pediatric patients.

Avexima, a full-cycle pharmaceutical company, is engaged in the development and production of medical devices, substances and medications of various spectrums of action. The company produces more than 30 types of finished dosage forms, including Furadonin Avexima.

An antimicrobial agent used to treat urinary tract infections. It is active against gram-positive and gram-negative microorganisms. Well absorbed from the gastrointestinal tract, bioavailability is about 50%, binding to plasma proteins is 60%. Metabolized in the liver and muscle tissue, completely excreted by the kidneys.

Indications for use: bacterial urinary tract infections, prevention of infections during urological operations and diagnostic procedures.
Directions for use and dosage: orally with plenty of liquid. Adults: 100-150 mg 3-4 times a day. The dose for children is 5-8 mg/kg, divided into 4 doses per day. The maximum single dose is 300 mg, the maximum daily dose is 600 mg. The duration of treatment for acute infections is 7-10 days.
Side effects: nausea, vomiting, allergic reactions, increased drowsiness, dizziness and headaches, cough and more.
Contraindications: hypersensitivity to the components of the drug, chronic renal failure, liver cirrhosis, acute porphyria, heart failure grade 2-3, age under 3 years, pregnancy and lactation.
Overdose: nausea and vomiting, allergic reactions. For treatment, it is recommended to take a large amount of fluid to remove the drug as quickly as possible.

Furadonin Avexima is an over-the-counter medication, but it should be used as prescribed by a doctor.

A drug from the nitrofuran group with antimicrobial properties. It disrupts the permeability of cell membranes and protein synthesis in bacteria. Has bacteriostatic and bactericidal effects.

Highly active against gram-negative and gram-positive microorganisms, especially Streptococcus spp., Staphylococcus spp., Salmonella paratyphi A, Salmonella typhi, Salmonella paratyphi B, Escherichia coli, Enterobacter spp., Proteus, Shigella sonnei.

The active substance is nitrofurantoin, belongs to the nitrofuran group, a uroantiseptic. Creates increased concentrations in urine, which is especially effective for lesions of the urinary tract.

According to reviews of many patients who were prescribed Furadonin for cystitis, the therapeutic effect appears 3-4 hours after taking it. The active components act only on the excretory system, without affecting the intestines and other organs. This reduces inflammation and other painful symptoms.

The medicine has a wide spectrum of antimicrobial action. To completely destroy the infection, the drug must be taken for 5-7 days. If the tablets are used for prophylactic purposes, take 1 capsule before bedtime for 3 days.

After oral administration, nitrofurantoin is rapidly absorbed into the gastrointestinal tract. Bioavailability is about 50%; food intake increases this value. Binding to plasma proteins is 60-95%. The active components are partially metabolized in the liver. About 30% is excreted unchanged in the urine, since the drug has a bacteriostatic and bactericidal effect on the urinary tract.

Therapeutic concentrations in tissues and blood do not occur. The half-life is about 60 minutes. High levels of nitrofurantoin in urine persist for 12 hours. The components of the drug penetrate the placental and blood-brain barrier, as well as into breast milk.

The use of nitrofuran derivatives is contraindicated for the treatment of pregnant women in the early stages of pregnancy. Despite the fact that Furadonin is a drug with low toxicity, its active substance penetrates the placental barrier and can have a toxic effect on the fetus. This is dangerous due to intrauterine mutations and other developmental disorders of the fetus.

The drug is approved from the second trimester and in very small doses - 0.1-0.5 mg 3-4 times a day. When using the medication during lactation, breastfeeding should be stopped, since the active substances penetrate into mother's milk. The decision on the advisability of using an antimicrobial agent should be made by the attending physician, taking into account the expected therapeutic effect for the woman and the risks for the child.

Furadonin is prohibited from use in case of individual intolerance to its active components and other nitrofurans. The drug is also contraindicated in the following cases:

Chronic renal failure.
Chronic heart failure II-III degree.
Cirrhosis.
Chronic hepatitis.
Acute porphyria.
Glucose-6-phosphate dehydrogenase deficiency.
Pulmonary fibrosis.
Pyelonephritis.
Oliguria.
Anuria.
Chronic hepatitis.
Neuritis and polyneuropathy.

The drug is not used for treatment during pregnancy and lactation. Also prohibited for hemodialysis patients and children under 1 month of age.

Gastrointestinal tract: nausea, vomiting, loss of appetite, abdominal pain, diarrhea.
Nervous system: headaches, dizziness, drowsiness, increased intracranial pressure.
Immune system: hypersensitivity reactions and autoimmune reactions.
Respiratory system: chest pain, shortness of breath, fever.
Liver and biliary tract: cholestatic jaundice, hepatitis.
Skin and blood vessels: hyperemia, rashes, itching, angioedema, inflammation of the salivary glands.
Hematopoietic and lymphatic systems: leukopenia, thrombocytopenia, hemolytic anemia.

Most often, side effects develop when the dosage and duration of therapy are not observed. The appearance of the above symptoms requires medical consultation and temporary refusal to take pills.

The drug is taken orally during or after meals with plenty of water. The dosage depends on the characteristics of the course of cystitis. For adults and patients over 12 years of age, the following doses are recommended:

Acute infections: 100 mg 2 times a day for a week.
Severe chronic recurrent infections: 100 mg 3-4 times a day for 7 days.
Prevention of infections during surgical interventions and diagnostic procedures: 100 mg 2 times a day of the procedure and 3 days after.

The dosage for children under 12 years of age is 5-8 mg/kg per day, divided into 4 doses. The maximum single dose is 300 mg, daily dose is 600 mg. The duration of treatment depends on the severity of the painful condition.

The treatment regimen is selected individually for each patient. According to the instructions for use, Furadonin should be taken 1-2 tablets (100-150 mg) 3-4 times a day. Duration of therapy is 5-10 days. Moreover, the earlier treatment is started, the higher the therapeutic effect. Many patients note relief from the painful condition within 2-3 days. Despite the positive results, treatment cannot be stopped, as the disease can recur or become chronic.

When using a drug, a number of features of antimicrobial therapy should be taken into account:

The drug is prescribed with caution for patients with impaired renal function. Reduced excretion of the active substance and a violation of its concentration in urine can increase the level of nitrofurantoin in the blood plasma. This is dangerous due to intoxication of the body.
Use with caution to treat patients with anemia, endocrine diseases, imbalance of electrolytes and B vitamins, lung diseases, and general exhaustion of the body.
With long-term treatment, it is necessary to monitor respiratory functions, especially in elderly patients, as there is a risk of worsening pulmonary reactions.
During long-term therapy, liver function indicators and blood counts should be monitored. There is a risk of developing chronic hepatitis and cholestatic jaundice.
The medication disrupts the normal microflora of the colon, so it can cause diarrhea caused by Clostridium difficile.
In rare cases, long-term therapy leads to bacterial resistance. To normalize the condition, you should stop taking the drug and choose another antibacterial agent.

Furadonin does not affect psychomotor reactions when working with machinery or while driving vehicles.

In order for an antimicrobial agent to have the maximum healing effect without harm to the body, it is necessary to correctly select the dosage and duration of therapy. If cystitis occurs without complications, then the following treatment regimen is indicated:

Children under 12 years of age – 5-8 mg/kg per day. The dose is divided into 4 doses.
Patients over 12 years of age - 100 mg 2-3 times a day.
Persons over 16 years old - 100 mg 4 times a day for 7 days.

On average, tablets are taken for 5 to 10 days. If the medicine is used for preventive purposes, it can be a single dose of 100 mg or longer therapy.

When using Furadonin, it is important to take it correctly. Tablets are taken during or immediately after meals. Do not chew the capsules and take them with plenty of water. If the next dose was missed, then the next one goes without changing the dosage. In most patients, relief of the painful condition is observed after 2-3 days of treatment.

When treating infectious inflammation of the bladder, special attention is paid to preventive measures. To prevent exacerbations of cystitis, a maintenance dose of Furadonin is recommended - 50-100 mg once a day, preferably before bedtime.

The duration of such therapy is determined by the doctor. As a rule, prevention lasts from 3 to 12 months. In addition to drug therapy, it is important to observe basic rules of personal hygiene and adhere to a gentle diet. This can significantly reduce the risk of recurrent infection.

Bladder inflammation is most often diagnosed in women. The prevalence of cystitis is explained by their anatomical features. Women's urinary tracts are shorter than men's, and the opening of the canal is close to the anus, which allows bacteria to enter the urethra. The disease is also closely related to hormonal changes in the female body.

Anti-inflammatory, antibacterial and other drugs are used for treatment. If the inflammation is caused by an infection, then antimicrobial agents are used. Furadonin belongs to this category of drugs. It has bacteriostatic and bactericidal properties. Effective for acute and chronic cystitis. As a rule, women are prescribed 100-150 mg 3-4 times a day for 5-7 days. The medicine can also be used to prevent inflammation.

The prevalence of cystitis among men is much lower than among women. Patients over 40 years of age are more likely to experience bladder inflammation. The disease can be caused by urological problems, that is, develop after suffering inflammatory or infectious diseases.

Taking medications is a mandatory component of therapy and is practically no different from treatment for women. Furadonin is effective for cystitis caused by pathogens: gram-positive and gram-negative aerobic bacteria.

The tablets are taken orally. The dosage and duration of treatment depends on the characteristics of the disease. If the inflammation is uncomplicated, then prescribe 100-150 mg 3-4 times a day for 5-10 days. Relief of the painful condition is observed on days 2-3 of treatment.

Treatment of cystitis in pediatric practice has a number of difficulties, since many effective drugs are contraindicated. As for Furadonin, its use for children under 12 years of age must be justified by strict indications. The drug is prohibited for babies under 1 month of age.

The dosage for patients under 12 years of age is calculated at 5-7 mg/kg per day. The daily dose is divided into 4 equal doses. For children over 12 years old – 100 mg 2-3 times a day. Duration of treatment is 5-7 days.

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The site provides reference information for informational purposes only. Diagnosis and treatment of diseases must be carried out under the supervision of a specialist. All drugs have contraindications. Consultation with a specialist is required!

Furadonin– an antimicrobial synthetic medicinal agent with a wide spectrum of action.

Furadonin is not an antibiotic; it belongs to the group of drugs of the nitrofuran series. On many bacteria - Klebsiella, Staphylococcus, Enterococcus, Escherichia coli, Proteus, Enterobacter, etc. - the drug has a bacteriostatic (stops the proliferation of microbes) and bactericidal (kills microbes) effect.

Furadonin is used to treat urinary tract infections.

The drug is well absorbed from the gastrointestinal tract, penetrates the placenta and into breast milk, cerebrospinal fluid, and is excreted by the kidneys. May give urine a dark color. Blood concentrations at usual therapeutic doses are insignificant.

The active substance of the drug is nitrofurantoin.

Tablets 0.05 g, 20 pieces per package.
Tablets 0.1 g, 20 pieces per package.
Tablets 0.03 g, soluble in the intestines, 30 pieces per package (for children).
Furadonin suspension (a measuring cup or spoon is included in the package for dosing).

Individual intolerance to nitrofurantoin;
renal failure with severe impairment of renal excretory function;
chronic active hepatitis or cirrhosis of the liver;
heart failure degree II-III;
deficiency of B vitamins;
genetic (congenital) deficiency of the enzyme glucose-6-phosphate dehydrogenase;
pregnancy and breastfeeding;
early childhood: up to 1 month;
acute porphyria (hereditary disease affecting the nervous system);
purulent inflammation of the perinephric tissue.

Furadonin has a bitter taste. The tablets should not be chewed; You need to wash them down with plenty of water (at least 1 glass).

The bottle of suspension should be shaken well before use, then the required dose of the medicine should be measured. The suspension can be mixed with milk, water or fruit juice.

Taking Furadonin with food or milk can reduce discomfort in the stomach and intestines.

The effect of Furadonin is enhanced in an acidic environment, so it is recommended to consume protein foods in the diet.

During treatment with Furadonin, you should not take nalidixic acid and antacids (drugs that reduce the acidity of gastric juice), which contain magnesium trisilicate, because at the same time, the absorption of Furadonin and its therapeutic effect are reduced.

It is also undesirable to use Sulfinpyrazone and Probenecid at the same time - they help reduce the excretion of Furadonin in the urine. And this will cause an increase in the concentration of Furadonin in the blood, increasing its toxicity and reducing the therapeutic effect in the urinary tract.

Furadonin dosage
The dose of Furadonin is determined by the doctor. Adults are usually prescribed 50-100 mg 4 times a day. The course of treatment lasts 5-8 days; if necessary, the doctor can extend the course of treatment up to 10 days.

In the absence of a therapeutic effect, longer use of the drug is not advisable.

Preventive, anti-relapse treatment can last 3-12 months. The daily dose is determined at the rate of 1-2 mg per 1 kg of patient weight. A prophylactic dose can be taken 1 time per day, before bedtime.

In pediatrics, for the treatment of urinary tract infections, Furadonin can be prescribed to children older than 1 month of life.

The dose of the drug is determined at the rate of 5-7 mg per 1 kg of body weight per day. The daily dose is divided into 4 doses.

Children over 12 years of age are prescribed 100 mg 2 times a day. The course of treatment is 5-7 days.

Experimental studies in animals have shown a risk to the fetus. Clinical experience with the use of Furadonin during pregnancy has not been studied.

Gynecologists sometimes use Furadonin in the treatment of urinary tract infections in women after 12 weeks of pregnancy. In this case, it is necessary to compare the possible risk to the fetus and the therapeutic effect of using Furadonin.

Furadonin is used to treat acute and chronic cystitis (inflammation of the bladder) in both adults and children (over 1 month).

It is advisable to conduct a bacteriological examination of urine (urine culture) before starting treatment to identify the pathogen that caused cystitis and determine the sensitivity of the isolated microorganism to antibacterial agents (including Furadonin). In case of chronic cystitis, such an examination must be carried out at every exacerbation, because both the causative agent of the inflammatory process and its sensitivity to antibacterial agents may change.

The dosage of Furadonin for cystitis is usual: 50-100 mg 4 times a day. Duration of treatment is 7-10 days. Children are prescribed a dose of 5-8 mg per 1 kg of body weight.

Maintenance dose (or prophylactic to prevent exacerbations) for chronic cystitis – 50-100 mg of Furadonin 1 time per day (can be taken at night). The duration of maintenance therapy is determined by the doctor. Treatment can be carried out for 3-12 months.
More about cystitis

Furadonin has no structural analogues (synonyms).

Analogues according to the mechanism of therapeutic action (nitrofuran derivatives):

Furamag;
Furazidine;
Furagin;
Furasol.

Furadonin and Furagin are antimicrobial drugs from the same group (nitrofuran derivatives). The mechanism of action and indications for these drugs are similar. In some cases, Furagin exhibits a more effective effect.

Both of these drugs have almost the same side effects. But in Furagin they are somewhat less pronounced; it is a milder drug in comparison with Furadonin.

Currently, more modern drugs (Norbactin, Nolitsin, etc.) are used in the treatment of urinary tract infections. In any case, the choice of medication is made by the doctor.
More information about the drug Furagin

Among the advantages of the drug, the relative cheapness of Furadonin is noted.

Almost all reviews note the presence of painful side effects, especially from the digestive system (nausea, vomiting, loss of appetite, abdominal pain) and the nervous system (headache, dizziness).

Furadonin tablets 50 mg - the price ranges from 33 to 75 rubles.

Furadonin tablets 100 mg - price from 85 to 108 rubles.

The pregnancy period is a time of exacerbation of a variety of diseases, including infectious ones, such as cystitis.

This is due to the fact that women in this position have a significantly reduced immunity, and the uterus puts very strong pressure on the bladder.

When prescribing medications, the doctor focuses on possible risks for the woman and fetus. In some cases, antibiotic therapy cannot be avoided, so it is often prescribed during pregnancy to treat diseases of the genitourinary system.

The active ingredient of Furadonin is nitrofurantoin. This drug belongs to the group of nitrofurans, synthetic antibacterial drugs. They replaced sulfonamides, the first antiseptics.

Drug Furadonin

Metabolism of this medicine occurs in the intestines, and not in the liver, like most antibiotics. From the intestines, the lymph current spreads throughout the body and blocks the spread of infection.

The main substance accumulates in the urine, thanks to which it is effective against diseases of the bladder, ureters and kidneys, and after 3-4 hours it is already excreted from the body. The fact that this medicine has a spectrum of action that is not inferior to that of antibiotics, with fewer side effects, makes its use more preferable for pregnant women.

Furadonin has another undeniable advantage - bacteria practically do not become addicted to it.

Indications for use

Furadonin is prescribed for:

urethritis;
intestinal diseases.

The drug is used only after confirmation of the sensitivity of microorganisms to it.

If you carefully study the instructions, it follows that pregnancy and lactation are on the list of contraindications to the use of the medicine. Why is this particular medicine often prescribed by doctors for cystitis in pregnant women?

Contraindications for use

Furadonin during pregnancy is allowed for the treatment of cystitis or pyelonephritis, but only in exceptional cases and strictly prescribed by the attending physician.

Possible risks and complications

Harm to the fetus when taking the medicine:

development of hemolytic anemia: destruction of red blood cells that provide oxygen delivery to internal organs. This is an extremely dangerous condition, since the tissues are not only not supplied with oxygen, but are also subject to destruction by indirect bilirubin, released in huge quantities during the destruction of red blood cells;
disturbance of intrauterine development: disproportion of body parts, defects of internal organs.

Harm when taking the medicine for the mother:

from the nervous system: headaches, lethargy, feeling tired;
from the respiratory system: compressive pain in the chest, shortness of breath, attacks of bronchial asthma in the presence of the disease;
from the digestive system: lack of appetite, vomiting, attacks of nausea, diarrhea;
in cases of weakened liver: possible development of hepatitis;
from the hematopoietic system: decrease in the number of leukocytes, leading to weakened immunity, platelets, reducing blood clotting, development of anemia;
allergies: Quincke's edema, skin rash;
others: fever, joint aches, flu-like. The absorption of Furadonin increases when taken with food or combined with medications that delay the release of food mass from the stomach. Therefore, it is better for pregnant women to take it separately.

Some sources indicate that Furodonin can be used, but only in the second trimester.

To reduce possible side effects, there are a number of rules for taking Furadonin:

take Furadonin as prescribed by a doctor, based on an analysis of pathological flora;
take each dose of medication with a glass of clean water;
do not delay emptying the bladder;
take a repeat flora test after 3 days of taking the medicine, if it shows that acute inflammation has been relieved, switch to herbal remedies or homeopathic remedies;
use the drug only after 12 weeks of pregnancy.

Many medications are contraindicated during pregnancy. Some are allowed with restrictions. Of course, during the period of bearing a child, it is advisable to completely abandon medications. But diseases do not go away on their own, especially those that require the use of antibacterial drugs.

Diseases

During pregnancy, a woman may encounter various diseases - bronchitis, pneumonia, pyelonephritis. Moreover, the likelihood of developing them during this period is higher due to a certain immunodeficiency caused by bearing a child.

But on the other hand, the expectant mother, as a rule, takes her health more seriously, for fear of harming the child. She avoids contact with sick people, hypothermia, and exacerbation of chronic diseases.

However, there are pathologies that occur much more often during pregnancy due to changes occurring in the female body. We are talking about inflammation of the bladder - cystitis. For the development of this disease, the expectant mother has favorable conditions:

Pressure of the growing uterus on the bladder.
Weakening of the immune system.
Asymptomatic bacteriuria, which is often found in a general urine test in humans, but during pregnancy threatens the development of acute inflammation.

Untreated cystitis is fraught with the spread of inflammation to the kidney area - pyelonephritis, therefore antibacterial drugs are necessarily used in therapy. Quite often, doctors prescribe drugs of the nitrofuran group. The most popular among them is Furadonin.

Furadonin

The active ingredient of Furadonin is nitrofurantoin. This drug belongs to the group of nitrofurans, synthetic antibacterial drugs. They replaced sulfonamides, the first antiseptics. Unlike the latter, nitrofurans have fewer side effects and are easier to tolerate.

However, if we compare them with modern antibacterial drugs, they are inferior in effectiveness to most of them. What explains such commitment of doctors to treatment with Furadonin and other drugs of this group?

The fact is that due to frequent treatment with strong antibiotics, microbes develop resistance to many of them, and the effectiveness of therapy is significantly reduced. In this regard, nitrofurans, and Furadonin in particular, have an undeniable advantage - bacteria practically do not become addicted to them.

Indications for the appointment of Furadonin are:

Cystitis.
Pyelitis.
Pyelonephritis.
Urethritis.
Intestinal diseases.

However, all this applies to ordinary patients. But pregnancy makes its own adjustments to the treatment of bacterial infections.

Treatment during pregnancy

As you know, the period of bearing a baby is divided into trimesters. The first and the beginning of the second trimester are considered early stages of pregnancy, the third - late. Depending on the period, restrictions on medications also change.

The first 12 weeks of pregnancy are the most important period in fetal development. Any outside interference can negatively affect the formation of organs and even systems. The minimal the drug treatment at this time, the better for the embryo.

The baby's growth continues in the second trimester, and organs begin to form. Medicines may no longer cause as much harm as in the early stages, but should still be used with caution.

Late stages of pregnancy, as a rule, allow treatment with many drugs, since the child is already formed and reliably protected from the side effects of drugs. Only some of them - for example, indomethacin - are prohibited due to a specific negative effect just before childbirth.

There are still no clear recommendations regarding treatment with Furadonin during pregnancy.

Early dates

You should not take these pills in the first trimester. The risk of negative influence of Furadonin on the development of the embryo is too great. Although according to the FDA classification this drug is classified as group B.

This division of drugs into groups A, B, C, D in the USA is used in obstetrics and gynecology in the treatment of pregnant women. Belonging to group B means that the drug has not demonstrated any negative effects on embryo development in animal tests. But studies on pregnant women were not conducted for ethical reasons.

For an expectant mother, treatment with Furadonin may result in the development of the following complications:

Allergic reactions.
Vomiting and diarrhea.
Dizziness and headache, damage to peripheral nerves.
Increased levels of liver enzymes - transaminases and drug-induced hepatitis. Considering that during pregnancy the load on the liver doubles, this effect of nitrofurantoin is extremely undesirable.
Damage to the lungs with the occurrence of pneumonitis. This specific complication is characteristic only of Furadonin.
Blood diseases - hemolytic and megaloblastic anemia, leukopenia.

Mid pregnancy

In the second trimester, nitrofuran drugs and Furadonin, in particular, are approved for use. This applies to Russia and neighboring countries. It is believed that during this period the medicine will not harm the baby’s development.

However, the side effects of nitrofurantoin do not disappear during this period, and it can still be difficult for the patient to tolerate. The decision to prescribe a medicine is made by the doctor, taking into account the data of the antibiogram and the potential harm of all drugs to which the pathogen is sensitive.

Do not forget that Furadonin’s effectiveness is still incomparable with modern antibiotics, so it is, as a rule, not used for the treatment of pyelitis and pyelonephritis. Most often, only cystitis is treated with this drug.

Late dates

The third trimester of pregnancy is an official contraindication for treatment with Furadonin. In this situation, the toxic effect of the drug on the child’s blood system plays a significant role.

It was noted that therapy with this medicine can cause the baby to develop hemolytic anemia, which in the future threatens the appearance of jaundice, hypoxia and other complications.

Treatment with Furadonin in the later stages should be avoided at all costs. The only exceptions are those situations when the pathogen is sensitive to this particular drug or antibiotics, which can cause even more harm to the child and mother. However, this rarely happens, since determining the sensitivity of microbes to antibacterial drugs includes a fairly extensive list of drugs from different groups.

If the doctor nevertheless decides to treat the expectant mother with Furadonin, it is necessary to monitor the condition of the blood system every 5–7 days.

Analogues

If Furadonin is not recommended for use in pregnant women in the first and third trimesters, what other drugs can treat pathology of the urinary system?

In the first trimester, Monural with the active ingredient fosfomycin worked well. Its main advantage is its excellent tolerability and single dose. However, it should be borne in mind that the effect of the medicine takes place over several days, and during this period the symptoms of cystitis may persist.

If therapy requires the use of more serious antibacterial drugs, during pregnancy you can use Augmentin, a medicine from a number of protected penicillins. It is recommended for the treatment of diseases of the respiratory and urinary systems, as well as infectious diseases of the skin and soft tissues.

Furadonin is not a first-line drug during pregnancy. Moreover, such treatment should be avoided whenever possible, especially in the first and third trimesters. This medicine can be used only if the pathogen is resistant to other drugs.

During the period of gestation, a woman’s immunity and her body are weakened - this creates a favorable environment for infection by all kinds of diseases. But since one or another medication should be taken with caution during pregnancy, it is important to understand whether Furadonin can be taken, what restrictions and indications there are.

General information about the drug

Should pregnant women take Furadonin?

It is enough to note that group B drugs are most often prescribed to expectant mothers and women during lactation - and during this period there are restrictions and indications, rules and dosages of administration. This drug is prescribed exclusively by a doctor, after a microbiological study.- most often this is urine culture, which will allow us to determine the causative agent of the pathological process and the level of its sensitivity to the active components of the medicinal composition.

Regarding the method of use of the drug and dosage, take Furadonin orally with a sufficient amount of water. The dosage of the drug per day is 0.1 - 0.15 g 3-4 times a day, depending on the degree of the disease. The maximum permissible daily dosage of the drug should not exceed 0.6 mg, while a single dosage should not exceed 0.3 mg. The duration of the course of treatment is 7-10 days, subject to the acute form of the infectious process, the doctor can increase the duration of the course to 2 weeks.

Furadonin during early pregnancy is not prescribed until 12 weeks - more precisely, the drug is strictly prohibited for use in the period from 2 to 12 weeks. The thing is that during this period there is an active formation of internal organs and systems in the fetus. And therefore, even a slight influence of medications can negatively affect the unborn child, the formation of tissues and organs, systems.

If we talk about prescribing and taking the drug in later stages, the drug is prescribed from the 12th week of pregnancy and after agreeing on the dosage and duration of the course, based on the results of laboratory tests. In this case, the doctor prescribes the drug if the positive therapeutic effect prevails over possible negative consequences, comparing the data with how critical the inflammation of the genitourinary system, the urinary duct in a woman and the functioning of the kidneys are.

Indications and contraindications

Regarding the indications for taking Furadonin during pregnancy, doctors and manufacturers highlight the following points:

As the main drug for the treatment of infectious and inflammatory origin of pathology affecting the urinary tract, suppression of pathogenic microflora sensitive to the active components of Furadonin - pyelitis and urethritis.
For the prevention and prevention of recurrence of infectious pathologies during operations on the genitourinary system, as well as cystoscopy and catheter placement.

Most often, this drug is prescribed if bacteria and pathogenic fungi that provoke inflammation cannot be effectively treated with less toxic medications.

Regarding existing contraindications, developers and doctors name the following points and restrictions:

A pronounced malfunction of the liver and kidneys.
When diagnosing congenital G6PD deficiency in a patient.
During severe forms of the cardiovascular system.
Doctors also call individual intolerance and hypersensitivity to the medicinal composition and active ingredients a limitation to the prescription.

Possible side effects

Regarding the side effects of taking Furadonin during pregnancy, these may be:

Respiratory system - side effects show themselves as coughing attacks and pain in the sternum, shortness of breath and pulmonary edema, less often - a deterioration in the general condition of all those who suffer from bronchial asthma.
The gastrointestinal tract may show loss of appetite and vomiting, attacks of nausea and diarrhea, less often the liver is affected, after which hepatitis develops.
From the side of the central nervous system - attacks of dizziness and migraines, general weakness also manifests itself.
Anemia develops and the total number of leukocytes decreases, and bleeding may increase.
Allergic skin rashes, urticaria and itching also show themselves, with more serious intoxication of the body - anaphylactic edema of the larynx.
Doctors include other negative consequences and side effects from taking the drug: increased body temperature, pain in the joints, when bones ache like a cold.

To avoid negative consequences, you should not practice self-medication.